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| 1 | Epigenetics and chromatin plasticity in embryonic stem cells显示文摘The study of embryonic stem cells is in the spotlight in many laboratories that study the structure and function of chromatin and epigenetic processes. The key properties of embryonic stem cells are their capacity for selfrenewal and their pluripotency. Pluripotent stem cells are able to differentiate into the cells of all three germ layers, and because of this property they represent a promising therapeutic tool in the treatment of diseases such as Parkinson's disease and diabetes, or in the healing of lesions after heart attack. As the basic nuclear unit, chromatin is responsible for the regulation of the functional status of cells, including pluripotency and differentiation. Therefore, in this review we discuss the functional changes in chromatin during differentiation and the correlation between epigenetics events and the differentiation potential of embryonic stem cells. In particular we focus on post-translational histone modification, DNA methylation and the heterochromatin protein HP1 and its unique function in mouse and human embryonic stem cells. | Terézia Pikrylová Jií Pacherník Stanislav Kozubek Eva Bártová | 2013 | World Journal of Stem Cells2013，5，3： | 3 |
| 2 | Deformation behaviour of Mg–Li–Al alloys显示文摘 | Zdeněk Drozd Zuzanka Trojanová Stanislav Kúdela | 2004 | Journal of Alloys and Compounds2004，，1： | 2 |
| 3 | A solution for self-calibrating alarge distorted phased array using subarray processing显示文摘 | BONGSOON K BERNARD D S STANISLAV B K | 1991 | IEEE Transactions on Antennas and Propagation1991，39，3： | 1 |
| 4 | Deformation behav- ior of Mg-Li-AI alloys显示文摘 | ZDENEK D LUZANKA T STANISLAV K | 2004 | Journal of Alloys and Compounds2004，378，： | 1 |
| 5 | A two-stage dynamic model for visual tracking显示文摘 | Matej K Stanislav K | 2010 | IEEE Transactions on SMC Part B2010，40，6： | 1 |
| 6 | Preoperative tumor markers as prognostic factors of colorectal liver metastases显示文摘 | Treska V Topolcan O Stanislav K | | 0，，90： | 1 |
| 7 | Preoperative tumor markers as prognostic factors of colorectal liver metastases显示文摘 | Treska V Topolcan O Stanislav K | 2009 | Hepatogastroenterology2009，56，90： | 1 |
| 8 | Fate of deoxynivalenol and nivalenol during storage of organic whole-grain wheat flour显示文摘 | ALES K ANDREJ S STANISLAV V | 2010 | Journal of Stored Products Research2010，46，1： | 1 |
| 9 | Objective evaluation of the effect of autologous platelet concentrate on post-operative scarring in deep burns显示文摘 | Hana Klosová Ji?í ?tětinsky Iveta Bryjová Stanislav Hledík Leo Klein | 2013 | Burns2013，，6： | 1 |
| 10 | Human adenylosuccinate lyase (ADSL), cloning and characterization of full-length eDNA and its isoform, gene structure and molecular basis for ADSL deficiency in six patients显示文摘 | STANISLAV K HANA H BLANKA S | 2000 | Human Molecular Genetics2000，10，： | 1 |
| 11 | Influence of mineral and chemical composition of coal ashes on their fusibility显示文摘 | Stanislav V Vassilev K Shohei T | 1995 | Fuel Processing Technology1995，45，1： | 1 |
| 12 | Investigation of crack propagation scatter in a gear tooth's root显示文摘 | Stanislav P Janez K Jo(z)e F | 2008 | Engineering Fracture Mechanics2008，75，5： | 1 |
| 13 | Derivation of equivalent materialmodels for composite laminated materials 显示文摘 | Stanislav G Vojtech K | 2009 | RadioEngineering *2009，18，： | 1 |
| 14 | Sig- nal- to- noise ratio enhancement based on? wavelet filtering in ultrasonic testing显示文摘 | Vaelav M Radislav S Stanislav Smarcel K | 2009 | Ultrasonics2009，49，8： | 1 |
| 15 | Biosorption of Cd2 and Zn2+ by Cell Surface-engineered Saecharomyces Cerevisiae显示文摘 | Stanislav V Tomas R K | 2006 | International Biodeterioration & Biodegradation2006，60，2： | 1 |
| 16 | Synthesis and in vitro antiprotozoal activities of dicationic 3,5-diphenylisoxazoles显示文摘 | Stanislav A Bakunov Svetlana M Bakunova E V K Suresh Kumar et al | 2007 | J Med Chem2007，50，： | 1 |
| 17 | Deformation behavior of Mg-Li-Al alloys显示文摘 | ZDENVEK D ZUZANKA T STANISLAV K | 2004 | Journal of Alloys and Compounds2004，378，： | 1 |
| 18 | Penicillin G acylase from Achromobacter sp. CCM 4824显示文摘 | Stanislav Be?ka Václav ?těpánek Rajasekar W. Vyasarayani Michal Grulich Jaroslav Mar?álek Kamila Plhá?ková Marie Dobi?ová Helena Mare?ová Martina Pla?ková Renáta Vale?ová Andrea Palyzová Anupama Datla Trupti K. Ashar Pavel Kyslík | 2014 | Applied Microbiology and Biotechnology2014，，3： | 1 |
| 19 | Deficiency of Adenomatous Polyposis Coli protein in sporadic colorectal adenomas and its associations with clinical phenotype and histology显示文摘瞄准:评估腺瘤结肠息肉病(APC ) 蛋白质的损失的频率并且把 APC 地位与颜色的特征作比较表面的腺瘤。方法:APC 蛋白质的 Immunohistochemical 分析在 118 个腺瘤上被执行,结果与病人的恶意的潜力,腺瘤的地点,宏观的外观和年龄的参数相比。结果:APC 蛋白质的完全的损失在 28 被发现的 A (24%) 腺瘤,当(76%) 90 是 APC 时积极。腺瘤的吝啬的尺寸是 13.5 +/- 14.2 公里(95% CI 10.5-16.5 ) 在 APC 积极,并且 13.8 +/- 在 APC 否定的腺瘤的 15.5 公里(95% CI 7.8-19.8 )(P = 0.364 ) 。统计分析没至于组织学的类型揭示 APC 积极、否定的腺瘤之间的差别(P = 0.327 ) 并且发育异常的等级(P = 0.494 ) 。我们发现甚至先进的腺瘤没与非先进的肿瘤在他们的 APC 地位不同(P = 0.414 ) 。最后,当时,没有差别被发现地点(P = 0.157 ) ,宏观的外观(P = 0.571 ) 并且病人的年龄(P = 0.438 ) 在两个 APC 积极、否定的腺瘤之间被分析并且比较。结论:大多数腺瘤表示了全身的 APC 蛋白质,建议那蛋白质表情不是为对 APC 基因变化的评价的一个可靠标记。APC 蛋白质的完全的损失没影响腺瘤的形态学,地点,或外观,它也不受病人的年龄影响。 | Martin Bortlík Ivana Vítková Martina Pape(z|ˇ)ová Milada Kohoutová Ale(s|ˇ) Novotn(y|') Stanislav Adamec Petra Chalupná Milan Luká(s|ˇ) | 2006 | World Journal of Gastroenterology2006，12，24： | 1 |
| 20 | An overview of the ehemical compositon of biomass 显示文摘 | Stanislav V Vassilev David Baxter Lars K Andersen | 2010 | Fuel2010，89，5： | 1 |
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