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| 1 | Effects of cellulase and xylanase enzymes mixed with increasing doses of Salix babylonica extract on in vitro rumen gas production kinetics of a mixture of corn silage with concentrate显示文摘An in vitro gas production(GP) technique was used to investigate the effects of combining different doses of Salix babylonica extract(SB) with exogenous fibrolytic enzymes(EZ) based on xylanase(X) and cellulase(C), or their mixture(XC; 1:1 v/v) on in vitro fermentation characteristics of a total mixed ration of corn silage and concentrate mixture(50:50, w/w) as substrate. Four levels of SB(0, 0.6, 1.2 and 1.8 m L g–1 dry matter(DM)) and four supplemental styles of EZ(1 μL g–1 DM; control(no enzymes), X, C and XC(1:1, v/v) were used in a 4×4 factorial arrangement. In vitro GP(m L g–1 DM) were recorded at 2, 4, 6, 8, 10, 12, 24, 36, 48 and 72 h of incubation. After 72 h, the incubation process was stopped and supernatant p H was determined, and then filtered to determine dry matter degradability(DMD). Fermentation parameters, such as the 24 h gas yield(GY24), in vitro organic matter digestibility(OMD), metabolizable energy(ME), short chain fatty acid concentrations(SCFA), and microbial crude protein production(MCP) were also estimated. Results indicated that there was a SB?EZ interaction(P<0.0001) for the asymptotic gas production(b), the rate of gas production(c), GP from 6 to 72 h, GP2(P=0.0095), and GP4(P=0.02). The SB and different combination of enzymes supplementation influenced(P<0.001) in vitro GP parameters after 12 h of incubation; the highest doses of SB(i.e., 1.8 m L g–1 DM), in the absence of any EZ, quadratically increased(P<0.05) the initial delay before GP begins(L) and GP at different incubation times, with lowering b(quadratic effect, P<0.0001) and c(quadratic effect, P<0.0001; linear effect, P=0.0018). The GP was the lowest(P<0.05) when the highest SB level was combined with cellulose. There were SB?EZ interactions(P<0.001) for OMD, ME, the partitioning factor at 72 h of incubation(PF72), GY24, SCFA, MCP(P=0.0143), and p H(P=0.0008). The OMD, ME, GY24 and SCFA with supp lementation of SB extract at 1.8 m L g–1 DM were higher(P<0.001) than the other treatments, however,PF72 was lower(quadratic effect, P=0.0194) than the other levels. Both C and X had no effect(P>0.05) on OMD, p H, ME, GY24, SCFA and MP. The combination of SB with EZ increased(P<0.001) OMD, ME, SCFA, PF72 and GP24, whereas there was no impact on p H. It could be concluded that addition of SB extract, C, and X effectively improved the in vitro rumen fermentation, and the combination of enzyme with SB extract at the level of 1.2 m L g–1 was more effective than the other treatments. | Abdelfattah Z M Salem German Buendía-Rodríguez Mona M M Elghandour María A Mariezcurrena Berasain Francisco J Pea Jiménez Alberto B Pliego Juan C V Chagoyán María A Cerrillo Miguel A Rodríguez | 2015 | Journal of Integrative Agriculture2015，14，1： | 4 |
| 2 | Celiac disease serology in patients with different pretest probabilities: Is biopsy avoidable?显示文摘AIM: To establish the diagnostic performance of sev-eral serological tests, individually and in combination, for diagnosing celiac disease (CD) in patients with different pretest probabilities, and to explore potential se- rological algorithms to reduce the necessity for biopsy. METHODS: We prospectively performed duodenal biopsy and serology in 679 adults who had either high risk (n = 161) or low risk (n = 518) for CD. Blood samples were tested using six assays (enzyme-linked immunosorbent assay) that detected antibodies to tissue transglutaminase (tTG) and deamidated gliadin peptide (DGP). RESULTS: CD prevalence was 39.1% in the high-risk population and 3.3% in the low-risk group. In high-risk patients, all individual assays had a high diagnostic efficacy [area under receiving operator characteristic curves (AU ROC): 0.968 to 0.999]. In contrast, assays had a lower diagnostic efficacy (AU ROC: 0.835 to 0.972) in the low-risk group. Using assay combinations, it would be possible to reach or rule out diagnosis of CD without biopsy in 92% of cases in both pretest populations. We observed that the new DGP/tTG Screen assay resulted in a surplus compared to more conventional assays in any clinical situation. CONCLUSION: The DGP/tTG Screen assay could be considered as the best initial test for CD. Combinations of two tests, including a DGP/tTG Screen, might be able to diagnose CD accurately in different clinical scenarios making biopsy avoidable in a high proportion of subjects. | Emilia Sugai María L Moreno Hui J Hwang Ana Cabanne Adriana Crivelli Fabio Nach-man Horacio Vázquez Sonia Niveloni Julio Argonz Roberto Mazure Graciela La Motta María E Caniggia Edgardo Smecuol Néstor Chopita Juan C Gómez Eduardo Maurińo Julio C Bai | 2010 | World Journal of Gastroenterology2010，16，25： | 4 |
| 3 | Diabetes mellitus, revascularization and outcomes in elderly patients with myocardial infarction-related cardiogenic shock显示文摘Background The prognostic role of diabetes mellitus(DM)in elderly patients with myocardial infarction-related cardiogenic shock(MI-CS)remains controversial.Little information exists about the impact of intensive cardiac care unit(ICCU)and revascularization on outcomes of elderly patients with MI-CS.We aimed to assess the prognostic impact of DM according to age in patients with MI-CS,and to analyze the impact ICCU management and revascularization on in-hospital mortality in MI-CS patients at older ages.Methods Discharge episodes with diagnosis of CS associated with MI were selected from the Spanish National Health System’s Basic Data Set.Centers were classified according to their availability of ICCU.Main outcome measured was in-hospital mortality.Results A total of 23,590 episodes of MI-CS were identified,of whom 12,447(52.8%)were in patients aged≥75 years.The impact of DM on in-hospital mortality was different among age subgroups.While in younger patients,DM was associated to a higher mortality risk(0.52 vs.0.47,OR=1.12,95%CI:1.06–1.18,χ^2<0.001),this association became non-significant in older patients(0.76 vs.0.81,χ^2=0.09).Adjusted mortality rate of MI-CS aged≥75 years was lower in patients admitted to hospitals with ICCU(adjusted mortality rate:74.2%vs.77.7%,P<0.001)and in patients undergoing revascularization(74.9%vs.77.3%,P<0.001).Conclusions Prognostic impact of DM in patients with MI-CS was different according to age,with a significantly lower impact at older ages.The availability of ICCU and revascularization were associated with better outcomes in these complex patients. | Miquel Gual Albert Ariza-Solé María García Márquez Cristina Fernández JoséL Bernal Francesc Formiga María-Isabel Barrionuevo JoséC Sánchez-Salado Victòria Lorente Júlia Pascual Isaac Llaó Oriol Alegre Angel Cequier Javier Elola | 2020 | Journal of Geriatric Cardiology2020，17，10： | 2 |
| 4 | Copy number variations in chronic pancreatitis显示文摘 | Chen J M Masson E Le Maréchal C Férec C | 2009 | Cytogenetic and Genome Research (-)2009，，1： | 1 |
| 5 | Lithologic Mapping in the Mountain Pass,California Area Using Advanced Spaceborne Thermal Emission andReflection Radiometer(ASTER)Data显示文摘 | Rowan L C Mars J C | 2003 | Remote Sensing ofEnvironment2003，84，3： | 1 |
| 6 | Seeing I to I : A Pathway to Interpersonal Connectedness 显示文摘 | Pinel Elizabeth C Long Anson E Landau Mar J Alexander Kira Pyszczynski Tom | 2004 | Journal of Personality and Social Psychology2004，90，2： | 1 |
| 7 | Mapping mine wastes and analyzingareas affected by selenium-rich water runoff in southeastIdaho using AVIRIS imagery and digital elevation data 显示文摘 | Mars J C Crowley J K | 2003 | Remote Sensing of Environment2003，84，： | 1 |
| 8 | A sensitive new substrate for chymotrypsin 显示文摘 | Del Mar E G Largman C Brodrick J W | 1979 | Analytical Biochemistry1979，99，2： | 1 |
| 9 | 2001 SCCM/ESICM/ACCP/ATS/SIS international sepsis definitions conference 显示文摘 | Levy M M Fink M P Mar shall J C | 2003 | Crit Care Med2003，31，4： | 1 |
| 10 | Targeted mutation of plasma phospholipid transfer protein gene markedly reduces high-density lipoprotein levels显示文摘 | Bruce C Mar J | 1999 | J Clin Invest1999，103，： | 1 |
| 11 | Prevalence of autism in a United States population : the Brick township, New Jersey, investigation显示文摘 | Bertrand J Mars A Boyle C | 2001 | Pediatrics2001，108，5： | 1 |
| 12 | Mapping hydrothermally altered rocks at euprite, Nevada, using the advanced spaceborne thermal emission and reflection radiometer(ASTER), a new satellite-imagine system显示文摘 | Lawrence C Rowan Simon J Hook Michael J Abrams John C Mars | | Economic Geology0，98，： | 1 |
| 13 | Lois De Pertes De Charge Dans Les Conduits Karstiques: Base Th6orique Et Observations显示文摘 | Jeannin P Y Mar&hal J C | 1995 | Bulletin D'' Hydrog6- ologie De 1'' Universit6 De Neuchfitel1995，14，： | 1 |
| 14 | Clinical and social outcomes of adolescent self harm: population based birth cohort study 显示文摘 | Mars B Heron J Crane C | 2014 | BMJ2014，349，： | 1 |
| 15 | Seeing I to I : A Pathway to Interpersonal Connectedness 显示文摘 | Pinel Elizabeth C Long Anson E Landau Mar J Alexander Kira Pyszezynski Tom | 2004 | Journal of Personality and Social Psychology2004，90，2： | 1 |
| 16 | Hydrothermal Alteration on the Cascade Stratovolcanoes : a Remote Sensing Survey 显示文摘 | Crowley J K Hubbard B E Mars J C | 2003 | Geological Society of America Abstracts with Programs2003，35，6： | 1 |
| 17 | Lithologie Mapping of the Mordor, NT, Australia U]显示文摘 | Rowan L C Mars J C Simpson C J | 2005 | Remote Sensing of Environment2005，99，1： | 1 |
| 18 | Riparian pasture retirement effects on sediment, phosphorus and nitrogen in channelised surface run off from pastures显示文摘 | Smith C M Mar N Z J | 1989 | Freshwater Resource1989，23，： | 1 |
| 19 | Determination of phenols in wines by liquid chromatography with photodiode array and fluorescence detection 显示文摘 | Vinas P Lo'pez-Erroz C Mar'm-Hema'ndez J J | 2000 | Journal of Chromatography A2000，871，： | 1 |
| 20 | Lithologic Mapping in the Mountain Pass,California Area Using Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) Data显示文摘 | Rowan L C Mars J C | 2003 | Re-mote Sensing of Environment2003，84，35： | 1 |
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