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| 1 | Pain sensation in pancreatic diseases is not uniform: The different facets of pancreatic pain显示文摘AIM: To systematically characterize specific pain patterns in the most frequent pancreatic diseases.METHODS: Pain in patients with chronic pancreatitis(n = 314), pancreatic cancer(n = 469), and other pancreatic tumors(n = 249) including mucinous(n = 20) and serous cystadenoma(n = 31), invasive(n = 37) and non-invasive intraductal papillary mucinous neoplasia(IPMN; n = 48), low stage(n = 18) and high stage neuroendocrine neoplasia(n = 44), and ampullary cancer(n = 51) was registered and correlated with clinicopathological data. Survival times were estimated by the Kaplan-Meier method. Patients alive at the follow-up time were censored. Survival curves were compared statistically using the log-rank test.RESULTS: Forty-nine point one percent of pancreatic cancer patients revealed no pain, whereas in chronic pancreatitis only 18.3% were pain free. In contrary, moderate/severe pain was registered in 15.1% in pancreatic cancer patients that was increased in chronic pancreatitis with up to 34.2%. Serous cystadenoma was asymptomatic in most cases(58.1%), whereas 78.9% of all mucinous cystadenoma patients suffered pain. In neuroendocrine neoplasia pain was not a key clinical symptom since 64% of low stage neuroendocrine neoplasia and 59% of high stage neuroendocrine neoplasia patients were pain free. Cancer localization in the pancreatic body and patients with malignant pancreatic neoplasms were associated with more severe pain. Tumor grading and stage did not show any impact on pain. Only in pancreatic cancer, pain was directly associated with impaired survival.CONCLUSION: Pancreatic pain depicts different patterns of abdominal pain sensation according to the respective pancreatic disorder and does not allow a unification of the term pancreatic pain. | Jan G D'Haese Mark Hartel Ihsan Ekin Demir Ulf Hinz Frank Bergmann Markus W Büchler Helmut Friess Güralp O Ceyhan | 2014 | World Journal of Gastroenterology2014，20，27： | 8 |
| 2 | Fabrication of Fe-Si-B based amorphous powder cores by cold pressing and their magnetic properties显示文摘 | Kim Y B Jans D H Seok H K | | 0，，： | 1 |
| 3 | Marketing percolation显示文摘 | J Goldenberg B Libai S Solomon N Jan D Stauffer | 2000 | Physica A: Statistical Mechanics and its Applications2000，，1： | 1 |
| 4 | PRISMA-DB A parallel main memory relational DBMS 显示文摘 | PETER M G A CAREL A V D B JAN F | 1992 | IEEE Transactions on Knowledge and Data Engineering1992，4，6： | 1 |
| 5 | The identification by ^1H and ^13C-nmr spectroscopy of sucrose, 1-kestose, and neokestose in mixtures present in plant extracts显示文摘 | Andre D B Jan V L | 1991 | Carbohydrate Research1991，211，： | 1 |
| 6 | Treatment of respiratory syncytial virus bronchiolitis: 1995poll of members of the European Society for Pediatric Infection Disease显示文摘 | JAN L L KIMPEN M D URS B | 1997 | Pediatric Infection Disease J1997，16，5： | 1 |
| 7 | Modeling ofgeneric slung load system 显示文摘 | MORTEN B JAN D B ANDERS C | 2009 | Journal of Guidance Control and Dynamics2009，32，2： | 1 |
| 8 | A Study of Innovation Design on Taiwan Culture Creative Product: A Case Study of the Facial Mask of Ba Ja Jang显示文摘 | CHEN C H CHEN B C JAN C D | 2009 | Lecture Notes in Computer Science2009，，： | 1 |
| 9 | ML estimation of time and frequency offset in OFDM systems 显示文摘 | JAN - JAAP V D B MAGNUS S | 1997 | IEEE Transactions on Signal Processing1997，45，7： | 1 |
| 10 | Treatment of respiratory syneytial Virus brohchiolitics:1995 Pod of the European Society for pediatric infections diseases显示文摘 | Jan L L Kimpen M D Urs B | 1997 | Pediatric Infect Dis1997，16，5： | 1 |
| 11 | Effect of surfactant on the co - electrodeposition of the nano - sized ceria particle in the nickel matrix 显示文摘 | RAN JAN S SUMIT B SIDDHARTHA D | 2010 | Journal of Alloys and Compounds2010，489，2： | 1 |
| 12 | Development of human protein reference database as an initial platform for approaching systems biology in humans 显示文摘 | PERI S NAVARRO J D AMANCHY R KRISTIANSEN T Z JONNALAGADDA C K SURENDRANATH V NIRAN JAN V MUTHUSAMY B GANDHI T K GRONBORG M IBARROLA N DESHPANDE N SHANKER K SHIVASHANKAR H N RASHMI B P RAMYA M A ZHAO Z CHANDRIKA K N PADMA N HARSHA H C YATISH A J KAVITHA M P MENEZES M CHOUDHURY D R SURESH S GHOSH N SARAVANA R CHANDRAN S KRISHNA S JoY M ANAND S K MADAVAN V JOSEPH A WONG G W SCHIEMANN W P CONSTANTINESCU S N HUANG L KHOSRAVI-FAR R STEEN H TEWARI M GHAFFARI S BLOBE G C DANG C V GARCIA J G PEVSNER J JENSEN O N ROEPSTORFF P DESHPANDE K S CHINNAIYAN A M HAMOSH A CHAKRAVARTI A PANDEY A | 2003 | Genome Research2003，13，10： | 1 |
| 13 | Characterization of polyploid wheat genomic diversity using a high-density 90 000 single nucleotide polymorphism array 显示文摘 | Wang SC Debbie W Kerrie F Alexandra A Shiaoman C Bevan EH Marco M Silvio S Sara GM Luigi C Anna MM Alex W Stuart S Gary B Ralf W Joerg P International Wheat Genome Sequencing Consortium Morten L Diane M Rudi A Rudy D Gina BG Abraham K Alina RA Catherine F Jerome S Michele M Curtis P Luo MC Jan DMM Jorge D Martin G Roberto T Cindy L Ivan M Colin C Keith JE Matthew H Eduard A | 2014 | Plant Biotechnol J2014，12，： | 1 |
| 14 | Advanced sludge treatment affects extracellular polymeric substance to improve activated sludge dewatering显示文摘 | Elisabeth N Jan B Raf D H | 2004 | Hazardous Materials2004，106，： | 1 |
| 15 | Marketing percolation显示文摘 | Goldenberg J Libai B Solomon S Jan N Stauffer D | 2000 | Physica A2000，284，： | 1 |
| 16 | Film properties of hydroxypropyl starch 显示文摘 | Waltraud V Jan D Johannes B | 2004 | Starch2004，56，： | 1 |
| 17 | Passively mode-locked diode laser with optimized dispersion man- agement 显示文摘 | Jan C B Rouven O H P Benjamin D | 2015 | IEEE Journal of Selected Topics in Quan- tum Electronics2015，21，11： | 1 |
| 18 | Marketing percolation显示文摘 | J Goldenberg B Libai S Solomon N Jan D Stauffer | 2000 | Physica A: Statistical Mechanics and its Applications2000，，1： | 1 |
| 19 | Random Forests as a Tool for Ecohydrological Distribution Modelling显示文摘 | Jan P Bernard D B Niko E C V Roeland S Sven D Piet D B Willy H | 2007 | Ecological Modelling2007，207，24： | 1 |
| 20 | Random forests as a tool for ecohydrological distribution modelling显示文摘 | JAN P BERNARD D B NIKKO E C | 2007 | Ecol Model2007，207，24： | 1 |
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