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| 1 | 8760例住院患者人血白蛋白临床使用分析与评价显示文摘目的:为人血白蛋白临床合理使用提供参考。方法:回顾性调查我院2014年1-12月使用人血白蛋白的住院患者病例,统计患者一般资料、用药前血清白蛋白水平、用药量、费用、用药原因等信息,并进行分析。结果:人血白蛋白使用人数最多的8个科室共8 760例患者纳入研究,占全院使用人血白蛋白住院患者的64%。其中,男性5 244例(占59.9%),女性3 516例(占40.1%),患者年龄主要集中在>30~60岁(占52.6%)。白蛋白使用人数最多的科室为普通外科(2 588例)和心血管外科(2 348例)。以国内说明书作为参照标准时,该院有8 210例(约93.7%)患者符合适应证,低蛋白血症为最常见的用药指征(占35.6%)。重症监护治疗病房人均使用量最高(152.5 g),普通外科总用药金额最高(13 334 396.4元),传染科人均使用疗程最长(10.7 d)。结论:我院存在人血白蛋白不合理使用情况,科室间使用情况存在差异。应加强对人血白蛋白使用的监督,建立合理的用药评估体系,以促进用药规范,实现医疗资源合理分配。 | 曾晶 徐萍 王清 朱艳 原海燕 肖轶雯 Andrew Cave Hoan Linh Banh | 2017 | 中国药房2017，28，8： | 18 |
| 2 | Production of global land cover data-GLCNMO显示文摘Global land cover is one of the fundamental contents of Digital Earth.The Global Mapping project coordinated by the International Steering Committee for Global Mapping has produced a 1-km global land cover datasetGlobal Land Cover by National Mapping Organizations.It has 20 land cover classes defined using the Land Cover Classification System.Of them,14 classes were derived using supervised classification.The remaining six were classified independently:urban,tree open,mangrove,wetland,snow/ice,andwater.Primary source data of this land cover mapping were eight periods of 16-day composite 7-band 1-km MODIS data of 2003.Training data for supervised classification were collected using Landsat images,MODIS NDVI seasonal change patterns,Google Earth,Virtual Earth,existing regional maps,and expert’s comments.The overall accuracy is 76.5%and the overall accuracy with the weight of the mapped area coverage is 81.2%.The data are available from the Global Mapping project website(http://www.iscgm.org/).TheMODISdata used,land cover training data,and a list of existing regional maps are also available from the CEReS website.This mapping attempt demonstrates that training/validation data accumulation from different mapping projects must be promoted to support future global land cover mapping. | Ryutaro Tateishi Bayaer Uriyangqai Hussam Al-Bilbisi Mohamed Aboel Ghar Javzandulam Tsend-Ayush Toshiyuki Kobayashi Alimujiang Kasimu Nguyen Thanh Hoan Adel Shalaby Bayan Alsaaideh Tsevenge Enkhzaya Gegentana Hiroshi P.Sato | 2011 | International Journal of Digital Earth2011，4，1： | 11 |
| 3 | Vitamin D deficiency and hepatitis viruses-associated liver diseases:a literature review显示文摘The secosteroid hormone vitamin D has, in addition to its effects in bone metabolism also functions in the modulation of immune responses against infectious agents and in inhibiting tumorigenesis. Thus, deficiency of vitamin D is associated with several malignancies, but also with a plethora of infectious diseases. Among other communicable diseases, vitamin D deficiency is involved in the pathogenesis of chronic liver diseases caused by hepatitis B and C viruses(HBV, HCV) and high prevalence of vitamin D deficiency with serum levels below 20 mg/mL in patients with HBV and HCV infection are found worldwide. Several studies have assessed the effects of vitamin D supplementation on the sustained virological response(SVR) to interferon(IFN) plus ribavirin(RBV) therapy in HBV and HCV infection. In these studies, inconsistent results were reported. This review addresses general aspects of vitamin D deficiency and, in particular, the significance of vitamin D hypovitaminosis in the outcome of HBVand HCV-related chronic liver diseases. Furthermore,current literature was reviewed in order to understand the effects of vitamin D supplementation in combination with IFN-based therapy on the virological response in HBV and HCV infected patients. | Nghiem Xuan Hoan Hoang Van Tong Le Huu Song Christian G Meyer Thirumalaisamy P Velavan | 2018 | World Journal of Gastroenterology2018，24，4： | 9 |
| 4 | Genetic variants of interferon regulatory factor 5 associated with chronic hepatitis B infection显示文摘AIM To investigate possible effects of IRF5 polymorphisms in the 3' UTR region of the IFR5 locus on susceptibilityto hepatitis B virus(HBV) infection and progression of liver diseases among clinically classified Vietnamese patients.METHODS Four IFR5 SNPs(rs13242262 A/T, rs77416878 C/T, rs10488630 A/G, and rs2280714 T/C) were genotyped in clinically classified HBV patients [chronic hepatitis B(CHB). n = 99; liver cirrhosis(LC), n = 131; hepatocellular carcinoma(HCC), n = 149] and in 242 healthy controls by direct sequencing and Taq Man realtime PCR assays. RESULTS Comparing patients and controls, no significant association was observed for the four IFR5 variants. However, the alleles rs13242262 T and rs10488630 G contributed to an increased risk of liver cirrhosis(LC vs CHB: OR = 1.5, 95%CI: 1.1-2.3, adjusted P = 0.04; LC vs CHB: OR = 1.7, 95%CI: 1.1-2.6, adjusted P = 0.019). Haplotype IRF5*TCGT constructed from 4 SNPs was observed frequently in LC compared to CHB patients(OR = 2.1, 95%CI: 1.2-3.3, adjusted P = 0.008). Haplotype IRF5*TCAT occurred rather among CHB patients than in the other HBV patient groups(LC vs CHB: OR = 0.4, 95%CI: 0.2-0.8, adjusted P = 0.03; HCC vs CHB: OR = 0.3, 95%CI: 0.15-0.7, adjusted P = 0.003). The IRF5*TCAT haplotype was also associated with increased levels of ALT, AST and bilirubin. CONCLUSION Our study shows that IFR5 variants may contribute as a host factor in determining the pathogenesis in chronic HBV infections. | Bui Tien Sy Nghiem Xuan Hoan Hoang Van Tong Christian G Meyer Nguyen Linh Toan Le Huu Song Claus-Thomas Bock Thirumalaisamy P Velavan | 2018 | World Journal of Gastroenterology2018，24，2： | 9 |
| 5 | 头孢菌素皮试,半个世纪的误会显示文摘自从1964年礼来公司上市第一个头孢菌素——头孢噻吩以来,目前头孢菌素类抗生素已发展到第五代[1],上市品种达60多种。头孢菌素高效、低毒,临床应用非常广泛,在抗感染治疗中占有十分重要的地位。临床中头孢菌素使用前皮试比较普遍,在学术界也存在极大争议。针对目前国内头孢菌素皮试混乱现状,本文将从头孢菌素过敏性休克发生的机制,及过敏反应类型和特点、皮试的预测价值、国内外管理以及临床实践的现状. | 赵程程 Hoan Linh Banh 刘艺平 徐萍 肖轶雯 杨芳博 候成奇 | 2018 | 药学服务与研究2018，18，4： | 8 |
| 6 | Detection of Lymphomatous Bone Marrow Involvement with Magnetic Resonance Imaging显示文摘 | Hoane BR Shields AF Porter BA | 1991 | Blood1991，78，3： | 1 |
| 7 | The window of opportunity for administration of magnesium therapy following focal brain injury is 24h but is task dependent in the rat显示文摘 | Hoane MR Barth TM | 2002 | Physiology & Behavior2002，76，： | 1 |
| 8 | Magnesium therapy and recovery of function in experimental models of brain injury and neurodegenerative disease 显示文摘 | Hoane M R | 2004 | Clin Calcium2004，14，8： | 1 |
| 9 | Transumbilical laparoendoscopic single-site surgery with conventional instruments for choledochal cyst in children:early results of 86 cases显示文摘 | Son TN Liem NT Hoan VX | 2014 | J Laparoendosc Adv Surg Tech A2014，24，12： | 1 |
| 10 | The behavioral effects of magnesium therapy on recovery of function following bilateral anterior medial cortex lesion in the rat显示文摘 | Knotts AA Akstulewicz SL | 2003 | Brain Res Bu112003，60，1： | 1 |
| 11 | Fractures of calcaneus显示文摘 | Paul J Hoan VIV | 2001 | FootAn-kle Trauma2001，32，1： | 1 |
| 12 | Fractures of calcaneus显示文摘 | Paul J Hoan VIV | 2001 | Foot Ankle Trauma2001，32，1： | 1 |
| 13 | An Optimal Weight Method for CT Image Denoising显示文摘This paper proposes a novel exemplar-based method for reducing noise in computed tomography (CT) images. In the proposed method, denoising is performed on each block with the help of a given database of standard image blocks. For each noisy block, its denoised version is the best sparse positive linear combination of the blocks in the database. We formulate the problem as a constrained optimization problem such that the solution is the denoised block. Experimental results demonstrate the good performance of the proposed method over current state-of-the-art denoising methods, in terms of both objective and subjective evaluations. | Dinh Hoan Trinh Marie Luong Jean-Marie Rocchisani Canh Duong Pham Huy Dien Pham Francoise Dibos | 2012 | Journal of Electronic Science and Technology2012，10，2： | 1 |
| 14 | COG1410 improves cognitive performance and reduces cortical neuronal loss in the traumatically injured brain显示文摘 | Hoane M R Kaufman N Vitek M P | 2009 | Journal of neurotrauma2009，26，1： | 1 |
| 15 | Administration of raloxifene reduces sensorimotor and working memory deficits following traumatic brain injury显示文摘 | Olga N Kokiko Alexander K Murashov Michael R Hoane | 2006 | Behav Brain Res2006，170，2： | 1 |
| 16 | An evaluation of coal preparation technologies for controlling trace element emissions 显示文摘 | Gerald H Jaisen N Roe - Hoan | 2000 | Fuel Processing Technolog2000，，6： | 1 |
| 17 | The novel apolipepmtein E - based peptide COG1410 improves sensorimotor performance and reduces injury magnitude following conical contusion injury 显示文摘 | Hoane MR Pierce JL Holland MA | 2007 | Nerurotrauma2007，24，7： | 1 |
| 18 | Transplantation of neuronal and glial precursors dramatically improves sensorimotor function but not cognitive function in the traumatically injured brain显示文摘 | Hoane MR Becerra GD Shank JE | 2004 | J Neurotrauma2004，21，： | 1 |
| 19 | Administration of riboflavin improves behavioral outcome and reduce edema formation and GFAP expression after traumatic brain injury 显示文摘 | Hoane M R Wolyniak J G Akstulewica S L | 2005 | J Neurotrama2005，22，10： | 1 |
| 20 | The behavioral effectsof magnesium therapy on recovery of function following bilateral anterior medial cortex lesions in the rat显示文摘 | Hoane MR Knotts AA Akstulewicz SL | 2003 | Brain Res Bull2003，60，1： | 1 |
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