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| 1 | Serum positive cagA in patients with non-ulcer dyspepsia and peptic ulcer disease from two centers in different regions of Turkey显示文摘AIM: To investigate and compare frequencies of serum positive cagA in patients from two separate regions of Turkey who were grouped according to the presence of peptic ulcer disease or non-ulcer dyspepsia.METHODS: One hundred and eighty Helicobacter pyloripositive patients with peptic ulcer disease or non-ulcer dyspepsia were included in the study. One hundred and fourteen patients had non-ulcer dyspepsia and 66 had peptic ulcer disease (32 with gastric ulcers and/or erosions and 34with duodenal ulcers). Each patient was tested for serum antibody to H. pylori cagA protein by enzyme immunoassay.RESULTS: The total frequency of serum positive cagA in the study group was 97.2 %. The rates in the patients with peptic ulcers and in those with non-ulcer dyspepsia were 100% and 95.6%, respectively. These results were similar to those reported in Asian studies, but higher than those that have been noted in other studies from Turkey and Western countries.CONCLUSION: The high rates of serum positive cagA in these patients with peptic ulcer disease and non-ulcer dyspepsia were similar to results reported in Asia. The fact that there was high seroum prevalence regardless of ulcer status suggests that factors other than cagA might be responsible for ulceration or other types of severe pathology in H. pylori-positive individuals. | Ender Serin Uur Yilmaz Ganiye Künefeci Birol zer Yüksel Gümürdülü Mustafa Gülü Fazilet Kayaseluk Sedat Boyaciolu | 2003 | World Journal of Gastroenterology2003，9，4： | 10 |
| 2 | Mesenchymal stem cell therapy in patients with small bowel transplantation:Single center experience显示文摘AIM:To study the effects of mesenchymal stem cell(MSC) therapy on the prevention of acute rejection and graft vs host disease following small bowel transplantation.METHODS: In our transplantation center, 6 isolated intestinal transplants have been performed with MSC therapy since 2009. The primary reasons for transplants were short gut syndrome caused by surgical intestine resection for superior mesenteric artery thrombosis(n = 4), Crohn's disease(n = 1) and intestinal aganglionosis(n = 1). Two of the patients were children. At the time of reperfusion, the first dose of MSCs cultured from the patient's bone marrow was passedinto the transplanted intestinal artery at a dose of 1000000 cells/kg. The second and third doses of MSCs were given directly into the mesenteric artery through the arterial anastomosis using an angiography catheter on day 15 and 30 post-transplant.RESULTS: The median follow-up for these patients was 10.6 mo(min: 2 mo-max: 30 mo). Three of the patients developed severe acute rejection. One of these patients did not respond to bolus steroid therapy. Although the other two patients did respond to antirejection treatment, they developed severe fungal and bacterial infections. All of these patients died in the 2nd and 3rd months post-transplant due to sepsis. The remaining patients who did not have acute rejection had good quality of life with no complications observed during the follow-up period. In addition, their intestinal grafts were functioning properly in the 13th, 25th and 30th month post-transplant. The patients who survived did not encounter any problems related to MSC transplantation.CONCLUSION: Although this is a small case series and not a randomized study, it is our opinion that small bowel transplantation is an effective treatment for intestinal failure, and MSC therapy may help to prevent acute rejection and graft vs host disease following intestinal transplantation. | Sait Murat Do?an Sel?uk K?l?n? Eyüp Kebap?? Cem Tu?men Mustafa ?lmez Cezmi Karaca Alp Gürkan Ma?allah Baran Yusuf Kurtulmu? | 2014 | World Journal of Gastroenterology2014，20，25： | 3 |
| 3 | The predictive value of triglyceride-glucose index for in-hospital and one-year mortality in elderly non-diabetic patients with ST-segment elevation myocardial infarction显示文摘BACKGROUND Triglyceride-glucose(TyG)index,a reliable marker of insulin resistance,was associated with cardiovascular morbidity and mortality.This study aimed to evaluate the predictive value of TyG index for mortality in elderly non-diabetic pa-tients with ST-segment elevation myocardial infarction(STEMI).METHODS In total,430 non-diabetic patients aged over 65 years with STEMI were consecutively included.The TyG index was calculated by using the following formula:TyG index=ln(fasting triglyceride×fasting glucose/2).The 5-item modified frailty index score was utilized to determine comorbidities.Patients were divided into three groups based on TyG index tertiles.RESULTS Patients included into high TyG index tertile were male and had higher body mass index,glucose,triglyceride,low-density lipoprotein cholesterol,5-item modified frailty index and GRACE risk score;and had low systolic blood pressure,estim-ated glomerular filtration rate and left ventricular ejection fraction.A one-unit increase in TyG index was associated with 3.03 ex-tra cases per 1000 person-day for in-hospital mortality and 0.29 extra cases per 1000 person-day for long-term mortality.There was a non-linear relationship between TyG index and the risk of mortality with an increased risk above 8.5 for TyG index.Kaplan-Meier survival curves revealed that patients in high TyG index tertile had higher in-hospital and long-term mortality rates than those in low TyG index tertile.CONCLUSIONS This was the first study to demonstrate that the TyG index could predict in-hospital and long-term mortality in elderly non-diabetic STEMI patients. | FaysalŞaylık TufanÇınar Murat Selçuk İbrahim Halil Tanboğa | 2022 | Journal of Geriatric Cardiology2022，19，8： | 3 |
| 4 | Perineural pretreatment of bee venom attenuated the development of allodynia in the spinal nerve ligation injured neuropathic pain model;an experimental study显示文摘 | Uk K W Soo C S Hyuk L J | 2014 | BMC complementary and alternative medicine2014，14，1： | 1 |
| 5 | Pathophysiology of cataract formation after vitrectomy显示文摘 | Petermeier K Szurman P Bartz Schmidt UK | 2010 | Klin Monbl Augen- heilkd2010，227，3： | 1 |
| 6 | Borrelia burgdorferi activates nuclear factor-κB and is a potent inducer of chemokine and adhesion molecule gene expression in endothelial cells and fibroblasts显示文摘 | Ebnet K Brown KD Siebenlist UK | 1997 | J Immunol1997，158，7： | 1 |
| 7 | Penetration of 6061 - T6651 aluminium targets with rigid long rods显示文摘 | Forrestal MT Okajima K L uk V K | 1988 | Journal of Applied Mechanics1988，55，4： | 1 |
| 8 | Investigation of copper deposition in the presence of benzotriazole 显示文摘 | Kim J J K S K Bae J UK | 2002 | The Solid Films2002，，415： | 1 |
| 9 | Pseudomonas Aeruginosa Exotoxin A Reduces Chemoresistance of Oral Squamous Carcinoma Cell via Inhibition of Heat Shock Proteins 70 (HSP70)显示文摘 | SANG R P KYOUNG D L UK K K | 2010 | Yonsei Med J2010，51，5： | 1 |
| 10 | Lowdose nonenhanced head CT protocol for follow-up evaluation of children with ventriculoperitoneal shunt: reduction of radiation and effect on intage quality 显示文摘 | Udayasankar UK Braithwaite K Arvaniti M et aI | 2008 | AJNR2008，29，： | 1 |
| 11 | Reasoning for Web Document Associations and Its Applications in Site Map Construction显示文摘 | Sel?uk K Li Wen-Syan | 2002 | Data & Knowledge Engineering2002，43，2： | 1 |
| 12 | MDCT diagnosis of penetrating diaphragm injury显示文摘 | Bodanapally UK Shanmuganathan K Mirvis SE | 2009 | Eur Radiol2009，19，8： | 1 |
| 13 | The association between elevated EphB4 expression, smoking status, and advanced stage disease in pa- tients with head and neck squamous cell carcinoma显示文摘 | Sinha UK Mazhar K Chinn SB | 2006 | Arch Otolaryn- gol Head Neck Surg2006，132，10： | 1 |
| 14 | Replacement of in vivo acute oral toxicity studies by in vitro cytotoxicity methods: opportunities, limits and regulatory status 显示文摘 | Ukelis U Kramer PJ Olejniczak K | 2008 | Regul Toxicol Pharm2008，51，1： | 1 |
| 15 | Engineering of xylose reduetase and overexpres- sion of xylitol dehydrogenase and xylulokinase improves xylose alcoholic fermentation in the thermotolerant yeast Hansenula polymorpha显示文摘 | Dmytruk 0 V Dmyt'uk K V Abbas C A Voronovsky A Y Sibirny A A | 2008 | Mierob Cell Fact2008，7，： | 1 |
| 16 | Low-dosenonenhanced head CT protocol for follow- up evaluationof childrenwith ventriculoperitoneal shuntireductionof radiation and effect on image quality显示文摘 | Udayasankar UK Braithwaite K Arvaniti M | 2008 | AJNR Am JNeuroradiol2008，29，4： | 1 |
| 17 | Determination of full moment tensors of microseismic events in a very heterogeneous mining environment显示文摘 | KHN D VAVRYUK V | 2013 | Tectonophysics2013，589，： | 1 |
| 18 | Immunohistochemical detection of p53 and p63 in oral squamous cell carcinoma, oral leukoplakia, and oral submucous fibrosis显示文摘 | Varun BR Ranganathan K Rao UK | 2014 | Journal of Investiga- tive and Clinical Dentistry2014，5，3： | 1 |
| 19 | Use of AlloDerm for coverage of radial forearm free flap donor site显示文摘 | Shih C Chang K | 2002 | Laryngolcope2002，112，2： | 1 |
| 20 | Vitamin D Intake in Very Low Birth Weight Infants in Neonatal Intensive Care Unit 显示文摘 | Munshi UK Graziano PD Meunier K | 2016 | J Pediatr Gastroenterol Nutr2016，63，2： | 1 |
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