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| 1 | Hepatic steatosis is associated with an increased risk of carotid atherosclerosis显示文摘AIM: Although an association between helatic steatosis and vascular risk factors has been described, direct relationships between fatty liver and atherosclerosis have not yet been investigated. The aim of the present study has been to investigate those relationships.METHODS: The Study of Health in Pomerania examined a random population sample aged between 20 and 79 years.A study population of 4 222 subjects without hepatitis B and C infections and without liver cirrhosis was available for the present analysis. Hepatic steatosis was defined sonographically and intima-media thickness (IMT) as well as plaque prevalence were estimated by carotid ultrasound.RESULTS: The prevalence rate of hepatic steatosis was 29.9%. Among subjects aged ≥45 years, an association between hepatic steatosis and IMT of the carotid arteries was found in bivariate analysis, but not after adjustment for atherosclerotic risk factors. Individuals with fatty liver had more often carotid plaques than persons without fatty liver (plaque prevalence rate 76.8% vs 66.6%; P<0.001).This association persisted after adjustment for confounding factors and was predominantly present in subjects with no to mild alcohol consumption.CONCLUSION: There is an independent association between hepatic steatosis and carotid atherosclerotic plaques. Metabolic changes due to nonalcoholic fatty liver disease may explain this relationship. | Henry V(o|¨)lzke Daniel M.Robinson Volker Kleine Roland Deutscher Wolfgang Hoffmann Jan Lüdemann Ulf Schminke Christof Kessler Ulrich John | 2005 | World Journal of Gastroenterology2005，11，12： | 29 |
| 2 | 橡胶加工分析仪的应用(上)显示文摘RPA 2000橡胶加工分析仪是一种新型动态力学流变试验机,它可在未硫化和硫化两种状态分析生胶、母炼胶和混炼胶。该分析仪无需专门的试样准备,它易于操作,且能把范围广泛的动态试验条件(包括非常高的应变)作用在橡胶试样上。本文讨论RPA作为加工性能测试仪在预测不同混炼胶混炼质量方面的应用。炭黑分散效果和聚合物塑化效果,都通过RPA试验进行测定。油料添加量改变以及分段混炼技术产生的不同混炼质量则通过测量粘弹性能变化来表征。使用多种通用的轮胎胶料,鉴别出了最佳的RPA应变、频率和温度试验条件,从而可以与传统的加工对比试验之间保持最佳的相关性。本文亦给出了选定的SBR生胶的RPA粘弹特性,这些特性包括切变模量与温度的关系。这些研究涉及了不同货源乳聚物以及特种溶聚橡胶。 | John S.Dick Henry A.Pawlowski 姚琳 | 2001 | 橡塑技术与装备2001，27，1： | 23 |
| 3 | 橡胶加工分析仪的应用(下)显示文摘RPA 2000橡胶加工分析仪是一种新型动态力学流变试验机,它可在未硫化和硫化两种状态分析生胶、母胶和混炼胶。该分析仪无需专门的试样准备,它易于操作,且能把范围广泛的动态试验条件(包括非常高的应变)作用在橡胶试样上。本文讨论RPA作为加工性能测试仪在预测不同混炼胶混炼质量方面的应用。炭黑分散效果和聚合物塑化效果都通过RPA试验进行测定。油料添加量改变以及分段混炼技术产生的不同混炼质量则通过测量粘弹性能变化来表征。使用多种通用的轮胎胶料,鉴别出了最佳的RPA应变、频率和温度试验条件,从而可以与传统的加工对比试验之间保持最佳的相关性。本文亦给出了选定的SBR生胶的RPA粘弹特性,这些特性包括切变模量与温度的关系。这些研究涉及了不同货源乳聚物以及特种溶聚橡胶。 | John S.Dick Henry A.Pawlowski 姚琳译 瞿光明 | 2001 | 橡塑技术与装备2001，27，2： | 22 |
| 4 | 内侧固定平台单髁置换术后的冠状面下肢力线是翻修的影响因素显示文摘膝关节单髁置换术(unicompartmental knee arthroplasty,UKA)后患者冠状面的下肢力线被认为是影响手术长期疗效的一个重要因素,但关于最佳的UKA术后下肢力线还没有形成明确共识。一些研究主张术后下肢力线应保持在中立位,而另一些研究认为即使术后下肢力线存在10°的内翻也可获得良好的临床效果。 | Sean E Slaven John P Cody Robert A Sershon Henry Ho Robert H Hopper Jr Kevin B Fricka 李亚坤(整理) 张民(整理) | 2020 | 实用骨科杂志2020，26，12： | 15 |
| 5 | Association between thyroid function and gallstone disease显示文摘AIM: To investigate those associations using data of the population-based Study of Health in Pomerania.METHODS: A study population of 3 749 residents aged 20-79 years without previously diagnosed thyroid disease was available for analyses. Serum TSH was used to assess thyroid function. Cholelithiasis was defined by either a prior history of cholecystectomy or the presence of gallstones on ultrasound. Logistic regression was performed to analyze independent associations between thyroid function and cholelithiasis.RESULTS: There were 385 persons (10.3%) with low (<0.3 mIU/L), 3 321 persons (88.6%) with normal and 43 persons (1.2%) with high serum TSH levels (>3 mIU/L).The proportion of cholelithiasis among males and females was 14.4% and 25.3%, respectively. Among males, there was an independent relation between high serum TSH and cholelithiasis (OR 3.77; 95%-CI 1.06-13.41; ,P<0.05). zAlso among males, there was a tendency towards an elevated risk of cholelithiasis in persons with low serum TSH (OR 1.40; 95%-CI 0.96-2.02; P = 0.07). In the female population, no such relation was identified.CONCLUSION: There is an association between thyroid and gallstone disease with a gender-specific relation between hypothyroidism and cholelithiasis. | Henry Vlzke Daniel M Robinson Ulrich John | 2005 | World Journal of Gastroenterology2005，11，35： | 8 |
| 6 | Randomized controlled trial of transarterial lipiodol chemoembolization for unresectable hepatocellular carcinoma显示文摘 | Chung-Mau Lo Henry Ngan Wai-Kuen Tso Chi-Leung Liu Chi-Ming Lam Ronnie Tung-Ping Poon Sheung-Tat Fan John Wong | 2002 | Hepatology2002，，5： | 7 |
| 7 | Functional Demarcation of Active and Silent Chromatin Domains in Human HOX Loci by Noncoding RNAs显示文摘 | John L. Rinn Michael Kertesz Jordon K. Wang Sharon L. Squazzo Xiao Xu Samantha A. Brugmann L. Henry Goodnough Jill A. Helms Peggy J. Farnham Eran Segal Howard Y. Chang | 2007 | Cell2007，，7： | 6 |
| 8 | 关于与青光眼疾病严重性相关的资源使用和成本的一项多中心回顾性试验研究显示文摘目的:调查在不同疾病严重程度上青光眼治疗的资源消耗和直接成本。
设计:基于医学档案综述的观察性、回顾性的队列研究。 | Paul P. Lee John G. Walt John J. Doyle Sameer V. Kotak Stacy J. Evans Donald L. Budenz Philip P. Chen Anne L. Coleman Robert M. Feldman HenRY D. Jampel L.Jay Katz Richard P.Mills Jonathan S.Myers Robert J.Noecker Jody R.Piltz-Seymour Robert R.Ritch Paul N.Schacknow Janet B.Serle Gary L.Trick 范翔(译) | 2006 | 美国医学会眼科杂志(中文版)2006，18，4： | 4 |
| 9 | Normalised intrinsic mortality risk in liver transplantation: European Liver Transplant Registry study显示文摘 | René Adam Valérie Cailliez Pietro Majno Vincent Karam Paul McMaster Roy Y Calne John O’Grady Rudolf Pichlmayr Peter Neuhaus Jean-Bernard Otte Krister Hoeckerstedt Henri Bismuth | 2000 | The Lancet . 2000 (9230)2000，，9230： | 3 |
| 10 | Surgical Management of Bile Duct Injuries Sustained During Laparoscopic Cholecystectomy: Perioperative Results in 200 Patients显示文摘 | Jason K. Sicklick Melissa S. Camp Keith D. Lillemoe Genevieve B. Melton Charles J. Yeo Kurtis A. Campbell Mark A. Talamini Henry A. Pitt JoAnn Coleman Patricia A. Sauter John L. Cameron | 2005 | Annals of Surgery2005，，5： | 3 |
| 11 | Role of EUS for preoperative evaluation of cholangiocarcinoma: a large single-center experience显示文摘 | Mehdi Mohamadnejad John M. DeWitt Stuart Sherman Julia K. LeBlanc Henry A. Pitt Michael G. House Kelly J. Jones Evan L. Fogel Lee McHenry James L. Watkins Gregory A. Cote Glen A. Lehman Mohammad A. Al-Haddad | 2011 | Gastrointestinal Endoscopy2011，，1： | 3 |
| 12 | Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock显示文摘 | R. Phillip Dellinger Jean M. Carlet Henry Masur Herwig Gerlach Thierry Calandra Jonathan Cohen Juan Gea-Banacloche Didier Keh John C. Marshall Margaret M. Parker Graham Ramsay Janice L. Zimmerman Jean-Louis Vincent M. M. Levy | 2004 | Intensive Care Medicine2004，，4： | 3 |
| 13 | Equity ownership and the two faces of debt显示文摘 | John J. McConnell Henri Servaes | 1995 | Journal of Financial Economics1995，，1： | 3 |
| 14 | Cholangiocarcinoma: A Spectrum of Intrahepatic, Perihilar, and Distal Tumors显示文摘 | Attila Nakeeb Henry A. Pitt Taylor A. Sohn JoAnn Coleman Ross A. Abrams Steven Piantadosi Ralph H. Hruban Keith D. Lillemoe Charles J. Yeo John L. Cameron | 1996 | Annals of Surgery1996，，4： | 3 |
| 15 | Weight and Type 2 Diabetes after Bariatric Surgery: Systematic Review and Meta-analysis显示文摘 | Henry Buchwald Rhonda Estok Kyle Fahrbach Deirdre Banel Michael D. Jensen Walter J. Pories John P. Bantle Isabella Sledge | 2009 | The American Journal of Medicine2009，，3： | 2 |
| 16 | Comparison of Hybrid Coronary Revascularization Versus Coronary Artery Bypass Grafting in Patients ≥65 Years With Multivessel Coronary Artery Disease显示文摘 | Ralf E. Harskamp John D. Puskas Jan G. Tijssen Patrick F. Walker Henry A. Liberman Renato D. Lopes Thomas A. Vassiliades Eric D. Peterson Michael E. Halkos | 2014 | The American Journal of Cardiology2014，，： | 2 |
| 17 | Outcomes of combination MRI-targeted and transperineal template biopsy in restaging low-risk prostate cancer for active surveillance显示文摘Objective:Active surveillance(AS)offers a strategy to reduce overtreatment and now is a widely accepted treatment option for low-risk prostate cancer.An ideal tool for risk-stratification would detect aggressive cancers and exclude such men from taking up AS in the first place.We evaluate if a combination of transperineal template biopsy with magnetic resonance imaging(MRI)-targeted biopsy identifies significant prostate cancer amongst men initially diagnosed with low-risk prostate cancer.Methods:This prospective,single-blinded study included men with low-risk prostate cancer(D’Amico’s Criteria)diagnosed on conventional transrectal ultrasound-guided biopsy.Patients first underwent multiparametric MRI of the prostate6 weeks after initial biopsy.Each suspicious lesion is mapped and assigned a Prostate Imaging Reporting and Data System(PIRADS)score.Template biopsy is first performed with the surgeon blinded to MRI findings followed by MRI-targeted biopsy using a robotic transperineal biopsy platform.Results:The age of the 19 men included is 65.4±4.9 years(mean±SD).Prostate specific antigen(PSA)at diagnosis and at the time of transperineal biopsy were comparable(7.3±1.7 ng/mL and 7.0±1.8 ng/mL,p Z 0.67),so were prostate volumes(34.2±8.9 mL and 32.1±13.4 mL,p Z 0.28).MRI-targeted biopsy had a higher percentage of cancer detection per core compared to template biopsy(11.7%vs.6.5%,p Z 0.02),this was more than 3 times superior for Gleason 7 disease(5.9%vs.1.6%,p<0.01).Four of 18(22.2%)patients with MRI lesions had significant disease with MRI-targeted biopsy alone.Three of 19 patients(15.8%)had significant disease with template biopsy alone.In combination,both techniques upclassified five patients(26.3%),all of whom underwent radical prostatectomy.Whole mount histology confirmed tumour location and grade.All six patients with PIRADS 5 lesions had cancer detected(66.6%significant disease).Conclusion:A combination of MRI-targeted and template biopsy may optimally risk-classify“low-risk”patients diagnosed on initial conventional transrectal ultrasonography(TRUS)prostate biopsy. | Kenneth Chen Kae Jack Tay Yan Mee Law Hakan Aydin Henry Ho Christopher Cheng John Shyi Peng Yuen | 2018 | Asian Journal of Urology2018，5，3： | 2 |
| 18 | The Role of Synthetic Biology in Atmospheric Greenhouse Gas Reduction: Prospects and Challenges显示文摘The long atmospheric residence time of CO2 creates an urgent need to add atmospheric carbon drawdown to CO2 regulatory strategies.Synthetic and systems biology(SSB),which enables manipulation of cellular phenotypes,offers a powerful approach to amplifying and adding new possibilities to current land management practices aimed at reducing atmospheric carbon.The participants(in attendance:Christina Agapakis,George Annas,Adam Arkin,George Church,Robert Cook-Deegan,Charles DeLisi,Dan Drell,Sheldon Glashow,Steve Hamburg,Henry Jacoby,Henry Kelly,Mark Kon,Todd Kuiken,Mary Lidstrom,Mike MacCracken,June Medford,Jerry Melillo,Ron Milo,Pilar Ossorio,Ari Patrinos,Keith Paustian,Kristala Jones Prather,Kent Redford,David Resnik,John Reilly,Richard J.Roberts,Daniel Segre,Susan Solomon,Elizabeth Strychalski,Chris Voigt,Dominic Woolf,Stan Wullschleger,and Xiaohan Yang)identified a range of possibilities by which SSB might help reduce greenhouse gas concentrations and which might also contribute to environmental sustainability and adaptation.These include,among other possibilities,engineering plants to convert CO2 produced by respiration into a stable carbonate,designing plants with an increased root-to-shoot ratio,and creating plants with the ability to self-fertilize.A number of serious ecological and societal challenges must,however,be confronted and resolved before any such application can be fully assessed,realized,and deployed. | Charles DeLisi Aristides Patrinos Michael MacCracken Dan Drell George Annas Adam Arkin George Church Robert Cook-Deegan Henry Jacoby Mary Lidstrom Jerry Melillo Ron Milo Keith Paustian John Reilly Richard J.Roberts Daniel Segrè Susan Solomon Dominic Woolf Stan D.Wullschleger Xiaohan Yang | 2020 | BioDesign Research2020，，1： | 2 |
| 19 | Hypoglycemia and Diabetes: A Report of a Workgroup of the American Diabetes Association and The Endocrine Society显示文摘 | Elizabeth R. Seaquist John Anderson Belinda Childs Philip Cryer Samuel Dagogo-Jack Lisa Fish Simon R. Heller Henry Rodriguez James Rosenzweig Robert Vigersky | 2013 | The Journal of Clinical Endocrinology & Metabolism2013，，5： | 2 |
| 20 | Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock显示文摘 | R. Phillip Dellinger Jean M. Carlet Henry Masur Herwig Gerlach Thierry Calandra Jonathan Cohen Juan Gea-Banacloche Didier Keh John C. Marshall Margaret M. Parker Graham Ramsay Janice L. Zimmerman Jean-Louis Vincent Mitchell M. Levy | 2004 | Critical Care Medicine2004，，3： | 2 |
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