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| 1 | In-situ formation of MOF derived mesoporous Co3N/amorphous N-doped carbon nanocubes as an efficient electrocatalytic oxygen evolution reaction显示文摘The suitable materials,metal nitrides,are a promising class of electrocatalyst materials for a highly efficient oxygen evolution reaction (OER) because they exhibit superior intrinsic conductivity and have higher sustainability than oxide-based materials.To our knowledge,for the first time,we report a designable synthesis of three-dimensional (3D) and mesoporous Co3N@ amorphous N-doped carbon (AN-C) nanocubes (NCs) with well-controlled open-framework structures via monodispersed Co3[Co(CN)6]2 Prussian blue analogue (PBA) NC precursors using in situ nitridation and calcination processes.Co3N@AN-C NCs (2 h) demonstrate better OER activity with a remarkably low Tafel plot (69.6 mV-dec-1),low overpotential of 280 mV at a current density of 10 mA-crrf2.Additionally,excellent cycling stability in alkaline electrolytes was exhibited without morphological changes and voltage elevations,superior to most reported hierarchical structures of transition-metal nitride particles.The presented strategy for synergy effects of metal-organic frameworks (MOFs)-derived transition-metal nitrides-carbon hybrid nanostructures provides prospects for developing high-performance and advanced electrocatalyst materials. | Bong Kyun Kang Seo Young Im Jooyoung Lee Sung Hoon Kwag Seok Bin Kwon SintayehuNibret Tiruneh Min-Jun Kim Jung Ho Kim Woo Seok Yang Byungkwon Lim Dae Ho Yoon | 2019 | Nano Research2019，12，7： | 8 |
| 2 | Two-dimensional physical habitat modeling of effects of habitat structures on urban stream restoration显示文摘River corridors, even if highly modified or degraded, still provide important habitats for numerous biological species, and carry high aesthetic and economic values. One of the keys to urban stream restoration is recovery and maintenance of ecological flows sufficient to sustain aquatic ecosystems. In this study, the Hongje Stream in the Seoul metropolitan area of Korea was selected for evaluating a physically-based habitat with and without habitat structures. The potential value of the aquatic habitat was evaluated by a weighted usable area (WUA) using River2D, a two-dimensional hydraulic model. The habitat suitability for Zacco platypus in the Hongje Stream was simulated with and without habitat structures. The computed WUA values for the boulder, spur dike, and riffle increased by about 2%, 7%, and 131%, respectively, after their construction. Also, the three habitat structures, especially the riffle, can contribute to increasing hydraulic heterogeneity and enhancing habitat diversity. | Dongkyun IM Hyeongsik KANG | 2011 | Water Science and Engineering2011，4，4： | 8 |
| 3 | Clinical and endoscopic characteristics of drug-induced esophagitis显示文摘AIM: To investigate clinical, endoscopic and pathological characteristics of drug-induced esophagitis.METHODS: Data for patients diagnosed with drug-induced esophagitis from April 2002 to May 2013 was reviewed. Patients diagnosed with malignancy, viral or fungal esophagitis were excluded. Clinical, endoscopic and pathological characteristics of patients diagnosed with drug-induced esophagitis were analyzed.RESULTS: Seventy-eight patients were diagnosed with drug-induced esophagitis. Their mean age was 43.9 ± 18.9 years and 35.9% were male. Common symptoms were chest pain(71.8%), odynophagia(38.5%) and dysphagia(29.5%). The endoscopic location was in the middle third of esophagus in 78.2%. Endoscopic findings were ulcer(82.1%), erosion(17.9%), ulcer with bleeding(24.4%), coating with drug material(5.1%), impacted pill fragments(3.8%) and stricture(2.6%). Kissing ulcers were observed in 43.6%. The main causative agents were antibiotics and non-steroidal antiinflammatory drugs. All the patients were treated with proton pump inhibitors(PPIs) or sucralfate, and the causative drugs were discontinued. Nineteen patients with drug-induced esophagitis were followed up with endoscopy and revealed normal findings, scars or healing ulcers.CONCLUSION: Drug-induced esophagitis mainly presents as chest pain, odynophagia and dysphagia, and may be successfully treated with PPIs and discontinuation of the causative drug. Kissing ulcers were observed in 43.6%. | Su Hwan Kim Ji Bong Jeong Ji Won Kim Seong-Joon Koh Byeong Gwan Kim Kook Lae Lee Mee Soo Chang Jong Pil Im Hyoun Woo Kang Cheol Min Shin | 2014 | World Journal of Gastroenterology2014，20，31： | 7 |
| 4 | Bilateral primary breast lymphoma显示文摘 | Jung Im Yi Byung Joo Chae Ja Seong Bae Bong Joo Kang Ahwon Lee Byung Joo Song Sang Seol Jung | 2010 | Chinese Medical Journal2010，，11： | 5 |
| 5 | Periodontitis combined with smoking increases risk of the ulcerative colitis: A national cohort study显示文摘BACKGROUND Periodontitis is a chronic inflammation of periodontal tissues.The effect of periodontitis on the development of inflammatory bowel disease(IBD)remains unclear.AIM To assessed the risk of IBD among patients with periodontitis,and the risk factors for IBD related to periodontitis.METHODS A nationwide population-based cohort study was performed using claims data from the Korean National Healthcare Insurance Service.In total,9950548 individuals aged≥20 years who underwent national health screening in 2009 were included.Newly diagnosed IBD[Crohn’s disease(CD),ulcerative colitis(UC)]using the International Classification of Disease 10th revision and rare intractable disease codes,was compared between the periodontitis and nonperiodontitis groups until 2017.RESULTS A total of 1092825 individuals(11.0%)had periodontitis.Periodontitis was significantly associated with older age,male gender,higher body mass index,quitting smoking,not drinking alcohol,and regular exercise.The mean age was 51.4±12.9 years in the periodontitis group and 46.6±14.2 years in the nonperiodontitis group(P<0.01),respectively.The mean body mass index was 23.9±3.1 and 23.7±3.2 in the periodontitis and non-periodontitis groups,respectively(P<0.01).Men were 604307(55.3%)and 4844383(54.7%)in the periodontitis and non-periodontitis groups,respectively.The mean follow-up duration was 7.26 years.Individuals with periodontitis had a significantly higher risk of UC than those without periodontitis[adjusted hazard ratio:1.091;95%confidence interval(CI):1.008-1.182],but not CD(adjusted hazard ratio:0.879;95%confidence interval:0.731-1.057).The risks for UC were significant in the subgroups of age≥65 years,male gender,alcohol drinker,current smoker,and reduced physical activity.Current smokers aged≥65 years with periodontitis were at a 1.9-fold increased risk of UC than non-smokers aged≥65 years without periodontitis.CONCLUSION Periodontitis was significantly associated with the risk of developing UC,but not CD,particularly in current smokers aged≥65 years. | Eun Ae Kang Jaeyoung Chun Jee Hyun Kim Kyungdo Han Hosim Soh Seona Park Seung Wook Hong Jung Min Moon Jooyoung Lee Hyun Jung Lee Jun-Beom Park Jong Pil Im Joo Sung Kim | 2020 | World Journal of Gastroenterology2020，26，37： | 3 |
| 6 | Prostate calculi in cancer and BPH in a cohort of Korean men:presence of calculi did not correlate with cancer risk显示文摘Prostatic 演算是普通的并且与前列腺的发炎被联系。最近,这发炎可以与前列腺 carcinogenesis 被联系,这被建议了。这研究的目的是在前列腺活体检视标本调查在 prostatic 演算和前列腺癌症(PCa ) 之间的关系。我们回顾地分析了经历了 transrectal ultrasonography (TRUS ) 和在 2005 年 1 月和 2008 年 1 月之间的前列腺活体检视的 417 个连续病人。基于活体检视调查结果,病人们被划分成良性的 prostatic 增生和 PCa 组。TRUS 被用来检测 prostatic 演算并且测量前列腺体积。在 PCa 风险和年龄,浆液总数 PSA 层次,前列腺体积,和 prostatic 演算之间的关联被分析。耐心的年龄和 PSA,以及在活体检视标本的 prostatic 演算的频率,在两个之间显著地不同这些组(P < 0.05 ) 。在 PCa 组,没有 prostatic 演算,格利森分数(GS ) 比在病人在有 prostatic 演算的病人是更高的(P = 0.023 ) 。用 multivariate 逻辑回归分析,我们发现了那耐心的年龄,浆液总数 PSA 和前列腺体积是为 PCa 的风险因素(P = 0.001 ) ,但是 prostatic 演算的存在没与 PCa 的增加的风险被联系(P = 0.13 ) 。在结论,尽管 prostatic 演算的存在没被显示是为 PCa 的一个风险因素, prostatic 演算在有 PCa 的病人是更普通的并且在这些人之中与更高的 GS 被联系。 | Eu-Chang Hwang Hyang-Sik Choi Chang-Min Im Seung-II Jung Sun-Ouck Kim Tack-Won Kang Dong-Deuk Kwon Kwang-Sung Park Soo-Bang Ryu | 2010 | Asian Journal of Andrology2010，12，2： | 3 |
| 7 | The growth inhibitory effect of lapatinib, a dual inhibitor of EGFR and HER2 tyrosine kinase, in gastric cancer cell lines显示文摘 | Jin Won Kim Hwang-Phill Kim Seock-Ah Im Soyeong Kang Hyung Seok Hur Young-Kwang Yoon Do-Youn Oh Jee Hyun Kim Dong Soon Lee Tae-You Kim Yung-Jue Bang | 2008 | Cancer Letters2008，，2： | 2 |
| 8 | Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer显示文摘 | Sae‐Won Han Hyun‐Jung Lee Jeong Mo Bae Nam‐Yun Cho Kyung‐Hun Lee Tae‐Yong Kim Do‐Youn Oh Seock‐Ah Im Yung‐Jue Bang Seung‐Yong Jeong Kyu Joo Park Jae‐Gahb Park Gyeong Hoon Kang Tae‐You Kim | 2012 | Int J Cancer2012，，9： | 2 |
| 9 | Flexible thermocells for utilization of body heat显示文摘 | Hyeongwook Im Hyung Geun Moon Jeong Seok Lee In Young Chung Tae June Kang Yong Hyup Kim | 2014 | Nano Research2014，7，4： | 2 |
| 10 | Trends and risk factors of elderly-onset Crohn’s disease: A nationwide cohort study显示文摘BACKGROUND The incidence of inflammatory bowel disease(IBD)is increasing in Asia.Numerous risk factors associated with IBD development have been investigated.AIM To investigate trends and environmental risk factors of Crohn’s disease(CD)diagnosed in persons aged≥40 years in South Korea.METHODS Using the National Health Insurance Service database,a total of 14060821 persons aged>40 years who underwent national health screening in 2009 were followed up until December 2017.Patients with newly diagnosed CD were enrolled and compared with non-CD cohort.CD was identified according to the International Classification of Diseases 10th revision and the rare/intractable disease registration program codes from the National Health Insurance Service database.The mean follow-up periods was 7.39 years.Age,sex,diabetes,hypertension,smoking,alcohol consumption,regular exercise,body mass index,anemia,chronic kidney disease(CKD)and dyslipidemia were adjusted for in the multivariate analysis model.RESULTS During the follow-up,1337(1.33/100000)patients developed CD.Men in the middle-aged group(40-64 years)had a higher risk than women[adjusted hazard ratio(aHR)1.46,95%confidence interval(CI):1.29-1.66];however,this difference tended to disappear as the age of onset increases.In the middle-aged group,patients with a history of smoking[(aHR 1.46,95%CI:1.19-1.79)and anemia(aHR 1.85,95%CI:1.55-2.20)]had a significantly higher CD risk.In the elderly group(age,≥65 years),ex-smoking and anemia also increased the CD risk(aHR 1.68,95%CI:1.22-2.30)and 1.84(95%CI:1.47-2.30,respectively).Especially in the middle-aged group,those with CKD had a statistically elevated CD risk(aHR 1.37,95%CI:1.05-1.79).Alcohol consumption and higher body mass index showed negative association trend with CD incidence in both of the age groups.[Middle-aged:aHR 0.77(95%CI:0.66-0.89)and aHR 0.73(95% CI:0.63-0.84),respectively][Elderly-group:aHR 0.57(95% CI:0.42-0.78)and aHR 0.84(95%CI 0.67-1.04),respectively].For regular physical activity and dyslipidemia,negative correlation between CD incidences was proved only in the middle-aged group[aHR 0.88(95%CI:0.77-0.89)and aHR 0.81(95%CI:0.68-0.96),respectively].CONCLUSION History of cigarette smoking,anemia,underweight and CKD are possible risk factors for CD in Asians aged>40 years. | Jung Min Moon Eun Ae Kang Kyungdo Han Seung Wook Hong Hosim Soh Seona Park Jooyoung Lee Hyun Jung Lee Jong Pil Im Joo Sung Kim | 2020 | World Journal of Gastroenterology2020，26，4： | 2 |
| 11 | Inhibition of BET selectively eliminates undifferentiated pluripotent stem cells显示文摘Embryonic stem cells(ESCs) maintain their cellular identity through the systematic regulation of master transcription factors and chromatin remodeling complexes. Recent work has shown that the unusually large-scale enhancers—namely super-enhancers(SEs), on which BRD4, a member of the bromodomain and extraterminal domain(BET) family is highly enriched—could regulate pluripotency-related transcription factors. Moreover, inhibition of BRD4 binding on SEs has been shown to induce the differentiation of ESCs. However, the underlying mechanism of BRD4 inhibition-mediated stem cell differentiation remains elusive. Here we show that both mouse and human ESCs lose their capacity for self-renewal upon treatment with JQ1, a selective inhibitor of BET family including BRD4, with rapid suppression of pluripotency-associated genes. Notably, a high concentration of JQ1 could selectively eliminate ESCs via apoptosis, without affecting the functionality of differentiated somatic cells from ESCs, suggesting that inhibition of BET may have a beneficial effect on the development of pluripotent stem cell-based cell therapy. | Jung Hyun Im Seon In Hwang Jong-Wan Kim soon-Jung Park Kyu-ree Kang Jueng Soo You Kee Pyo Kim Sung-Hwan Moon Hyuk-Jin Cha Hyung-Min Chung Hans R. Scholer Jung Keun Hyun DongWook Han | 2018 | Science Bulletin2018，63，8： | 2 |
| 12 | Foldable and washable textile-based OLEDs with a multi-functional near-room-temperature encapsulation layer for smart e-textiles显示文摘Wearable electronic devices are being developed because of their wide potential applications and user convenience.Among them,wearable organic light emitting diodes(OLEDs)play an important role in visualizing the data signal processed in wearable electronics to humans.In this study,textile-based OLEDs were fabricated and their practical utility was demonstrated.The textilebased OLEDs exhibited a stable operating lifetime under ambient conditions,enough mechanical durability to endure the deformation by the movement of humans,and washability for maintaining its optoelectronic properties even in water condition such as rain,sweat,or washing.In this study,the main technology used to realize this textile-based OLED was multi-functional nearroom-temperature encapsulation.The outstanding impermeability of TiO_(2)film deposited at near-room-temperature was demonstrated.The internal residual stress in the encapsulation layer was controlled,and the device was capped by highly crosslinked hydrophobic polymer film,providing a highly impermeable,mechanically flexible,and waterproof encapsulation. | So Yeong Jeong Hye Rin Shim Yunha Na Ki Suk Kang Yongmin Jeon Seungyeop Choi Eun Gyo Jeong Yong Cheon Park Ha-Eun Cho Junwoo Lee Jeong Hyun Kwon Sung Gap Im Kyung Cheol Choi | 2021 | npj Flexible Electronics2021，5，1： | 2 |
| 13 | Finite element investigation of friction condition in a backward extrusion of aluminum alloy 显示文摘 | IM Y T KANG S H CHEON J S | 2003 | Journal of Manufacturing Science and Engineering2003，125，2： | 1 |
| 14 | Mediastinal tuberculous lymphadenitis : CT manifestations 显示文摘 | Im JG Song KS Kang HS | 1987 | Radiology1987，164，1： | 1 |
| 15 | The application of magnets directs the orientation of neurite outgrowth in cultured human neuronal cells 显示文摘 | Kim S Im WS Kang L | 2008 | J Neurosci Methods2008，174，1： | 1 |
| 16 | Mediastinal tuberculous lym- phadenitis:CT manifestations显示文摘 | Im JG Song KS Kang HS | 1987 | Radiology1987，164，1： | 1 |
| 17 | Determination of friction condition by geometrical measurement of backward extruded alu minum alloy specimen 显示文摘 | IM Y T CHEON J S KANG S H | 2002 | Journal of Manufacturing Science and Engineering2002，124，2： | 1 |
| 18 | Clinical outcomes and patency of self-expanding metal stents in patients with malignant colorectal obstruction:a prospective single center study显示文摘 | Im JP Kim SG Kang HW | | 0，，11： | 1 |
| 19 | Arabidopsis basic leucine zipper proteins mediate stress-responsive abscisic acid signaling显示文摘 | KANG J CHOI H IM M KIM S Y | 2002 | Plant Cell2002，14，2： | 1 |
| 20 | Mediastinal tuberculous lymphadenitis:CT manifestations显示文摘 | Im J G Song K S Kang H S | 1987 | Radiology1987，164，1： | 1 |
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