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| 1 | Persistent alanine aminotransferase elevation among the general Iranian population: Prevalence and causes显示文摘AIM: To determine the prevalence and causes of persistently elevated alanine aminotransferase (ALT) levels among the general population in northern Iran. METHODS: A total of 2292 (1376 female, aged 18-75 year), were selected by systematic clustered random sampling from the cities and villages of Gonbad and Kalaleh in Golestan Province and invited to participate in the study. A comprehensive history regarding alcohol drinking and medication was taken. Body mass index (BMI), viral markers and ALT levels were measured. If ALT level was ≥ 40 U/L, it was rechecked twice within 6 mo. Those with ≥ 2 times elevation of ALT were considered as having persistently elevated ALT level. Non-alcoholic fatty liver disease (NAFLD) was diagnosed based on evidence of fatty liver upon sonography and excluding other etiology. RESULTS: A total of 2049 (1351 female) patients participated in the study, 162 (7.9%) had elevated ALT level at the first measurement. Persistently elevated ALT level was detected in 64 (3.1%) participants, with51 (79.6%) with no obvious etiology, six (9.3%) with Hepatitis B, four (6.2%) with Hepatitis C virus (HCV) infection and three (4.6%) with alcoholic hepatitis. The prevalence of NAFLD and alcoholic hepatitis was 2.04% (42 patients) and 0.1% (three), respectively. There was correlation between NAFLD and male gender, overweight, diabetes and living in an urban area [odds ratio = 3.03 (95% CI: 1.6-5.72), 4.21 (95% CI: 1.83-9.68), 2.86 (95% CI: 1.05-7.79) and 2.04 (95% CI: 1.00-4.16) respectively]. CONCLUSION: NAFLD is the most common cause of persistently elevated serum ALT level among the general population of Iran. | Raika Jamali Mahmoodreza Khonsari Shahin Merat Masoud Khoshnia Elham Jafari Alireza Bahram Kalhori Hassan Abolghasemi Sedighe Amini Mahtab Maghsoudlu Mohammad Reza Deyhim Houri Rezvan Akram Pourshams | 2008 | World Journal of Gastroenterology2008，14，18： | 7 |
| 2 | Flow characteristics of a powder lubrication sheared between parallel plates显示文摘 | Zhou L Khonsari M M | 2000 | ASME Tribol2000，122，1： | 1 |
| 3 | On the orle of particulate contamination in scuffing fatigue显示文摘 | M M Khonsari S H Wang | 1990 | Wear1990，137，： | 1 |
| 4 | Hydrodynamic analysis of com- pliant foil bearings with compressible air flow显示文摘 | Peng Z C Khonsari M M | 2004 | Transac- tions of the ASME2004，126，3： | 1 |
| 5 | Effects of oil inlet pressure and inlet position of axially grooved infinitely long journal bearings, Part II: Nonlinear instability analysis显示文摘 | WANG J K KHONSARI M M | 2008 | Tribology International2008，41，2： | 1 |
| 6 | What happens to hemostatic agents in contact with urine?An in vitro study显示文摘 | Uribe C Eichel L Khonsari S | 2005 | J Endouro12005，19，3： | 1 |
| 7 | Hydrodynamic analysis of com- pliant foil bearings with compressible air flow显示文摘 | Peng Z C Khonsari M M | 2004 | Transac- tions of the ASME2004，126，3： | 1 |
| 8 | On the limiting load-carrying ca- pacity of foil bearings显示文摘 | Peng Z C Khonsari M M | 2004 | ASME Journal of Tribology2004，126，4： | 1 |
| 9 | A thermohydrodynamic analysis of foil journal bearings显示文摘 | Peng Z C Khonsari M M | 2006 | Transactions of the ASME2006，128，3： | 1 |
| 10 | Experimental and theoret- ical investigation of running-in显示文摘 | AKBARZADEH S KHONSARI M M | 2011 | Tribology International2011，44，： | 1 |
| 11 | Application of Transient Elastohydrodynamic Lubrication Analysis for Gear Transmissions 显示文摘 | Hua D Y Khonsari M M | 1995 | STLE Tribology Transactions1995，38，4： | 1 |
| 12 | A review of thermal effects in hydrodynamic bearings,partⅡ:journal bearings显示文摘 | Khonsari M M | 1986 | ASLE Transactions1986，30，1： | 1 |
| 13 | A thermohydrodynamic analysis of foil journal bearings显示文摘 | Peng Z C Khonsari M M | 2006 | Transactions of the ASME2006，128，3： | 1 |
| 14 | A modification of the switch function in the Elrod cavitaiton algorithm 显示文摘 | Fesanghary M Khonsari M M | 2011 | Journal of Tribology2011，133，： | 1 |
| 15 | Thermoelastohydrody- namic analysis of spur gears with consideration of surface roughness显示文摘 | Akbarzadeh S Khonsari M M | 2008 | Tribology Letters2008，32，2： | 1 |
| 16 | Experimental investigation on the stick-slip phenomenon in granular collision lubrication显示文摘 | Elkholy K N Khonsari M M | 2008 | ASME Tribol2008，130，02： | 1 |
| 17 | Heat transfer correlations for laminar flows within a mechanical seal chamber显示文摘 | Luan Zhaogao Khonsari M M | 2009 | Tribology International2009，42，5： | 1 |
| 18 | Combined effect of shearthinning and viscous heating on EHL characteristics ofrolling/sliding line contacts显示文摘 | Kumar P Khonsari M M | 2008 | Journal of Tribology2008，130，4： | 1 |
| 19 | Ther- mal and dynamic characterization of wet clutch en- gagement with provision for drive torque显示文摘 | Mansouri M Holgerson M Khonsari M M | 2001 | Journal of Tribology2001，123，4： | 1 |
| 20 | Bifurcation analysis of a flexible rotor supported by two fluid-film journal bearings显示文摘 | WANG J K KHONSARI M M | 2006 | ASME Journal of Tribology2006，128，3： | 1 |
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