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| 1 | Assessment of the Ecological Security in the Three Gorges Reservoir Area by Using the Ecological Footprint Method显示文摘The ecological footprint concept and its calculation models are useful for the measurement of the sustainable level of social and economic development.The ecological security situation of the Three Gorges Reservoir Area(TGRA) was evaluated using this concept in this study.The construction of the Three Gorges Reservoir has led to the change in the ecology and immigration status of TGRA.The ecological footprint method is an important means to study the regional ecological security.Our results suggested that,by excluding the areas for biodiversity conservation(12% of the total land),the ecological footprint per capita was 0.57895 ha,which exceeded the ecological carrying capacity in TGRA.The total ecological deficit was found to be 11,522,193.34 ha,accounting for 95.02% of the ecological carrying capacity.These findings suggested that the ecological security of TGRA was not good.In order to compensate for the ecological deficit,it was essential to introduce natural resources from other regions. | WANG Haiming WANG Hai'e SUN Hongyang WANG Xiaolan LIAO Xiaoyong CHEN Zhijian LI Xianwei | 2012 | Journal of Mountain Science2012，9，6： | 9 |
| 2 | Improvement of antibacterial activity of copper nanoclusters for selective inhibition on the growth of gram-positive bacteria显示文摘In general, copper nanoclusters (CuNCs) possess very low or even virtually no bactericidal effect. Herein,we report a novel CuNCs possessing significantly high antibacterial activity, that is tannic acid (TA)capped CuNCs (TA-CuNCs). TA-CuNCs exhibit strong absorption and excitation-dependent fluorescence within pH 2-12, resulting from the functional groups of TA-CuNCs due to two prototropic equilibria,phenolphenolate and carboxyliccarboxylate. There exists synergistic effect of TA and copper nanoclusters which endows TA-CuNCs remarkable antibacterial capability as a microbicide, as characterized by the effective inhibition on the growth of gram-positive bacteria by damaging the cell membrane. By incubating 1 x 10~7 CFU/mL of gram-positive bacteria Staphylococcus aureus and Bacillus subtilis with 30 μg/mL of TA-CuNCs for 10 min, the bacteria are completely inhibited, while under same conditions the viabilities of gram-negative bacteria Escherichia coli 0157:H7 and Pseudomonas aeruginosa remain 85.0%, 72.0%, respectively. In addition, TA-CuNCs exhibit low cytotoxicity and favorable biocompatibility demonstrated by standard methyl thiazolyl tetrazolium (MTT) assay with HepG2 and 293 Tcells, giving rise to cell viability of 94.2% for HepG2 and 96.7% for 293 T by incubating 10~6 cell/mL with 200 μg/mL of TA-CuNCs for 24 h. These results make TA-CuNCs a potential alternative as bactericide for infection treatment caused by gram-positive bacteria. | Junmei Xia Wenjing Wang Xin Hai Shuang E Yang Shu Jianhua Wang | 2019 | Chinese Chemical Letters2019，30，2： | 2 |
| 3 | Communicating with chaos显示文摘 | HAYS S GREBOGI C OTT E | 1993 | Phys Rev Lett1993，70，20： | 2 |
| 4 | Neoadjuvant therapy for resectable pancreatic ductal adenocarcinoma: The need for patient-centered research显示文摘Pancreatic ductal adenocarcinoma is an aggressive cancer with high recurrence rates following surgical resection.While adjuvant chemotherapy improves survival,a significant proportion of patients are unable to initiate or complete all intended therapy following pancreatectomy due to postoperative complications or poor performance status.The administration of chemotherapy prior to surgical resection is an alternative strategy that ensures its early and near universal delivery as well as improves margin-negative resection rates and potentially improves long-term survival outcomes.Neoadjuvant therapy is increasingly being recommended to patients with pancreatic ductal adenocarcinoma,however,patient-centered research on its use is lacking.In this review,we highlight opportunities to focus research efforts in the domains of patient preferences,patient-reported outcomes,patient experience,and survivorship.Novel research in these areas may identify relevant barriers and facilitators to the use of neoadjuvant therapy thereby increasing its utilization,improve shareddecision making for patients and providers,and optimize the experience of those undergoing neoadjuvant therapy. | Jordan M Cloyd Allan Tsung John Hays Celia E Wills John FP Bridges | 2020 | World Journal of Gastroenterology2020，26，4： | 2 |
| 5 | Optimization of Texture Determination of ‘Yali' by Texture Analyzer显示文摘[Objectives] This study was carried out to determine texture parameters for texture profile analysis( TPA),and optimize the texture determination of‘Yali'by texture analyzer. [Methods]The traditional varieties of‘Yali'were taken as the materials,and texture parameters were determined at different compression rates and deformations at target. [Results]In the process of the TPA,the deformation at target had an extremely significant influence on 8 TPA texture parameters,namely,the hardness,cohesiveness,springiness,adhesiveness,gumminess,resilience,fracturability,and chewiness( P≤0. 01),while the compression rate had significant influence on the hardness and gumminess( P≤0. 05),had an extremely significant influence on fracturability( P≤0. 01),and had no significant influence on other 5 TPA parameters. [Conclusions]Taking the compression rate of 1 mm/s and 20% deformation at target as the experimental conditions for TPA could avoid the impact load of high speed on the tissue and objectively reflect the textural characteristics of‘Yali'pulp tissue. | Jintao XU Lijuan GAO Longfei LI Hai'e ZHANG Wenquan LE Baofeng HAO | 2018 | Agricultural Biotechnology2018，7，4： | 2 |
| 6 | A clinical evaluation of transdermal therapeutic system fentanyl for the treatment of cancer pain显示文摘 | Sloan Pa Moulin D E Hays H | 1998 | J Pain Symptom Manage1998，16，2： | 1 |
| 7 | The triterpenoid CDDO inhibits expression of matrix metalloproteinase-1,matrix metalloproteinase-13 and Bcl-3 in primary human chondrocytes显示文摘 | Elliott S Hays E Mayor M | 2003 | Arthritis Res Ther2003，5，5： | 1 |
| 8 | Secretory and internalization pathways of mosquito yolk protein precursors显示文摘 | Snigirevskaya E S Hays A R Raikhel A S | 1997 | Cell Tissue Res1997，290，： | 1 |
| 9 | The cost of crime to society: New crime-specific estimates for policy and program evaluation显示文摘 | Kathryn E Mccollister Michael T French Hai Fang | 2010 | Drug and Alcohol Dependence2010，108，1： | 1 |
| 10 | RelA is required for IL-1beta stimulation of Matrix Metalloproteinase-1 ex-pression in chondrocytes显示文摘 | Raymond L Eck S Hays E | | 0，，： | 1 |
| 11 | Deformation twinning at aluminum crack tips 显示文摘 | Hai S Tadmor E B | 2003 | Acta Mater2003，51，： | 1 |
| 12 | The MOS short-form general health survey: reliability and validity in a patient population显示文摘 | Stewart A L Hays R D Ware J E Jr | 1988 | Med Care1988，26，7： | 1 |
| 13 | Immobilization modulates macrophage accumulation in tendon- bone healing显示文摘 | Dangher E Hays PL Kawamura S | 2009 | Clin Orthop2009，467，1： | 1 |
| 14 | A Peierls criterion for the onset of deformation twinning at a crack tip 显示文摘 | Tadmor E B Hai S | 2003 | J Mech Phys Solids2003，51，： | 1 |
| 15 | Analysis of Knoop microhardness显示文摘 | Hays C Kendall E G | 1973 | Metallography1973，6，4： | 1 |
| 16 | MP Bcl-3 is an interleukin-1-responsive gene in chondrocytes and synovial fibroblasts that activates transcription of the matrix metalloproteinase 1 gene显示文摘 | Elliott SF Coon CI Hays E | 2002 | Arthritis Rheum2002，46，12： | 1 |
| 17 | Treatment of Snoring and Obstructive Sleep Apnea with a Dental Orthosis 显示文摘 | Schmidt Nowara W W Meade T E Hays M B | 1991 | Chest1991，99，6： | 1 |
| 18 | The prospective effect of medical care on health-related quality of life outcomes in patients with symptomatic HIV disease显示文摘 | CUNNINGHAM W E HAYS R D ETTL M K et at | 1998 | Med Care1998，46，： | 1 |
| 19 | A model for optimal delivery time guarantees 显示文摘 | Hill A V Hays J M Naveh E | 2000 | Journal of Service Research2000，2，3： | 1 |
| 20 | A model for optimal delivery time guarantees显示文摘 | Hill A V Hays J M Naveh E | | 0，，03： | 1 |
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