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| 1 | 青春期多囊卵巢综合征诊治共识显示文摘对于青春期女性的多囊卵巢综合征(PCOS),目前国内外尚无公认的统一诊断标准,且治疗方案的选择也不尽相同。为使国内各级妇产科医师更好地诊治和管理青春期PCOS患者,更新知识,并与国际接轨,国内该领域的专家在参考国外相关共识及指南后,结合我国的具体情况,编写了'青春期多囊卵巢综合征诊治共识',以改变临床医生对PCOS的传统认识,达到规范诊断和治疗青春期PCOS患者的目的。 | Reproductive Endocrinology Group,Chinese Maternal & Child Health Industry Association,National Association of Health Industry & Enterprise Management | 2016 | 生殖医学杂志2016，25，9： | 62 |
| 2 | Recent development in structural design and optimization显示文摘With the fast development of computational mechanics and the capacity as well as the speed of modern computers,simulation-based structural optimization has become an indispensable tool in the design process of competitive products.This paper presents a brief description of the current status of structural optimization by reviewing some significant progress made in the last decades.Potential research topics are also discussed.The entire literatures of the field are not covered due to the limitation of the length of paper.The scope of this review is limited and closely related to the authors' own research interests. | Xu Guo·Geng-Dong Cheng State Key Laboratory of Structural Analysis for Industrial Equipment,Department of Engineering Mechanics,Dalian University of Technology, Dalian 116023,China | 2010 | Acta Mechanica Sinica2010，26，6： | 42 |
| 3 | Permian Alkaline Granites in Central Inner Mongolia and Their Geodynamic Significance显示文摘Alkaline granites (Rb-Sr ages 276-286 Ma)occurring in the Bayan Ul-East Ujimqin belt at the southern margin of the Siberian plate originated in a tensional tectonic environment about 60 Ma earlier than the Late Devonian to Early Carboniferous collision between the Siberian and Sino-Korean plates. They belong to post-orogenic A-type granites and may be used as an indicator of the end of the orogeny. At the northern margin of the Sino-Korean plate, however, only late-orogenic calc-alkaline granites occurred during the late Caboniferous-Permian, and alkaline syenites did not appear until the Late Triassic. The asymmetric magmatism at the margins of the two neighbouring plates might be controlled by the differences in size and mass of the two plates. | Hong Dawei, Huang Huaizeng, Lithosphere Research Center, Chinese Academy of Geological Sciences, BeijingXiao Yijun, Institute of Geology, Chinese Academy of Geological Sciences, BeijingXu Haiming,Institute of Mineral Deposits, Chinese Academy of Geological Sciences, Beijingand Jin M anyuanTianjin Geological Academy, Ministry of Metallurgical Industry, Tianjin Fei Zhenbi | 1995 | Acta Geologica Sinica(English Edition)1995，69，1： | 40 |
| 4 | 2005年全国治超工作要点显示文摘 | Issued by Ministry of Communications of the People′s Republic of China,T he Ministry of Public Security of the People′s Republic of China,National Development and Reform Comm ission,the Ministry of Propaganda of the CPC Central Committee,General Administration of Qu ality Supervision Inspection and Quarantine of the PRC,State Administration of Work Safety,State Administration for Industry & Commerce,China Legislative | 2005 | 交通标准化2005，，5： | 34 |
| 5 | Modelling of multi-bodies in close proximity under water waves——Fluid resonance in narrow gaps显示文摘Viscous fluid model and potential flow model with and without artificial damping force(f=-μV,μ the damping coefficient and V the local averaging flow velocity) are employed in this work to investigate the phenomenon of fluid resonance in narrow gaps between multi-bodies in close proximity under water waves.The numerical results are compared with experimental data available in the literature.The comparison demonstrates that both the viscous fluid model and the potential flow model are able to predict the resonant frequency reasonably well.However the conventional potential flow model(without artificial damping term) significantly over-predicts the wave height in narrow gaps around the resonant frequency.In order to calibrate the appropriate damping coefficient used for the potential model and make it work as well as the viscous fluid model in predicting the resonant wave height in narrow gaps but with little computational efforts,the dependence of damping coefficient μ on the body geometric dimensions is examined considering the parameters of gap width Bg,body draft D,body breadth ratio Br and body number n(n = 2,3),where Br = BB/BA for the case of two bodies(Body A and Body B) with different breadths of BA and BB,respectively.It was confirmed that the damping coefficient used for the potential flow model is not sensitive to the geometric dimensions and spatial arrangement.It was found that μ∈ [0.4,0.5] may guarantee the variation of Hg/H0 with kh to be generally in good agreement with the experimental data and the results of viscous fluid model,where Hg is the excited wave height in narrow gaps under various dimensionless incident wave frequencies kh,H0 is the incident wave height,k = 2π/L is the wave number and h is the water depth. | LU Lin1,2,TENG Bin3,CHENG Liang 4,SUN Liang5 & CHEN XiaoBo6 1 Center for Deepwater Engineering,Dalian University of Technology,Dalian 116024,China 2 State Key Laboratory of Structural Analysis for Industrial Equipment,Dalian University of Technology,Dalian 116024,China 3 State Key Laboratory of Coastal and Offshore Engineering,Dalian University of Technology,Dalian 116024,China 4 School of Civil and Resource Engineering,The University of Western Australia,Crawly 6003,Australia 5 Centre for Offshore Research and Engineering,Department of Civil Engineering,National University of Singapore,117576,Singapore 6 Research Department,Bureau Veritas,Neuilly-Sur-Seine,92570,France | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，1： | 29 |
| 6 | A SELF-ADAPTIVE TRUST REGION ALGORITHM显示文摘In this paper we propose a self-adaptive trust region algorithm.The trust region radius is updated at a varable rate according to the ratio between the actual reduction and the predicted reduction of the objective function,rather than by simply enlarging or reducing the original trust region radius at a constant rate.We show that this new algorithm preserves the strong convergence property of traditional trust region methods.Numerical results are also presented. | Long Hei (Institute of Computational Mathematics and Scientific/Engineering Computing, Academy ofMathematics and Systems Sciences, Chinese Academy of Sciences, Beijing 100080, China)(Department of Industrial Engineering and Management Sciences Northwestern University C2SO,2145 Sheridan Road Evanston, Illinois 60208, USA) | 2003 | Journal of Computational Mathematics2003，21，2： | 29 |
| 7 | An analysis on the evolvement processes of lake eutrophication and their characteristics of the typical lakes in the middle and lower reaches of Yangtze River显示文摘According to the study on the aquatic environment of the typical lakes in the middle and lower reaches of Yangtze River, lake eutrophication is a process in which the lake ecosystem degenerates, resulting in the deterioration of the water quality due to the enrichment of the nutrients. Moreover, the succession of lake ecosystem and change of water quality both couple well with the evolvement of tro- phic state. Then the conceptual model is mentioned and ten lake states are classified. Based on these, the authors analyzed the eutrophication processes of the typical lakes in the middle and lower reaches of Yangtze River. The large lakes with taking in - send- ing out water typical of Poyang Lake evolve from State 1 before the 1980s into State 2 after the 1980s, the large and medium lakes typical of Taihu Lake evolve from State 1-2 in the 1960s into State 8 in the 1980s then into State 9 in the 1990s, the medium and small shallow lakes typical of Honghu Lake evolve from State 1 in the 1960s into State 2 after the 1980s and the small city (suburban) lakes typical of Donghu Lake evolve from State 2 in the 1960s into State 9 after the 1970s. Further, the 1980s is the key con- version period of the lakes of various types typical of Poyang Lake, Honghu Lake and Taihu Lake con- verting into mesotrophic state, the 1990s is that of Taihu Lake into eutrophic state and the 1970s is thatof the small city (suburban) lakes typical of Donghu Lake into eutrophic state. The series of nutrient evolvement of different typical lakes are similar, but the processes are not synchronous, which is related to the various human and natural driving mechanisms in lake basins. | CHENG Xiaoying1,2,3 & LI Shijie1 1. Nanjing Institute of Geography & Limnology, Chinese Academy of Sciences, Nanjing 210008, China 2. The Key Laboratory of Industrial Biotechnology, Ministry of Educa- tion, Southern Yangtze University, Wuxi 214036, China 3. School of Biotechnology, Southern Yangtze University, Wuxi 214036, China | 2006 | Chinese Science Bulletin2006，51，13： | 26 |
| 8 | Influence of Different Extraction and Purification Methods on Astragalus Polysaccharides and Pharmacological Evaluation显示文摘Objective To clarify the influence on component and pharmacological action of Astragalus polysaccharides(APS) as complementary therapeutic agents prepared by different extraction and purification techniques.Methods Components of APS prepared by different extraction and purification techniques were analyzed,and these APS were used for synergy and attenuation of chemotherapy,radiotherapy treatment with H22 liver cancer and Lewis lung cancer of tumor-bearing mice,and also used for the regulation of immune function to immunosuppression mice.Results Experimental data were analyzed by means of statistical method to get pharmaco-result:A3(extracted by microwave assistance and purified by membrane separation)>A4(extracted by refluxing and purified by membrane separation)>A1(extracted by refluxing and no purification)≈A2(extracted by microwave assistance and no purification).There were no significant differences on pharmacodynamic action between A1 and A2.However,compared with A1 and A2,it was worth noting that A3 and A4 exhibited good pharmacodynamic action.Then A3-in and A4-in,the samples in dialyzer after dialysis,were separated and purified to get homogeneous APS,which were the principal constituents of APS in dialyzer,with the molecular weight(Mw) of 7669 and 14142 determined by HPGPC,respectively.The average Mw of APS outside of the dialyzer,A3-out was 3102 and A4-out 3256,which were the main compositions of A3 and A4,accounted for 79.63% and 53.92%,respectively.Conclusion APS with Mw about 5000 Da exhibit better antitumor effect and immunological activity.Refluxing,microwave assistance extractions,and membrane enrichment techniques bring different cases on Mw distribution,components and pharmacodynamic action,and obviously exhibit relationship among component,Mw distribution,and pharmacological action. | YANG Yi-fang1,FENG Jing-qian1,XU Hai-yan1,PENG Dan-ming2,HU Jian-ping2 1.Shanghai Institute of Pharmaceutical Industry,Shanghai 200040,China 2.Jiangxi Provincial Academy of Traditional Chinese Medicine,Nanchang 330077,China | 2010 | Chinese Herbal Medicines2010，2，1： | 24 |
| 9 | AtHsfA2 modulates expression of stress responsive genes and enhances tolerance to heat and oxidative stress in Arabidopsis显示文摘There is increasing evidence for considerable interlinking between the responses to heat stress and oxidative stress, and recent researches suggest heat shock transcription factors (Hsfs) play an important role in linking heat shock with oxidative stress signals. In this paper, we present evidence that AtHsfA2 modulated expression of stress responsive genes and enhanced tolerance to heat and oxidative stress in Arabidopsis. Using Northern blot and quantitative RT-PCR analysis, we demonstrated that the expression of AtHsfA2 was induced by not only HS but also oxidative stress. By functional analysis of AtHsfA2 knockout mutants and AtHsfA2 overexpressing transgenic plants, we also demonstrated that the mutants displayed reduced the basal and acquired thermotolerance as well as oxidative stress tolerance but the overexpression lines displayed increased tolerance to these stress. The phenotypes correlated with the expres-sion of some Hsps and APX1, ion leakage, H2O2 level and degree of oxidative injuries. These results showed that, by modulated expression of stress responsive genes, AtHsfA2 enhanced tolerance to heat and oxidative stress in Arabidopsis. So we suggest that AtHsfA2 plays an im-portant role in linking heat shock with oxidative stress signals. | LI Chunguang1,2, CHEN Qijun1, GAO Xinqi1,3, QI Bishu1, CHEN Naizhi1, XU Shouming1, CHEN Jia1 & WANG Xuechen1 1. State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing 100094, China 2. Department of Industry Engineering, Zhengzhou Institute of Aeronautic Industry Management, Zhengzhou 450015, China 3. College of Life Science, Qufu Normal University, Qufu Shandong 273165, China | 2005 | Science China(Life Sciences)2005，48，6： | 23 |
| 10 | Numerical simulations of self-propelled swimming of 3D bionic fish school显示文摘Numerical simulations of self-propelled swimming of a three dimensional bionic fish and fish school in a viscous fluid are carried out. This is done with the assistance of a parallel software package produced for 3D moving boundary problems. This computational fluid dynamics package combines the adaptive multi-grid finite volume method, the immersed boundary method and VOF (volume of fluid) method. By using the package results of the self-propelled swimming of a 3D bionic fish and fish school in a vis- cous fluid are obtained. With comparison to the existing experimental measurements of living fishes, the predicted structure of vortical wakes is in good agreement with the measurements. | WU ChuiJie1 & WANG Liang2 1 State Key Laboratory of Structural Analysis for Industrial Equipment, Dalian University of Technology, Dalian 116024, China 2 Research Center for Fluid Dynamics, People’s Liberation Army University of Science and Technology, Nanjing 211101, China | 2009 | Science China(Technological Sciences)2009，52，3： | 23 |
| 11 | Glutamine synthetase as an early marker for hepatocellular carcinoma based on proteomic analysis of resected smal hepatocel ular carcinomas显示文摘BACKGROUND:Hepatocellular carcinoma(HCC)is a highly malignant tumor with a poor prognosis.Because small HCCs possess most of the characteristics of early HCC,we investigated small HCCs to screen potential biomarkers for early diagnosis.METHODS:Proteins were extracted from 10 sets of paired tissue samples from HBV-infected small-HCC patients.The extracted proteins were well resolved by two-dimensional electrophoresis.These HCC-associated proteins were then identified by MALDI-TOF/TOF MS following image analysis.Western blotting and immunohistochemistry were used to assess glutamine synthetase(GS)and phenazine biosynthesislike domain-containing protein(PBLD)expression in liver tissue.Enzyme-linked immunosorbent assays in 152 serum samples(from 49 healthy donors,24 patients with liver cirrhosis,and 79 with HCC)were used to further assess the significance of GS clinically.RESULTS:Fifteen up-regulated and three down-regulated proteins were identified.Western blotting confirmed GS overexpression and decreased PBLD expression in liver tissue.Immunohistochemistry showed that GS was expressed in 70.0%(84/120)of HCCs and 35.8%(43/120)of nontumor tissues;PBLD was expressed in 74.2%(89/120) of nontumor tissues and 40.8%(49/120)of HCCs.The Chi-square test showed significant expression differences between HCCs and adjacent tissues.Consistent with this,serum GS levels in HCC patients were significantly higher than those in liver cirrhosis patients and healthy donors,while the latter two groups were also significantly different.In addition, a diagnostic cutoff value of 2.6 mg/ml was used for GS;it was elevated in 19(76.0%)of 25 HCC patients with AFP≤20 ng/ml and 47(88.7%)of 53 HCC patients with AFP≤200 ng/ml.CONCLUSION:GS and PBLD are abnormally expressed in most HCCs.GS may be a novel serum marker for early HCC, especially for those patients with low AFP levels(≤200 ng/ml). | Jiang Long,Zhen-Wei Lang,Hua-Guang Wang,Tai-Ling Wang,Bao-En Wang and Si-Qi Liu Liver Research Center,Beijing Friendship Hospital, Capital Medical University,Beijing 100050,China Department of Hepatology,Department of Pathology, Beijing Youan Hospital,Capital Medical University,Beijing 100069,China Department of Pharmaceutical Affairs,Beijing Chaoyang Hospital,Capital Medical University,Beijing 100020,China Department of Pathology,China-Japan Friendship Hospital,Beijing 100029,China Beijing Genomics Institute,Chinese Academy of Science,Beijing Airport Industrial Zone B-6,Shunyi,Beijing 101300,China | 2010 | Hepatobiliary & Pancreatic Diseases International2010，9，3： | 21 |
| 12 | Quantum secure direct communication with cluster states显示文摘A quantum secure direct communication protocol with cluster states is proposed.Compared with the deterministic secure quantum communication protocol with the cluster state proposed by Yuan and Song(Int.J.Quant.Inform.,2009,7:689),this protocol can achieve higher intrinsic efficiency by using two-step transmission.The implementation of this protocol is also discussed. | CAO WeiFeng 1,YANG YuGuang 3,4,5* & WEN QiaoYan 2 1 College of Electric and Information Engineering,Zhengzhou University of Light Industry,Zhengzhou 450002,China 2 State Key Laboratory of Networking and Switching Technology,Beijing University of Posts and Telecommunications,Beijing 100876,China 3 College of Computer Science and Technology,Beijing University of Technology,Beijing 100124,China 4 State Key Laboratory of Integrated Services Network,Xidian University,Xi’an 710071,China 5 State key Laboratory of Information Security Gradute University of Chinese Academy of Sciences,Beijing 100049,China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，7： | 20 |
| 13 | 中国塑料管道市场分析报告——钢增强塑料管道市场前景显示文摘介绍了近几年国内外塑料管道市场发展现状及趋势;同时分析了国内管道行业的发展特点;提出了我国塑料管道行业目前存在的主要问题;对应用领域塑料管道产品的生产和应用情况进行了阐述;分析了钢增强塑料管道现有技术水平和良好的市场前景。 | (Beijing Plastic Industry Association,Beijing 100000,China) | 2011 | 塑料工业2011，39，11： | 20 |
| 14 | 中国急需实施重组纸业的国家战略——对中国纸业发展战略的初步思考显示文摘调查研究阐述了我国经济发展对纸的需求可能所呈现的加速发展的态势;在国内环保标准和国际竞争的双重挑战面前,中国纸业如不能立即进行发展战略的根本转变,可能面临消亡,而给国民经济带来难以承受的损失;论述了中国纸业发展战略的指导思想,应是从零开始,一步到位,用具有前瞻性的国际现代化标准重塑造纸业:立即向以木为主、林纸一体化方向开始根本转变,立即着手组建若干林纸一体化的巨型公司,使中国纸业最有希望成为在世界上较快取得战略优势地位的产业之一。并提出了中国纸业发展的战略目标。 | The Research Group of the Development Strategy for China′s Paper Industry | 1999 | 中华纸业1999，20，2： | 18 |
| 15 | 中国光伏发电的技术现状及展望显示文摘介绍了中国光伏发电的技术现状及发展前景,包括太阳能资源,技术研发现状,工业化运作及景展望等方面内容。 | Chinese Renewable Energy Industries Association | 2002 | 可再生能源2002，20，3： | 16 |
| 16 | Mechanism of calcium mitigating membrane fouling in submerged membrane bioreactors显示文摘Two parallel membrane bioreactors (MBRs) were operated under different calcium dosages (168.5, 27 mg/L) to gain a better understanding of the mechanism of retarding membrane fouling by adding calcium. The results showed that the particle size of sludge flocs increased and the particle size distribution tended to be narrow at the optimum dosage (168.5 mg/L). Calcium was effective in decreasing loosely bound extracellular polymeric substances (LB-EPS) in microbial flocs and soluble microbial products (SMP) in the supernatant at the dosage of 168.5 mg/L by strengthening the neutralization and bridging of EPS with flocs. Furthermore, the amount of CODS and CODC decreased in both the mixed liquor and the fouling cake layer on the membrane surface. In order to compare the filtration characteristics of cake layers from the MBRs with the two calcium dosages, the specific cake resistance and the compressibility coefficient were measured. The specific cake resistance from the MBR with optimum dosage (168.5 mg/L) was distinctly lower than that with low dosage (27 mg/L). The compressibility coefficient of the cake layers under two dosages were respectively attained as 0.65, 0.91. Scanning electron microscopy (SEM) and three-dimensional confocal scanning laser microscope analysis (CLSM) images were utilized to observe the gel layer directly. | ZHANG Hanmin, XIA Jie, YANG Yang, WANG Zixing, YANG FenglinKey Laboratory of Industrial Ecology and Environmental Engineering, MOE, School of Environmental and Biological Science and Technology, Dalian University of Technology, Dalian 116024, China. | 2009 | Journal of Environmental Sciences2009，21，8： | 15 |
| 17 | Chemopreventive Effects of Black Tea Polyphenols in Mouse Skin Model of Carcinogenesis显示文摘In the present investigations, the antitumorigenic effect of black tea polyphenols (BTP) in twcrstage mouse skin model of carcinogenesis was studied. The animals were initiated with a single 'subcarcinogenic' topical dose (52 μg/200 μl acetone ) of 7, 12-dimethylbenzanthracene (DMBA). To evaluate the anti-tumour initiating activity, BTP was topically applied twice a week for three weeks prior to DMBA application, followed by topical treatment with 12-o-tetradecanoyl phorbol-13-acetate (TPA) (5 μg/200 μl acetone, 2x/wk. ) as promoter. For evaluation of antitumor promoting activity, BTP was applied prior to each treatment of TPA. BTP application showed marked inhibitory effect as antitumour initiator as well as antitumour promoter in mouse skin medel of two-stage carcinogenesis. Since initiation involves genetic pathway and tumour promotion involves epigenetic pathway, it seems that BTP exerts its antitumorigenic effect by altering both genetic and epigenetic | SEEMA JAVED N. K. MEHROTRA AND YOGESHWER SHUKLA(Laboratory of Environmental Chrcinogenesis, Industrial Toxicology Research Centre, M. G. Marg, P. O. Box 80,Lucknow - 226001, India) | 1998 | Biomedical and Environmental Sciences1998，11，4： | 15 |
| 18 | Target selection and transfer trajectories design for exploring asteroid mission显示文摘Technique of target selection and profiles of transfer trajectory for Chinese asteroid exploring mission are studied systemically.A complete set of approaches to selecting mission targets and designing the transfer trajectory is proposed.First,when selecting a target for mission,some factors regarded as the scientific motivations are discussed.Then,when analyzing the accessibility of targets,instead of the classical strategy,the multiple gravity-assist strategy is provided.The suitable and possible targets,taking into account scientific value and technically feasible,are obtained via selection and estimation.When designing the transfer trajectory for exploring asteroid mission,an approach to selecting gravity-assist celestial body is proposed.Finally,according to the mission constraints,the trajectory profile with 2-years △V-EGA for exploring asteroid is presented.Through analyzing the trajectory profile,unexpected result that the trajectory would pass by two main-belts asteroids is found.So,the original proposal is extended to the multiple flybys mission.It adds the scientific return for asteroid mission. | CUI PingYuan1,QIAO Dong1,CUI HuTao2 & LUAN EnJie3 1 School of Aerospace Engineering,Beijing Institute of Technology,Beijing 100081,China 2 Harbin Institute of Technology,Harbin 150001,China 3 National Defense Science and Industry Bureau,Beijing 100048,China | 2010 | Science China(Technological Sciences)2010，53，4： | 15 |
| 19 | 植物中有机硒含量的测定显示文摘对有机硒和无机硒的测定进行了探讨,利用压榨提取无机硒,用荧光二阶导数法进行硒的定量测定,通过标准添加法对提取率进行了测定,回收率为93.2%~98.4%,变异系数为1.86. | Qin Fang(Centre Research and Design Institute,Wuxi University of Light Industry,Wuxi,214036) | 1998 | 无锡轻工大学学报(食品与生物技术)1998，17，4： | 15 |
| 20 | Orogenic and Anorogenic Granitoids in the Altay Mountains of Xinjiang and Their Discrimination Criteria显示文摘On the basis of field geological studies of the granotoids in the region, mineralogical, petrological, geochemical(including stable isotope geochemical) and isotopic geochronological investigations were carried out on selected representative granitic bodies of various types. The authors have concluded that, apart from the bodies of the orogenic granitoid series, there also exist intrusions of the anorogenic granitoid series in the region. The intrusives of the two series were formed not only in different ages and tectonic environments, but also were derived from different sources of materials. Moreover, they are associated with different mineralizations, belonging to different minerologenetic series(Cheng et al., 1983). They show distinctly a series of discriminative criteria. The problems under discussion in the present paper are of important theoretical and practical significance in the studies of granites of the orogenic belt, particularly the studies of the genesis and related metallogeny of the granites of the region. | Zou Tianren Institute of Mineral Deposits, Chinese Academy of Geological Sciences, Beijing Chao Huizhi and Wu Baiqing Xinjiang Institute of Geology, Ministry of Metallurgical Industry Urumqi, Xinjiang Jiang Minxi | 1989 | Acta Geologica Sinica(English Edition)1989，63，1： | 14 |
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