|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | T1ρ/T2 mapping and histopathology of degenerative cartilage in advanced knee osteoarthritis显示文摘AIM To investigate whether normal thickness cartilage in osteoarthritic knees demonstrate depletion of proteoglycan or collagen content compared to healthy knees.METHODS Magnetic resonance(MR) images were acquired from5 subjects scheduled for total knee arthroplasty(TKA)(mean age 70 years) and 20 young healthy control subjects without knee pain(mean age 28.9 years). MR images of T1ρ mapping, T2 mapping, and fat suppressed proton-density weighted sequences were obtained.Following TKA each condyle was divided into 4 parts(distal medial, posterior medial, distal lateral, posterior lateral) for cartilage analysis. Twenty specimens(bone and cartilage blocks) were examined. For each joint,the degree and extent of cartilage destruction was determined using the Osteoarthritis Research Society International cartilage histopathology assessment system.In magnetic resonance imaging(MRI) analysis, 2 readers performed cartilage segmentation for T1ρ/T2 values and cartilage thickness measurement.RESULTS Eleven areas in MRI including normal or near normal cartilage thickness were selected. The corresponding histopathological sections demonstrated mild to moderate osteoarthritis(OA). There was no significant difference in cartilage thickness in MRI between control and advanced OA samples [medial distal condyle, P = 0.461;medial posterior condyle(MPC), P = 0.352; lateral distal condyle, P = 0.654; lateral posterior condyle, P = 0.550],suggesting arthritic specimens were morphologically similar to normal or early staged degenerative cartilage.Cartilage T2 and T1ρ values from the MPC were significantly higher among the patients with advanced OA(P= 0.043). For remaining condylar samples there was no statistical difference in T2 and T1ρ values between cases and controls but there was a trend towards higher values in advanced OA patients. CONCLUSION Though cartilage is morphologically normal or near normal, degenerative changes exist in advanced OA patients. These changes can be detected with T2 and T1ρ MRI techniques. | Benjamin S Kester Philip M Carpenter Hon J Yu Taiki Nozaki Yasuhito Kaneko Hiroshi Yoshioka Ran Schwarzkopf | 2017 | World Journal of Orthopedics2017，8，4： | 12 |
| 2 | Potent inhibition of estrogen sulfotransferase by hydroxylated metabolites of polyhalogenated aromatic hydrocarbons reveals alternative mechanism for estrogenic activity of endocrine disrupters显示文摘 | Kester M H Bulduk S Van Toor H | 2002 | The Journal of Clinical Endocrinology and Metabolism2002，87，3： | 1 |
| 3 | Shock absorption charac teristics of running shoes显示文摘 | COOK S KESTER M BRUNET M | 1985 | Am J Sports Med1985，13，： | 1 |
| 4 | Quantitative determination of contact stiffness using atomic force acoustic microscopy 显示文摘 | RABE U AMELIO S KESTER E | 2000 | Ultrasonics2000，38，18： | 1 |
| 5 | The health benefits of calcium citrate malate: a review of the supporting science显示文摘 | REINWALD S WEAVER C M KESTER J J | 2008 | Adv Food Nutr Res2008，54，： | 1 |
| 6 | On the approximation of horizontal gradients in sigma coordinates for bathymetry with steep bottom slopes显示文摘 | Stelling G S Kester A M | 1994 | International Journal for Numerical Methods in Fluids1994，18，： | 1 |
| 7 | On the approximation of horizontal gradients in sigma co-ordinates for bathymetry with steep bottom slopes显示文摘 | STELLING G S van KESTER J A T M | 1994 | International Journal for Numerical Methods in Fluids1994，18，9： | 1 |
| 8 | On the approximation of horizontal gradients in sigma co-ordinates for bathymetry with steep bottom slopes 显示文摘 | Guus S Stelling Jan A Th M Van Kester | 1994 | International Hournal for Numerical Methods in Fluids1994，18，： | 1 |
| 9 | Quantitative Determination of Contact Stiffness Using Atomic Force Acoustic Microscopy 显示文摘 | RABE U AMELIO S KESTER E | 2000 | Ultrasonics2000，38，18： | 1 |
| 10 | Potent inhibition of estrogen sulfotransferase by hydroxylated PCB metabolites: a novel pathway explaining the estrogenic activity of PCBs显示文摘 | Kester M H A Bulduk S Tibboel D | 2000 | Endocrinology2000，141，5： | 1 |
| 11 | 显示文摘 | Kester D J Ailey K S Lichtenwalner D J | 1994 | J Vac Sci Technol1994，12，： | 1 |
| 12 | Mi- croRNA-21 expression in CD4+ T cells is regulated by STAT3 and is pathologically involved in Sezary syndrome显示文摘 | VAN DER FITS L VAN KESTER M S QIN Y J | 2011 | The Journal of Investigative Dermatology2011，131，3： | 1 |
| 13 | The dissolution of atmospheric iron in surface seawater of the open ocean显示文摘 | Zhuang G S Duce R A Kester D R | 1990 | Journal of Geophysical Research1990，95，16： | 1 |
| 14 | Capital Budgeting Practices in the Asia-Pacific Region: Australia, Hong Kong, Indonesia, Malaysia, Philippines, and Singapore显示文摘 | Chang R P Echanis E S | 1999 | Financial Practice in Education1999，9，1： | 1 |
| 15 | Compact Image Slicing Spec- trometer (ISS) for Hyper spectral Fluorescence Microscopy显示文摘 | Gao L Kester R T Tkaczyk T S | 2009 | Optics Express2009，17，16： | 1 |
| 16 | Isotopic study of sulfate sources and residence times in a subalpine watershed显示文摘 | Kester C L Baron J S Turk J T | 2003 | Environmental Geology2003，43，5： | 1 |
| 17 | The dissolution of atmospheric iron in surface seawater of the open ocean显示文摘 | Zhuang G S Duce R A Kester D R | 1990 | Journal of Geophysical Research1990，95，16： | 1 |
| 18 | Adapting Prior Knowledge Activation: Mobilisa- tion, Perspective Taking, and Learners Prior Knowledge显示文摘 | WETZELS S KESTER L VAN MERRIBOER J G | 2011 | Computers in Human Behavior2011，27，1： | 1 |
| 19 | On the approximation of horizontal gradients in sigma coordinates for bathymetry with steep bottom slopes显示文摘 | Stelling G S Van Kester J A | 1994 | International Journal for Numerical Methods in Fluids1994，18，： | 1 |
| 20 | Vemurafenib ( PLX- 4032) :an orally available inhibitor of mutated BRAF for the treatment of metastatic melcnoma 显示文摘 | HEAKAL Y KESTER M SAVAGE S | 2011 | Ann Pharmacother2011，45，11： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员