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| 1 | Evaluation of C-reactive protein, an inflammatory marker, and infectious serology as risk factors for coronary artery disease and myocardial infarction显示文摘 | Jeffrey L Anderson John F Carlquist Joseph B Muhlestein Benjamin D Horne Sidney P Elmer | 1998 | Journal of the American College of Cardiology1998，，1： | 2 |
| 2 | Appropriateness of systemic treatments in unresectable metastatic well-differentiated pancreatic neuroendocrine tumors显示文摘AIM:To evaluate systemic treatment choices in unresectable metastatic well-differentiated pancreatic neuroendocrine tumors(PNETs)and provide consensus treatment recommendations.METHODS:Systemic treatment options for pancreatic neuroendocrine tumors have expanded in recent years to include somatostatin analogs,angiogenesis inhibitors,inhibitors of mammalian target of rapamycinand cytotoxic agents.At this time,there is little data to guide treatment selection and sequence.We therefore assembled a panel of expert physicians to evaluate systemic treatment choices and provide consensus treatment recommendations.Treatment appropriateness ratings were collected using the RAND/UCLA modified Delphi process.After studying the literature,a multidisciplinary panel of 10 physicians assessed the appropriateness of various medical treatment scenarios on a 1-9 scale.Ratings were done both before and after an extended discussion of the evidence.Quantitative measurements of agreement were made and consensus statements developed from the second round ratings.RESULTS:Specialties represented were medical and surgical oncology,interventional radiology,and gastroenterology.Panelists had practiced for a mean of15.5 years(range:6-33).Among 202 rated scenarios,disagreement decreased from 13.2%(26 scenarios)before the face-to-face discussion of evidence to 1%(2)after.In the final ratings,46.5%(94 scenarios)were rated inappropriate,21.8%(44)were uncertain,and30.7%(62)were appropriate.Consensus statements from the scenarios included:(1)it is appropriate to use somatostatin analogs as first line therapy in patients with hormonally functional tumors and may be appropriate in patients who are asymptomatic;(2)it is appropriate to use everolimus,sunitinib,or cytotoxic chemotherapy therapy as first line therapy in patients with symptomatic or progressive tumors;and(3)beyond first line,these same agents can be used.In patients with uncontrolled secretory symptoms,octreotide LAR doses can be titrated up to 60 mg every4 wk or up to 40 mg every 3 or 4 wk.CONCLUSION:Using the Delphi process allowed physician experts to systematically obtain a consensus on the appropriateness of a variety of medical therapies in patients with PNETs. | Jonathan R Strosberg George A Fisher Al B Benson Lowell B Anthony Bulent Arslan John F Gibbs Edward Greeno Renuka V Iyer Michelle K Kim William J Maples Philip A Philip Edward M Wolin Dasha Cherepanov Michael S Broder | 2015 | World Journal of Gastroenterology2015，21，8： | 2 |
| 3 | Reliability of an ear-bow transferinstrument 显示文摘 | Dae Gyun Choi John F Bowley David B Marx | 1999 | J Prosthet Dent1999，82，： | 1 |
| 4 | Shock tube pyrolysis of pyridine显示文摘 | John C Mackie Meredith B ColketⅢ Peter F Nelson | 1990 | J Phys Chem1990，94，10： | 1 |
| 5 | R N A expression of breast cancer resistance protein, lung resistance-related protein, muhidrug resistance-associated protein 1 and 2, and muhidrug resistance gene 1 in breast cancer: correlation with chemo-therapeutic re sponse 显示文摘 | Herman B John A F Max ime P L | 2003 | Clin Cancer Res2003，2，9： | 1 |
| 6 | Estimation of tropical forest structural characteristics using large-footprint lidar显示文摘 | Jason B Drake Ralph O Dubayah David B Clark Robert G Knox J.Bryan Blair Michelle A Hofton Robin L Chazdon John F Weishampel Steve Prince | 2001 | Remote Sensing of Environment2001，，2： | 1 |
| 7 | Coronary hemodynamic and metabolic studies of the coronary slow flow phenomenon显示文摘 | John F Beltrame Sananand B Limaye Ronald D Wuttke John D Horowitz | 2003 | American Heart Journal2003，，： | 1 |
| 8 | The use of internal stents in chronicureteral obstruction 显示文摘 | Julia F Yige B John GC | 2015 | The Journal of Urology2015，193，5： | 1 |
| 9 | Transient expression and insertional mutagenesis of Puccinia triticina using biolistics显示文摘 | CRAIG A W LES J S GUUS B CLARKE G RICHARD C S MERLE E JOHN P F | 2005 | Functional & Integrative Genomics2005，12，： | 1 |
| 10 | Shock tube pyrolysis of pyrrole and kinetics modelling显示文摘 | John C Mackie Meredith B ColketⅢ Peter F Nelson | 1991 | Int J Chem Kinet1991，23，8： | 1 |
| 11 | Characterization of adsorbed species on TiO2 after photocatalytic oxidation of toluene显示文摘 | Catherine M B John L F 2001 | 2001 | J Catal2001，200，1： | 1 |
| 12 | Some properties of paucidisperse gymnosperm lignin sulfonates of different molecular weights显示文摘 | RICHARD F B JOHN A N JOSEPH L M | | 0，，04： | 1 |
| 13 | 查看详情显示文摘 | Elaine M T Donald J L J John H.L Debbie A M Peter B F Karen B | | 0，，： | 1 |
| 14 | Measuring micro-fibrillar angles using light microscopy 显示文摘 | JOHN F S BENDTSEN B A | 1980 | Wood Sci1980，17，4： | 1 |
| 15 | Image Texture Analysis:Methods and Comparisons显示文摘 | Manish H B Liu J J John F M | 2004 | Chemometrics and Intelligent Laboratory Systems2004，72，： | 1 |
| 16 | CD4 ^+ T lymphocytes me- diate in vivo clearance of plasmid DNA vaccine antigen expres sion and potentiate CD8^+ T cell immune responses显示文摘 | Ralf G L John R G Kwesi F B | 2008 | Blood2008，112，12： | 1 |
| 17 | Composition and varlability of leachate from recent and aged areas within a municipal landfill显示文摘 | John K Jerry E O F B D | 1995 | Water Environ Res1995，61，2： | 1 |
| 18 | Administration of raw onion inhibits platelet-mediated thrombosis in dogs 显示文摘 | William H B John D F Hashim E O | 2001 | Nutrition2001，131，10： | 1 |
| 19 | Preoperative transcatheter closptal defects of congenital muscular ventricular septal defects 显示文摘 | BRIDGES NANCY D PERRY STANTON B KEANE JOHN F | 1991 | N Eng Med1991，324，： | 1 |
| 20 | Miscanthus biomass production for energy in Europe and its potential contribution to decreasing fossil fuel carbon emissions显示文摘 | John C Paul F Michael B | 2004 | Global Change Biology2004，10，： | 1 |
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