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| 1 | Factor analysis identifies subgroups of constipation显示文摘AIM:To determine whether distinct symptom groupings exist in a constipated population and whether such grouping might correlate with quantifiable pathophysiological measures of colonic dysfunction.METHODS:One hundred and ninety-one patients presenting to a Gastroenterology clinic with constipation and 32 constipated patients responding to a newspaper advertisement completed a 53-item,wide-ranging selfreport questionnaire.One hundred of these patients had colonic transit measured scintigraphically.Factor analysis determined whether constipation-related symptoms grouped into distinct aspects of symptomatology.Cluster analysis was used to determine whether indi-vidual patients naturally group into distinct subtypes.RESULTS:Cluster analysis yielded a 4 cluster solution with the presence or absence of pain and laxative unresponsiveness providing the main descriptors.Amongst all clusters there was a considerable proportion of patients with demonstrable delayed colon transit,irritable bowel syndrome positive criteria and regular stool frequency.The majority of patients with these characteristics also reported regular laxative use.CONCLUSION:Factor analysis identified four constipation subgroups,based on severity and laxative unresponsiveness,in a constipated population.However,clear stratification into clinically identifiable groups remains imprecise. | Philip G Dinning Mike Jones Linda Hunt Sergio E Fuentealba Jamshid Kalanter Denis W King David Z Lubowski Nicholas J Talley Ian J Cook | 2011 | World Journal of Gastroenterology2011，17，11： | 3 |
| 2 | Pulmonary complications after esophagectomy显示文摘 | Christopher E Avendano Patrick A Flume Gerard A Silvestri Lydia B King Carolyn E Reed | 2002 | The Annals of Thoracic Surgery2002，，3： | 2 |
| 3 | Characteristics of near neutral pH stress corrosion cracks in an X65 pipeline显示文摘 | Chen W King F Vokes E | 2002 | Corrosion2002，58，3： | 2 |
| 4 | Stability of fruit quality traits in diverse watermelon cultivars tested in multiple environments显示文摘Lycopene is a naturally occurring red carotenoid compound that is found in watermelon.Lycopene has antioxidant properties.Lycopene content,sugar content and hollowheart resistance are subject to significant genotype×environment interaction(G×E),which makes breeding for these fruit quality traits difficult.The objectives of this study were to(i)evaluate the influence of years and locations on lycopene content,sugar content and hollowheart resistance for a set of watermelon genotypes,and(ii)identify genotypes with high stability for lycopene,sugar,and hollowheart resistance.A diverse set of 40 genotypes was tested over 3 years and 8 locations across the southern United States in replicated,multi-harvest trials.Lycopene was tested in a subset of 10 genotypes.Data were analyzed using univariate and multivariate stability statistics(BLUP-GGE biplot)using SASGxE and RGxE programs.There were strong effects of environment as well as G×E interaction on watermelon quality traits.On the basis of stability measures,genotypes were classified as stable or unstable for each quality trait.'Crimson Sweet'is an inbred line with high quality trait performance as well as trait stability.'Stone Mountain','Tom Watson','Crimson Sweet'and'Minilee'were among the best genotypes for lycopene content,sugar content and hollowheart resistance.We developed a stability chart based on marketable yield and average ranking generated from different stability measures for yield attributes and quality traits.The chart will assist in choosing parents for improvement of watermelon cultivars.See http://cuke.hort.ncsu.edu/cucurbit/wmelon/wmelonmain.html. | Mahendra Dia Todd C Wehner Penelope Perkins-Veazie Richard Hassell Daniel S Price George E Boyhan Stephen M Olson Stephen R King Angela R Davis Gregory E Tolla Jerome Bernier Benito Juarez | 2016 | Horticulture Research2016，3，1： | 2 |
| 5 | Idiopathic pulmonary fibrosis显示文摘 | Talmadge E King Annie Pardo Moisés Selman | 2011 | The Lancet . 2011 (9807)2011，，： | 2 |
| 6 | SchrSdinger cat superposition state of an atom 显示文摘 | Monroe C Meekhof D M King B E | 1996 | Science1996，272，： | 1 |
| 7 | Intensity-based protein identification by machine learning from a library of tandem mass spectra显示文摘 | Elias J E Gibbons F D King O D | 2004 | Nature Biotechnology2004，22，： | 1 |
| 8 | Identification of PKC-isoformspecific biological actions using pharmacological approaches显示文摘 | Chou E King GL | 2000 | Trends Pharmacol Sci2000，21，： | 1 |
| 9 | Prior Political Experience and Gubernatorial Popularity 显示文摘 | King J D Hamman J A Cohen J E | 2005 | Presented at the Fifth Annual State Polities and Policy Conference East Lansing Michigan2005，，： | 1 |
| 10 | Recent developments in acute myelogenous leukemia therapy 显示文摘 | King M E Rowe J M | 2007 | Oncologist2007，12，2： | 1 |
| 11 | Schematic method of deriving the rate laws for enzyme-catalyzed reactions显示文摘 | King E L Altman C A | 1956 | J Phys Chem1956，60，： | 1 |
| 12 | Augmendation of parasites and predators for suppression of arthropod pests 显示文摘 | King E C | 1993 | Proceeding of Beltsville Symposium1993，28，： | 1 |
| 13 | Spatial analysis of radiometric fractions from high-resolution multispectral imagery for modelling individual tree crown and forest canopy structure and health显示文摘 | Jose′e Le′vesquea Douglas King J | 2003 | Remote Sensing of Environment2003，84，： | 1 |
| 14 | An Energy-based formulation for computing nonlinear normal modes in undamped continuous systems显示文摘 | King M E Vakakis A F | 1994 | Transactions of the ASME Journal of Vibration and Acoustics1994，11，6： | 1 |
| 15 | Generation of Nonclassical Motional States of a Trapped Atom 显示文摘 | MEEKHOF D M MONROE C KING B E | 1996 | Phys Rev Lett1996，76，： | 1 |
| 16 | Global burden of diabetes 1995- 2025 prevalence, numerical estimates and projections显示文摘 | King H Aubert R E Herman W H | 1998 | Diabetes care1998，21，： | 1 |
| 17 | Modeling yarn slip in woven fabric at the continuum level: Simulations of ballistic impact 显示文摘 | E M Parsons M J King S Socrale | 2013 | Journal of the Mechanics and Physics of Solids2013，61，1： | 1 |
| 18 | Strategic environmental noise mapping:Methodological issues concerning the implementation of the EU Environmental Noise Directive and their policy implications显示文摘 | E A King E Murphy | | 0，，03： | 1 |
| 19 | Amino acid composition of germinating cotton seeds 显示文摘 | ELMORE C D KING E E | 1978 | Plant Physiol1978，62，4： | 1 |
| 20 | Idiopathic pul-monary fibrosis:prevailing and evolving hypotheses a- bout its pathogenesis and implications for therapy 显示文摘 | SELMAN M KING T E PARDO A | 2001 | Ann Intern Med2001，134，2： | 1 |
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