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| 1 | Safety of epinephrine for anaphylaxis in the emergency setting显示文摘BACKGROUND:While epinephrine is the recommended first-line therapy for the reversal of anaphylaxis symptoms,inappropriate use persists because of misunderstandings about proper dosing and administration or misconceptions about its safety.The objective of this review was to evaluate the safety of epinephrine for patients with anaphylaxis,including other emergent conditions,treated in emergency care settings.METHODS:A MEDLINE search using PubMed was conducted to identify articles that discuss the dosing,administration,and safety of epinephrine in the emergency setting for anaphylaxis and other conditions.RESULTS:Epinephrine is safe for anaphylaxis when given at the correct dose by intramuscular injection.The majority of dosing errors and cardiovascular adverse reactions occur when epinephrine is given intravenously or incorrectly dosed.CONCLUSION:Epinephrine by intramuscular injection is a safe therapy for anaphylaxis but training may still be necessary in emergency care settings to minimize drug dosing and administration errors and to allay concerns about its safety. | Joseph P Wood Stephen J Traub Christopher Lipinski | 2013 | World Journal of Emergency Medicine2013，4，4： | 7 |
| 2 | 胆碱酯酶和抗胆碱能药物在儿科术后谵妄中的应用显示文摘目的阐述抗胆碱能药物暴露、胆碱酯酶活性、炎症与儿童术后谵妄(pediatric delirium,PD)发生的关系。设计单中心前瞻性队列研究。场所德国一家三级医疗学术中心设有22张床位的PICU。对象连续入组大型择期手术后转入PICU的患儿。干预措施连续5 d对患儿进行谵妄检查。术后5 d内,每天两次筛查患儿谵妄状态。在术前和为期5 d的研究期间,每天测定1次乙酰胆碱酯酶和丁酰胆碱酯酶的血浆活性水平。计算每例患儿的抗胆碱能药物数量和抗胆碱能药物量表(anticholinergic drug scale,ADS)评分。测量方法与主要结果共纳入93例0~17岁患儿。抗胆碱能药物的数量和ADS评分与PD发生显著相关,而与疾病严重程度无关。基线胆碱酯酶水平在是否发生PD患儿间无差异。术后,丁酰胆碱酯酶(而不是乙酰胆碱酯酶)水平降低了33%,且与PD发生无关。术后丁酰胆碱酯酶水平与抗胆碱能药物数量、ADS评分和C-反应蛋白水平呈负相关。 | Meyburg J Ritsert ML Traube C 方伯梁(译) 钱素云(校) | 2021 | 中国小儿急救医学2021，28，2： | 2 |
| 3 | Accessory protein recruitment motifs in clathrin-mediated endocytosis 显示文摘 | BRETT T J TRAUB L M FREMONT D H | 2002 | Structure2002，10，： | 1 |
| 4 | Lymphocyte interleukin 2 production and responsiveness are altered in patients with primary myelodysplastic syndrome显示文摘 | Ayanlar-Batuman O Shevitz J Traub UC | 1987 | Blood1987，70，2： | 1 |
| 5 | A new PCR-based approach indicates the range of Clonorchis sinensis now extends to central Thailand 显示文摘 | Traub R J Macaranas J Mungthin M | 2009 | PLoS Negl Trop Dis2009，3，1： | 1 |
| 6 | Do Negative Results from Formal Systems Limit Scientific Knowledge? 显示文摘 | TRAUB J F | 1997 | Complexity1997，3，1： | 1 |
| 7 | Living donor kidney transplantation from the elderly donor 显示文摘 | WOLTERS H H SCHMIDT TRAUB H HOLZEN H J | 2006 | Transplant Proc2006，38，3： | 1 |
| 8 | Optimal order of one-point and muhipoint iteration 显示文摘 | KUNG H T TRAUB J F | 1974 | Journal of Association for Computing Machinery1974，21，4： | 1 |
| 9 | Legumain expres- sion as a prognostic factor in breast cancer patients显示文摘 | GAWENDA J TRAUB F LUCK H J | 2007 | Breast Cancer Research Treat2007，102，1： | 1 |
| 10 | Legumain expression as a prog-nostic factor in breast cancer patients显示文摘 | Gawenda J Traub F Luck H J | 2007 | Breast Cancer Res Treat2007，102，1： | 1 |
| 11 | The pep/ide content of colonic afferents decreases following colonic inflammation显示文摘 | Traub R J Hutchcroft K Gebhart GF | 1999 | Peptides1999，20，2： | 1 |
| 12 | Glial fibrillary acidic protein-positive cells of the kidney are capable of raising a protective bio- chemical barrier similar to astrocytes: expression of metallothionein in podocytes显示文摘 | Buniatian G H Hartmann H J Traub P | 2002 | Anat Ree2002，267，4： | 1 |
| 13 | Epidemiological and molecu]ar evidence supports the zoonotic transmis- sion of Giardia among humans and dogs living in the same community显示文摘 | TRAUB R J MONIS P T ROBERTSON I | 2004 | Parasitology2004，128，3： | 1 |
| 14 | Automotive electronics power up显示文摘 | J G Kassakian J M Miller N Traub | 2005 | IEEE Spectrum2005，37，5： | 1 |
| 15 | Humans, dogs and parasitic Zoonoses--unravelling the relation- ships in a remote endemic community in northeast In- dia using molecular tools显示文摘 | Traub R J Robertson I D Irwin P | 2003 | Parasitol Res2003，90，3： | 1 |
| 16 | A new PCR- based approach indicates the range of Clonorchis sinensis now extends to central Thailand 显示文摘 | Traub R J Macaranas J Mungthin M | 2009 | PLoS Negl Trop Dis2009，3，1： | 1 |
| 17 | The algebraic theory of matrix polynomials显示文摘 | Dennis J E Traub J F Weber R P | 1976 | SIAM J Numer Anal1976，13，： | 1 |
| 18 | Legumain expres-sion as a prognostic factor in breast cancer patients显示文摘 | Gawenda J Traub F Luck HJ | 2007 | Breast Cancer Res Treat2007，102，： | 1 |
| 19 | Molecular character- ization of Blastocystis isolates from zoo animals and their animal-keepers 显示文摘 | Parkar U Traub R J Vitali S | 2010 | Vet Parasito12010，169，： | 1 |
| 20 | i PS cell derived neuronal cells for drug discovery显示文摘 | Heilker R Traub S Reinhardt P Sch?ler HR Sterneckert J | 2014 | Trends Pharmacol Sci2014，35，10： | 1 |
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