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| 1 | Retrograde-viewing device improves adenoma detection rate in colonoscopies for surveillance and diagnostic workup显示文摘AIM:To determine which patients might benefit most from retrograde viewing during colonoscopy through subset analysis of randomized,controlled trial data.METHODS:The Third Eye Retroscope Randomized Clinical Evaluation(TERRACE) was a randomized,controlled,multicenter trial designed to evaluate the efficacy of a retrograde-viewing auxiliary imaging device that is used during colonoscopy to provide a second video image which allows viewing of areas on the proximal aspect of haustral folds and flexures that are difficult to see with the colonoscope's forward view.We performed a post-hoc analysis of the TERRACE data to determine whether certain subsets of the patient population would gain more benefit than others from use of the device.Subjects were patients scheduled for colonoscopy for screening,surveillance or diagnostic workup,and each underwent same-day tandem examinations with standard colonoscopy(SC) and Third Eye colonoscopy(TEC),randomized to SC followed by TEC or vice versa.RESULTS:Indication for colonoscopy was screening in 176/345 subjects(51.0%),surveillance after previous polypectomy in 87(25.2%) and diagnostic workup in 82(23.8%).In 4 subjects no indication was specified.Previously reported overall results had shown a net additional adenoma detection rate(ADR) with TEC of 23.2% compared to SC.Relative risk(RR) of missing adenomas with SC vs TEC as the initial procedure was 1.92(P = 0.029).Post-hoc subset analysis shows additional ADRs for TEC compared to SC were 4.4% for screening,35.7% for surveillance,55.4% for diagnostic and 40.7% for surveillance and diagnostic combined.The RR of missing adenomas with SC vs TEC was 1.11(P = 0.815) for screening,3.15(P = 0.014) for surveillance,8.64(P = 0.039) for diagnostic and 3.34(P = 0.003) for surveillance and diagnostic combined.Although a multivariate Poisson regression suggested gender as a possibly significant factor,subset analysis showed that the difference between genders was not statistically significant.Age,bowel prep quality and withdrawal time did not significantly affect the RR of missing adenomas with SC vs TEC.Mean sizes of adenomas detected with TEC and SC were similar at 0.59 cm and 0.56 cm,respectively(P = NS).CONCLUSION:TEC allows detection of significantly more adenomas compared to SC in patients undergoing surveillance or diagnostic workup,but not in screening patients(ClinicalTrials.gov Identifier:NCT01044732). | Peter D Siersema Amit Rastogi Anke M Leufkens Paul A Akerman Kassem Azzouzi Richard I Rothstein Frank P Vleggaar Alessandro Repici Giacomo Rando Patrick I Okolo Olivier Dewit Ana Ignjatovic Elizabeth Odstrcil James East Pierre H Deprez Brian P Saunders Anthony N Kalloo Bradley Creel Vikas Singh Anne Marie Lennon Daniel C DeMarco | 2012 | World Journal of Gastroenterology2012，18，26： | 6 |
| 2 | New biocomposite filler for reconstruction of bone tissue changed by osteoporosis显示文摘 | IGNJATOVIC N AJDUKOVIC Z USKOKOVIC D | 2005 | J Mater Sci Mater Med2005，16，7： | 1 |
| 3 | Pathogenicity of Australian strains of avian infectious bronchitis vi- rus显示文摘 | Ignjatovic J Ashton D F Reece R | 2002 | Comp Pathol2002，126，： | 1 |
| 4 | Optimising monitoring in the management of Crohn’s disease: A physician’s perspective显示文摘 | Pavol Papay Ana Ignjatovic Konstantinos Karmiris Heda Amarante Pal Milheller Brian Feagan Geert D’Haens Philippe Marteau Walter Reinisch Andreas Sturm Flavio Steinwurz Laurence Egan Julián Panés Edouard Louis Jean-Frédéric Colombel Remo Panaccione | 2013 | Journal of Crohn’s and Colitis2013，，： | 1 |
| 5 | Low-grade fibromyxoid sarcoma of the liver: A case report显示文摘BACKGROUND Low grade fibromyxoid sarcoma(LGFMS)is a rare and benign mesenchymal tumor with indolent course,most commonly found in young or middle-aged men.The majority of the LGFMSs are located in the trunk and deep soft tissue of the lower extremities.They appear as well circumscribed,although not encapsulated,which often leads to incomplete surgical resection.Despite their seemingly benign appearance,these tumors have aggressive behavior with high metastatic and recurrence rates.Accurate histopathologic examination of the specimen and its immunohistochemical analysis are mandatory for a precise diagnosis.CASE SUMMARY We report a case of a 38 year-old-man who presented with jaundice and upper abdominal discomfort.Multi-detector computed tomography and magnetic resonance imaging showed a large left liver tumor mass,extending to the hepatoduodenal ligament.Left hepatectomy was performed with resection and reconstruction of hepatic artery and preservation of middle hepatic vein.Histopathologic examination confirmed the tumor being a low-grade fibromyxoid sarcoma.Three and a half years after surgery,the patient died after being diagnosed with spine metastasis.CONCLUSION Due to poor response to all modalities of adjuvant treatment,we consider that the focus of treatment should be on surgery as the only option for curing the disease. | Vladimir Dugalic Igor I Ignjatovic Jelena Djokic Kovac Nikola Ilic Jelena Sopta Slavenko R Ostojic Dragan Vasin Marko D Bogdanovic Igor Dumic Tamara Milovanovic | 2021 | World Journal of Clinical Cases2021，9，1： | 1 |
| 6 | Flat colon polyps:what should rodiologists know?显示文摘 | Ignjatovic A Burling D Ilangovan R | 2010 | 12:958-9662010，12，： | 1 |
| 7 | Anatomoclinical significance of splenic artery anastomotic bridges显示文摘 | Ignjatovic D Stimec B Duric B | 2000 | Acta Chir Iugosl2000，47，12： | 1 |
| 8 | Radiation-induced degradation of hydroxyapatite/poly L-lactide composite biomaterial 显示文摘 | Suljovrujic E Ignjatovic N Uskokovic D | 2007 | Radiation Physics and Chemistry2007，76，4： | 1 |
| 9 | Ssr analysis for genetic structure and diversity determi-nation of maize local populations from former Yugoslavia territories显示文摘 | IGNJATOVIC'-MICIC'D DRINIC'S M NIKOLIC'A | | 0，，11： | 1 |
| 10 | Pathogenicity of Australian strains of avian infectious bronchitis virus 显示文摘 | Ignjatovic J Ashton D F ReeceR | 2002 | Journal of Comparative Pathology2002，126，： | 1 |
| 11 | Total intravenous anesthesia us- ing remifentanil and propoofl with midazolam conduction in laporoscopic surgery of the gallbladder 显示文摘 | Romic P Ignjatovic D Rankovic M | 2001 | Acta C hir Iugosl2001，48，1： | 1 |
| 12 | Morphologic characteristics of primary nonperforative intestinal blast injuries inrats their evolution to secondary perforations显示文摘 | Tatic′V Ignjatovic′D Jevtic′M | 1996 | J Trauma-Injury Inf Crit Care1996，40，： | 1 |
| 13 | Antioxidative capabilities of some organic acids and their co-pigments with malvin显示文摘 | Markovic J M D Ignjatovic L M | 2003 | J Electroanal Chem2003，553，： | 1 |
| 14 | Blast Injure from Explosive Munitions显示文摘 | CerNak I Savic J Ignjatovic D etal | 1999 | J Trauma1999，47，1： | 1 |
| 15 | Can the gastrocolic trunk of Henle serve as an anatomical landmark in laparoscopic right colectomy? A oostmortem anatomical study 显示文摘 | Ignjatovic D Spasojevic M Stimec B | 2010 | Am J Surg2010，199，2： | 1 |
| 16 | Modified Mainz pouch II (Sigma Rectum pouch) urinary diversion: 12 years experience显示文摘 | Ignjatovic I Basic D | 2007 | Acta Chir Iu- gosl2007，54，4： | 1 |
| 17 | Can the gastrocolic trunk of Henle serve as an anatomical landmark in laparoscopic right colectomy? A postmortem anatomical study 显示文摘 | Ignjatovic D Spasojevic M Stimec B | 2010 | Am J Surg2010，199，2： | 1 |
| 18 | Comparative analysis of sutured and stapled colorectal anastomoses 显示文摘 | Cuk V Atanasijevic T Ignjatovic D | 1994 | Vojnosanit Pregl1994，51，6： | 1 |
| 19 | Synthesis and application of hydroxyapatite/polylactide composite hiomaterial 显示文摘 | Ignjatovic N Uskokovic D | 2004 | Appl Surf Sci2004，238，14： | 1 |
| 20 | Gamma irradiation processing of hydroxyapatite/poly-L - lactide composite biomaterial 显示文摘 | SULJOVRUJIC E IGNJATOVIC N USKOKOVIC D | 2003 | Radiat Phys Chem2003，67，34： | 1 |
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