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| 1 | 酒精摄入、心脏生物标志物和心房颤动风险与不良结局显示文摘酒精摄入和新发心房颤动相关性证据不一,尤其是在低剂量下。该研究评估欧洲队列在整个饮酒范围内酒精摄入、生物标志物和新发心房颤动的关系。方法和结果:在一个以社区为基础的汇集队列中,研究者随访107845人,以评估酒精摄入(酒精种类和饮酒方式)与新发心房颤动的关系。研究者收集经典心血管病危险因素和新发心力衰竭的信息,并检测生物标记物氨基末端脑钠肽前体和高敏肌钙蛋白I。 | 陈嘉睿(译) 练桂丽((审校) Csengeri D Sprünker NA Di Castelnuovo A Niiranen T Vishram-Nielsen JK Costanzo S S derberg S Jensen SM Vartiainen E Donati MB Magnussen C Camen S Gianfagna F L chen ML Kee F Kontto J Mathiesen EB Koenig W Stefan B de Gaetano G J rgensen T Kuulasmaa K Zeller T Salomaa V Iacoviello L Schnabel RB | 2021 | 中华高血压杂志2021，29，2： | 9 |
| 2 | Probiotic metabolites from Bacillus coagulans GanedenBC30^(TM) support maturation of antigen-presenting cells in vitro显示文摘AIM:To study the effects of probiotic metabolites on maturation stage of antigen-presenting immune cells.METHODS:Ganeden Bacillus coagulans 30(GBC30) bacterial cultures in log phase were used to isolate the secreted metabolite(MET) fraction.A second fraction was made to generate a crude cell-wall-enriched fraction,by centrifugation and lysis,followed by washing.A preparation of MET was subjected to size exclusion centrifugation,generating three fractions:< 3 kDa,3-30 kDa,and 30-200 kDa and activities were tested in comparison to crude MET and cell wall in primary cultures of human peripheral blood mononuclear cell(PBMC) as a source of antigen-presenting mononuclear phagocytes.The maturation status of mononuclear phagocytes was evaluated by staining with monoclonal antibodies towards CD14,CD16,CD80 and CD86 and analyzed by flow cytometry.RESULTS:Treatment of PBMC with MET supported maturation of mononuclear phagocytes toward both macrophage and dendritic cell phenotypes.The biological activity unique to the metabolites included a reduction of CD14+ CD16+ pro-inflammatory cells,and this property was associated with the high molecular weight metabolite fraction.Changes were also seen for the dendritic cell maturation markers CD80 and CD86.On CD14dim cells,an increase in both CD80 and CD86 expression was seen,in contrast to a selective increase in CD86 expression on CD14bright cells.The co-expression of CD80 and CD86 indicates effective antigen presentation to T cells and support of T helper cell differentiation.The selective expression of CD86 in the absence of CD80 points to a role in generating T regulatory cells.CONCLUSION:The data show that a primary mechanism of action of GBC30 metabolites involves support of more mature phenotypes of antigen-presenting cells,important for immunological decision-making. | Kathleen F Benson Kimberlee A Redman Steve G Carter David Keller Sean Farmer John R Endres Gitte S Jensen | 2012 | World Journal of Gastroenterology2012，18，16： | 8 |
| 3 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 8 |
| 4 | Characterization of integrons and antibiotic resistance genes in Danish multiresistant Salmonella enterica Typhimutium DT104显示文摘 | Sandvang D Aarestrup F M Jensen L B | 1997 | FEMS Microbiol Lett1997，157，1： | 2 |
| 5 | Bayesian updating in causal probabilistic networks by local computation显示文摘 | Jensen F V Lauritzen S Olesen K | 1990 | Computational Statistics Quarterly1990，，4： | 1 |
| 6 | Analysis of associations between major histocompatibility complex( BoLA) class I haplotypes and subclinical mastitis of dairy cows显示文摘 | Jensen N E Φstergard H | 1995 | J Dairy Sci1995，78，： | 1 |
| 7 | Separation of ownership and control显示文摘 | Fama E F Jensen M | 1983 | Journal of Law and Economics1983，26，： | 1 |
| 8 | Abscisic acid inhibits type 2C protein phosphatases via the PYR/ PYL family of START proteins显示文摘 | PARK S Y FUNG P NISHIMURA N JENSEN D R FFUJII ZHAO Y LUMBA S SANTIAGO J RODRIGUES A CHOW T F | 2009 | Science2009，324，： | 1 |
| 9 | Effect of genotype, age, body weight and sex on the body composition of growing rabbits 显示文摘 | SZENDRO Z KENESSEY A JENSEN J F | 1998 | World Rabbit Science1998，6，34： | 1 |
| 10 | A luminescent oxygen channeling immuno- assay for the determination of insulin in human plasma显示文摘 | Poulsen F Jensen KB | 2007 | Biomol Screen2007，12，2： | 1 |
| 11 | Separation of Ownership and Control显示文摘 | Fama E F Jensen M C | 1983 | Journal of Law and Economics1983，26，2： | 1 |
| 12 | Use of the root contact concept,an empirical leaf conductance model and pressure-volume curves in simulating crop water relations显示文摘 | JENSEN C F SVENDSEN H ANDERSEN M N | 1993 | Plant and Soil1993，149，： | 1 |
| 13 | Bayesian Network Basics显示文摘 | Jensen F V | 1996 | AISB Quarterly (S0268-4179)1996，94，： | 1 |
| 14 | Population studies of Trichodermaharzianum and Pythium spp and biological control of damping - off and root rot of cucumber in peat following substrate amendment with oatmeal显示文摘 | Green H Jensen D F | 1992 | Bulletin Oilbsrop1992，15，1： | 1 |
| 15 | Importance of temperature, nitrate, and pH for phosphate release from aerobic sediments of four shal- low, eutrophic lakes 显示文摘 | Jensen H S Andersen F Q | 1992 | Limnology and Oceanography1992，37，3： | 1 |
| 16 | Hydraulic and chemical signals in the control of leaf expansion and stomatal conductance in soybean exposedto drought stress显示文摘 | Liu F Jensen C R Andersen M N | 2003 | Functional Plant Biol2003，30，1： | 1 |
| 17 | Agency problems and residual claims 显示文摘 | Fama E F Jensen M C | 1983 | Journal of law and Economics1983，26，2： | 1 |
| 18 | Separation of ownership and control显示文摘 | Fama E F Jensen M C | 1983 | Journal of law and economics1983，，： | 1 |
| 19 | Diversity in methane enrichments from agricultural soil revealed by DGGE separation of PCR amplified 16S rDNA fragments 显示文摘 | Jensen S Ovre~ts L Daae F L | 1998 | FEMS Microbiology Ecology1998，26，1： | 1 |
| 20 | Twenty-five years of forest recreation research in Denmark and its influence on forest policy显示文摘 | Jensen F S Koch N E | 2004 | Scandinavian Journal of Forest Research2004，19，： | 1 |
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