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| 1 | 应用Models-3/CMAQ研究长三角区域大气污染及输送显示文摘选用美国国家环保局第3代空气质量模式(Models-3,/CMAQ),配合中尺度气象模式(MM5)进行研究,模拟了2001年1、7月份长江三角洲区域冬夏季典型天气条件下大气层二次污染物臭氧及颗粒物的浓度分布及输送状况。采用2001年冬.夏季各10d的小时监测数据对模式验证。结果表明,Models-3/CMAQ对O3、PM10的模拟相关系数分别为0.77和052;一致性指数分别达到081和0.99。模型对于O3略微低估,标准偏差为-31%,而对于PM10则有所高估,标准偏差为46%。对长三角7月份O3浓度及1月份PM10的模拟结果显示,7月份长三角区域16个主要城市O3日均浓度集中在0.043~0.086mg/m^3之间,其中,泰州、扬州.湖州、镇江O3月日均浓度相对较高,均超过0.064mg/m3o模拟时段内O3最高小时浓度达0.276mg/m^3。1月份整个模拟区域PM10月日均浓度为O056mg/m^3,其中,南京市PM10日均浓度最高,达0.080mg/m^3模拟时段内PM10最高小时浓度达0.432mg/m^3研究表明,长三角地区存在明显的污染物输送现象,大气污染已经从局地污染转化为区域污染。 | 李莉 陈长虹 黄海英 黄成 李作攀 Joshua S Fu Carey J Jang David G Streets | 2007 | 上海环境科学2007，26，4： | 11 |
| 2 | 陶瓷部件的浆料打印快速成型(英文)显示文摘采用Sanders公司的四打印头快速成型机进行了陶瓷部件的浆料打印成型实验 ,实际测试了所用四打印头快速成型机的打印工作条件 ,考察了石蜡和挥发性介质两种浆料技术路线 ,并采用石蜡为介质制备了钛酸钡陶瓷浆料 ,研究了其流变性能 .实验表明 ,虽然偶联剂的加入可以降低石蜡介质浆料的粘度 ,但是粘度足够低的可打印浆料的固相含量太低 [约 3 % (involume)以下 ] ,打印成型后不能完全烧结 ,因此 ,要通过打印成型出可完全烧结的陶瓷部件便只能采用挥发性液体作为浆料介质 。 | 王树海 Jang J H Schulze W A Pilgrim S M | 2001 | 硅酸盐学报2001，29，4： | 10 |
| 3 | Prediction of clinically actionable genetic alterations from colorectal cancer histopathology images using deep learning显示文摘BACKGROUND Identifying genetic mutations in cancer patients have been increasingly important because distinctive mutational patterns can be very informative to determine the optimal therapeutic strategy. Recent studies have shown that deep learning-based molecular cancer subtyping can be performed directly from the standard hematoxylin and eosin(H&E) sections in diverse tumors including colorectal cancers(CRCs). Since H&E-stained tissue slides are ubiquitously available, mutation prediction with the pathology images from cancers can be a time-and cost-effective complementary method for personalized treatment.AIM To predict the frequently occurring actionable mutations from the H&E-stained CRC whole-slide images(WSIs) with deep learning-based classifiers.METHODS A total of 629 CRC patients from The Cancer Genome Atlas(TCGA-COAD and TCGA-READ) and 142 CRC patients from Seoul St. Mary Hospital(SMH) were included. Based on the mutation frequency in TCGA and SMH datasets, we chose APC, KRAS, PIK3CA, SMAD4, and TP53 genes for the study. The classifiers were trained with 360 × 360 pixel patches of tissue images. The receiver operating characteristic(ROC) curves and area under the curves(AUCs) for all the classifiers were presented.RESULTS The AUCs for ROC curves ranged from 0.693 to 0.809 for the TCGA frozen WSIs and from 0.645 to 0.783 for the TCGA formalin-fixed paraffin-embedded WSIs.The prediction performance can be enhanced with the expansion of datasets. When the classifiers were trained with both TCGA and SMH data, the prediction performance was improved.CONCLUSION APC, KRAS, PIK3CA, SMAD4, and TP53 mutations can be predicted from H&E pathology images using deep learning-based classifiers, demonstrating the potential for deep learning-based mutation prediction in the CRC tissue slides. | Hyun-Jong Jang Ahwon Lee J Kang In Hye Song Sung Hak Lee | 2020 | World Journal of Gastroenterology2020，26，40： | 3 |
| 4 | Thermodynamic theory of the lead Zirconate-Titanate solid solution system, Part V: theoretical caculations显示文摘 | HAUN M J FURMAN E JANG S J | 1989 | Ferroelectrics1989，99，1： | 2 |
| 5 | 显示文摘 | Jang G H Hong S J Kim D K | 2000 | IEEE Transactions On Magnetics2000，36，5： | 2 |
| 6 | A study on comparison of optimization performances between immune algorithm and other heuristic algorithms 显示文摘 | Sung C J Jang Hyun Kyo Hahn Song Yop | 1998 | IEEE Trans on Magnetics1998，34，5： | 2 |
| 7 | Roles of Ba/Ti ratios in the dielectric properties of BaTiO3 ceramics显示文摘 | LEE J K HONG K S JANG J W | 2001 | J Am Ceram Soc2001，84，9： | 2 |
| 8 | A new calcineurin inhibition domain in Cabinl 显示文摘 | Jang H Cho E J Youn H D | 2007 | Biochem Biophys Res Commun2007，359，1： | 1 |
| 9 | Metallurgical analyses of fracture characteristics in weldHeat-affected Zones of cryogenic steel (Ⅰ)-Evaluation of local brittle zone phenomena using synthetic CGHAZ Specimens 显示文摘 | JANG J JU J-B | 2000 | Journal of Korean Institute of Metal and Materials2000，，7： | 1 |
| 10 | Expression of a bifunctional fusion of the Escherichia coli genes for trehalose 6-phosphate synthase and trehalose-6-phosphate phosphatase in transgenic rice plants increases trehalose accumulation and abiotic stress tolerance without stunting growth显示文摘 | Jang I C Oh S J Seo J S | 2003 | Plant Physiology2003，131，2： | 1 |
| 11 | Modeling and High -precision Control of a Ball-screw-drive Stage 显示文摘 | Chen C L Jang M J Lin K C | 2004 | Precision Engineering2004，28，： | 1 |
| 12 | Glucose and ethylene signal transduction crosstalk revealed by an Arabidopsis glucose-insensitive mutant 显示文摘 | ZHOU L JANG J C JONES T L | 1998 | PNAS1998，95，10： | 1 |
| 13 | Electrochemical study of hydrogen embrittlement and optimum cathodic protection potential of welded high strength steel显示文摘 | KIM S J JANG S K KIM J I | 2005 | Metals and Materials International2005，11，1： | 1 |
| 14 | Polymerase chain reaction(PCR)for human herpes virus 8 and heteroduplex PCR for clonality assessment in angiolymphoid hyperplasia with eosinophilia and Kimura's disease显示文摘 | Jang K A Ahn S J Choi J H | 2001 | J Cutan Pathol2001，28，： | 1 |
| 15 | 显示文摘 | Ryu S Park J H Jang H M | 2007 | Appl Phys Lett2007，91，14： | 1 |
| 16 | Antifungal activity of the methanol extract of Myristica malabarica fruit rinds and the active ingredients malabaricones against phytopathogenic fungi 显示文摘 | Choi H N Choi J G Jang S K | 2008 | Plant Pathol2008，24，3： | 1 |
| 17 | Co-metal clustering as the origin of ferromagnetism in Co-doped ZnO thin films显示文摘 | Park J H Kim M G Jang H M | 2004 | Appl Phys Lett2004，84，： | 1 |
| 18 | Effects of natural polysaccharides on the growth and peritoneal carcinomatosis of human gastric adenocarcinoma in a nude mouse model显示文摘 | BAE J S JANG K H JIN H K | 2006 | Cancer Letters2006，235，1： | 1 |
| 19 | Compression properties of dust cake of fine fly ashes from a fluidized bed coal combustor on a ceramic filter 显示文摘 | Choi J H Ha S J Jang H J | 2004 | Powder Technology2004，140，： | 1 |
| 20 | ANFIS:adaptive-network-based fuzzy inference system显示文摘 | JANG J | 1993 | IEEE Transactions on Systems Man Cybemetics1993，23，3： | 1 |
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