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| 1 | Significant decrease in prevalence ofHelicobacter pylori in the Czech Republic显示文摘AIM:To study possible decrease in prevalence of Helicobacter pylori(H.pylori) infection in the Czech Republic within a 10-year period.METHODS:A total of 22 centres entered the study.The catchment areas of these centres covered cities and towns with more than 20 000 inhabitants,smaller towns(≤ 20 000 inhabitants) with surrounding villages and rural areas,and were spread over the whole country,corresponding well to the geographical distribution of the Czech population.A total of 1 837 subjects(aged 5-98 years) took part in the study,randomly selected out of 38 147 people from the general population.H.pylori infection was investigated by means of a 13 C-urea breath test.Breath samples in duplicates were analysed using isotope ratio mass spectrometry.The cut-off point was 3.5.Social and demographic characteristics were based on data from self-completed questionnaires.RESULTS:The overall prevalence of H.pylori infection was 23.5%(430/1826),and 4.8%(20/420) in children aged 15 or less.There was no statistically significant difference in prevalence between males(24.3%;208/857) and females(22.9%,222/969,P = 0.494).H.pylori infection was strongly associated with higher age,among subjects aged 55+ years,prevalence of H.pylori infection was 39.8%(252/633,P < 0.001).The highest prevalence of H.pylori infection was found among persons aged 55-64 years(43.9%,97/221) and 75+ years(37.9%,58/153).Among study subjects aged 15+ years,prevalence of H.pylori infection was significantly increased in those with lowest education(odds risk 3.19,95% CI 1.87-5.47).Compared to never married(14.1%),the prevalence of H.pylori infection was statistically significantly higher among married(35.4%,246/694,P < 0.001),divorced(36.8%,49/133,P < 0.001) and widowed study subjects(40.2%,45/112,P < 0.001),both in minimally and fully adjusted analysis.There was no significant difference in the prevalence of H.pylori infection between married and widowed subjects(35.4%,246/694 vs 40.2%,45/112,P = 0.389).There was little variation in smoking prevalence across categories of smoking and there was no evidence of an increased risk ofH.pylori infection among current or past smokers in our data(odds risk 1.04 with 95% CI 0.78-1.40 for current smokers;odds ratio 0.83 with 95% CI 0.60-1.16 for former smokers).The current prevalence of H.pylori in 2011 was significantly lower compared to the prevalence reported from identical geographical areas in 2001(23.5%vs 41.7%,P < 0.001).CONCLUSION:The overall prevalence of H.pylori infection in the general population has fallen substantially in the Czech Republic over the past 10 years. | Jan Bure Marcela Kopáová Ilona Koupil Bohumil Seifert Miluka kodová Fendrichová Jana pirková Viktor Voíek Stanislav Rejchrt TomáDouda Norbert Král Ilja Tachecí | 2012 | World Journal of Gastroenterology2012，18，32： | 8 |
| 2 | Central nervous system vasculitis and polyneuropathy as first manifestations of hepatitis C显示文摘Sensory or motor peripheral neuropathy may be observed in a significant proportion of hepatitis C virus (HCV)-infected patients.However,central nervous system (CNS) involvement is uncommon,especially in cryoglobulin-negative subjects.We describe a case of peripheral neuropathy combined with an ischemic CNS event as primary manifestations of chronic HCV infection without cryoglobulinemia.Significant improvement was observed after antiviral therapy.We discuss the spectrum of neurological manifestations of HCV infection and review the literature. | Roberto J Carvalho-Filho Janaína Luz Narciso-Schiavon Luciano HL Tolentino Leonardo L Schiavon Maria Lucia G Ferraz Antonio Eduardo B Silva | 2012 | World Journal of Gastroenterology2012，18，2： | 3 |
| 3 | Expression of miRNAs-106b in conventional renal cell carcinoma is a potential marker for predic- tion of early metastasis after nephrectomy显示文摘 | Ondrej S Jana J Radek L | 2010 | J Exp Clin Cancer Res2010，29，1： | 1 |
| 4 | Wet chemical synthesis of silver nanorods and nanowires of controllable aspect ratios显示文摘 | Jana N R Gearheart L Murphy C | 2001 | J Chem Commun2001，，： | 1 |
| 5 | Using Office hours wisely 显示文摘 | JANA L PRESSLER CAROLE A KENNER | 2009 | Nurse Educator2009，，5： | 1 |
| 6 | Drag on Hydroid-Fouled Nets – An Experimental Approach显示文摘The present study investigated the drag increase on aquaculture nets due to biofouling of the colonial hydroid Ectopleura larynx. It had two main parts: firstly the growth characteristics of E. larynx were investigated by use of field tests at a Norwegian aquaculture site; secondly the hydrodynamic drag on the fouled twines was studied in a towing tank by using fabricated models of net twines with artificial hydroid fouling. In the field tests, the growth of the hydroids was first measured after three weeks of immersion and then again after six weeks. During this interval, the density of hydroids and the thickness of the hydroid stem were almost constant(1.4 hydroids/mm and 0.29 mm, respectively), while the average length of the hydroids increased from 6.4 to 11.2 mm. The hydroid length followed a Rayleigh distribution, while the thickness was normal(Gaussian) distributed. Replicas of twines with three different levels of hydroid growth were made(1.5 hydroids/mm twine, hydroid length 9 mm, 16 mm and 20 mm), and the drag on these twines was measured at different towing velocities(0.1 to 1.4 m/s) and with different twine configurations. For the twine with the shortest hydroids(9 mm), the drag was from 1.5 times(Re=4000) to 2.2 times(Re=1000) the drag on a clean twine. For the longest hydroids(21 mm), the drag was 2 times and 3.8 times, respectively. | Pl LADER David W. FREDRIKSSON Jana GUENTHER Zsolt VOLENT Nina BLOCHER David KRISTIANSEN Lars GANSEL Jud DECEW | 2015 | China Ocean Engineering2015，29，3： | 1 |
| 7 | ABCG2 expression, function, and promoter methylation in human multiple myeloma显示文摘 | Joel GT Jana L | 2006 | Blood2006，108，12： | 1 |
| 8 | Evidence for Seed-Mediated Nucleation in the Chemical Reduction of Gold Salts to Gold Nanoparticles显示文摘 | Jana N R Gearheat L Murphy L | 2001 | J Chem Mater2001，13，： | 1 |
| 9 | The effect of shear and oil/water ratio on the required hydrophile-lipophile balance tbr emulsification 显示文摘 | KLOET JANA KLOET SCHRAMM LAURIER L | 2002 | Journal of Surfactants and detergents2002，5，1： | 1 |
| 10 | The nucleotide profile of human milk显示文摘 | Janas L M Picciano M F | 1982 | Pediatr Res1982，16，： | 1 |
| 11 | Seed - Mediated Growth Approach for Shape - Controlled Synthesis of Spheroidal and Rod - like Gold Nanoparticles Using a Suffactant Template 显示文摘 | N R Jana L Gearheart C J Murphy | 2001 | Adv Mater2001，13，： | 1 |
| 12 | Hygrothermal effects on properties of highly conductive epoxy/graphite composites for applications as bipolar plates显示文摘 | DU L JANA S C | 2008 | Journal of Power Sources2008，182，1： | 1 |
| 13 | Seed-Mediated Growth Approach for Shape-Controlled Synthesis of Spheroidal and Rod-Like Gold Nanoparticles Using a Surfaetant Template显示文摘 | Jana N R Gearheart L Murphy C J | 2001 | Advanced Materials2001，13，18： | 1 |
| 14 | Preparation of core-shell latex particles by emulsion co-polymerization of styrene and butyl acrylate, and evaluation of their pigment properties in emulsion paints显示文摘 | Borthakur L J Jana T Dolui S K | 2010 | Journal of Coatings Technology and Research2010，7，6： | 1 |
| 15 | Differential expression of his- tone deacetylases HDAC1,2 and 3 in human breast cancer--overex- pression of HDAC2 and HDAC3 is associated with clinicopathological indicators of disease progression 显示文摘 | Mtlller BM Jana L Kasajima A | 2013 | BMC Cancer2013，13，： | 1 |
| 16 | Developing a culture of emer- gency preparedness education in nursing 显示文摘 | Kenner Carole A Pressler Jana L | 2014 | Nurse Educ2014，39，1： | 1 |
| 17 | Seeding growth for size control of 524 nm diameter gold nanoparticles显示文摘 | Jana R N Gearheart L | 2001 | Langmuir2001，17，： | 1 |
| 18 | Wet Chemical Synthesis of High Aspect Ratio Cylindrical Gold Nanorods 显示文摘 | Jana N R Gearheart L Murphy C J | 2001 | J Phys Chem B2001，105，： | 1 |
| 19 | Effect of chem- ical doping of boron and nitrogen on the electronic, op- tical, and electrochemical properties of carbon nano- tubes 显示文摘 | JANA D SUN C L CHEN L C | 2013 | Progress in Materials Science2013，58，5： | 1 |
| 20 | Wet Chemical Synthesis of Silver Nanorods and Nanowires of Controllable Aspect Ratio 显示文摘 | Jana N R Gearheart L Murphy C J | 2001 | Chemical Communications2001，7，： | 1 |
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