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| 1 | Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients. | Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder | 2009 | World Journal of Gastroenterology2009，15，9： | 6 |
| 2 | Protective role of PI3-kinase/Akt/eNOS signaling in mechanical stress through inhibition of p38 mitogenactivated protein kinase in mouse lung显示文摘 | Xin-qi PENG Mahendra DAMARLA Jarrett SKIRBALL Stephanie NONAS Xiao-ying WANG Eugenia J HAN Emile J HASAN Xuan CAO Adel BOUEIZ Rachel DAMICO Rubin M TUDER Alfred M SClUTO Dana R ANDERSON Joe GNGARCIA David A KASS Paul M HASSOUN Jun-tian ZHANG | 2010 | Acta Pharmacologica Sinica2010，31，2： | 6 |
| 3 | Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn’s disease: an open randomised trial显示文摘 | Geert D’Haens Filip Baert Gert van Assche Philip Caenepeel Philippe Vergauwe Hans Tuynman Martine De Vos Sander van Deventer Larry Stitt Allan Donner Severine Vermeire Frank J Van De Mierop Jean-Charles R Coche Janneke van der Woude Thomas Ochsenkühn Ad A | 2008 | The Lancet2008，，9613： | 5 |
| 4 | Successful operation of a cooperative SLR station of China and Argentina in San Juan显示文摘We introduced the observations and researches using a Satellite Laser Ranging (SLR) system with high precision, which was designed and made in China and installed in the Observatory of San Juan Uni- versity, Argentina, the capability of the system and the achievement of the cooperative procedure be- tween China and Argentina. The SLR station in San Juan, set up by China and Argentina, is quite sig- nificant for improving the distribution of SLR stations and enhancing the orbital coverage of the whole earth. Since the SLR system started to work in the Observatory of San Juan University in the beginning of 2006, the operation is rather good, and rich data with high precision have been obtained. Further plan of the cooperation for the near future is also presented. | HAN YanBen LIU WeiDong E ACTIS R PODESTA WANG TanQiang GUO TangYong QU Feng A M PACHECO A A GONZALEZ E ALONSO XIANG QingGe HUANG DongPing YIN ZhiQiang | 2008 | Chinese Science Bulletin2008，53，16： | 2 |
| 5 | Sand dunes as potential sources of dust in northern China显示文摘While saltation bombardment of sand grains on a fine substrate can produce considerable dust, the well-sorted nature of sand dunes tends to preclude them from consideration as major dust sources. Recent research, however, has revealed that sand dunes can, in some cases, be large sources of dust. We used the PI-SWERL(Portable In-Situ Wind Erosion Laboratory) to measure in the field the potential of sand dunes and other desert landforms to emit particulate matter <10 μm(PM-10) dust in the Tengger, Ulan Buh, and Mu Us deserts of northern China. Combined with high resolution particle size measurements of the dune sand, an assessment of sand dunes as a dust source can be made. Large active transverse dunes tend to contain little to no stored PM-10, yet they produce a low dust flux. Coppice dunes stabilized by vegetation contain appreciable PM-10 and have very high dust emission potential. There is a positive correlation between the amount of PM-10 stored in a dune and its potential dust flux. Saltation liberates loose fines stored in dunes, making them very efficient dust emitters compared to landforms such as dry lake beds and washes where dust particles are unavailable for aeolian transport due to protective crusts or sediment cohesion. In cases where large dunes do not store PM-10 yet emit dust when active, two hypotheses can be considered:(1) iron-oxide grain coatings are removed during saltation, creating dust, and(2) sand grains collide during saltation, abrading grains to create dust. Observations reveal that iron oxide coatings are present on some dune sands. PI-SWERL data suggests that low dust fluxes from dunes containing no stored dust may represent an estimate for the amount of PM-10 dust produced by removal of iron oxide coatings. These results are similar to results from dunes in the United States. In addition, PI-SWERL results suggest that dust-bearing coppice dunes, which cover vast areas of China's sandy deserts, may become major sources of dust in the future if overgrazing, depletion of groundwater, or drought destabilizes the vegetation that now partially covers these dunes. | Mark R SWEENEY LU HuaYu CUI MengChun Joseph A MASON FENG Han XU ZhiWei | 2016 | Science China Earth Sciences2016，59，4： | 2 |
| 6 | Red River and associated faults,Yunnan Province,China:Quaternary geology,slip rates and seismic hazard显示文摘 | ALLEN C R GILLESPIE A R HAN Y | 1984 | Geological Society of America Bulletin1984，95，： | 1 |
| 7 | Virtual reality-based post-stroke hand rehabilitation 显示文摘 | Boian R Sharma A Han C | 2002 | Stud Health Technol Inform2002，85，1： | 1 |
| 8 | Two-photon-excited fluorescence imaging of human RPE cells with a femtosecond Ti: Sapphire laser显示文摘 | Bindewald-Wittich A Han M Schmitz-Valckenberg S Snyder Sar- ah R Giese G Bille Josef F | 2006 | Invest Ophthalmol Vis Sci2006，47，10： | 1 |
| 9 | Adenosine triphosphate-binding cassette transporter genes up regulation in untreated hepatocellular carcinoma is mediated by cellular microRNAs显示文摘 | Borel F Han R Visser A | 2012 | Hepatolo- gy2012，55，3： | 1 |
| 10 | B io a v a ila b ility andpopulation pharm acokinetics o f voriconazole in lungtransplant recipien ts 显示文摘 | Han K C apitano B B ies R et a l | 2010 | Antimicrob Agents Chemother2010，54，10： | 1 |
| 11 | Real-time dependable channels:customizing QoS attributes for distributed systems显示文摘 | HILTUNEN M A SCHLICHTING R D HAN Xiao-nan | 1999 | IEEE Trans on Parallel and Distributed Systems1999，10，6： | 1 |
| 12 | Palladium-catalyzed dehydrogenative cross-couplings of benzazoles with azoles显示文摘 | Han W Mayer P Ofial A R | 2011 | Angew Chem Int Ed2011，50，9： | 1 |
| 13 | Fractal dimension as ameasure of altered actin cytoskeleton in MC3T3-E1 cells un-der simulated microgravity using 3-D/2-D clinostats 显示文摘 | QIAN A R LI D HAN J | 2012 | IEEE Trans Biomed Eng2012，59，5： | 1 |
| 14 | Colorimetric Screening of DNA-Binding Molecules with Gold Nanoparticle Probes显示文摘 | Han M S Lytton-Jean A K R Mirkin C A | | 0，，： | 1 |
| 15 | Colorimetric screening of DNA-binding molecules with gold nanoparticle probes显示文摘 | HAN M S LYTTON-JEAN A K R OH B K | 2006 | Angewandte Chemie-International Edition2006，45，11： | 1 |
| 16 | Spinodal dewetting of thin polymer films 显示文摘 | Xie R Karim A Douglas J F Han C C Weiss R A | 1998 | Physical Review Letters1998，81，： | 1 |
| 17 | Grain growth in Mn- doped ZnO显示文摘 | Han J Mantas P Q Senos A M R | 2000 | J Eur Ceram Soc2000，20，16： | 1 |
| 18 | A Proposed Mechanism of Tenderizing Post-rigor Beef Using High Pres- sure-heat Treatment 显示文摘 | NADARAJAH A HAN J H HOLLEY R A | 2005 | International Journal of Food Mi- crobiology2005，99，： | 1 |
| 19 | Necessary and sufficient conditions for oscillations of delay equations with impulses显示文摘 | Zhao A M Han M Yan J R | 1997 | J Appl Math Lett1997，10，： | 1 |
| 20 | Chaotic motion of a horizontal impact pair显示文摘 | Han R P S Luo A C J Deng W | 1995 | Journal of Sound and Vibration1995，181，2： | 1 |
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