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78篇 您的检索式:作者名="Healey H"
    题名 作者 年代 出处 被引量
1骨肉瘤成骨细胞表型与临床因素的相关性研究显示文摘目的采集手术切除未经培养的骨肉瘤标本,研究肿瘤中成骨细胞的分化及其与临床因素的关系。方法观察骨肉瘤中成骨细胞相关基因表达的频率、特异性,以及骨肉瘤成骨细胞表型与生物学行为的关系。应用RT-PCR方法研究48例骨肉瘤标本的碱性磷酸酶(ALP)、骨钙素(OC)和骨桥蛋白(ON)的mRNA转录。磷酸甘油酸激酶(PGK)被用于内参照。结果在大多数骨肉瘤标本中可以发现ALP或OC的mRNA转录(分别为93.75%,79.17%)。在所有的肉瘤检测中均可发现ON的mRNA转录。在骨肉瘤的成骨细胞亚型中可见到ALP和OC的高水平表达。肺转移瘤OC的mRNA表达弱于原发灶。肿瘤细胞有高水平OC表达的病例组有较高的生存率(P=0.045)。结论OC是目前最好的成骨细胞特异性标记物,将来可能用于检测骨肉瘤患者外周血中循环的肿瘤细胞。郭卫 John H Healey 2002中华骨科杂志2002,22,7:2
2Modeling and classifying color textures using random fields in a random environment显示文摘SUEN P H HEALEY G 1999Pattern Roeognition1999,32,6:1
3Osteoarthrosis and con- genital dysplasia of the hip in family members of children who have congenital dysplasia of the hip显示文摘HOAGLUND F T HEALEY J H 1990J Bone Joint Surg Am1990,3,4:1
4SYT-SSX genefusion as a determinant of morphology and prognosis in synovial sarcoma显示文摘Kawai A Woodruff J Healey J H 1998New Eng J Med1998,338,:1
5Pacemaker or defibrillator 'surgery without interrup- tion of anticoagulation显示文摘BIRNIE D H HEALEY J S WELLS G A 2013N Engl J Med2013,368,:1
6Preventable deaths due toproblems in care in English acute hospitals : a retrospective case re-cord review study显示文摘Hogan H Healey F Neale G 2012BMJ Qual Saf2012,21,9:1
7Dickkopf 3 inhibits invasion and motility of Saos-2 osteosarcoma cells by modulating the Wnt-beta-catenin pathway 显示文摘HOANG B H KUBO T HEALEY J H 2004Cancer Res2004,64,8:1
8SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma显示文摘Kawai A Woodmff J Healey J H 1998New Eng J Med1998,338,:1
9Osteogenic and Ewing sarcomas: estimation of necrotic fraction during induction chemotherapy with dynamic contrast -enhanced MR imaging显示文摘DYKE J P PANICEK D M HEALEY J H 2003Radiology2003,228,1:1
10Comparison of the effects of transfusins of cryopreserved and liguid preserved platelets on hemostasis and blood loss after cardiopulmonary bypass显示文摘 Healey N Mac Gregor H 1999J Thorac Surg1999,117,1:1
11Comparison of the effect soft transfusions of cryopreserved and liquid-oreserved platelets on hemostasis and blood loss after eardio pulmonary bypass显示文摘 Healey NM acGregor H 1999J Thome Cardio vase Surg1999,117,1:1
12Canal configu- ration in the mesiobuccal root of the maxillary first mo- lar and its endodontic significance显示文摘Weine FS Healey HJ Gerstein H 1969Oral Surg Oral Med Oral Pathol1969,28,3:1
13The detection of cervical intraepithelial neoplasia by electrical impedance spectroscopy : The effects of acetic acid and tissue homogeneity 显示文摘Balasubramani L Brown B H Healey J 2009Gynecologic Oncology2009,115,:1
14Canal configuration in themesiobuccal root of the maxillary first molar and its endodontic sig-nificance显示文摘Weine FS Healey HJ Gerstein H 1969Oral Surg Oral Med Oral Pathol1969,28,3:1
15Preventable deaths due to prob- lem in care in English aeute hospital:A retrospective case record re- view study显示文摘Hogan H Healey F Neale G 2012BMJ Qual Saf2012,21,9:1
16Comparison of the effeets of transfusions of eryopreserved and liquid-preserved platelets on hemostasis and blood loss after cardiopulmonary bypass显示文摘Khuri SF Healey N Macgregor H 1999J Thorac Curdiovasc Surg1999,177,1:1
17Osteoporosis in unstable adult seoliosis显示文摘VELIS K P HEALEY J H SCHNEIDER R 1988Clin Orthop Relat Res1988,,237:1
18Face recognition in hyper spectral images显示文摘Pan Z H Healey G Prasad M 2003IEEE Transactions on Pattern Analysis and Machine Intelligence2003,25,12:1
19Canal configuration in the mesiobuccal root of the maxillary first molar and its endodontic significanc显示文摘 Healey JH Gerstein H 1969Oral Surg Oral Med Oral Pathol1969,28,:1
20Metachronous skeletal osteosarcoma in patients treated with adjuvant and neoadjuvant chemotherapy for nonmetastatic osteosarcoma显示文摘AUNG L GORLICK R HEALEY J H 2003J Clin Oncol2003,21,2:1
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