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| 1 | Chronic pancreatitis:A diagnostic dilemma显示文摘Typical clinical symptoms of chronic pancreatitis are vague and non-specific and therefore diagnostic tests are required, none of which provide absolute diagnostic certainly, especially in the early stages of disease. Recently-published guidelines bring much needed structure to the diagnostic work-up of patients with suspected chronic pancreatitis. In addition, novel diagnostic modalities bring promise for the future. The assessment and diagnosis of pancreatic exocrine insufficiency remains challenging and this review contests the accepted perspective that steatorrhea only occurs with > 90% destruction of the gland. | Sinead N Duggan Hazel M NíChonchubhair Oladapo Lawal Donal B O’Connor Kevin C Conlon | 2016 | World Journal of Gastroenterology2016,22,7: | 4 |
| 2 | p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival显示文摘响应 DNA 损坏的房间命运的中央仲裁人是 p53,它调整涉及房间周期拘捕,幸存和 apoptosis 的基因的表示。尽管 DNA 损坏开始的许多回答被描绘了,肌动朊细胞骨架管理者的角色大部分是未知的。我们现在显示出那 RhoC 和秘鲁利玛机场之代号 kinase (LIMK2 ) 2 是 genotoxic 代理人导致的直接 p53 目标基因。尽管 RhoC 和 LIMK2 在肌动朊细胞骨架规定有生长得很好的角色,我们的结果显示 LIMK2 的激活也有支持幸存的功能追随者 DNA 损坏。由调停 siRNA 的击倒或选择的药理学封锁的 LIMK 抑制敏化房间到无线电 -- 或化疗,以便当与 LIMK 抑制结合了时,当单身地管理了时,是尚不致命的治疗导致了房间死亡。我们的调查结果建议把 LIMK 禁止者与 genotoxic 治疗相结合能比单个代理人的管理更有效,并且加亮在肌动朊细胞骨架管理者和 DNA 之间的一个新奇连接导致损坏的房间幸存机制。 | Daniel R Croft Diane Crighton Michael S Samuel Filipe C Lourenco June Munro Jenifer Wood Karim Bensaad Karen H Vousden Owen J Sansom Kevin M Ryan Michael F Olson | 2011 | Cell Research2011,21,4: | 3 |
| 3 | Advances in cellulose ester performance and application显示文摘 | Kevin J Edgar Charles M Buchanan John S Debenham Paul A Rundquist Brian D Seiler Michael C Shelton Debra Tindall | 2001 | Progress in Polymer Science2001,,9: | 2 |
| 4 | Is there an anatomical endophenotype for neurodevelopmental disorders? A review of dual disorder anatomical likelihood estimation (ALE) meta-analyses of grey matter volumes显示文摘The term 'neurodevelopmental disorder' broadly encompasses conditions thought to arise early in development and includes schizophrenia, bipolar disorder and autism among others. These conditions share a number of genetic and environmental risk factors postulated to lead to common difficulties in socio-emotional processing, communication and cognitive function. The alternative position is that, while the same traits are affected across these conditions, the nature or direction in which they are modified may be distinct. MRI studies provide a rapidly expanding and rich database which we propose can be used to contribute to this debate. Anatomical likelihood estimation (ALE) is a method of meta-analysis applied to voxel-based MRI studies. We have adapted this method to explore the extent to which schizophrenia and bipolar disorder and schizophrenia and autism share a common brain structural phenotype. We will review this work here and discuss whether there is sufficient other evidence to justify a common framework for further research into the inter-relatedness of such conditions. | MCALONAN Grainne M YU Kevin K CHAN Raymond C K CHUA Siew E CHEUNG Charlton | 2011 | Chinese Science Bulletin2011,56,32: | 2 |
| 5 | Behavioural and neurochemical effects of post-weaning social isolation in rodents-Relevance to developmental neuropsychiatric disorders显示文摘 | Kevin C F F Veronica M P | 2008 | Neuroscience and Biobehavioral Reviews2008,,32: | 1 |
| 6 | Parsimony in landscape metrics: Strength, universality, and consistency显示文摘 | Samuel A C Kevin M Maile C N | 2008 | Ecological Indicators2008,8,5: | 1 |
| 7 | A rapid competitivebinding nonseparationelectro chemical enzyme immunoas-say(NEEIA)test strip for microcystin-LR(MCLR)de-termination 显示文摘 | Iva D Kevin M C Kennedy D G | 2006 | Biosensors and Bioelectronics2006,5,: | 1 |
| 8 | Voluntary disclosure by state-owned enterprises listed on the Stock Exchange of Hong Kong 显示文摘 | Michael J F Kevin C K Grace M L | 2002 | Journal of International Financial Management and Accounting2002,13,2: | 1 |
| 9 | Delay T olerant Mobile Networks(DTMNs):Controlled Flooding in Sparse Mobile Networks显示文摘 | Khaled A Kevin C Elizabeth M | 2005 | IFIP Networking2005,,: | 1 |
| 10 | Metabolism and disposition of bisphenol A in female rats显示文摘 | RODNEY W S SUSAN C M KEVIN W G | 2000 | Toxicol Appl Pharmacol2000,168,3: | 1 |
| 11 | Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: results of a phase 2 consortium study显示文摘 | Keith C Bible Vera J Suman Julian R Molina Robert C Smallridge William J Maples Michael E Menefee Joseph Rubin Kostandinos Sideras John C Morris Bryan McIver Jill K Burton Kevin P Webster Carolyn Bieber Anne M Traynor Patrick J Flynn Boon Cher Goh Hui Tan | 2010 | Lancet Oncology2010,,10: | 1 |
| 12 | Power system topological observability analysis including switching branches显示文摘 | Antonio Sim6es Costa Elizete M Lourengo Kevin A C | 2002 | IEEE Transactions on Power Systems2002,17,2: | 1 |
| 13 | The investment opportunity set, director ownership, and corporate policies: evidence from an emerging market 显示文摘 | Simon S M Ho Kevin C K Heibatollah Sami | 2004 | Journal of Corporate Finance2004,,10: | 1 |
| 14 | Performance pay and top management incentives显示文摘 | Jensen Michael C M urphy Kevin j | 1998 | Journal of Political Economy1998,,201: | 1 |
| 15 | The investment opportunity set,director ownership and corporate policies:evidence from an emerging market显示文摘 | Simon S M H Kevin C K L Heibatollah S | 2004 | Journal of Corporate Finance2004,10,3: | 1 |
| 16 | Transoral Incisionless Fundoplication: 2-year Results from the Prospective Multicenter U.S. Study显示文摘 | Bell Reginald C W Barnes William E Carter Bart J Sewell Robert W Mavrelis Peter G Ihde Glenn M Hoddinott Kevin M Fox Mark A Freeman Katherine D Gunsberger Tanja Hausmann Mark G Dargis David Gill Brian DaCosta Wilson Erik Trad Karim S | 2014 | The American Surgeon2014,,11: | 1 |
| 17 | Microwave remote sensing of coastal zone salinity显示文摘 | Goodberlet M A Swift C T Kevin K P | 1997 | Journal of Coastal Research1997,13,2: | 1 |
| 18 | Floc Morphology and Cyclic Shearing Recovery: Comparison of Alum and Polyaluminium Chloride Coagulants显示文摘 | Kevin M Kenneth C Dean G | 2004 | Water Res2004,38,2: | 1 |
| 19 | Phylogenetic utility of protein (RPB2,b-tubulin) and ribosomal (LSU,SSU) gene sequences in the systematic of Sordariomycetes (Ascomycota,Fungi)显示文摘 | ALVIN M C RAJESH J KEVIN D H | 2007 | Antonie Van Leeuwenhoek2007,91,: | 1 |
| 20 | A genetic linkage map including loci for male sterility, sugars, and ascorbic acid in melon显示文摘 | SOON O P HYE Y H KEVIN M C | 2009 | Journal of the American Society for Horticulture Science2009,134,1: | 1 |