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| 1 | Driving gene-engineered T cell immunotherapy of cancer显示文摘妄想的抗原受体(汽车) 设计基因的 T 房间治疗保持潜力与终末期癌在病人的生活有有意义的差别。为十年,癌症治疗基于生物物理的参数,与到 debulk 的外科的切除术,由放射和化疗列在后面指向很快成长的肿瘤房间,当时主要 sparing 静止正常纸巾。一突破与 allogeneic 骨头髓发生了与白血病为病人移植,它提供了一有时药品治疗。为稳固的肿瘤的采纳房间治疗的地与发现被建立渗入肿瘤的淋巴细胞能与变形黑瘤被扩展并且使用到对待和甚至痊愈病人。肿瘤特定的 T 房间受体(TCR ) 被识别并且设计了进耐心的外部血淋巴细胞,它也被发现治疗肿瘤。然而,这些被耐心的 HLA 限制限制。紧随来汽车的产生,把抗体的优美识别与一个 T 房间的受动器功能相结合。为与先进 B 房间恶意的多重表格对待病人的指向 CD19 的汽车的来临取得了大成功,与多达 95% 反应率。然而,到稳固的肿瘤的适用的汽车治疗刚开始了,但是已经,某些因素被弄明白:肿瘤目标具有最大的重要性让临床医生不做伤害;并且稳固的肿瘤与 hematologic 相比对汽车治疗不同地作出回应。这里,我们考察临床的设计基因的 T 房间免疫疗法,它的成功,挑战,和未来的状态。 | Laura A Johnson Carl H June | 2017 | Cell Research2017，27，1： | 37 |
| 2 | History of the infantile hepatic hemangioma:From imaging to generating a differential diagnosis显示文摘We aim to provide an up-to-date summary of infantile hepatic hemangioma(IHH) and its misnomers and to dialectically present the differential diagnosis of these rare entities of the liver.Eligible peer-reviewed articles on hepatic infantile hemangiomas,published between 2000 and 2015,were reviewed for this study.IHH is the most common hepatic vascular tumor in children.Once a liver mass is identified in an infant,the differential diagnosis ranges from vascular malformations to benign and malignant tumors including mesenchymal hamartoma,hepatoblastoma,metastatic neuroblastoma,so careful physical examination,imaging studies,and,if indicated,tumor markers and biopsy,are of pivotal importance to ascertain the correct diagnosis.Despite the benign nature of IHHs,some of these lesions may demand medical and/or surgical intervention,especially for multiple and diffuse IHH.Complications can include hepatomegaly,hypothyroidism and cardiac failure.Therefore,a close follow-up is required until complete involution of the lesions.We propose an algorithm to guide the physicians towards the proper management of hepatic lesions. | Maria Gnarra Gerald Behr Alison Kitajewski June K Wu Sudha A Anupindi Carrie J Shawber Nick Zavras Dimitrios Schizas Chris Salakos Konstantinos P Economopoulos | 2016 | World Journal of Clinical Pediatrics2016，5，3： | 27 |
| 3 | A supply chain network equilibrium model with random demands 显示文摘 | DONG June ZHANG Ding NAGURNEY A | 2004 | Europe- an Journal of Operational Research2004，156，1： | 1 |
| 4 | Thompson CB: The B7 and CD28 receptor families显示文摘 | June C H Bluestone J A Nadler L M | 1994 | Immunol Today1994，15，7： | 1 |
| 5 | Isolation of the tomato Cf-9 gene for resistance to Cladosporium fulvum by transpon tagging显示文摘 | Junes D A | 1994 | Science1994，266，： | 1 |
| 6 | Adaptive Hopfield Neural Networks for Economic Load Dispatch 显示文摘 | Lee K Y Sode-Yome A June H P | 1998 | Power Systems IEEE Transactions on1998，13，2： | 1 |
| 7 | High self control predicts good adjustment,less pathology,better grades,and interpersonal success显示文摘 | June T P Roy B F Luzio B A | | 0，，02： | 1 |
| 8 | Osteop rotegerin inhibits ar- tery calcigtication induced by warfarin and by vitamin D 显示文摘 | Price P A June H H Buekley J R | 2001 | Arte- rioseler Thromb Vasc Biol2001，21，10： | 1 |
| 9 | Osteoprotegerin inhibits artery calcification induced by warfarin and by vitamin D 显示文摘 | Price P A June H H Buckley J R | 2001 | Arterioscler 3hromb Vasc Biol2001，21，10： | 1 |
| 10 | Considerations for the clinical applicationof chimeric antigen receptor T cells: observations froma recombinant DNA Advisory Committee Symposiumheld June 15,2010 显示文摘 | Ertl H C Zaia J? Rosenberg S A June C H Dotti G Kahn J | 2011 | Cancer Res2011，71，： | 1 |
| 11 | Use of collaborative testing to promote nursing student success 显示文摘 | Eastridge June A | 2014 | Nurse Educ2014，39，1： | 1 |
| 12 | CT healthcare failure mode effect analy- sis(HFMEA) :The misadministration of IV contrast in outpatients 显示文摘 | Kathy OP Ben A June C | 2007 | Radiology Management2007，29，1： | 1 |
| 13 | Radiation and immunotherapy: a synergistic combination显示文摘 | Kalbasi A June CH Haas N | 2013 | J Clin Invest2013，123，7： | 1 |
| 14 | Expression of Distinct Self-Incompatibility Specificities in Arabidopsis thaliana显示文摘 | Boggs Nathan A Dwyer Kathleen G Shah Paurush McCulloch Amanda A Bechsgaard Jesper Schierup Mikkel H Nasrallah Mikhail E Nasrallah June B | 2009 | Genetics2009，，4： | 1 |
| 15 | Military and civilianmedia coverage of suicide显示文摘 | Edwards-Stewart A Kinn JT June JD | 2011 | Arch Suicide Res2011，15，4： | 1 |
| 16 | The predictive utility of com- puter- simulated exercinieal technique 显示文摘 | Sarah A G Lisa P D June A S | 2003 | J Dent Educ2003，67，11： | 1 |
| 17 | Effect of initial s-phase content of SiC on microstructure and mechanical properties of SiC-TiC composites显示文摘 | Hyun G A Young W K June G L | 2001 | J Eur Ceram Soc2001，21，1： | 1 |
| 18 | Molecular dynamics study of methane and xenon in silicalite显示文摘 | June R L Bell A T Theodorou D N | 1990 | J Phys Chem1990，94，21： | 1 |
| 19 | A supply chain network equilibrium model 显示文摘 | Nagurney A Dong June Zhang Ding | 2002 | Transportation Research Part E2002，38，： | 1 |
| 20 | Sensitivity and speicificity of PCR for detection of Mycobacterium tuberculosis: a blind comparison study among seven laboratories 显示文摘 | NOORDHOEK G T KOLK A H B JUNE G | 1994 | Journal of Clinical Microbiology1994，32，2： | 1 |
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