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421篇 您的检索式:作者名="Izumo"
    题名 作者 年代 出处 被引量
1窄谱成像支气管镜对评估中央型肺癌浸润范围及制定治疗方案的价值显示文摘目的:评价窄谱成像( NBI)支气管镜对评估中央型肺癌浸润范围及制定治疗方案的价值。方法使用日本奥林巴斯公司的EVIS LUCERA光谱支气管镜,对2012年6月至2014年6月上海市第十人民医院符合入选标准的患者进行白光支气管镜( WLB)和NBI检查,统计并比较两种方法镜下肿瘤浸润范围、阳性表现和病理学结果。结果共196例患者入选,男152例,女44例,年龄(58±10)岁。分析确诊中央型肺癌的168例患者中,NBI 发现22例(13.1%)的肺癌浸润范围比WLB更广( NBI下浸润比WLB下>1 cm),其中19例(占肺癌患者的11.3%)改变治疗方案,包括改变手术方式14例,终止手术5例。多因素回归分析显示,病灶≥30 mm和病理类型为鳞癌为2个独立的预测因素,此类患者使用NBI评估肿瘤浸润范围较WLB更广的比例更高( OR=3.13,95% CI:1.06~9.21, P=0.038;OR=4.68,95% CI:1.02~21.58, P=0.048);NBI和WLB诊断肺癌敏感度、特异度、阳性预测值、阴性预测值分别为88.2%、83.3%、98.1%、41.7%和80.3%、55.6%、94.7%、22.2%。结论临床上使用NBI利于早期中央型肺癌的诊断,便于更准确的判断肺癌的浸润范围,帮助临床医师制定最佳的治疗方案。李明 Takehiro Izumo 张国良 彭爱梅 王昌惠 2014中华医学杂志2014,94,44:3
2Cytoplasm rescues an arrhythmic mutant on the circadian rhythm of mating reactivity in Parameciun bursaria显示文摘Miwa I Izumo T Sonoda T 1996J Euk Microbiol1996,43,:2
3Hemodynamic shear stress and its role in atherosclerosis 显示文摘Malek AM Alper SL Izumo S 1999JAMA1999,282,:1
4Apoptosis: basic mechanisms and implications for cardiovascular disease显示文摘Haunstetter A Izumo S 1998Circ Res1998,82,11:1
5Hemodynamic shear stress and its role in atherosclerosis显示文摘Malek AM Alper SL Izumo S 1999JAMA1999,282,21:1
6Phosphate provides an extracelllular signal that drives nuclear export of Runx2/Cbfa1 显示文摘Fujita T Izumo N Fukuyama T 2001Biochem Biophys Res Commun2001,280,1:1
7The role of the western Arabian Sea upwelling in Indian monsoon rainfall variability显示文摘Izumo T Montegut C B Luo J J 2008J Climate2008,21,:1
8Calcineurin-the missing link in cardiac hypertrophy显示文摘Izumo S Aoki H 1998J Nat Meal1998,4,:1
9GATA4 is adosage-sensitive regulator of cardiac morphogenesis显示文摘Pu WT Ishiwata T Juraszek AL Ma Q Izumo S 2004Dev Biol2004,275,1:1
10Toward antiapotosis as a new treatment modality显示文摘Haunstetter A Izumo S 2000Circ Res2000,86,4:1
11Role of the insulin-like growth factor 1 (IGF1) / phosphoinositide3-kinase (PI3K) pathway mediating physiological cardiac hypertrophy 显示文摘McMullen JR Izumo S 2006Novartis Found Syrup2006,274,:1
12Hemodynamic shear stress and its role in atherosclerosis显示文摘Malek A M Alper S L Izumo S 1999JAMA1999,282,21:1
13Hemodynamic shear stress and its role in atherosclerosis 显示文摘Malek AM Alper SL Izumo S 1999JAMA1999,282,21:1
14Hemodynamic shear stress and its role in atherosclerosis 显示文摘 Alper S L Izumo S 1999JAMA1999,282,:1
15Csx: A murine homeobox-containing gene specifically expressed in the developing heart显示文摘 IZUMO S 1993Proc Natl Acad Sci USA1993,90,:1
16Corticosteroid- loading PLA PLGA - nanospheres 显示文摘Izumo N IshiharaT MizushimaY 2006Nippon Rinsho2006,64,2:1
17The cellular and molecular response of cardiac myocyte to mechanical stress显示文摘Sadoshima J Izumo S 1997Annu Rev Physiol1997,59,3:1
18Apoptosis and heart failure:A critical review of the literature显示文摘Kang PM Izumo S 2000Circ Res2000,86,11:1
19Toward antipoptosis as a newtreatment modality显示文摘Haunstetter A Izumo S 2000Circ Res2000,86,4:1
20Apoptosis: basic mechanisms and implications for cardiovascular disease显示文摘Haunstetter A Izumo S 1998Circ Res1998,82,11:1
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