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| 1 | Endoscopic balloon catheter dilatation via retrograde or static technique is safe and effective for cricopharyngeal dysfunction显示文摘AIM To evaluate the safety and efficacy of upper esophageal sphincter(UES) dilatation for cricopharyngeal(CP) dysfunction. To determine if:(1) indication for dilatation; or(2) technique of dilatation correlated with symptom improvement.METHODS All balloon dilatations performed at our institution from over a 3-year period were retrospectively analyzed for demographics, indication and dilatation site. All dilatations involving the UES underwent further review to determine efficacy, complications, and factors that predict success. Dilatation technique was separated into static(stationary balloon distention) and retrograde(brusque pull-back of a fully distended balloon across the UES).RESULTS Four hundred and eighty-eight dilatations were reviewed. Thirty-one patients were identified who underwent UES dilatation. Median age was 63 years(range 27-81)and 55% of patients were male. Indications included dysphagia(28 patients), globus sensation with evidence of UES dysfunction(2 patients) and obstruction to echocardiography probe with cricopharyngeal(CP)bar(1 patient). There was evidence of concurrent oropharyngeal dysfunction in 16 patients(52%) and a small Zenker's diverticula(≤ 2 cm) in 7 patients(23%). Dilator size ranged from 15 mm to 20 mm. Of the 31 patients, 11 had dilatation of other esophageal segments concurrently with UES dilatation and 20 had UES dilatation alone.Follow-up was available for 24 patients for a median of 2.5 mo(interquartile range 1-10 mo), of whom 19 reported symptomatic improvement(79%). For patients undergoing UES dilatation alone, follow-up was available for 15 patients, 12 of whom reported improvement(80%).Nineteen patients underwent retrograde dilatation(84%response) while 5 patients had static dilatation(60%response); however, there was no significant difference in symptom improvement between the techniques(P = 0.5).Successful symptom resolution was also not significantly affected by dilator size, oropharyngeal dysfunction,Zenker's diverticulum, age or gender(P > 0.05). The only complication noted was uvular edema and a shallow ulcer after static dilatation in one patient, which resolved spontaneously and did not require hospital admission.CONCLUSION UES dilatation with a through-the-scope balloon by either static or retrograde technique is safe and effective for the treatment of dysphagia due to CP dysfunction. To our knowledge, this is the first study evaluating retrograde balloon dilatation of the UES. | Vinay Chandrasekhara Joyce Koh Lakshmi Lattimer Kerry B Dunbar William J Ravich John O Clarke | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，4： | 6 |
| 2 | Current concepts in total femoral replacement显示文摘Total femoral replacement(TFR) is a salvage arthroplasty procedure used as an alternative to lower limb amputation. Since its initial description in the mid-20^(th) century, this procedure has been used in a variety of oncologic and non-oncologic indications. The most compelling advantage of TFR is the achievement of immediate fixation which permits early mobilization. It is anticipated that TFR will be increasingly performed as the rate of revision arthroplasty rises worldwide. The existing literature is mainly composed of a rather heterogeneous mix of retrospective case series and a wide assortment of case reports. Numerous TFR prostheses are currently available and the surgeon must understand the unique implications of each implant design. Long-term functional outcomes are dependent on adherence to proper technique and an appropriate physical therapy program for postoperative rehabilitation. Revision TFR is mainly performed for periprosthetic infection and the severe femoral bone loss associated with aseptic revisions. Depending on the likelihood of attaining infection clearance, it may sometimes be advisable to proceed directly to hip disarticulation without attempting salvage of the TFR. Other reported complications of TFR include hip joint instability, limb length discrepancy, device failure, component loosening, patellar maltracking and delayed wound healing. Further research is needed to better characterize the long-term functional outcomes and complications associated with this complex procedure. | Deepak Ramanathan Marcelo BP Siqueira Alison K Klika Carlos A Higuera Wael K Barsoum Michael J Joyce | 2015 | World Journal of Orthopedics2015，6，11： | 6 |
| 3 | Growth of carbon- doped GaAs, AlGaAs and InGaAs by chemical beam epitaxy and the application of in- situ monitoring显示文摘 | Joyce T B Westwater S P Goodhew P J | 1996 | J Crystal Growth1996，164，： | 2 |
| 4 | Clinical use of genotype to predict chemosensitivity in oligodendroglial tumors显示文摘 | Walker C Haylock B Husband D Joyce KA Fildes D Jenkirtson MD Smith T Broome J du Plessis DG Warnke PC | 2006 | 中国神经肿瘤杂志2006，4，3： | 2 |
| 5 | Insulinoma: pathophysiology, localization and management显示文摘 | Joyce J Shin Phillip Gorden Steven K Libutti | 2010 | Future Oncol2010，，2： | 2 |
| 6 | ATP-induced changes in energy status and membrane integrity of harvested litchi fruit and its relation to pathogen resistance 显示文摘 | YI C QU H X JIANG Y M SHI J DUAN X W JOYCE D C LI Y B | 2008 | Journal of Phytopathology2008，156，： | 1 |
| 7 | The prognosis of chronic fatigue and chronic fatigue syndrome: a systematic review显示文摘 | Hotopf M Wessely S | 1997 | QJM1997，90，3： | 1 |
| 8 | Dorsiflexor and plantar flexor muscle fatigue decreases postural control显示文摘 | JOYCE C J PERRIN D H ARNOLD B L | 2001 | J Athl Train2001，36，： | 1 |
| 9 | The ATP bindingcassette transporterA1 ( ABCA1 ) modulates the developmentof aortic atherosclerosis in C57BL/6 and apoE-knockoutmice 显示文摘 | JOYCE C W AMARM J LAMBERT G | 2002 | Proc Natl Acad Sci U S A2002，99，1： | 1 |
| 10 | Role of two- and three-dimensional sueface structures in InAs GaAs(001) quantum dot nucleation显示文摘 | KRZYZEWSKI T J JOYCE P B BELL G R | 2002 | Phys Rev B2002，66，12： | 1 |
| 11 | The L1 majore capsid protein of human papillomavirus type 11 recombinant virus-like particles interacts with heparin and cell-surphace glycosaminoglycans on human keratinocytes显示文摘 | JOYCE J G TUNG J S PRZYSIECKI C T | 1999 | J Biol Chem1999，274，： | 1 |
| 12 | Erythropoietin acts as atrophic factor in neonatal rat intestine 显示文摘 | Juul S E Ledbetter D J Joyce A E | 2001 | Gut2001，49，2： | 1 |
| 13 | Multiple roles for cysteine cathepsins in cancer显示文摘 | JOYCE J A HANAHAN D | 2004 | Cell Cycle2004，3，12： | 1 |
| 14 | Epithelium- deficient corneal allografts display immune privilege beneath the kidney capsule显示文摘 | Hori J Joyce N Streilein JW | 2000 | Invest Ophthalmol Vis Sci2000，41，3： | 1 |
| 15 | Determination of the enantiomers of salbutamol and its 4-Osulphate metabolites in biological matrices by chiral liquid chromatography tandem mass spectrometry 显示文摘 | Joyce K B Jones A E Scott R J | 1998 | Rapid Commum Mass Spectrom1998，12，： | 1 |
| 16 | Sucrose utilization during potato microtuber growth in bioreactors显示文摘 | Yu W C Joyce P J Cameron D C | 2000 | Plant Cell Reports2000，19，： | 1 |
| 17 | Response of banana fruit to treatment with 1-methylcyclopropene显示文摘 | Jiang Y M Joyce D C Macnish A J | 1999 | Plant Grow Regul1999，28，： | 1 |
| 18 | Microenvironmental regulation of metasta- sis显示文摘 | Joyce J A Pollard J W | 2009 | Nat Rev Cancer2009，9，4： | 1 |
| 19 | III-V semiconductor nanowires for optoelectronic device applications 显示文摘 | Joyce Hannah J | 2011 | Progress in Quan- tum Electronics2011，35，23： | 1 |
| 20 | Models of transitional care for young people with complex health needs:A sco ping review显示文摘 | Watson R Parr J R Joyce C | 2011 | Child Care Health2011，37，6： | 1 |
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