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| 1 | Simultaneous measurement of strain and temperature: graphical representation显示文摘Simultaneousmeasurementofstrainandtemperature:graphicalrepresentation⒇WJin(Dept.Electr.Eng.,HongKongPolytechnicUniv.)WCMichie... | W Jin (Dept. Electr. Eng., Hong Kong Polytechnic Univ. ) W C Michie, G Thursby, M Konstantaki, B Culshaw (Optoelectron. Div., Univ. of Strathclyde, Glasgow, UK) | 1997 | 大连理工大学学报1997，37，S2： | 3 |
| 2 | Clinical predictors of thiopurine-related adverse events in Crohn's disease显示文摘AIM: To determine the incidence and predictors of thiopurine-related adverse events. METHODS: Subjects with Crohn's disease who were followed in the Alberta Inflammatory Bowel Disease Consortium patient database registry were identified. Retrospective chart review was conducted between August 5th, 2010 and June 1st, 2012. We collected data on: age at diagnosis; sex; disease location and behaviour at time of prescribing thiopurine; perianal fistulising disease at or prior to thiopurine prescription; smoking status at time of thiopurine prescription, use of corticosteroid within 6 mo of diagnosis; dosage, age at onset, and cessation of 5-aminosalicyclic acid(5-ASA); anti-tumour necrosis factor medication exposure and intestinal resection before thiopurine prescription. The primary outcome of interest was the first adverse event that led to discontinuation of the first thiopurine medication used. Logistic regression models were used to associate clinical characteristics with outcomes after adjusting for potential confounders. Risk estimates were presented as odds ratios(OR) with 95% CI. Effect modification by age and sex were explored.RESULTS: Our cohort had a median follow-up duration of 5.8 years [interquartile range(IQR 25th-75th) 2.7-9.1]. Thiopurine therapy was discontinued in 31.3% of patients because of: hypersensitivity reactions(7.1%), acute pancreatitis(6.2%), gastrointestinal intolerance(5.4%), leucopenia(3.7%), hepatotoxicity(3.4%), infection(1.1%) and other reasons(4.3%). A higher incidence of thiopurine withdrawal was observed in patients over the age of 40(39.4%, P = 0.007). A sexby-age interaction(P = 0.04) was observed. Females older than 40 years of age had an increased risk of thiopurine discontinuation due to an adverse event(age above 40 vs age below 40, adjusted OR = 2.8; 95%CI: 1.4-5.6). In contrast, age did not influence thiopurine withdrawal in males(age above 40 vs below 40, adjusted OR = 0.9; 95%CI: 0.4-2.1). Other clinical variables(disease location and phenotype, perianal disease, smoking history, history of intestinal resection and prior 5-ASA or corticosteroid use) were not associated with an increased risk an adverse event leading to therapy cessation. CONCLUSION: Thiopurine withdrawal due to adverse events is commoner in women over the age of 40 at prescription. These findings need to be replicated in other cohorts. | Gordon W Moran Marie-France Dubeau Gilaad G Kaplan Hong Yang Bertus Eksteen Subrata Ghosh Remo Panaccione | 2015 | World Journal of Gastroenterology2015，21，25： | 2 |
| 3 | Simulation and experiment on SIW slot array antennas 显示文摘 | Yan L Hong W Hua G | 2004 | Microwave and Wireless Components Letters2004，14，9： | 1 |
| 4 | Takot subo cardiomyopathy (left ventricular ballooning syn drome) induced during dobutamine stress echocardio graphy显示文摘 | SILBERBAUER J HONG P LLOYD G W | 2008 | Eur J Echocardiogr2008，9，： | 1 |
| 5 | A novel all-fiber high velocity interferometer for any reflector显示文摘 | HONG G W JIA B WANG X | 2007 | Microwave and Optical Technology Letters2007，49，8： | 1 |
| 6 | A nanoliter-scale nucleic acid processor with parallel architecture显示文摘 | Hong J W Studer V Hang G | 2004 | Nature Biotechnology2004，22，： | 1 |
| 7 | Self Concept and Advertising Effectiveness:The Influence of Congruence,Conspicuousness and Response Mode显示文摘 | Hong JW Zinkhan G W | 1995 | Psychology and Marketing1995，，： | 1 |
| 8 | Analytical method for behaviour of a reinforced concrete flexural member at elevated temperatures 显示文摘 | KANG S W HONG S G | 2004 | Fire and Materials2004，28，24： | 1 |
| 9 | Effects of minimally invasive procedures for removal of intracranial hematoma on matrix metalloproteinase expression and blood-brain barrier permeability in perihematomal brain tissues显示文摘 | W u G Wang L Hong Z | 2011 | Neurol Res2011，33，3： | 1 |
| 10 | 查看详情显示文摘 | Yan L W Duan X R Ding X T Dong J Q Yang Q W Liu Y Zou X L Liu D Q Xuan W M Chen L Y Rao J Song X M Huang Y Mao W C Wang Q M Li Q Cao Z Li B Cao J Y Lei G J Zhang J H Li X D Chen W Cheng J Cui C H Cui Z Y Deng Z C Dong Y B Feng B B Gao Q D Han X Y Hong W Y | | 0，，： | 1 |
| 11 | Self concept and advertising effectiveness:A conceptual model of congruency,conspicuousness,and response mode显示文摘 | ZINKHAM G M HONG J W | 1991 | Advances in consumer research1991，18，： | 1 |
| 12 | An F-box gene linked to the self-incompatibility (S) locus of Antirrhinum is expressed specifically in pollen and tapetum显示文摘 | LAI Z MA W S H AN B LIANG L Z ZHANG Y S HONG G F XUE Y B | 2002 | Plant Molecular Biology2002，50，1： | 1 |
| 13 | Nitric oxide function and signaling in plant disease resistance 显示文摘 | Hong J K Yun B W Kang J G Raja M U Kwon E Sorhagen K Chu C C Wang Y Q Loake G J | 2008 | Journal of Experimental Botany2008，59，2： | 1 |
| 14 | Effect of 1- phenylsulfonyl]-3-(trans-4-methyl- cyclohexyl) urea( 14 ), a new synthetic sulfonylurea compound, on glucose metabolism in vivo and in vitro 显示文摘 | Wu G Z Hong G Zhang W P | 2009 | Rzneimittelforschung2009，59，11： | 1 |
| 15 | The known immunologically active components of astragalus account for only a small proportion of the immunological adjuvant activity when combined with conjugate vaccines显示文摘 | Hong F Xiao W Ragupathi G | 2007 | Planta Med2007，，3： | 1 |
| 16 | Preparation of spherical phosphor (Y,Gd)BO3:Eu by polymeric aerosol pyrolysis显示文摘 | JEOUNG B W HONG G Y YOO W T | 2004 | Electrochem Soc2004，151，10： | 1 |
| 17 | FSA-Based link assignment and routing in low-earth orbit satellite networks 显示文摘 | Hong S C Byoung W K Chang G L | 1998 | IEEE Transactions on Vehicular Technology1998，47，3： | 1 |
| 18 | Incidence,mechanism,predictors,and long-term prognosis of late stent malapposition after bare metal stent implantation显示文摘 | Hong M K Mintz G S Lee C W | 2004 | Circulation2004，109，5： | 1 |
| 19 | Basic concepts of DEMO and a design of a helium-cooled molten lithium blanket for a testing in ITER显示文摘 | Hong B G Lee D W Wang S J | 2007 | Fusion Engineering and Design2007，82，1524： | 1 |
| 20 | The Evaluation of Energy Consumption and CO2 Emission on Green Building Certification Apartments in Korea显示文摘 | Park J H Cha G W Hong W H | 2014 | Applied Mechanics&Materials2014，525，： | 1 |
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