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| 1 | Is colonic lavage a suitable alternative for left-sided colonic emergencies?显示文摘BACKGROUND The use of intra-operative colonic lavage(IOCL)with primary anastomosis remains controversial in the emergency left-sided large bowel pathologies,with alternatives including Hartmann’s procedure,manual decompression and subtotal colectomy.AIM To compare the peri-operative outcomes of IOCL to other procedures.METHODS Electronic databases were searched for articles employing IOCL from inception till July 13,2020.Odds ratio and weighted mean differences(WMD)were estimated for dichotomous and continuous outcomes respectively.Single-arm meta-analysis was conducted using DerSimonian and Laird random effects.RESULTS Of 28 studies were included in this meta-analysis,involving 1142 undergoing IOCL,and 634 other interventions.IOCL leads to comparable rates of wound infection when compared to Hartmann’s procedure,and anastomotic leak and wound infection when compared to manual decompression.There was a decreased length of hospital stay(WMD=-7.750;95%CI:-13.504 to-1.996;P=0.008)compared to manual decompression and an increased operating time.Single-arm meta-analysis found that overall mortality rates with IOCL was 4%(CI:0.03-0.05).Rates of anastomotic leak and wound infection were 3%(CI:0.02-0.04)and 12%(CI:0.09-0.16)respectively.CONCLUSION IOCL leads to similar rates of post-operative complications compared to other procedures.More extensive studies are needed to assess the outcomes of IOCL for emergency left-sided colonic surgeries. | Hui Yu Tham Wen Hui Lim Sneha Rajiv Jain Cheng Han Mg Snow Yunni Lin Jie Ling Xiao Fung Joon Foo Kar Yong Wong Choon Seng Chong | 2021 | World Journal of Gastrointestinal Surgery2021，13，4： | 3 |
| 2 | Improved survival in surgical stage Ⅰ patients with uterine papillary serious carcinoma (UPSC) treated with adjuvant platinum - based chemotherapy显示文摘 | Kelly MG Oinalley DM Hui P | 2005 | Gynecol Oncol2005，98，： | 1 |
| 3 | A double-blind, crossover assessment of the sedative and analgesic effects of intranasal dexmedetomidine显示文摘 | Yuen VM Irwin MG Hui TW | 2007 | Anesth Analg2007，105，2： | 1 |
| 4 | Improved survival in surgical stage I patients with uterine papillary serous carcinoma (UPSC) treated with adjuvant platinum-based chemotherapy显示文摘 | Kelly MG O'Malley DM Hui P | 2005 | Gynecol Onco12005，98，： | 1 |
| 5 | Optimal timing for the adm- inistration of intranasal dexmedetomidine for premedication in children 显示文摘 | Yuen VM Hui TW Irwin MG | 2010 | Anaesthesia2010，65，9： | 1 |
| 6 | CharaCterization of the 'deqi' response in acupuncture显示文摘 | Hui KK Nixon EE Vangel MG | 2007 | BMC Complement Altern Med2007，，7： | 1 |
| 7 | Improved survival in surgical stage I patients with uterine papillary serous carcinoma (UPSC) treated with adjuvant platinum-based chemotherapy显示文摘 | Kelly MG O'malley DM Hui P | 2005 | Gynecol Oncol2005，98，3： | 1 |
| 8 | A double-blind, crossover assessment of the sedative and analgesic effects of intranasal dexmedetomidine显示文摘 | Yuen VM Irwin MG Hui TW | 2007 | Anesth Analg2007，105，2： | 1 |
| 9 | A comparison of in- tranasal dexmedetomidine and oral midazolam for pre- medication in pediatric anesthesia:A double-blinded randomized controlled trial显示文摘 | Yuen VM Hui TW Irwin MG | 2008 | Anesth Analg2008，106，6： | 1 |
| 10 | A doublelind, crossover assessment of the sedative and analgesic effects ofintranasal dexmedetomidine 显示文摘 | Yuen VM Irwin MG Hui TW | 2007 | Anesth Analg2007，105，2： | 1 |
| 11 | Propofol effective concentra- tion 50 and its relationship to bispectralindex 显示文摘 | Irwin MG Hui TW Milne SE | 2002 | Anaesthesia2002，57，3： | 1 |
| 12 | Improved survival in surgical stage I patients with uterine papillary serous carcinoma (UPSC) treated with adjuvant platinum-based chemotherapy显示文摘 | Kelly MG O'Malley DM Hui P | 2005 | Gynecol Oncol2005，98，3： | 1 |
| 13 | A double-blind, cro- ssover assessment of the sedative and analgesic effects of intranasal dexmedetomidine显示文摘 | Yuen VM Irwin MG Hui TW | 2007 | Anesth Analg2007，105，2： | 1 |
| 14 | A comparison of intranasal dexmedetomidine and oral midazolam for premedication in pediatric anesthesia:A double-blinded randomized controlled trial显示文摘 | Yuen VM Hui TW Irwin MG | 2008 | Anesth Analg2008，106，6： | 1 |
| 15 | A comparison of in- tranasal dexmedetomidine and oral midazolam for premedi- cation in pediatric anesthesia: a double-blinded randomized controlled trial显示文摘 | Yuen VM Hui TW Irwin MG | 2008 | Anesth Analg2008，106，6： | 1 |
| 16 | A double-blind, crossover assessment of the sedative and analgesic effects of intranasal dexmedetomidine显示文摘 | Yuen VM Irwin MG Hui TW | 2007 | Anesth Analg2007，105，2： | 1 |
| 17 | A comparison of intranasal dexmedetomidine and oral midazolam for premedication in pediatric anesthesia:a double-blinded randomized controlled trial显示文摘 | Yuen VM Hui TW Irwin MG | 2008 | Anesth Analg2008，106，6： | 1 |
| 18 | Optimal timing for the administration of intranasal dexmedetomidine for premedication in children 显示文摘 | Yuen VM Hui TW Irwin MG | 2010 | Anaesthesia2010，65，9： | 1 |
| 19 | Optimal timing for the administration of intranasal dexmedetomidine for premedication in children显示文摘 | Yuen VM Hui TW Irwin MG | 2010 | Anaesthesia2010，65，9： | 1 |
| 20 | Improved survival in surgical stage I patients with uterine papillary serous carcinoma(UPSC)treated with adjuvant platinum-based chemotherapy显示文摘 | Kelly MG O'malley DM Hui P | 2005 | Gynecol Oncol2005，98，3： | 1 |
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