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| 1 | Lessons learned from an audit of 1250 anal fistula patients operated at a single center:A retrospective review显示文摘BACKGROUND A complex anal fistula is a challenging disease to manage.AIM To review the experience and insights gained in treating a large cohort of patients at an exclusive fistula center.METHODS Anal fistulas operated on by a single surgeon over 14 years were analyzed.Preoperative magnetic resonance imaging was done in all patients.Four procedures were performed:fistulotomy;two novel sphincter-saving procedures,proximal superficial cauterization of the internal opening and regular emptying and curettage of fistula tracts(PERFACT)and transanal opening of intersphincteric space(TROPIS),and anal fistula plug.PERFACT was initiated before TROPIS.As per the institutional GFRI algorithm,fistulotomy was done in simple fistulas,and TROPIS was done in complex fistulas.Fistulas with associated abscesses were treated by definitive surgery.Incontinence was evaluated objectively by Vaizey incontinence scores.RESULTS A total of 1351 anal fistula operations were performed in 1250 patients.The overall fistula healing rate was 19.4%in anal fistula plug(n=56),50.3%in PERFACT(n=175),86%in TROPIS(n=408),and 98.6%in fistulotomy(n=611)patients.Continence did not change significantly after surgery in any group.As per the new algorithm,1019 patients were operated with either the fistulotomy or TROPIS procedure.The overall success rate was 93.5%in those patients.In a subgroup analysis,the overall healing rate in supralevator,horseshoe,and fistulas with an associated abscess was 82%,85.8%,and 90.6%,respectively.The 90.6%healing rate in fistulas with an associated abscess was comparable to that of fistulas with no abscess(94.5%,P=0.057,not significant).CONCLUSION Fistulotomy had a high 98.6%healing rate in simple fistulas without deterioration of continence if the patient selection was done judiciously.The sphincter-sparing procedure,TROPIS,was safe,with a satisfactory 86%healing rate for complex fistulas.This is the largest anal fistula series to date. | Pankaj Garg Baljit Kaur Ankita Goyal Vipul D Yagnik Sushil Dawka Geetha R Menon | 2021 | World Journal of Gastrointestinal Surgery2021，13，4： | 8 |
| 2 | Guidelines on postoperative magnetic resonance imaging in patients operated for cryptoglandular anal fistula:Experience from 2404 scans显示文摘Magnetic resonance imaging(MRI)is considered the gold standard for the evaluation of anal fistulas.There is sufficient literature available outlining the interpretation of fistula MRI before performing surgery.However,the interpretation of MRI becomes quite challenging in the postoperative period after the surgery of fistula has been undertaken.Incidentally,there are scarce data and no set guidelines regarding analysis of fistula MRI in the postoperative period.In this article,we discuss the challenges faced while interpreting the postoperative MRI,the timing of the postoperative MRI,the utility of MRI in the postoperative period for the management of anal fistulas,the importance of the active involvement and experience of the treating clinician in interpreting MRI scans,and the latest advancements in the field. | Pankaj Garg Baljit Kaur Vipul D Yagnik Sushil Dawka Geetha R Menon | 2021 | World Journal of Gastroenterology2021，27，33： | 6 |
| 3 | Guidelines to diagnose and treat peri-levator high-5 anal fistulas: Supralevator, suprasphincteric, extrasphincteric, high outersphincteric, and high intrarectal fistulas显示文摘Supralevator,suprasphincteric,extrasphincteric,and high intrarectal fistulas(high fistulas in muscle layers of the rectal wall)are well-known high anal fistulas which are considered the most complex and extremely challenging fistulas to manage.Magnetic resonance imaging has brought more clarity to the pathophysiology of these fistulas.Along with these fistulas,a new type of complex fistula in high outersphincteric space,a fistula at the roof of ischiorectal fossa inside the levator ani muscle(RIFIL),has been described.The diagnosis,management,and prognosis of RIFIL fistulas is reported to be even worse than supralevator and suprasphincteric fistulas.There is a lot of confusion regarding the anatomy,diagnosis,and management of these five types of fistulas.The main reason for this is the paucity of literature about these fistulas.The common feature of all these fistulas is their complete involvement of the external anal sphincter.Therefore,fistulotomy,the simplest and most commonly performed procedure,is practically ruled out in these fistulas and a sphincter-saving procedure needs to be performed.Recent advances have provided new insights into the anatomy,radiological modalities,diagnosis,and management of these five types of high fistulas.These have been discussed and guidelines formulated for the diagnosis and treatment of these fistulas for the first time in this paper. | Pankaj Garg Vipul D Yagnik Sushil Dawka Baljit Kaur Geetha R Menon | 2022 | World Journal of Gastroenterology2022，28，16： | 2 |
| 4 | Effects of the Mi 1, N and tabasco genes on infection and reproduction of Meloidogyne mayaguensis on tomato and pepper genotypes 显示文摘 | Brito J A Stanley J D Kaur R | 2007 | Journal of Nematology2007，39，4： | 1 |
| 5 | Geochemistry of Man sar lake sediments, Jammu, India: Implication for source-area weat hering, provenance, and tectonic setting显示文摘 | Brijraj K D A1-Mikhlafi A S Kaur P | 2006 | Journal of Asian Earth Sciences2006，26，： | 1 |
| 6 | Synthesis of 3-oxa-l-dethiacepham and 3-aza-l-dethiacepham analogs 显示文摘 | Sharma S D Kaur V | 1989 | Synthesis1989，，9： | 1 |
| 7 | Novel taxol formulation: polyvinylpyrrolidone nanoparticle-encapsulated taxol for drug delivery in cancer therapy 显示文摘 | Sharma D Chelvi T P Kaur J | 1996 | Oncol Res1996，8，78： | 1 |
| 8 | Agricultural waste material as potential adsorbent for sequestering heavy metal ions from aqueous solutions-a review显示文摘 | SUD D MAHAJAN G KAUR M P | 2008 | Bioresource Technology2008，99，14： | 1 |
| 9 | Complications in Acute Stroke in India(CASTI-I):a multicenter study显示文摘 | Pandian J D Kaur A Jyotsna R | 2011 | J Stroke Cerebrovasc Dis2011，25，5： | 1 |
| 10 | Exome sequencing reveals the likely involvement of SOXIO in uveal melanoma 显示文摘 | Das D Kaur I Ali M J | 2014 | Optom Vis Sci2014，91，7： | 1 |
| 11 | Cerebral Fat Embolism : A diagnostic challenge 显示文摘 | Babita Gupta Manpreet Kaur Nita D' souza | 2011 | Saudi J Anaesth2011，5，3： | 1 |
| 12 | Transformation of tomato using biolistic gun for transient expression of the β-glucuronidase gene显示文摘 | Ruma D Dhaliwal M S Kaur A | 2009 | Indian Journal of Biotechnology2009，8，： | 1 |
| 13 | 查看详情显示文摘 | Sud D Mahajan G Kaur M P | | 0，，14： | 1 |
| 14 | Agricultural waster material as potential adsorbent for sequestering heavy metal ions from aqueous solutions显示文摘 | SUD D MAHAJAN G KAUR M P | | 0，，： | 1 |
| 15 | DNA methylation of hepatitis B virus (HBV) genome associated with the development of hepatocellular carcinoma and occult HBV infection显示文摘 | Kaur P Paliwal A Durantel D | 2010 | J Infect Dis2010，202，5： | 1 |
| 16 | Adsorption studies on the removal of coloring agent phenol red from wastewater using waste materials as adsorbents显示文摘 | MITTAL A kAUR D MALVIYA A | 2009 | Journal of Colloid and Interface Science2009，337，2： | 1 |
| 17 | Influence of Electro- spun Fiber Size On the Separation Efficiency of Thin Film Nanofiltration Composite Membrane显示文摘 | Kaur S Sundarrajan S Rana D | 2012 | Journal of Membrane Science2012，，392： | 1 |
| 18 | Removal of hexavalent chromium from aqueous solution by adsorption on treated sugarcane bagasse using response surface methodological approach显示文摘 | Garg U K Kaur M P Sud D | | 0，，02： | 1 |
| 19 | Cross - linking of sulfonated styrene - ethylene/butylene - styrene triblock polymer via sulfonamide linkages 显示文摘 | Kaur S Florio G Michalak D | 2003 | Polymer2003，43，19： | 1 |
| 20 | Population modeling of the emergence and development of scientific fields 显示文摘 | Bettencourt L Kaiser D Kaur J | 2008 | Sciento - metrics2008，75，3： | 1 |
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