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| 1 | Effect of PA-MSHA vaccine on plasma phospholipids metabolic profiling and the ratio of Th2/Thl cells within immune organ of mouse IgA nephropathy显示文摘 | Jia, LW Wang, C Kong, HW Yang, J Li, FL Lv, S Xu, GW | 2007 | 中国生物学文摘2007，21，11： | 19 |
| 2 | Measurement and Prediction of Insertion Force for the Mosquito Fascicle Penetrating into Human Skin显示文摘Mosquitoes are exceptional in their ability to pierce into human skin with a natural ultimate painless microneedle, namedfascicle. Here the structure of the Aedes albopictus mosquito fascicle is obtained using a Scanning Electron Microscope (SEM),and the whole process of the fascicle inserting into human skin is observed using a high-speed video imaging technique. Directmeasurements of the insertion force for mosquito fascicle to penetrate into human skin are reported. Results show that themosquito uses a very low force (average 18 μN) to penetrate into the skin. This force is at least three orders of magnitude smallerthan the reported lowest insertion force for an artificial microneedle with an ultra sharp tip to insert into the human skin. In orderto understand the piercing mechanism of mosquito fascicle tip into human multilayer skin tissue, a numerical simulation isconducted to analyze the insertion process using a nonlinear finite element method. A good agreement occurs between thenumerical results and the experimental measurements. | X Q Kong C W Wu | 2009 | Journal of Bionic Engineering2009，6，2： | 12 |
| 3 | Grain Size and Wettability of TiO_2/SiO_2 Photocatalytic Composite Thin Filing显示文摘The uniform transparent TiO2/SiO2 photocatalytic composite thin films are prepared by sol-gel method on the soda lime glass substrates, and characterized by UV-visible spectroscopy, X-ray diffraction (XRD), transmission electron microscopy (TEM), BET surface area, FTIR spectroscopy and X-ray photoelectron spectroscopy (XPS). It was found that the addition of SiO2 to TiO2 thin films can suppress the grain growth of TiO2 crystal, increase the hydroxyl content on the surface of TiO2 films, lower the contact angle for water on TiO2 films and enhance the hydrophilic property of TiO2 films. The super-hydrophilic TiO2/SiO2 photocatalytic composite thin films with the contact angle of 0° are obtained by the addition of 10%-20% SiO2 in mole fraction. | Jiaguo Yu, Xiujian Zhao, Jimmy C Yu, Jun Lin (State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China Deportment of Chemised The Chinese University of Hong Kong, Hong Kong, | 2001 | Rare Metals2001，20，2： | 11 |
| 4 | A Novel Semiconductor CIGS Photovoltaic Material and Thin-Film ED Technology显示文摘In order to achieve low cost high efficiency thin film solar cells,a novel Semiconductor Photovoltaic (PV) active material CuIn 1-x Ga x Se 2 (CIGS) and thin film Electro Deposition (ED) technology is explored.Firstly,the PV materials and technologies is investigated,then the detailed experimental processes of CIGS/Mo/glass structure by using the novel ED technology and the results are reported.These results shows that high quality CIGS polycrystalline thin films can be obtained by the ED method,in which the polycrystalline CIGS is definitely identified by the (112),(204,220) characteristic peaks of the tetragonal structure,the continuous CIGS thin film layers with particle average size of about 2μm of length and around 1 6μm of thickness.The thickness and solar grade quality of CIGS thin films can be produced with good repeatability.Discussion and analysis on the ED technique,CIGS energy band and sodium (Na) impurity properties,were also performed.The alloy CIGS exhibits not only increasing band gap with increasing x ,but also a change in material properties that is relevant to the device operation.The beneficial impurity Na originating from the low cost soda lime glass substrate becomes one prerequisite for high quality CIGS films.These novel material and technology are very useful for low cost high efficiency thin film solar cells and other devices. | ZHENG Guang fu 1,YANG Hong xing 1,MAN Cheuk ho 1,WONG Wing lok 2, AN Da wei 1 and John BURNETT 1(1 Centre for Development of Solar Energy Technology,Department of Building Services Engineering, The Hong Kong Polytechnic University,Hong Kong,C | 2001 | Journal of Semiconductors2001，22，11： | 10 |
| 5 | High-resolution microendoscopy for esophageal cancer screening in China: A cost-effectiveness analysis显示文摘AIM:To study the cost-effectiveness of high-resolution microendoscopy(HRME)in an esophageal squamous cell carcinoma(ESCC)screening program in China.METHODS:A decision analytic Markov model of ESCC was developed.Separate model analyses were conducted for cohorts consisting of an averagerisk population or a high-risk population in China.Hypothetical 50-year-old individuals were followed until age 80 or death.We compared three different strategies for both cohorts:(1)no screening;(2)standard endoscopic screening with Lugol’s iodine staining;and(3)endoscopic screening with Lugol’s iodine staining and an HRME.Model parameters were estimated from the literature as well as from GLOBOCAN,the Cancer Incidence and Mortality Worldwide cancer database.Health states in the model included non-neoplasia,mild dysplasia,moderate dysplasia,high-grade dysplasia,intramucosal carcinoma,operable cancer,inoperable cancer,and death.Separate ESCC incidence transition rates were generated for the average-risk and high-risk populations.Costs in Chinese currency were converted to international dollars(I$)and were adjusted to 2012dollars using the Consumer Price Index.RESULTS:The main outcome measurements for this study were quality-adjusted life years(QALYs)and incremental cost-effectiveness ratio(ICER).For the average-risk population,the HRME screening strategy produced 0.043 more QALYs than the no screening strategy at an additional cost of I$646,resulting in an ICER of I$11808 per QALY gained.Standard endoscopic screening was weakly dominated.Among the high-risk population,when the HRME screening strategy was compared with the standard screening strategy,the ICER was I$8173 per QALY.For both the high-risk and average-risk screening populations,the HRME screening strategy appeared to be the most cost-effective strategy,producing ICERs below the willingness-topay threshold,I$23500 per QALY.One-way sensitivity analysis showed that,for the average-risk population,higher specificity of Lugol’s iodine(>40%)and lower specificity of HRME(<70%)could make Lugol’s iodine screening cost-effective.For the high-risk population,the results of the model were not substantially affected by varying the follow-up rate after Lugol’s iodine screening,Lugol’s iodine test characteristics(sensitivity and specificity),or HRME specificity.CONCLUSION:The incorporation of HRME into an ESCC screening program could be cost-effective in China.Larger studies of HRME performance are needed to confirm these findings. | Chin Hur Sung Eun Choi Chung Yin Kong Gui-Qi Wang Hong Xu Alexandros D Polydorides Li-Yan Xue Katherine E Perzan Angela C Tramontano Rebecca R Richards-Kortum Sharmila Anandasabapathy | 2015 | World Journal of Gastroenterology2015，21，18： | 8 |
| 6 | 包括p16、ProExC或HPV原位杂交在内的一组3个标记物最适于区分原发性子宫内膜腺癌和宫颈腺癌显示文摘 | Kong C S Beck A H Longacre T A 黄文斌(摘译) | 2010 | 临床与实验病理学杂志2010，26，5： | 7 |
| 7 | Primary squamous cell carcinoma of the rectum: An update and implications for treatment显示文摘AIM: To provide an update on the aetiology, pathogenesis, diagnosis, staging and management of rectal squamous cell carcinoma(SCC).METHODS: A systematic review was conducted according to the preferred reporting items for Systematic Reviews and Meta-Analyses guidelines. A comprehensive search of Ovid MEDLINE was performed with the reference list of selected articles reviewed to ensure all relevant publications were captured. The search strategy was limited to the English language, spanning from 1946 to 2015. A qualitative analysis was undertaken examining patient demographics, clinical presentation, diagnosis, staging, treatment and outcome. The quantitaive analysis was limited to data extracted on treatment and outcomes including radiological, clinical and pathological complete response where available. The narrative and quantitative review were synthesised in concert.RESULTS: The search identified 487 articles in total with 79 included in the qualitative review. The quantitative analysis involved 63 articles, consisting of 43 case reports and 20 case series with a total of 142 individual cases. The underlying pathogenesis of rectal SCC while unclear, continues to be defined, with increasing evidence of a metaplasia-dysplasia-carcinoma sequence and a possible role for human papilloma virus in this progression. The presentation is similar to rectal adenocarcinoma, with a diagnosis confirmed by endoscopic biopsy. Many presumed rectal SCC's are in fact an extension of an anal SCC, and cytokeratin markers are a useful adjunct in this distinction. Staging is most accurately reflected by the tumour-nodemetastasis classification for rectal adenocarcinoma. It involves examining locoregional disease by way of magnetic resonance imaging and/or endorectal ultrasound, with systemic spread excluded by way of computed tomography. Positron emission tomography is integral in the workup to exclude an external siteof primary SCC with metastasis to the rectum. While the optimal treatment remains as yet undefined, recent studies have demonstrated a global shift away from surgery towards definitive chemoradiotherapy as primary treatment. Pooled overall survival was calculated to be 86% in patients managed with chemoradiation compared with 48% for those treated traditionally with surgery. Furthermore, local recurrence and metastatic rates were 25% vs 10% and 30% vs 13% for the chemoradiation vs conventional treatment cohorts.CONCLUSION: The changing paradigm in the treatment of rectal SCC holds great promise for improved outcomes in this rare disease. | Glen R Guerra Cherng H Kong Satish K Warrier Andrew C Lynch Alexander G Heriot Samuel Y Ngan | 2016 | World Journal of Gastrointestinal Surgery2016，8，3： | 5 |
| 8 | 流感病毒传播能力相关遗传机制的深度解析显示文摘在人与人之间通过呼吸道高效传播的能力是新发流感病毒引起人流感大流行的先决条件,但流感病毒传播能力遗传决定因素至今并不完全清楚。揭示流感病毒传播能力遗传机制对人流感大流行的预警以及防控疫苗和药物研发都至关重要,因此一直是病毒学领域研究的重点。2013年出现在我国的H7N9亚型禽流感病毒已导致1560多人感染,致死率近40%。 | Kong H Ma S Wang J Gu C | 2019 | 中国预防兽医学报2019，41，11： | 5 |
| 9 | 中国慢性病的挑战与应对显示文摘中国在短短几十年内,完成了从传染病向慢性病的流行病学模式转变,转变速度远远高于其他许多国家。而行为模式的转变,包括膳食习惯变化、体力活动减少、高水平的男性吸烟率等危险因素是中国疾病模式快速转变的重要原因。其结果是,这些本可避免的慢性病的发病率和死亡率快速上升。引发了医疗卫生服务费用显著上升。目前,中国有1.77亿高血压患者,有3.03亿烟民(占世界烟民的1/3),并有5.3亿人遭受被动吸烟危害。 | Gonghuan Yang Lingzhi Kong Wenhua Zhao Xia Wan Yi Zhai Lincoln C Chen Jeffrey P Koplan | 2008 | 世界临床医学2008，2，6： | 5 |
| 10 | 成人脊柱畸形环形微创手术矫形分期治疗方案显示文摘为降低开放手术并发症的发生风险,过去十余年人们一直致力于成人脊柱畸形(adult spinal deformity,ASD)微创手术(minimally invasive surgery,MIS)方法的研究。在众多微创术式中,环形MIS(circumferential MIS,cMIS)相对于常规开放手术,可有效发挥微创优势。我们采用最新cMIS手术方案治疗1例严重ASD患者,并对其术前评估、手术规划及优化术式选择进行了总结。术前评估包括详细病史采集、体格检查及影像学检查等。其中影像学检查有站立位全脊柱X线检查(测量患者畸形程度和脊柱骨盆参数)、MRI检查(评估椎管狭窄情况,确保无椎间盘碎片游离于椎管内),如疑有节段融合,则需行CT扫描,以观察关节面融合或椎体间融合情况,指导椎间融合器的合理应用,实现对脊柱矫形手术的有效干预。cMIS手术分两期进行,一期经斜外侧微创入路行腰椎椎间融合,融合范围包括参与测量Cobb角的所有节段。上端椎水平位于X线片及MRI中第一个正常平行椎间盘的下位椎体;远端如有局部椎管狭窄,椎体不稳、倾斜或退行性变,矢状面失衡超过10 cm或骨质疏松,则可将融合范围延长至L5~S1水平。患者一期手术结束后当天即可下地行走,术后2 d或3 d复查站立位X线片,可根据新的影像学测量参数适当调整手术方案。一期术后2~3 d开始做二期手术,对涉及的所有节段行经皮椎弓根螺钉固定,置钉同时经肌间隙显露相应的椎弓根峡部及关节突关节,对其进行去皮质操作,以实现胸椎节段的后路融合。 | Anand N Kong C Fessler RG 梁达轩 吴增晖 | 2017 | 中国骨科临床与基础研究杂志2017，9，6： | 4 |
| 11 | ZrO_2 strengthened NiAl/Cr(Mo,Hf) composite fabricated by powder metallurgy | L.Y. Sheng a,b, J.T. Guo c, T.F. Xi a,b, B.C. Zhang c, H.Q. Ye c a PKU-HKUST ShenZhen-Hong Kong Institution, Shenzhen 518057, China b College of Engineering, Peking University, Beijing 100871, China c Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China | 2012 | Progress in Natural Science:Materials International2012，22，3： | 3 |
| 12 | 云南省农村地区男男性接触者与HIV相关的风险行为显示文摘目的探讨中国农村地区男男性接触者(MSM)与艾滋病病毒(HIV)相关的风险行为的具体特点和问题。方法采用半结构化深度访谈的方式进行定性研究。通过一个当地的MSM联系网络,以滚雪球和相互转告的方式招集了24名访谈对象。主要测量指标是与HIV有关的风险行为的上升情况。结果在中国农村地区,风险行为、社会歧视、独生子女政策以及传统中医的观念,在HIV的传播中都起着重要的作用。在中国,许多MSM过着双重生活;调查显示,安全套的使用情况也是因人而异,使风险行为'合理化'的意图是决定是否使用安全套的主要因素;就泌尿生殖系统的问题主动寻求医疗帮助的现象很不普遍,而现有卫生系统以及医务人员对此问题表现出来的不敏感,也进一步加剧了这种现象。结论在资源匮乏的农村地区,MSM人群存在着HIV流行的趋势,并有向普通人群传播的危险。 | 张建波 黄志威 T S K Kong D C Y Ling | 2007 | 中国艾滋病性病2007，13，5： | 3 |
| 13 | Simultaneous measurement of strain and temperature: graphical representation显示文摘Simultaneousmeasurementofstrainandtemperature:graphicalrepresentation⒇WJin(Dept.Electr.Eng.,HongKongPolytechnicUniv.)WCMichie... | W Jin (Dept. Electr. Eng., Hong Kong Polytechnic Univ. ) W C Michie, G Thursby, M Konstantaki, B Culshaw (Optoelectron. Div., Univ. of Strathclyde, Glasgow, UK) | 1997 | 大连理工大学学报1997，37，S2： | 3 |
| 14 | The Novel Mechanical Property of Tongue of a Woodpecker显示文摘Biomaterials such as bone,teeth,nacre and silk are known to have superior mechanical properties due to their specificnanocomposite structures.Here we report that the woodpecker’s tongue exhibits a novel strength and flexibility due to its specialcomposite micro/nanostructure.The tongue consists of a flexible cartilage-and-bone skeleton covered with a thin layer tissue ofhigh strength and elasticity.At the interface between the cartilage-and-bone skeleton and the tissue layer,there is a hierarchicalfiber-typed connection.It is this special design of the tongue that makes the woodpeckers efficient in catching the insects insidetrees.The special micro/nanostructures of the woodpecker’s tongue show us a potential method to enhance the interfacialconnection between soft and hard material layers for bio-inspired composite system designs. | P Zhou X Q Kong C W Wu Z Chen | 2009 | Journal of Bionic Engineering2009，6，3： | 3 |
| 15 | Objective evaluation correlated with human judgment-an approach to the optimization of vehicle handling control system显示文摘 | GUO K H ZONG C F KONG F S | 2002 | International Journal of Vehicle Design2002，29，1： | 2 |
| 16 | Stable expression of primary human immunodeficiency virus type 1 structural gene products by use of a noncytopathic Sindbis virus vector显示文摘 | Kong W Tian C J Liu B D | 2002 | J Virol2002，76，11： | 2 |
| 17 | Quantitative X-ray diffraction analysis and its application to various coals显示文摘 | L Lu V Sahajwalla C Kong D Harris | 2001 | Carbon2001，，12： | 2 |
| 18 | Kinematics and singularity analysis of a novel type of 3 - CRR 3 - DOF translational parallel manipulator 显示文摘 | Kong Xianwen Gosselin C M | 2002 | International Journal of Robotics Research2002，21，9： | 1 |
| 19 | Prognostic implication of creatine kinase elevation following elective coronary interventions 显示文摘 | Kong TQ Davidson C J Meyers SN et aI | 1997 | JAMA1997，277，6： | 1 |
| 20 | Risk factors for procedure related fetal losses after mid-trimester genetic amnio-centesis显示文摘 | KONG C W LEUNG T N LEUNG T Y et a1 | 2006 | Prenat Diagn2006，26，10： | 1 |
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