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| 1 | Bt水稻对飞虱和叶蝉及其卵寄生蜂扩散规律的影响显示文摘研究了Bt水稻两个纯合品系TT9-3和TT9-4在田间对飞虱、叶蝉及其卵寄生蜂扩散规律的影响。结果表明:在Bt稻区与对照(IR72)区间相互扩散的飞虱有白背飞虱(Sogatellafurcifea)、褐飞虱(Nilaparvatalugens);叶蝉有黑尾叶蝉(Nephotetixcincticeps)、白翅叶蝉(Erythroneurasubrufa)和电光叶蝉(Deltpcephalusdorsalis);其中以白背飞虱和黑尾叶蝉为主。扩散数量叶蝉多于飞虱;扩散方向以Bt稻区向对照区扩散为主,其中TT9-3与IR72、TT9-4与IR72间白背飞虱与黑尾叶蝉的扩散量差异均达显著水平(P<0.05)。在Bt稻区与对照区间相互扩散的飞虱和叶蝉的卵寄生蜂有稻虱缨小蜂(Anagrusspp.)和叶蝉柄翅小蜂(Lynaenonlongicrus),数量上后者多于前者,扩散方向也以Bt稻区向对照区扩散为主。 | 陈茂 叶恭银 胡萃 Tu J Datta S K | 2003 | 浙江大学学报(农业与生命科学版)2003，29，1： | 30 |
| 2 | 以基因枪介导获转ps1-barnase基因的工程雄性不育水稻植株显示文摘以ps1-barnase(brn)为目的基因,pHcintG(PG)为选择/标记基因进行共转化,以PDS-1000-氦气基因枪介导,将brn及PG基因转化到水稻台北309及秋光的核DNA中,得到了转ps1-barnase基因的工程雄性不育植株。以悬浮细胞作为基因枪轰击的靶材料,转化植株再生频率较初级愈伤组织的为高。转brn基因植株的其他主要性状与供体亲本无显著差异,但却表现不育。其不育的程度在不同的植株之间表现不同。在转brn基因植株中观察到全不育(占全部brn阳性植株的40.6%)、高不育(占15.6%)及半不育的个体(占43.7%)。全不育的转基因植株自交完全不能结实(结实率为零),除个别植株外,花粉完全不被I-KI染色;而人工授以正常的花粉则可以获得杂交种子。而brn基因的阴性植株及未进行转化的对照植株则完全可育,表明转基因植株之雄性不育乃brn基因所致。结果表明,brn基因在水稻中是完全可以正常表达的,其表达的时期推测在花粉母细胞减数分裂前至花粉形成之间的整个时期。 | 凌定厚 陶利珍 马镇荣 S P Zhang S K Datta | 1998 | Acta Genetica Sinica1998，25，5： | 23 |
| 3 | Hepatitis viruses and non-Hodgkin's lymphoma: A review显示文摘Non-Hodgkin's lymphoma(NHL) is among the haematological malignancies with high prevalence worldwide, causing estimated 355 900 new cases and 191 400 deaths in 2008. High prevalence of NHL is documented in economically more developed areas while low prevalence is observed in less developed areas of the globe. A wide array of environmental factors have been reported to be either directly involved or in modifying the risk of NHL development. In addition to these factors, a number of infectious agents, chiefly viruses have also been implicated in the development of NHL. This article reviews the available literature to discuss the role of hepatitis viruses in NHL development, possible mechanisms of lymphomagenesis and also identify the areas in which further research is required to better understand this disease. A brief discussion on the clinical aspects such as classification, staging, treatment approaches have also been included in this article. | Sibnarayan Datta Soumya Chatterjee Rudragoud S Policegoudra Hemant K Gogoi Lokendra Singh | 2012 | World Journal of Virology2012，1，6： | 11 |
| 4 | Non-alcoholic fatty liver disease may not be a severe disease at presentation among Asian Indians显示文摘瞄准:与非含酒精的脂肝疾病(NAFLD ) 评估病人的临床、生物化学的侧面并且在表示估计他们的组织学的严厉。方法:介绍给所有印度的肝诊所的连续病人与提起的 transaminases 医学科学(AIIMS ) 开创到乘正常的上面的限制的至少 1.5,并且组织学地证实的非酒精的脂肝疾病被包括。或谁有重要白酒吸入或另外的肝疾病的积极标记的病人正在服知道生产脂肝的药被排除。这个组的临床、生物化学、组织学的侧面被学习。结果:有 NAFLD 的 51 个病人形成了学习人口。他们的中部的年龄和 BMI 是 34 (17-58 ) 年并且 26.7 (21.3-32.5 ) kg/m (2 ) 分别地并且(90.1%) 46 是男性。病人的多数有温和发炎,也分级 1 [32 (63%)] 或等级 2 [16 (31%)] 并且仅仅 3 (6%) 病人们有严重(等级 3 ) 发炎。23 (45%) , 19 (37%) , 8 (16%) 并且 1 (2%) 病人有 0, 1, 2 和 3 纤维变性分别地在索引活体检视和没有上有的舞台肝硬化。在 univariate 分析上,甘油三酸酯铺平超过 150 mg %( 或 = 7.1;95% CI:1.6-31.5, P = 0.002 ) 并且著名计算机生产厂商 / 中高音 ratio>1 (或 = 14.3;95% CI:1.4-678.5, P = 0.008 ) 与发炎的高等级被联系,任何一个都没与先进纤维变性被联系。在上多变量逻辑回归分析, hypertriglyceridemia >150 mg% 是独立地与发炎的高等级的存在联系的唯一的因素(或 = 1.6;95% CI:1.3-22.7, P = 0.02 ) ,当任何一个都没与先进纤维变性被联系时。甘油三酸酯层次与煽动性的等级断然相关(r = 0.412;P = 0.003 ) 。结论:在诺思印第安人病人的 NAFLD 是年轻超重男性,其中大多数是抵抗的胰岛素的疾病,他们趋于在表示有温和组织学的疾病。 | Kaushal Madan Yogesh Batra S Datta Gupta Bal Chander K D Anand Rajan M S Tewatia S K Panda S K Acharya | 2006 | World Journal of Gastroenterology2006，12，21： | 7 |
| 5 | Distribution of hepatitis B virus genotypes:Phylogenetic analysis and virological characteristics of Genotype C circulating among HBV carriers in Kolkata,Eastern India显示文摘AIM: To evaluate the genotype distribution of hepatitis B virus (HBV) in Eastern India and to clarify the phyloge- netic origin and virological characteristics of the recently identifi ed genotype C in this region. METHODS: Genotype determination, T1762/A1764 mutation in the basal core promoter (BCP) and A1896 mutation in the precore region of 230 subjects were de- termined by restriction fragment length polymorphism method (RFLP) and the result was confi rmed by direct sequencing. RESULTS: The predominant genotypes D (HBV/D) and A (HBV/A) were detected in 131/230 (57%) and 57/230 (25%) samples. In addition, genotype C (HBV/C) was detected in 42/230 (18%) isolates. Surface gene region was sequenced from 45 isolates (27 HBV/C, 9 HBV/A and 9 HBV/D). Phylogenetic analysis revealed that all of the HBV/C sequences clustered with South East Asian subgenotype (HBV/Cs). The sequence data showed re- markable similarity with a Thai strain (AF068756) (99.5% ± 0.4% nucleotide identities) in 90% of the genotype C strains analyzed. T1762/A1764 mutation in BCP re- gion, associated with high ALT was signifi cantly higher in HBeAg negative isolates than HBeAg positive isolates. Frequency of A1896 mutation leading to HBeAg negativ- ity was low.CONCLUSION: The present study reports the genotypic distribution and the characteristics of partial genome sequences of HBV/C isolates from Eastern India. Low genetic diversity and confi nement of HBV/C in Eastern India possibly indicate a recent, limited, spread in this region. Genotype C with T1762/A1764 mutation has been reported to increase the risk for hepatocellular car- cinoma; therefore genotype C carriers in Eastern India should be carefully monitored. | Arup Banerjee Sibnarayan Datta Partha K Chandra Susanta Roychowdhury Chinmoy Kumar Panda Runu Chakravarty | 2006 | World Journal of Gastroenterology2006，12，37： | 3 |
| 6 | Acanthus ilicifolius plant extract prevents DNA alterations in a transplantable Ehrlich ascites carcinoma-bearing murine model显示文摘AIM: To investigate the chemopreventive efficacy of the Indian medicinal plant Acanthus ilicifolius L Acanthaceae in a transplantable Ehrlich ascites carcinoma (EAC)- bearing murine model. METHODS: Male Swiss albino mice were divided into four groups: Group A was the untreated normal control; Group B was the EAC control mice group that received serial, intraperitoneal (ip) inoculations of rapidly proliferating 2 x 105 viable EAC cells in 0.2 mL of sterile phosphate buffered saline; Group C was the plant extract-treated group that received the aqueous leaf extract (ALE) of the plant at a dose of 2.5 mg/kg body weight by single ip injections, once daily for 10, 20 and 30 consecutive days following tumour inoculation (ALE control); and Group D was the EAC + ALE- treatment group. The chemopreventive potential of the ALE was evaluated in a murine model by studying various biological parameters and genotoxic markers, such as tumour cell count, mean survival of the animals, haematological indices, hepatocellular histology, immunohistochemical expression of liver metallothionein (MT) protein, sister-chromatid exchanges (SCEs), and DNA alterations.RESULTS: Treatment of the EAC-bearing mice with the ALE significantly (P < 0.001) reduced viable tumour cell count by 68.34% (228.7 x 106 ± 0.53) when compared to EAC control mice (72.4 x 106 ± 0.49), and restored body and organ weights almost to the normal values. ALE administration also increased (P < 0.001) mean survival of the hosts from 35 ± 3.46 d in EAC control mice to 83 ± 2.69 d in EAC + ALE-treated mice. Haematological indices also showed marked improvement with administration of ALE in EAC-bearing animals. There was a significant increase in RBC count (P < 0.001), hemoglobin percent (P < 0.001), and haematocrit value (P < 0.001) from 4.3 ± 0.12, 6.4 ± 0.93, and 17.63 ± 0.72 respectively in EAC control mice to 7.1 ± 0.13, 12.1 ± 0.77, and 30.23 ± 0.57 respectively in EAC + ALE-treated group, along with concurrent decrement (P < 0.001) in WBC count from 18.8 ± 0.54 in EAC control to 8.4 ± 0.71 in EAC + ALE. Furthermore, treatment with ALE substantially improved hepatocellular architecture and no noticeable neoplastic lesions or foci of cellular alteration were observed. Daily administration of the ALE was found to limit liver MT expression, an important marker of cell proliferation with concomitant reduction in MT immunoreactivity (62.25 ± 2.58 vs 86.24 ± 5.69, P < 0.01). ALE was also potentially effective in reducing (P < 0.001) the frequency of SCEs from 14.94 ± 2.14 in EAC control to 5.12 ± 1.16 in EAC + ALE-treated group. Finally, in comparison to the EAC control, ALE was able to suppress in vivo DNA damage by abating the generations of ‘tailed’ DNA by 53.59% (98.65 ± 2.31 vs 45.06 ± 1.14, P < 0.001), and DNA single-strand breaks (SSBs) by 38.53% (3.14 ± 0.31 vs 1.93 ± 0.23, P < 0.01) in EAC-bearing murine liver. CONCLUSION: Our data indicate that, ALE is beneficial in restoring haematological and hepatic histological profiles and in lengthening the survival of the animals against the proliferation of ascites tumour in vivo. Finally, the chemopreventive efficacy of the ALE is manifested in limiting MT expression and in preventing DNA alterations in murine liver. The promising results of this study suggest further investigation into the chemopreventive mechanisms of the medicinal plant A. ilicifolius in vivo and in vitro. | Tridib Chakraborty Dipak Bhuniya Mary Chatterjee Mosiur Rahaman Dipak Singha Baidya Nath Chatterjee Subrata Datta Ajay Rana Kartick Samanta Sunil Srivastawa Sankar K Maitra Malay Chatterjee | 2007 | World Journal of Gastroenterology2007，13，48： | 2 |
| 7 | The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase显示文摘 | Thomas F Franke Sung-Il Yang Tung O Chan Ketaki Datta Andrius Kazlauskas Deborah K Morrison David R Kaplan Philip N Tsichlis | 1995 | Cell1995，，5： | 2 |
| 8 | Elastic wave propagation in laminated composite plates 显示文摘 | Karunasena W M Bratton R L Datta S K | 1990 | ASME J Eng Mat Tech1990，113，： | 2 |
| 9 | Wave propagation in a mulitilayered laminated cross-ply composite plate 显示文摘 | Karunasena W Shah A H Datta S K | 1991 | ASME J Appl Mec1991，58，： | 2 |
| 10 | Targeting the transforming growth factor-β signaling pathway in human cancer显示文摘 | Nagathihalli S Nagaraj Pran K Datta | 2010 | Expert Opinion on Investigational Drugs2010，，： | 2 |
| 11 | Central role of p53 on regulation of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) expression in mammay carcinoma显示文摘 | Datta K Mukhopadhyay D | 2001 | Cancer Res2001，61，18： | 1 |
| 12 | The 104 125 amino acid sequence of the beta-domain of yon HippeI--Lindau gene product is sufficient to inhibit renal tumor growth and fnvasion显示文摘 | Datta K Sundberg C Karumanchis A | 2001 | Oancer Res2001，61，5： | 1 |
| 13 | Measurement of nitro- gen utilization efficiency in rice genotypes 显示文摘 | BROADBENT F E DATTA S K LAURELES E V | 1987 | Agron J1987，79，： | 1 |
| 14 | Evolution and soil entrapment of nitrogen gases formed by denitrification in flooded soil 显示文摘 | Samson M I Buresh R J De Datta S K | 1990 | Soil Science and Plant Nutrition1990，36，： | 1 |
| 15 | Optimal use of viscoelastic dampers in building frames for seismic response显示文摘 | Shulla A K Datta T K | 1999 | J of Structural Engineering1999，125，4： | 1 |
| 16 | Dynamic stress and displacement around cylindrical cavities of arbitrary shapes显示文摘 | Datta S K Wong K C Shah A H | 1984 | ASME Journal of Applied Mechanics1984，51，： | 1 |
| 17 | Texture and mineralogy of sediments from the Ganges-Brahmaputra-Meghna river system in the Bengal Basin, Bangladesh and their environmental implications 显示文摘 | Datta D K Subramanian V | 1997 | Environ Geol1997，30，34： | 1 |
| 18 | Bougainvillea research at National Botanical Research Institute, Lucknow显示文摘 | Datta S K | 2004 | J Omam Hort2004，7，1： | 1 |
| 19 | Generation of hydrogen rich gas through fluidized bed gasification of biomass显示文摘 | Karmakar M K Datta A B | 2011 | Bioresource Technology2011，102，2： | 1 |
| 20 | Seismic risk analysis of modified fan type cable stayed bridges 显示文摘 | Khan R A Datta T K Ahrnad S | 2006 | Engineering Structures2006，28，9： | 1 |
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