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| 1 | No difference in mortality among ALPPS,two-staged hepatectomy,and portal vein embolization/ligation:A systematic review by updated traditional and network meta-analyses显示文摘Background:There is an ongoing debate on the feasibility,safety,and oncological efficacy of the associating liver partition and portal vein ligation for staged hepatectomy(ALPPS)technique.The aim of this study was to compare ALPPS,two-staged hepatectomy(TSH),and portal vein embolization(PVE)/ligation(PVL)using updated traditional meta-analysis and network meta-analysis(NMA).Data sources:Electronic databases were used in a systematic literature search.Updated traditional metaanalysis and NMA were performed and compared.Mortality and major morbidity were selected as primary outcomes.Results:Nineteen studies including 1200 patients were selected from the pool of 436 studies.Of these patients,315(31%)and 702(69%)underwent ALPPS and portal vein occlusion(PVO),respectively.Ninetyday mortality based on updated traditional meta-analysis,subgroup analysis of the randomized controlled trials(RCTs),and both Bayesian and frequentist NMA did not demonstrate significant differences between the ALPPS cohort and the PVE,PVL,and TSH cohorts.Moreover,analysis of RCTs did not demonstrate significant differences of major morbidity between the ALPPS and PVO cohorts.The ALPPS cohort demonstrated significantly more favorable outcomes in hypertrophy parameters,time to operation,definitive hepatectomy,and R0 margins rates compared with the PVO cohort.In contrast,1-year disease-free survival was significantly higher in the PVO cohort compared to the ALPPS cohort.Conclusions:This study is the first to use updated traditional meta-analysis and both Bayesian and frequentist NMA and demonstrated no significant differences in 90-day mortality between the ALPPS and other hepatic hypertrophy approaches.Furthermore,two high quality RCTs including 147 patients demonstrated no significant differences in major morbidity between the ALPPS and PVO cohorts. | Paschalis Gavriilidis Robert P Sutcliffe Keith J Roberts Madhava Pai Duncan Spalding Nagy Habib Long R Jiao Mikael H Sodergren | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，5： | 6 |
| 2 | The effect of early to mid-gestational nutrient restrietion on female offspring fertility and hypothalamic-pituitary-adrenal axis response to stress 显示文摘 | Long N M Nijland M J Nathanielsz P W | 2010 | J Anim Sci2010，88，6： | 1 |
| 3 | Facts & figures chemical R & D显示文摘 | Brennan M B Long J R Zurer P R | 1997 | C & EN1997，75，35： | 1 |
| 4 | Seismic response analysis of structures with velocity-dependent dampers 显示文摘 | OU J P LONG X LI Q S | 2007 | Journal of ConstructionalSteel Research2007，63，： | 1 |
| 5 | Kondo Resonance in a Single-molecule Transistor显示文摘 | LIANG W SHORES M P BOCKRATH M LONG J R PARK H | 2002 | Nature (London)2002，417，： | 1 |
| 6 | Group 4 metal olefin polymerization catalysts stabilized by bidentate O,Pligands显示文摘 | Long R J Gibson V C White A J P | | 0，，： | 1 |
| 7 | Role of NF-kappaB transcription factors in antiinflammatory and proinflammatory actions of mechanical signals显示文摘 | Agarwal S Deschner J Long P | 2004 | Arthritis Rheum2004，50，11： | 1 |
| 8 | One step synthesis of silica-coated nanoparticles at room temperature and their luminescence properties显示文摘 | Wang Y L Lu J P Huang X F Long J X Tong Z F | 2008 | Materials Letters2008，62，19： | 1 |
| 9 | Immunological differences in Eimeria maxima:effect of a mixed immmunizing inocculum on heterologous challenge显示文摘 | LONG P L MILLARD B J | 1979 | Parasitol1979，79，： | 1 |
| 10 | New evidence of mito- chondria dysfunction in the female Alzheimer' s dis-ease brain : deficiency of estrogen receptor - beta 显示文摘 | Long J He P Shen Y | 2012 | J Alzheimer'' s Dis2012，30，3： | 1 |
| 11 | The relationship of the degree of interconnection to permeability in fractured networks显示文摘 | Long J C S Witherspoon P A | 1985 | Journal of Geophysical Research1985，90，4： | 1 |
| 12 | Porous media equivalents for networks of discontinuous fractures显示文摘 | Long J C S Remer J S Wilson C R Witherspoon P A | 1982 | Water Resources Research1982，18，3： | 1 |
| 13 | Passive techniques for ground temperature control显示文摘 | Heuer C E Long E L Zarling J P | 1985 | Thermal Considerations in Frozen Ground Engineering Monograph Series by ASCE Technical Council on Cold Regions Engineering New York1985，1985，： | 1 |
| 14 | Lagands-unsupported metal-metal(M = Cu, Ag) interactions between closed-shell d^10 trinuclear systems显示文摘 | Singh K Long J R Stavropoulos P | 1997 | JAm Chem Soc1997，119，： | 1 |
| 15 | Association between con- tinuous positive airway pressure and changes in serum leptin in patients with obstructive sleep apnoea: a meta- analysis 显示文摘 | Zhang P Liu J Long S | 2014 | Sleep Breath2014，，： | 1 |
| 16 | Structural stud- ies of secondary crystallization products of the Fe23 B6 - type in a nano- crystalline FeCoB - based alloy 显示文摘 | Long J G Ohodnicki P R Laughlin D E | 2007 | Journal of Applied Physics2007，101，9： | 1 |
| 17 | New evidence of mitoehondria dysfunction in the female Alzheimer's disease brain: deficien- cy of estrogen receptor-beta显示文摘 | Long J He P Shen Y | 2012 | J Alzheimers Dis2012，30，3： | 1 |
| 18 | Mandibular coronoid fractures : treatment options 显示文摘 | Shen L Li J Li P Long J Tian W Tang W | 2013 | Oral Maxilfofac Surg2013，42，6： | 1 |
| 19 | Gas exchange measurements,what can they tell US about the underlying limitations to photosynthesis? Procedures and sources of error显示文摘 | Bernacchi C J | 2003 | Journal of Experimental Botany2003，54，392： | 1 |
| 20 | Eimeria: Further studies on the immunisation of young chickens kept in litter pens显示文摘 | Long P L Millard B J | 1979 | Avian Pathol1979，8，3： | 1 |
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