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| 1 | Seasonal water storage change of the Yangtze River basin detected by GRACE显示文摘US-Germany co-sponsered satellite gravimetry mission GRACE (Gravity Recovery And Climate Experiment), launched in March 2002, has been producing monthly time series of Earth gravity models up to degree and order of 120. The GRACE mission consists of two identical satellites flying on an almost polar orbit with an altitude of about 300-500 km and satelite-to-satellite ranging of about 220 km. Thanks to the payloads of space-borne GPS receivers, accelerometers and high-precision K-band satelite-to-satellite ranging mesurements, GRACE gravity models are expected to achieve more than one order of magnitude of improvement over previous models at spatial scales of a few hundred kilometers or larger. Recovery of surface mass re-distribution based on GRACE’s time-varying gravity models is applied to studies in solid Earth geophysics, oceanography, climatology and geodesy. At secular time scales, GRACE is expected to provide valuable information on global ice changes, whose variations have profound influences on global climate, and in particular, on sea level changes. At seasonal time scales, GRACE is expected to reveal surface water changes with an ac- curacy of less than 1 cm, or ocean bottom pressure changes with an accuracy of less than 1 mbar (1 mbar =102 Pa). These surface mass redistribution measurements would impove our understanding of the global and regional mass and energy cycles that are critical to human life. Using 15 GRACE monthly gravity models covering the period from April 2002 to December 2003, this study compares seasonal water storage changes recovered from GRACE data and hydrology models at global and regional scales, with particular focus on the Yangtze River basin of China. Annual amplitude of 3.4 cm of equivalent water height change is found for the Yangtze River basin with maximum in Spring and Autumn, agreeing with two state-of-the-art hydrology models. The differences between GRACE re- sults and model predictions are less than 1-2 cm. We conclude that satellite gravimetry has huge potentials in monitering water storage changes in large river basins such as Yangtze. | HU Xiaogong1, CHEN Jianli1,2, ZHOU Yonghong1, HUANG Cheng1 & LIAO Xinhao1 1. Center for Astro-geodynamics Research, Shanghai Astronomical Observatory, National Astronomical Observatories, Shanghai 200030, China 2. Center for Space Research, University of Texas at Austin, 3925 W. Braker Lane, Suite 200, Austin, TX78750, USA | 2006 | Science China Earth Sciences2006，49，5： | 29 |
| 2 | Mycoplasma infections and different human carcinomas显示文摘AIM To explore relationships between human carcinomas and mycoplasma infection.METHODS Monoclonal antibody PD4, which specifically recognizes a distinct protein from mycoplasma hyorhinis, was used to detect mycoplasma infection in different paraffinembedded carcinoma tissues with immunohistochemistry. PCR was applied to amplify the mycoplasma DNA from the positive samples for confirming immunohistochemistry.RESULTS Fifty of 90 cases (56%) of gastric carcinoma were positive for mycoplasma hyorhinis. In other gastric diseases, the mycoplasma infection ratio was 28% (18/49) in chronic superficial gastritis, 30% (14/ 46) in gastric ulcer and 37% (18/ 49) in intestinal metaplasia. The difference is significant with gastric cancer (X2=12.06, P<0.05). In colon carcinoma, the mycoplasma infection ratio was 55.1% (32/58), but it was 20.9% (10/49) in adenomarous polyp (X2=13.46, P<0.005).Gastric and colon cancers with high differentiation had a higher mycoplasma infection ratio than those with low differentiation (P< 0.05). Mycoplasma infection in esophageal cancer, lung cancer, breast cancer and glioma was 50.9% (27/53), 52.6% (31/ 59), 39.7%(25/63) and 41% (38/91), respectively. The mycoplasma DNA was successfully amplified with the DNA extracted from the cancer tissues that were positive for mycoplasma infection (detected with antibody PD4).CONCLUSION There was high correlation between mycoplasma infection and different cancers, which suggests the possibility of an association between the two. The mechanism involved in oncogenesis by mycoplasma remains unknown. | Su Huang Ji You Li Jan Wu Lin Meng Cheng Chao Shou Beijing Institute for Cancer Research, Peking University School of Oncology, Beijing 100034. ChinaSu Huang, received B. A from Jiangxi Medical College of China in 1994. Now she is a graduate student pursuing a Ph. D degree at the Peking University School of Oncology. | 2001 | World Journal of Gastroenterology2001，7，2： | 18 |
| 3 | Quantum secret sharing between multiparty and multiparty with Bell states and Bell measurements显示文摘We present a quantum secret sharing scheme between multiparty (m members in Group 1) and multiparty (n members in Group 2), and analyze its security. This scheme takes EPR pairs in Bell states as quantum resources. In order to obtain the shared key, all members only need to perform Bell measurements, rather than perform any local unitary operation. The total efficiency in this scheme approaches 100% as the classical information exchanged is not necessary except for the eavesdropping checks. | SHI RunHua 1,2* , HUANG LiuSheng 1,3 , YANG Wei 1,3 & ZHONG Hong 2 1 National High Performance Computing Center at Hefei, Department of Computer Science and Technology, University of Science and Technology of China, Hefei, 230027, China 2 School of Computer Science and Technology, Anhui University, Hefei 230039, China 3 Suzhou Institute for Advanced Study, USTC, Suzhou 215123, China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，12： | 17 |
| 4 | Current progress in epigenetic research for hepato-carcinomagenesis显示文摘Hepatocellular carcinoma is the main type of primary liver cancer,and also one of the most malignant tumors.At present,the pathogenesis mechanisms of liver cancer are not entirely clear.It has been shown that inactivation of tumor suppressor genes and activation of oncogenes play a significant role in carcinogenesis,caused by the genetic and epigenetic aberrance.In the past,people generally thought that genetic mutation is a key event of tumor pathogenesis,and somatic mutation of tumor suppressor genes is in particular closely associated with oncogenesis.With deeper understanding of tumors in recent years,increasing evidence has shown that epigenetic silencing of those genes,as a result of aberrant hypermethylation of CpG islands in promoters and histone modification,is essential to carcinogenesis and metastasis.The term epigenetics refers to heritable changes in gene expression caused by regulation mechanisms,other than changes in the underlying DNA sequence.Specific epigenetic processes include DNA methylation,genome imprinting,chromotin remodeling,histone modification and microRNA regulations.This paper reviews recent epigenetics research progress in the hepatocellular carcinoma study,and tries to depict the relationships between hepatocellular carcinomagenesis and DNA methylation as well as microRNA regulation. | HUANG Jian National Human Genome Research Center at Shanghai-Ministry of Science and Technology to build a healthy and disease Ge-nomics Laboratory,Shanghai 201203,China | 2009 | Science China(Life Sciences)2009，52，1： | 9 |
| 5 | TOC changes in the process of thermal evolution of source rock and its controls显示文摘Through geological observation, simulation in laboratory and numerical modeling, the factors that control the changes in total organic content (TOC) of source rock have been studied. When the formula DTOC=(TOC0-TOC)/TOC0 (original organic carbon content in the rock) is used to measure the TOC (total organic carbon content) changes in the source rock through geological time, the degrees and directions of such changes are determined by losses and relative amounts both of organic and inorganic matter in the source rock. The DTOC equa-tion, which is used to calculate the loss rate in the process of maturation for the source rock, is therefore obtained by analyzing the mass balance relations. For a certain type of source rock with a certain maturation history, the changes of its TOC respond only to the rates of hydrocarbon generation and expulsion. In actual cases of geological entities, DTOC generally ranges from -0.05 to 0.2, while the calculated reconversion coefficient (k) for organic carbon content remains between 0.90 and 1.25. Only in an ideal situation where there are extremely high rates of hydrocarbon generation and expulsion can the DTOC value experience significant changes, with k reaching up to 2.5. It is concluded, therefore, that the cri-terion for carbonates source rock assessment, based on reconverting the TOC to the value of its original state, may have overestimated the course of the carbon-reduction, which is likely in many cases to make a poor source rock sound better. | ZHONG Ningning1, LU Shuangfang2, HUANG Zhilong1, ZHANG Yousheng1, XUE Haitao2 & PAN Changchun3 1. The Key Lab of Petroleum Accumulation Mechanism of State Educational Ministry at University of Petroleum, Beijing 102249, China 2. Exploration Geoscience Department of Daqing Petroleum Institute, Daqing 163000, China 3. Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China | 2004 | Science China Earth Sciences2004，47，z2： | 9 |
| 6 | The cessation and detoxification effect of tea filters on cigarette smoke显示文摘To treat tobacco addiction,a tea filter was developed and studied for smoking cessation.This work reports the smoking cessation effect of tea when it was used as a component of cigarette filters.In one trial it was found that after using the tea filters for 2 months,the volunteer smokers decreased their cigarette consumption by 56.5%,and 31.7% of them stopped smoking.This work identified a new method and material,tea filter and theanine,which inhibit tobacco and nicotine addiction and provide an effective strategy for treating tobacco addiction. | YAN JingQi1,2,DI XiaoJing1,4,LIU CaiYi3,ZHANG HuiMin3,HUANG XiouQin3,ZHANG JunJing1,2,ZHAO Yan5,ZHANG LongZe1,CHANG YanZhong4,LIANG YongLin2$,TAO Ran3 & ZHAO BaoLu1,21 State Key Laboratory of Brain and Cognitive Science,Institute of Biophysics,Chinese Academy of Sciences,Beijing 100101,China 2 Key Laboratory of Mental Health,Institute of Psychology,Chinese Academy of Sciences,Beijing 100101,China 3 Addiction Branch,Beijing Military Region General Hospital,Beijing 100700,China 4 Institute of Molecular Neurobiology,Hebei Normal University,Shijiazhuang 050016,China 5 Department of Food Sciences and Technology,Harbin Institute of Technology at Weihai,Weihai 264209,China | 2010 | Science China(Life Sciences)2010，53，5： | 8 |
| 7 | Development and application of genotyping technologies显示文摘With the completion of Human Genome Project,International HapMap Project and the publication of copy number variation in human genome,a great number of accurate,rapid,and cost-effective technologies for SNP analysis have been developed,promoting the research of the complex diseases.This article presents a review of widely used genotyping techniques,and the progress and prospect in the study of complex diseases in terms of the projects and achievements of Chinese National Human Genome Center at Shanghai(CHGCs). | SHI JinXiu,WANG Ying & HUANG Wei Shanghai-MOST Key Laboratory of Health and Disease Genomics,Chinese National Human Genome Center at Shanghai,Shanghai 201203,China | 2009 | Science China(Life Sciences)2009，52，1： | 6 |
| 8 | Synthesis of gallium borate nanowires显示文摘 | Ding X X Huang Z X Huang X T et at | 2004 | ] Cryst Growth2004，263，14： | 1 |
| 9 | Identification of tumorigenic retinal stem-like cells in human solid retinoblastomas显示文摘 | Zhong X U Y Peng F Huang B Lin J Zhang W et at | 2007 | Int J Cancer2007，121，10： | 1 |
| 10 | The expanded global registry of acute coronary events:baseline characteristics,management practices,and hospital outcomes of patients w ith acute coronary syndromes显示文摘 | Goodman SG Huang W Yan AT | 2009 | Am Heart J2009，158，2： | 1 |
| 11 | Growth Population and Industrialization and Urban Land Expansion of China 显示文摘 | Xiang Zheng - deng Jikun Huang Scott Rozelle el at | 2008 | Journal of Urhan Economics2008，63，1： | 1 |
| 12 | A model'based sound localization system and its application to robot navigation显示文摘 | Huang Jie Supaongprapa T Terakura I et at | 1999 | Robotics and Autonomous Systems1999，27，： | 1 |
| 13 | Effect of GnRH II and GnRH I on secretion of VEGF by eutopic and ectopic endometrial stromal cells of endometriosis patient显示文摘 | Huang F Liu Q Wang H et at | 2010 | Zhong Nan Da Xue Xue Bao Yi Xue Ban2010，35，： | 1 |
| 14 | Room-temperature Ultraviolet Nanowire Nanolasers 显示文摘 | Huang M H Mao S Feick H et at | 2001 | Science2001，292，5523： | 1 |
| 15 | The role of tanshinone IIA in the treatment of obesity through peroxisome proliferator-activated receptor gamma antagonism 显示文摘 | Gong Z Huang C Sheng X et at | 2009 | Endocrinology2009，150，： | 1 |
| 16 | Single strand conformation polymorphism analysis of androgen receptor gene mutations in patients with androgen insensitivity syndromes: application for d iagnosis, genetic counselling, and therapy显示文摘 | Hiort O Huang Q Sinnecker G H et at | 1993 | J Clin Endocrinol Metab1993，77，： | 1 |
| 17 | Imaging characteristics of neovascular pigment epithelial detachments and their response to anti-vascular endothelial growth factor therapy 显示文摘 | Punjabi as Huang J Rodriguez L Lyon AT Jampol LM Mirza RG | 2013 | Br J Ophthalmol2013，97，8： | 1 |
| 18 | The role of a mutant CCR5 allele in HIV-1 transmission and disease progression显示文摘 | Huang Y Paxton WA Wolinsky SM et at | 1996 | Nat Med1996，2，11： | 1 |
| 19 | The expanded Global Registry of Acute Coronary Events : baseline characteristics, management practices, and hospital outcomes of patients with acute coronary syndromes 显示文摘 | Goodman SG Huang W Yan AT | 2009 | Am Heart J2009，158，2： | 1 |
| 20 | Inhibition of growth and metastasis of orthotopic human prostate cancer in athymic mice by combination therapy with pegylated interferon alpha-2b and docetaxel显示文摘 | Huang SF Kim SJ Lee AT | 2002 | Cancer TES2002，62，20： | 1 |
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