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| 1 | Endoscopic submucosal dissection vs endoscopic mucosal resection for colorectal polyps:A meta-analysis and metaregression with single arm analysis显示文摘BACKGROUND Endoscopic submucosal dissection(ESD)has shown to be effective in management of colorectal neoplasm in the Asian countries,while its implementation in Western countries where endoscopic mucosal resection(EMR)is preferred is still debatable.AIM To compare the surgical,histological,and oncological outcomes between ESD and EMR in the treatment of colorectal polyps,with subgroup analysis comparing the efficacy of ESD and EMR between Japan and the rest of the world.METHODS Embase and Medline databases were searched from inception to October 2020 in accordance with PRISMA guidelines for studies comparing en bloc,complete resection,margin involvement,resection time,need for additional surgery,complications,and recurrence rate of ESD with EMR.RESULTS Of 281344 colorectal polyps from 21 studies were included.When compared to EMR,the pooled analysis revealed ESD was associated with higher en bloc and complete resection rate,and lower lateral margin involvement and recurrence.ESD led to increased procedural time,need for additional surgery,and perforation risk.No significant difference in bleeding risk was found between the two groups.Meta-regression analysis suggested only right colonic polyps correlated with an increased perforation risk in ESD.Confounders including polyp size and invasion depth did not significantly influence the en bloc and complete resection rate,bleeding risk and recurrence.In subgroup analysis,Japan performed better than the rest of the world in both ESD and EMR with perforation risk of 4%and 0.0002%,respectively,as compared to perforation risk of 8%and 1%,respectively,in reports coming from rest of the world.CONCLUSION ESD resulted in better resection outcomes and lower recurrence compared to EMR.With appropriate training,ESD is preferred over EMR as the first-line therapy for resection of colorectal polyps,without restricting to lesions greater than 20 mm and those with high suspicion of submucosal invasion. | Xiong Chang Lim Kameswara Rishi Yeshayahu Nistala Cheng Han Ng Snow Yunni Lin Darren Jun Hao Tan Khek-Yu Ho Choon-Seng Chong Mark Muthiah | 2021 | World Journal of Gastroenterology2021，27，25： | 4 |
| 2 | Safety of glass panels against wind loads显示文摘 | Kameswara Rao C V S | 1984 | Engineering Structures1984，6，： | 1 |
| 3 | Finding the core point in a fingerprint显示文摘 | Kameswara Rao C V Balck Kenneth | 1978 | IEEE Transactions on Computers1978，27，1： | 1 |
| 4 | Effect of Pterocarpus santalinus bark, on blood glucose, serum lipids, plasma insulin and hepatic carbohydrate metabolic enzymes in streptozotocin-induced diabetic rats显示文摘 | Vinay Kumar Kondeti Kameswara Rao Badri Dilip Rajasekhar Maddirala Sampath Kumar Mekala Thur Shaik Sameena Fatima Ramesh Babu Kasetti Chippada Appa Rao | 2010 | Food and Chemical Toxicology2010，，5： | 1 |
| 5 | Lipid peroxidationand antioxidant enzyme levels in type 2 diabetics with microvascu-lar complications显示文摘 | Kesavulu MM Giri R Kameswara Rao B | 2000 | Diabetes Metab2000，26，5： | 1 |
| 6 | Effect of sulfates on the setting time of cement and strength of concrete 显示文摘 | KUMAR S KAMESWARA RAO C V S | 1994 | Cem Concr Res1994，24，7： | 1 |
| 7 | Antidiabetic and hypolipidemic effects of Momordica cymbalaria Hook fruit powder in alloxan diabetic rats显示文摘 | Kameswara Rao B Kesavulu M M Giri R | 1999 | J Ethnophar1999，67，： | 1 |
| 8 | Antidiabetic and hypolipidemic effects of Momordica cymbalaria Hook. fruit powder in alloxan-diabetic rats显示文摘 | B Kameswara Rao M.M Kesavulu R Giri Ch Appa Rao | 1999 | Journal of Ethnopharmacology1999，，1： | 1 |
| 9 | Effect of resin modification on friction and wear phenolic composites显示文摘 | Verma A P Vishwanath B Kameswara Rao C V S | 1996 | Wear1996，193，2： | 1 |
| 10 | Fire load in residential buildings显示文摘 | KUMAR S KAMESWARA R | 1995 | Buildittg and Environment1995，30，2： | 1 |
| 11 | Extended Fractal Feature for First Stage SAR Target Detection 显示文摘 | KAPLAN L M ROMAIN M KAMESWARA N | 1999 | SPIE1999，3721，： | 1 |
| 12 | Variation in seed longevity of rice cultivars belonging to different isozyme groups 显示文摘 | KAMESWARA N JACHSON M T | 1997 | Genetic Resources and Crop Evolution1997，44，： | 1 |
| 13 | Fire load in residential build- ings显示文摘 | Sunil Kumar Kameswara C V S K | 1995 | Building and Environment1995，30，2： | 1 |
| 14 | Response of soil media due to impulse loads and isolation using trenches显示文摘 | Shrivastavaa R K Kameswara Rao N S V | 2002 | Soil Dynamics and Earthquake Engineering2002，22，8： | 1 |
| 15 | Plant genetic resources: Advancing conservation and use through biotechnology显示文摘 | Kameswara N | 2004 | African Journal of Biotechnology2004，3，2： | 1 |
| 16 | Effect of resin modification on friction and wear of glass phenolic composites显示文摘 | Verma A P Vishwanath B Kameswara R | 1996 | Wear1996，4，4： | 1 |
| 17 | Processing of liquid propellant reaction liquors by pervaporation 显示文摘 | Ravindra R Kameswara R A Khan A A | 1999 | Journal of Applied Polymer Science1999，72，1： | 1 |
| 18 | Four new lobane diterpenoids from the soft coral Lobophytum microlobulatum of the Havellock Island of the Andaman and Nicobar group of Islands显示文摘 | Anjaneyulu ASR Kameswara Rao NS | 1996 | Indian J Chem1996，35，： | 1 |
| 19 | Response of soil media due to impulse loads and isolation using trenches显示文摘 | SHRIVASTAVA R K KAMESWARA RAO N S V | 2002 | Soil Dynamics and Earthquake Engineering2002，22，8： | 1 |
| 20 | Finding the Core Point in a Fingerprint显示文摘 | C V Kameswara Rao Kenneth Balck | 1978 | IEEE Transactions on computers1978，27，1： | 1 |
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