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| 1 | Factors associated with time to laparoscopic cholecystectomy for acute cholecystitis显示文摘AIM: To determine patient and process of care factors associated with performance of timely laparoscopic cholecystectomy for acute cholecystitis. METHODS: A retrospective medical record review of 88 consecutive patients with acute cholecystitis was conducted. Data collected included demographic data, co-morbidities, symptoms and physical findings at presentation, laboratory and radiological investigations, length of stay, complications, and admission service (medical or surgical). Patients not undergoing cholecystectomy during this hospitalization were excluded from analysis. Hierarchical generalized linear models were constructed to assess the association of pre-operative diagnostic procedures, presenting signs, and admitting service with time to surgery.RESULTS: Seventy cases met inclusion and exclusion criteria, among which 12 were admitted to the medical service and 58 to the surgical service. Mean ± SD time to surgery was 39.3 ± 43 h, with 87% of operations performed within 72 h of hospital arrival. In the adjusted models, longer time to surgery was associated with number of diagnostic studies and endoscopic retrograde cholangio-pancreatography (ERCP, P = 0.01) as well with admission to medical service without adjustment for ERCP (P < 0.05). Patients undergoing both magnetic resonance cholangiopancreatography (MRCP) and computed tomography (CT) scans experienced the longest waits for surgery. Patients admitted to the surgical versus medical service underwent surgery earlier (30.4 ± 34.9 vs 82.7 ± 55.1 h, P < 0.01), had less post-operative complications (12% vs 58%, P < 0.01), and shorter length of stay (4.3 ± 3.4 vs 8.1 ± 5.2 d, P < 0.01).CONCLUSION: Admission to the medical service and performance of numerous diagnostic procedures, ERCP, or MRCP combined with CT scan were associated with longer time to surgery. Expeditious performance of ERCP and MRCP and admission of medically stable patients with suspected cholecystitis to the surgical service to speed up time to surgery should be considered. | Chris N Daniak David Peretz Jonathan M Fine Yun Wang Alan K Meinke William B Hale | 2008 | World Journal of Gastroenterology2008,14,7: | 13 |
| 2 | Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial显示文摘 | Paul Y Kwo Eric J Lawitz Jonathan McCone Eugene R Schiff John M Vierling David Pound Mitchell N Davis Joseph S Galati Stuart C Gordon Natarajan Ravendhran Lorenzo Rossaro Frank H Anderson Ira M Jacobson Raymond Rubin Kenneth Koury Lisa D Pedicone Clifford | 2010 | The Lancet2010,,9742: | 3 |
| 3 | Interplay between the cardiac rennin angiotensin system and JAKSTAT signaling: role in ca-rdiac hypertrophy, ischemia/repe fusion dysfunction, and heart failure 显示文摘 | Jonathan N E Day Kenneth M Baker | 2002 | J Mol Cell Cardiol2002,34,11: | 1 |
| 4 | A common genetic basis in sweet corn inbred cr1 for cross sensitivi- ty to multiple cytochrome P450-metabolized herbicides 显示文摘 | Jonathan N N Martin M Williams I I | 2008 | Weed Science2008,56,: | 1 |
| 5 | Side resistance of large diameter bored piles socketed into decomposed rock显示文摘 | Charles W W N Terence L Y Y Jonathan H M L | 2001 | Journal of Geotechnical and Geoenvironmental Engineering ASCE2001,127,8: | 1 |
| 6 | Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial显示文摘 | Stephen M Davis Geoffrey A Donnan Mark W Parsons Christopher Levi Kenneth S Butcher Andre Peeters P Alan Barber Christopher Bladin Deidre A De Silva Graham Byrnes Jonathan B Chalk John N Fink Thomas E Kimber David Schultz Peter J Hand Judith Frayne Graeme | 2008 | Lancet Neurology2008,,4: | 1 |
| 7 | A common genetic basis in sweet corn in- bred Crl for cross sensitivity to multiple cytochrome P450-metabo- lized herbicides显示文摘 | Jonathan N N Martin M W | 2008 | Weed Science2008,56,: | 1 |
| 8 | A high-resolution model of soil and surface water conditions显示文摘 | ILYA M D MACLEA N JONATHAN J | 2012 | Ecological Modelling2012,23,7: | 1 |
| 9 | Gaussian-mixture-modelbased Spatial Neighborhood Relationships for Pixel Labeling Problem显示文摘 | Thanh M N Jonathan Q M | 2012 | IEEE Transactions on Systems Man and Cybernetics Part B:Cybernetics2012,42,1: | 1 |
| 10 | Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial显示文摘 | Paul Y Kwo Eric J Lawitz Jonathan McCone Eugene R Schiff John M Vierling David Pound Mitchell N Davis Joseph S Galati Stuart C Gordon Natarajan Ravendhran Lorenzo Rossaro Frank H Anderson Ira M Jacobson Raymond Rubin Kenneth Koury Lisa D Pedicone Clifford | 2010 | The Lancet2010,,9742: | 1 |
| 11 | The specificity and affinity of immunoliposome targeting to oral bactceria显示文摘 | Anne M R Jonathan E G Malcolm N J | 1998 | Biochimica et Biophysica Acta1998,1369,: | 1 |
| 12 | Three - dimensional carbon dioxide - induced strain distribution within a confined bituminous coal显示文摘 | J Denis N Pone Michael Hile Phillip M Halleck Jonathan P Mathews | 2009 | Intemati - onal Journal of Coal Geology2009,77,10: | 1 |
| 13 | A self-organising network that grows when required显示文摘 | STEPHEN M JONATHAN S ULRICH N | 2002 | Neural Networks2002,15,89: | 1 |
| 14 | Pancreatic sphincterotomy:Technique,indications,and complications显示文摘Pancreatic sphincterotomy serves as the cornerstone of endoscopic therapy of the pancreas. Historically, its indications have been less well-defined than those of endoscopic biliary sphincterotomy, yet it plays a definite and useful role in diseases such as chronic pancreatitis and pancreatic-type sphincter of Oddi dysfunction. In the appropriate setting, it may be used as a single therapeutic maneuver, or in conjunction with other endoscopic techniques such as pancreatic stone extraction or stent placement. The current standard of practice utilizes two different methods of performing pancreatic sphincterotomy: a pull-type sphincterotome technique without prior stent placement, and a needle-knife sphincterotome technique over an existing stent. The complications associated with pancreatic sphincterotomy are many, although acute pancreatitis appears to be the most common and the most serious of the early complications. As such, it continues to be reserved for those endoscopists who perform a relatively high-volume of therapeutic pancreaticobiliary endoscopic retrograde cholangio-pancreatography. | Jonathan M Buscaglia Anthony N Kalloo | 2007 | World Journal of Gastroenterology2007,13,30: | 1 |
| 15 | Data and methods for estimating the severity of minor impacts 显示文摘 | Mark N B Bing C W Jonathan M L | 1995 | SAE Transaction1995,104,6: | 1 |
| 16 | Comparing high and low residential density: life cycle analysis of energy use and greenhnuse gas emissions 显示文摘 | Jonathan N Heather L M | 2006 | Journey of Urban Planning and Development2006,,3: | 1 |
| 17 | Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial显示文摘 | Paul Y Kwo Eric J Lawitz Jonathan McCone Eugene R Schiff John M Vierling David Pound Mitchell N Davis Joseph S Galati Stuart C Gordon Natarajan Ravendhran Lorenzo Rossaro Frank H Anderson Ira M Jacobson Raymond Rubin Kenneth Koury Lisa D Pedicone Clifford | 2010 | The Lancet2010,,9742: | 1 |
| 18 | Strong expre ssion of vascular permeability factor/vascular endothelial growth facor and its receptors in ovarian borderline and malingant neoplasms显示文摘 | James D Jonathan N | 1996 | Gancer Lett1996,74,6: | 1 |
| 19 | Difference in Treatment Outcome in Outpatients With Anxious Versus Nonanxious Depression: A STAR*D Report显示文摘 | Fava Maurizio Rush A John Alpert Jonathan E Balasubramani G K Wisniewski Stephen R Carmin Cheryl N Biggs Melanie M Zisook Sidney Leuchter Andrew Howland Robert Warden Diane Trivedi Madhukar H | 2008 | The American Journal of Psychiatry2008,,3: | 1 |
| 20 | Side resistance of large diameter piles socketed into decomposed rocks显示文摘 | CHARLES W W N TERENCE L Y Y JONATHAN H M L | 2001 | Journal of Geotechnical and Geoenvironmental Engineering2001,127,8: | 1 |