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| 1 | Immunotherapy for hepatocellular carcinoma:Current and future显示文摘Hepatocellular carcinoma(HCC)arises on the background of chronic liver disease.Despite the development of effective anti-viral therapeutics HCC is continuing to rise,in part driven by the epidemic of non-alcoholic fatty liver disease.Many patients present with advanced disease out with the criteria for transplant,resection or even locoregional therapy.Currently available therapeutics for HCC are effective in a small minority of individuals.However,there has been a major global interest in immunotherapies for cancer and although HCC has lagged behind other cancers,great opportunities now exist for treating HCC with newer and more sophisticated agents.Whilst checkpoint inhibitors are at the forefront of this revolution,other therapeutics such as inhibitory cytokine blockade,oncolytic viruses,adoptive cellular therapies and vaccines are emerging.Broadly these may be categorized as either boosting existing immune response or stimulating de novo immune response.Although some of these agents have shown promising results as monotherapy in early phase trials it may well be that their future role will be as combination therapy,either in combination with one another or in combination with treatment modalities such as locoregional therapy.Together these agents are likely to generate new and exciting opportunities for treating HCC,which are summarized in this review. | Michael P Johnston Salim I Khakoo | 2019 | World Journal of Gastroenterology2019，25，24： | 23 |
| 2 | 骨髓活检标本中经典型霍奇金淋巴瘤的诊断显示文摘经典型霍奇金淋巴瘤(CHL)是一种通常发生于淋巴结的B细胞肿瘤,具有扩散到结外的潜能,可累及几乎任何器官系统,如肺、肝、骨和骨髓。原发结外CHL不常见,原发骨髓累及的CHL更为罕见(0.25%),其通常发生于HIV阳性患者且通常与EBV相关。 | Laurent C Arber D A Johnston P 陈敏(译) 刘勇(审校) | 2021 | 临床与实验病理学杂志2021，37，4： | 2 |
| 3 | Differential pharmacokinetics of digoxin in elderly patients 显示文摘 | Hanratty CG McGlinchey P Johnston GD | 2000 | Drugs Aging2000，17，5： | 1 |
| 4 | Phospholipid - stabilized nanoparticles of cyclosporine A by rapid expansion from supercritical to aqueous solution显示文摘 | YOUNG T J JOHNSTON K P PACE G W | 2004 | AAPS Pharm Sci Tech2004，5，1： | 1 |
| 5 | Variation in color between intended matched shade and fabricated shade of dental porcelain显示文摘 | Monaghan P Johnston WM | 2002 | J Prosthet Dent2002，87，6： | 1 |
| 6 | Synergistic interaction between paclitaxel and 8-clloro-adenosine 3',5'-monophosphate in human ovavian carcinoma cell lines显示文摘 | Johnston P G | 1999 | Clin Cancer Res1999，5，1： | 1 |
| 7 | Flow-based multiadsorbate ellipsometric porosimetry for the characterization of mesoporous Pt- TiO2 and Au-TiO2 nanocomposites显示文摘 | May R A Patel M N Johnston K P | 2009 | Langmuir2009，25，8： | 1 |
| 8 | Vapor-absent melting at 10 kbar of a biotite- and amphibole-bearing tonalitic gneiss: implication for the generation of A-type granites显示文摘 | Skjerlie K P Johnston A D | 1992 | Geology1992，20，： | 1 |
| 9 | A Phase II trial of the oral mTOR inhibitor everolimus in relapsed Hodgkin lymphoma显示文摘 | Johnston P B Inwards D J Colgan J P | 2010 | Am JHematol2010，85，5： | 1 |
| 10 | Bile acid and lysolecithin concentration in the stomach of patients with gastric ulcer显示文摘 | Dewar P King R Johnston D | 1983 | Br Jsurg1983，73，： | 1 |
| 11 | PCR as a Confirmatory Technique for Laboratory Diagnosis of Ma- laria显示文摘 | Stephanie P Johnston Norman J Pieniazek Maniphet V Xayavong | 2006 | J Clin Microbiol2006，44，3： | 1 |
| 12 | Are short femoral nails superior to the sliding hip screw A meta-analysis of 24 studies involving 3279 fractures显示文摘 | Jones HW Johnston P Parker M | | 0，，： | 1 |
| 13 | Empirical functional and efficient smoothing parameter selection (with discussion) 显示文摘 | Hall P Johnstone I | 1992 | Journal of the Royal Statistical Society Series B1992，54，2： | 1 |
| 14 | Total water-solu- ble sugars quantificaton in bio-oil using the phenol-sulfuric acid assay显示文摘 | Rover M R Johnston P A Buddhi P | 2013 | JAnal Appl Pyrol2013，104，2： | 1 |
| 15 | Beyond Vertical Integration :The Rise of the Value-added Partnership显示文摘 | R Johnston & P Lawrence | 1988 | Harvard Business Review1988，66，4： | 1 |
| 16 | Community study of role of viral infections in exacerbations of asthma in 9-11 year old children显示文摘 | Pattemore P K Sanderson G | 1995 | BMJ1995，310，6898： | 1 |
| 17 | Pilot casestudy of the therapeutic potential of hyperbaric oxygentherapy on chronic brain injury 显示文摘 | Hardy P Johnston KM de Beaumont L | 2007 | J Neurol Scl2007，253，12： | 1 |
| 18 | Con- genital adrenal hyperplasia due to 21-hydroxylase deficien- cy: alterations in cortisol pharmacokinetics at puberty显示文摘 | Charmandari E Hindmarsh P C Johnston A | 2001 | J Clin Endocrinol Metab2001，86，6： | 1 |
| 19 | 5- Hydroperoxycarbonylphthalimide: a new reagent for expoxidation显示文摘 | James Alum P Johnstone Robert A W Mc Carron Moya | 1998 | Chem Commun (Cambridge)1998，，3： | 1 |
| 20 | A perpetual cascade of cytokines postirradiation leads to pulmonary fibrosis显示文摘 | RUBIN P JOHNSTON C J WILLIAMS J P | 1995 | Int J Radiat Oncol Biol Phys1995，33，1： | 1 |
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