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| 1 | Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients. | Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder | 2009 | World Journal of Gastroenterology2009，15，9： | 6 |
| 2 | Evaluation of three-dimensional biofilms on antibacterial bonding agents containing novel quaternary ammonium methacrylates显示文摘Antibacterial adhesives are promising to inhibit biofilms and secondary caries.The objectives of this study were to synthesize and incorporate quaternary ammonium methacrylates into adhesives,and investigate the alkyl chain length effects on three-dimensional biofilms adherent on adhesives for the first time.Six quaternary ammonium methacrylates with chain lengths of 3,6,9,12,16 and 18were synthesized and incorporated into Scotchbond Multi-Purpose.Streptococcus mutans bacteria were cultured on resin to form biofilms.Confocal laser scanning microscopy was used to measure biofilm thickness,live/dead volumes and live-bacteria percentage vs.distance from resin surface.Biofilm thickness was the greatest for Scotchbond control;it decreased with increasing chain length,reaching a minimum at chain length 16.Live-biofilm volume had a similar trend.Dead-biofilm volume increased with increasing chain length.The adhesive with chain length 9 had 37%live bacteria near resin surface,but close to 100%live bacteria in the biofilm top section.For chain length 16,there were nearly 0%live bacteria throughout the three-dimensional biofilm.In conclusion,strong antibacterial activity was achieved by adding quaternary ammonium into adhesive,with biofilm thickness and live-biofilm volume decreasing as chain length was increased from 3 to 16.Antibacterial adhesives typically only inhibited bacteria close to its surface;however,adhesive with chain length 16 had mostly dead bacteria in the entire three-dimensional biofilm.Antibacterial adhesive with chain length 16 is promising to inhibit biofilms at the margins and combat secondary caries. | Han Zhou Michael D Weir Joseph M Antonucci Gary E Schumacher Xue-Dong Zhou Hockin H K Xu | 2014 | International Journal of Oral Science2014，6，2： | 5 |
| 3 | Successful operation of a cooperative SLR station of China and Argentina in San Juan显示文摘We introduced the observations and researches using a Satellite Laser Ranging (SLR) system with high precision, which was designed and made in China and installed in the Observatory of San Juan Uni- versity, Argentina, the capability of the system and the achievement of the cooperative procedure be- tween China and Argentina. The SLR station in San Juan, set up by China and Argentina, is quite sig- nificant for improving the distribution of SLR stations and enhancing the orbital coverage of the whole earth. Since the SLR system started to work in the Observatory of San Juan University in the beginning of 2006, the operation is rather good, and rich data with high precision have been obtained. Further plan of the cooperation for the near future is also presented. | HAN YanBen LIU WeiDong E ACTIS R PODESTA WANG TanQiang GUO TangYong QU Feng A M PACHECO A A GONZALEZ E ALONSO XIANG QingGe HUANG DongPing YIN ZhiQiang | 2008 | Chinese Science Bulletin2008，53，16： | 2 |
| 4 | STATCOM impact study on the integration of a large wind farm into a weak loop power system显示文摘 | HAN Chong HUANG A Q BARAN M E | 2008 | IEEE Transactions on Energy Conversion2008，23，1： | 1 |
| 5 | Clinical outcomes after lumbar discectomy for sciatica: the effects of fragment type and anular competence显示文摘 | Carragee E J Han M Y Suen P W | 2003 | J Bone Joint Surg Am2003，85，1： | 1 |
| 6 | Molecular basis for the herbicide resistance of roundup ready crops显示文摘 | Todd F Han H J Healy-Fried M L Fischer M Schnbrunn E | 2006 | Proceedings of the National Academy of Sciences of the United States of America2006，，13： | 1 |
| 7 | Regeneration of a transgenic woody Legume (Robinia pseudoacacia L,black Locust) andmorphological alterations inducedby Agrobacterium rhiaogenes-mediatedtransformaion显示文摘 | HAN K H KEATHLEY D E DAVIS J M | 1993 | Plant Sci1993，88，2： | 1 |
| 8 | An uhrastrac-tural analysis of the prototype single step adhesive appliedon enamel and dentin surfaces显示文摘 | HAN L CRUE E FUKUSHIMA M | 2004 | Dent Mater2004，23，3： | 1 |
| 9 | Vehicle routing under time-dependent travel times: the impact of congestion avoidance显示文摘 | A L Kok E W Hans J M J Schutten | 2012 | Computers & Operations Research2012，39，5： | 1 |
| 10 | Metabolism of 20 (S)-and 20(R)-ginsenoside Rg3 by human intestinal bacteria and relation to in vitro biological activities 显示文摘 | Bae E A Han M J Choo M W K | 2002 | Biol Pharm Bull2002，25，1： | 1 |
| 11 | Randomised comparison of combined step-down prednisolone, methotrexate and sulphasalazine with sulphasalazine alone in early rheumatoid arthritis显示文摘 | Maarten Boers Arco C Verhoeven Harry M Markusse Mart AFJ van de Laar Rene Westhovens J Christiaan van Denderen Derkjen van Zeben Ben AC Dijkmans Andre J Peeters Piet Jacobs Hans R van den Brink Hubert JA Schouten Désirée MFM van der Heijde Annelies Boonen | 1997 | The Lancet1997，，9074： | 1 |
| 12 | Workload based order acceptance in job shop environments显示文摘 | EBBEN M HANS E WEGHUIS O F M | 2005 | OR Spec- trum2005，16，2： | 1 |
| 13 | High resolution maps from wide angel sonar 显示文摘 | Hans M Alberto E | 1985 | The IEEE International Conference on Robotics and Automation1985，，： | 1 |
| 14 | Surface deformation due to loading of a layered elastic half-space:a rapid numerical kernel based on a circular loading element显示文摘 | PAN E BEVIS M HAN F | 2007 | Geophysical Journal International2007，171，1： | 1 |
| 15 | A whole life cycle assessment on effects of waterborne PBDEs on gene expression profile along the brain- pituitary-gonad axis and in the liver of zebrafish 显示文摘 | Han XB Lei E Lam M | 2011 | Marie Pollut Bullet2011，63，： | 1 |
| 16 | Obesity and weight management in the elderly:a focus on men显示文摘 | Han T S Wu F C Lean M E | 2013 | Best Practice&Research Clinical Endocrinology&Metabolism2013，27，4： | 1 |
| 17 | A microRNA embedded AVV alpha-synuclein gene silencing vectoR foR dopaminergic neurons显示文摘 | Han Y KhodR C E Sapru M K | 2011 | Brain Res2011，1386，： | 1 |
| 18 | Study on the alkylation of benzene with propylene over Hβ-zeolite显示文摘 | HAN M LIN S RODUNER E | 2003 | Appl Catal A2003，243，1： | 1 |
| 19 | Cloning,sequencing and expression of an Escherichia coli acid phosphatase/phytase gene(appA2)isolated from pig colon显示文摘 | RODRIGUEZ E HAN Y M LEI X G | 1999 | Biochem Biophys Res Commun1999，257，： | 1 |
| 20 | Plastic ELISA-on-a-chip based on sequential cross-flow chromatography 显示文摘 | Cho J H Han S M Paek E H | 2006 | Anal Chem2006，78，3： | 1 |
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