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88篇 您的检索式:作者名="IANNETTONI"
    题名 作者 年代 出处 被引量
1Relationship between HER-2 overexpression and brain metastasis in esophageal cancer patients显示文摘AIM:To study if HER-2 overexpression by locally advanced esophageal cancers increase the chance of brain metastasis following esophagectomy.METHODS:We retrospectively reviewed the medical records of esophageal cancer patients who underwent esophagectomy at University of Iowa Hospitals and Clinics between 2000 and 2010.Data analyzed consisted of demographic and clinical variables.The brain metastasis tissue was assayed for HER-2 overexpression utilizing the FDA approved DAKO Hercept Test.RESULTS:One hundred and forty two patients were reviewed.Median age was 64 years(36-86 years).Eighty eight patients(62%) received neoadjuvant chemoradiotherapy.Pathological complete and partial responses were achieved in 17(19%) and 71(81%) patients.Cancer relapsed in 43/142(30%) patients.The brain was the first site of relapse in 9/43 patients(21%,95% CI:10%-36%).HER-2 immunohistochemistry testing of the brain metastasis tissue showed that 5/9(56%) cases overexpressed HER-2(3+ staining).CONCLUSION:HER-2 overexpression might be associated with increased risk of brain metastasis in esophageal cancer patients following esophagectomy.Further studies will be required to validate this observation.Taher Abu Hejleh Barry R DeYoung Eric Engelman Jeremy M Deutsch Bridget Zimmerman Thorvardur R Halfdanarson Daniel J Berg Kalpaj R Parekh William R Lynch Mark D Iannettoni Sudershan Bhatia Gerald Clamon 2012World Journal of Gastrointestinal Oncology2012,4,5:5
2Evaluation of patients with pulmonary nodules: when is it lung cancer: ACCP evidence - based clinical practice guidelines (2nd edition) 显示文摘Gould MK Fletcher J Iannettoni MD 2007Chest2007,132,3:1
3Complications of esophageal resection and reconstruction显示文摘Parekh K Iannettoni MD 2007Semin Thorac Cardiovasc Surg2007,19,1:1
4The solitary pulmonary nodule显示文摘Tan BB Flaherty KR Kazerooni EA Iannettoni MD 2003Chest2003,123,:1
5Transhiatalesophagectomy : clinical experience and refinements 显示文摘Orringer MB Marshall B Iannettoni MD 1999AnnSurg1999,230,39:1
6Does the FDG uptake of primary non-small cell lung cancer predict prognosis? A work in progress显示文摘Sugawara Y Quint LE Iannettoni MD 1999Clin Positron Imaging1999,2,2:1
7Evaluation of patients with pulmonary nodules: when is it lung cancer ACCP evidence- based clinical practice guidelines ( 2nd edition) 显示文摘Gould MK Fletcher J Iannettoni MD 2007Chest2007,132,:1
8Complications of esophageal resection and reconstruction显示文摘Parekh K Iannettoni MD 2007Semin Thorac Cardiovasc Surg2007,19,:1
9Evaluation of patients with pulmonary nodules: when is it lung Cancer?: ACCP evidence based clinical practice guidelines (2nd edition) 显示文摘Gould MK Fletcher J Iannettoni MD 2007Chest2007,132,:1
10Squamous cell carcinoma of the esophagus:treat with how many modalities显示文摘Cheng S Iannettoni M Koshy M 2009Semin Oncol2009,36,6:1
11Evaluation of patients with pulmonary nodules:when is it lung cancer:ACCP evidence-based clinical practice guidelines(2nd edition)显示文摘Gould MK Fletcher J Iannettoni MD 0,,3:1
12Transhiatal esophagectomy: clinical experience and refinements 显示文摘Orringer M B Marshall B Iannettoni M D 1999Ann Surg1999,23,3:1
13Evaluation of patients with pulmonary nodules: when is it lung cancer? ACCP evidence-based clinical practice guidelines ( 2nd edition)显示文摘Gould MK Fletcher J Iannettoni MD 2007Chest2007,132,3:1
14Eliminating the cervical esophagogastric anastomotic leak with a side-to-side stapled anastomosis 显示文摘Orringer MB Marshall B Iannettoni MD 2000J Thorac Cardiovasc Surg2000,119,:1
15Evaluation of patients with pulmonary nodules:when is it lung cancer ACCP evidence-based clini- cal practice guidelines ( 2nd edition) 显示文摘Gould MK Fletcher J Iannettoni MD 2007Chest2007,132,3:1
16Origin of both coronary arteries from the pulmonary artery显示文摘Urcelay GE Iannettoni MD Ludomirsky A 1994Circulation1994,90,5:1
17Intrathoracic esophageal perforation 显示文摘Whyte RI Iannettoni Orringer MB 1995J Thorac Cardiovasc Surg1995,109,1:1
18Solitary pulmonary nodules in patients with extrapulmonary neoplasms显示文摘Quint LE Park CH Iannettoni MD 0,,01:1
19Eliminating the cervicalesophagogastric anastomotic leak with a side-to-side stapled anastomosis显示文摘Orringer MB Marshall B Iannettoni MD 2000J Thorac Cardiovasc Surg2000,119,2:1
20Catastrophic complicationsof the cervical esophagogastric anastomosis 显示文摘Iannettoni MD Whyte RI Orringer MB 1995J Thorac Cardiovasc Surg1995,110,5:1
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