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| 1 | 美国临床肿瘤学会IV期非小细胞肺癌化疗的临床实践指南更新显示文摘本文旨在为IV期非小细胞肺癌患者的治疗提供更新版推荐。本文资料检索源自2002年以来公布的相关随机试验文献。此指南范围限于化疗与生物治疗。更新委员会对这些文献进行了总结并提供了推荐更新。162篇文献符合标准被纳入参考。本推荐基于可改善总生存期的治疗方法。仅改善无进展生存期的治疗方法推动了对毒性及生存质量的监测。对于体力状态评分为0分或1分患者的一线治疗,可推荐以铂类为基础的细胞毒性药物的两药联用。对铂类治疗有禁忌的患者,可采用非铂类细胞毒性两药联合。对于体力状态评分为2分的患者,单一细胞毒性药物即可。对于疾病进展或经过4个周期的治疗仍对治疗无反应的患者,应停止一线细胞毒性化疗。即使在6个周期后患者对治疗仍有反应,亦应停止两药细胞毒性化疗。对于伴有明确的表皮生长因子受体(epidermal growth factor receptor,EGFR)突变的患者,可推荐一线采用吉非替尼治疗;对于EGFR突变为阴性或不明确的患者,细胞毒性化疗更佳。除具有特定临床特征的患者外,可推荐贝伐单抗与卡铂-紫杉醇联用。对于通过免疫组化证实EGFR阳性的肿瘤患者,可推荐西妥昔单抗与顺铂-长春瑞滨联用。多西紫杉醇、厄洛替尼、吉非替尼或培美曲塞被推荐作为二线治疗。对于未曾接受过厄洛替尼或吉非替尼治疗的患者,可推荐厄洛替尼作为三线治疗。现有数据不足以推荐常规三线采用细胞毒性药物。已有的证据也不足以推荐常规应用分子标记物选择化疗。 | Christopher G. AZZOLI Sherman Baker JR Sarah TEMIN William PAO Timothy ALIFF Julie BRAHMER David H. JOHNSON Janessa L. LASKIN Gregory MASTERS Daniel MILTON Luke NORDQUIST David G. PFISTER Steven PIANTADOSI Joan H. SCHILLER Reily SMITH Thomas J. SMITH John R. STRAWN David TRENT Giuseppe GIACCONE 丁燕(翻译) 南娟(翻译) 刘谦(翻译) 周清华(校对) 陈军(校对) | 2010 | 中国肺癌杂志2010,13,3: | 43 |
| 2 | Screening and Surveillance for the Early Detection of Colorectal Cancer and Adenomatous Polyps, 2008: A Joint Guideline From the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology显示文摘 | Bernard Levin David A. Lieberman Beth McFarland Kimberly S. Andrews Durado Brooks John Bond Chiranjeev Dash Francis M. Giardiello Seth Glick David Johnson C. Daniel Johnson Theodore R. Levin Perry J. Pickhardt Douglas K. Rex Robert A. Smith Alan Thorson S | 2008 | Gastroenterology2008,,5: | 8 |
| 3 | Is There a Pathogenetic Role for Uric Acid in Hypertension and Cardiovascular and Renal Disease?显示文摘 | Richard J. Johnson Duk-Hee Kang Daniel Feig Salah Kivlighn John Kanellis Susumu Watanabe Katherine R. Tuttle Bernardo Rodriguez-Iturbe Jaime Herrera-Acosta Marilda Mazzali | 2003 | Hypertension: Journal of the American Heart Association2003,,6: | 4 |
| 4 | Colorectal cancer screening and surveillance: Clinical guidelines and rationale—Update based on new evidence显示文摘 | Sidney Winawer Robert Fletcher Douglas Rex John Bond Randall Burt Joseph Ferrucci Theodore Ganiats Theodore Levin Steven Woolf David Johnson Lynne Kirk Scott Litin Clifford Simmang | 2003 | Gastroenterology2003,,2: | 4 |
| 5 | The Endothelial-Specific MicroRNA miR-126 Governs Vascular Integrity and Angiogenesis显示文摘 | Shusheng Wang Arin B. Aurora Brett A. Johnson Xiaoxia Qi John McAnally Joseph A. Hill James A. Richardson Rhonda Bassel-Duby Eric N. Olson | 2008 | Developmental Cell2008,,2: | 4 |
| 6 | Quality in the technical performance of colonoscopy and the continuous quality improvement process for colonoscopy: recommendations of the U.S. Multi-Society Task Force on Colorectal Cancer显示文摘 | Douglas K Rex John H Bond Sidney Winawer Theodore R Levin Randall W Burt David A Johnson Lynne M Kirk Scott Litlin David A Lieberman Jerome D Waye James Church John B Marshall Robert H Riddell | 2002 | The American Journal of Gastroenterology2002,,6: | 3 |
| 7 | TEAMS IN ORGANIZATIONS: From Input-Process-Output Models to IMOI Models显示文摘 | Daniel R. Ilgen John R. Hollenbeck Michael Johnson Dustin Jundt | 2005 | Annual Review of Psychology2005,,: | 3 |
| 8 | Development and optimization of thermal contrast amplification lateral flow immunoassays for ultrasensitive HIV p24 protein detection显示文摘Detection of human immunodeficiency virus(HIV)p24 protein at a single pg/ml concentration in point-of-care(POC)settings is important because it can facilitate acute HIV infection diagnosis with a detection sensitivity approaching that of laboratory-based assays.However,the limit of detection(LOD)of lateral flow immunoassays(LFAs),the most prominent POC diagnostic platform,falls short of that of laboratory protein detection methods such as enzyme-linked immunosorbent assay(ELISA).Here,we report the development and optimization of a thermal contrast amplification(TCA)LFA that will allow ultrasensitive detection of 8 pg/ml p24 protein spiked into human serum at POC,approaching the LOD of a laboratory test.To achieve this aim,we pursued several innovations as follows:(a)defining a new quantitative figure of merit for LFA design based on the specific to nonspecific binding ratio(BR);(b)using different sizes and shapes of gold nanoparticles(GNPs)in the systematic optimization of TCA LFA designs;and(c)exploring new laser wavelengths and power regimes for TCA LFA designs.First,we optimized the blocking buffer for the membrane and running buffer by quantitatively measuring the BR using a TCA reader.The TCA reader interprets the thermal signal(i.e.,temperature)of GNPs within the membrane when irradiated by a laser at the plasmon resonance wavelength of the particle.This process results in higher detection and quantitation of GNPs than in traditional visual detection(i.e.,color intensity).Further,we investigated the effect of laser power(30,100,200 mW),GNP size and shape(30 and 100 nm gold spheres,150 nm gold-silica shells),and laser wavelength(532,800 nm).Applying these innovations to a new TCA LFA design,we demonstrated that 100nm spheres with a 100 mW 532 nm laser provided the best performance(i.e.,LOD=8pg/ml).This LOD is significantly better than that of the current colorimetric LFA and is in the range of the laboratory-based p24 ELISA.In summary,this TCA LFA for p24 protein shows promise for detecting acute HIV infection in POC settings. | Li Zhan Timothy Granade Yilin Liu Xierong Wei Ae Youngpairoj Vickie Sullivan Jeff Johnson John Bischof | 2020 | Microsystems & Nanoengineering2020,6,1: | 3 |
| 9 | Expression of Transforming Growth Factor-β1 by Pancreatic Stellate Cells and Its Implications for Matrix Secretion and Turnover in Chronic Pancreatitis显示文摘 | Fanny Wai-Tsing Shek Robert Christopher Benyon Fiona Mairi Walker Peter Raymond McCrudden Sylvia Lin Foon Pender Elizabeth Jean Williams Penelope Ann Johnson Colin David Johnson Adrian Calvin Bateman David Roger Fine John Peter Iredale | 2002 | The American Journal of Pathology2002,,5: | 2 |
| 10 | 2013 ACCF/AHA Guideline for the Management of Heart Failure: Executive Summary: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines显示文摘 | Clyde W. Yancy Mariell Jessup Biykem Bozkurt Javed Butler Donald E. Casey Mark H. Drazner Gregg C. Fonarow Stephen A. Geraci Tamara Horwich James L. Januzzi Maryl R. Johnson Edward K. Kasper Wayne C. Levy Frederick A. Masoudi Patrick E. McBride John J.V. | 2013 | Circulation2013,,16: | 2 |
| 11 | Outcome After Colectomy for Clostridium Difficile Colitis显示文摘 | Walter E. Longo M.D. John E. Mazuski M.D. Katherine S. Virgo Ph.D. Paul Lee M.D. Anil N. Bahadursingh M.D. Frank E. Johnson M.D | 2004 | Diseases of the Colon & Rectum2004,,10: | 2 |
| 12 | Uric Acid Stimulates Monocyte Chemoattractant Protein-1 Production in Vascular Smooth Muscle Cells Via Mitogen-Activated Protein Kinase and Cyclooxygenase-2显示文摘 | John Kanellis Susumu Watanabe Jin H. Li Duk Hee Kang Ping Li Takahiko Nakagawa Ann Wamsley David Sheikh-Hamad Hui Y. Lan Lili Feng Richard J. Johnson | 2003 | Hypertension: Journal of the American Heart Association2003,,6: | 2 |
| 13 | Comparison of Central and Extended Left Pancreatectomy for Lesions of the Pancreatic Neck显示文摘 | Lee M. Ocuin MD Juan M. Sarmiento MD Charles A. Staley MD John R. Galloway MD Colin D. Johnson MD William C. Wood MD David A. Kooby MD | 2008 | Annals of Surgical Oncology2008,,8: | 2 |
| 14 | The Endothelial-Specific MicroRNA miR-126 Governs Vascular Integrity and Angiogenesis显示文摘 | Shusheng Wang Arin B. Aurora Brett A. Johnson Xiaoxia Qi John McAnally Joseph A. Hill James A. Richardson Rhonda Bassel-Duby Eric N. Olson | 2008 | Developmental Cell2008,,2: | 2 |
| 15 | The Surgical and Medical Perioperative Complications of Anterior Spinal Fusion Surgery in the Thoracic and Lumbar Spine in Adults: A Review of 1223 Procedures显示文摘 | Tom Faciszewski Robert B. Winter John E. Lonstein Francis Denis Linda Johnson | 1995 | Spine1995,,14: | 2 |
| 16 | Preferences for self-management support: Findings from a survey of diabetes patients in safety-net health systems显示文摘 | Urmimala Sarkar John D. Piette Ralph Gonzales Daniel Lessler Lisa D. Chew Brendan Reilly Jolene Johnson Melanie Brunt Jennifer Huang Marsha Regenstein Dean Schillinger | 2007 | Patient Education and Counseling2007,,1: | 1 |
| 17 | Acoustic and optical borehole-wall imaging for fractured-rock aquifer studies显示文摘 | John H. Williams Carole D. Johnson | 2003 | Journal of Applied Geophysics2003,,1: | 1 |
| 18 | Rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone in patients with newly diagnosed diffuse large B-cell non-Hodgkin lymphoma: a phase 3 comparison of dose intensification with 14-day versus 21-day cycles显示文摘 | David Cunningham Eliza A Hawkes Andrew Jack Wendi Qian Paul Smith Paul Mouncey Christopher Pocock Kirit M Ardeshna John A Radford Andrew McMillan John Davies Deborah Turner Anton Kruger Peter Johnson Joanna Gambell David Linch | 2013 | The Lancet2013,,9880: | 1 |
| 19 | The Significance of 'Indefinite for Dysplasia' Grading in Barrett Metaplasia显示文摘 | Younes Mamoun Lauwers Gregory Y Ertan Atilla Ergun Gulchin Verm Ray Bridges Margaret Woods Karen Meriano Frank Schmulen Carl Johnson Craig Barroso Alberto Schwartz Jim McKechnie John Lechago Juan | 2011 | Archives of Pathology & Laboratory Medicine2011,,: | 1 |
| 20 | Sorption of 17 β -estradiol onto selected soil minerals显示文摘 | Tristan Van Emmerik Michael J. Angove Bruce B. Johnson John D. Wells Milena B. Fernandes | 2003 | Journal of Colloid And Interface Science2003,,1: | 1 |