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| 1 | Platelet thromboxane(11-dehydro-Thromboxane B_2) and aspirin response in patients with diabetes and coronary artery disease显示文摘Aspirin(ASA) irreversibly inhibits platelet cyclooxygenase-1(COX-1) leading to decreased thromboxane-mediated platelet activation. The effect of ASA ingestion on thromboxane generation was evaluated in patients with diabetes(DM) and cardiovascular disease. Thromboxane inhibition was assessed by measuring the urinary excretion of 11-dehydro-thromboxane B2(11dhTxB2), a stable metabolite of thromboxane A2. The mean baseline urinary 11dhTxB2 of DM was 69.6% higher than healthy controls(P = 0.024): female subjects(DM and controls) had 50.9% higher baseline 11dhTxB2 than males(P = 0.0004), while age or disease duration had no influence. Daily ASA ingestion inhibited urinary 11dhTxB2 in both DM(71.7%) and controls(75.1%, P < 0.0001). Using a pre-established cut-off of 1500 pg/mg of urinary 11dhTxB2, there were twice as many ASA poor responders(ASA 'resistant') in DM than in controls(14.8% and 8.4%, respectively). The rate of ASA poor responders in two populations of acute coronary syndrome(ACS) patients was 28.6 and 28.7%, in spite of a significant(81.6%) inhibition of urinary 11dhTxB2(P < 0.0001). Both baseline 11dhTxB2 levels and rate of poor ASA responders were significantly higher in DM and ACS compared to controls. Underlying systemic oxidative inflammation may maintain platelet function in atherosclerotic cardiovascular disease irrespective of COX-1 pathway inhibition and/or increase systemic generation of thromboxane from non-platelet sources. | Luis R Lopez Kirk E Guyer Ignacio Garcia De La Torre Kelly R Pitts Eiji Matsuura Paul RJ Ames | 2014 | World Journal of Diabetes2014，5，2： | 13 |
| 2 | 迷宫密封结构对泄漏量和轴系临界转速影响分析研究显示文摘运用数值方法对转子-轴承-密封系统动力学模型求解,对3种密封间隙、8种密封直径、8种压差、8种入口损失率和21种密封长度对泄漏量和临界转速的影响进行研究;通过密封结构对轴系临界转速影响规律进行研究,对比分析了有、无密封力作用下转子-轴承-密封系统对临界转速影响。研究结果表明:通过与DYNLAB程序、TASCFlow程序的结果对比分析,该数学模型能较好的模拟计算泄漏量和转子系统临界转速;通过对泄漏量影响规律研究,得出泄漏量随着密封间隙、密封直径和密封长度做增大而增大,泄漏量随压差和入口损失率的增大而减小。通过对临界转速影响规律研究,得到考虑密封会提高临界转速,密封长度的变化对临界转速的影响最大、密封间隙的变化对临界转速影响最小。 | 马文生 陈照波 焦映厚 R G Kirk | 2013 | 振动工程学报2013，26，6： | 12 |
| 3 | 转速数对滑动轴承动力学系数影响研究显示文摘建立了滑动轴承的基于短轴承非线性油膜力模型,通过转速对轴承动力学特性的影响研究,得到了偏心率、最小油膜厚度、最大油膜压力、摩擦功耗、温升、临界轴颈质量、刚度系数、阻尼系数、二维和三维油膜压力的影响因素研究;在对三维油膜压力分析时发现转速存在一个临界值,当转速低于这个临界值时,转速对最大油膜压力影响较大,当转速高于这个临界值时,转速对最大油膜压力影响不大。 | 马文生 陈照波 焦映厚 Kirk R G | 2014 | 振动与冲击2014，33，5： | 11 |
| 4 | 偏心率和转速对迷宫密封力和动力学参数影响分析研究显示文摘通过数值方法和商用CFD(计算流体动力学)软件对密封-转子系统进行建模和求解,研究了5种偏心率和5种转速下的计算机求解时间、流场压力分布、密封力的变化情况,并对泄漏量影响分析和迷宫密封动力学参数影响进行分析研究。研究结果表明:该方法能较好地模拟计算迷宫密封泄漏量和动力学参数,得到腔室压力随着偏心率增大而增大,密封切向力随着偏心率、转速的增大而增大,密封径向力随着偏心率、转速的增大而负向增大;通过密封长度、密封间隙、密封压差对泄漏量影响计算,三者变化率分别为6.62%,65.21%和69.97%,表明密封间隙和压差变化是影响泄漏量变化的重要影响因素;通过密封压差和密封长度对动力学参数影响分析,得出增大密封压差和密封长度不利于系统稳定、增大密封间隙会使得系统趋于稳定。 | 马文生 陈照波 焦映厚 R G Kirk | 2012 | 振动工程学报2012，25，3： | 7 |
| 5 | Quality in the technical performance of colonoscopy and the continuous quality improvement process for colonoscopy: recommendations of the U.S. Multi-Society Task Force on Colorectal Cancer显示文摘 | Douglas K Rex John H Bond Sidney Winawer Theodore R Levin Randall W Burt David A Johnson Lynne M Kirk Scott Litlin David A Lieberman Jerome D Waye James Church John B Marshall Robert H Riddell | 2002 | The American Journal of Gastroenterology2002，，6： | 3 |
| 6 | Service recovery: a framework and empirical investigation显示文摘 | Janis L Miller Christopher W Craighead Kirk R Karwan | 2000 | Journal of Operations Management2000，，4： | 3 |
| 7 | Shoot and root traits in drought tolerant maize(Zea mays L.) hybrids显示文摘This study aimed to investigate the differences in shoot and root traits, and water use and water use efficiency(WUE) in drought tolerant(DT) maize(Zea mays L.) hybrids under full and deficit irrigated conditions. A two-year greenhouse study was conducted with four hybrids(one conventional hybrid, 33D53AM, two commercial DT hybrids, P1151 AM, N75H, and an experimental hybrid, Exp HB) grown under two water regimes(I_(100) and I_(50), referring to 100 and 50% of evapotranspiration requirements). Under water stress, the hybids P1151 AM, N75, and Exp HB showed more drought tolerance and had either greater shoot dry weight or less dry weight reduction than the conventional hybrid(33 D53 AM). However, these three hybrids responded to water stress using different mechanisms. Compared with the conventional hybrid, the two commercial DT hybrids(P1151 AM and N75H) had a smaller leaf area, shoot dry weight, and root system per plant. As a result, these hybrids used less water but had a higher WUE compared with the conventional hybrid. In contrast, the experimental hybrid(ExpHB) produced more shoot biomass by silking stage at both irrigation levels than all other hybrids, but it had relatively lower WUE. The hybrids demonstrated different drought response mechanisms that may require different irrigation management strategies. More investigation and validation are needed under field conditions and in different soil types. | ZHAO Jin XUE Qing-wu Kirk E Jessup HOU Xiao-bo HAO Bao-zhen Thomas H Marek XU Wen-wei Steven R Evett Susan A O'Shaughnessy David K Brauer | 2018 | Journal of Integrative Agriculture2018，17，5： | 3 |
| 8 | Myostatin regulation during skeletal muscle regeneration显示文摘 | Kirk S Oldham J Kambadur R | 2000 | Cell Physiol2000，184，3： | 2 |
| 9 | Application of CFD analysis for rotating machinery--Part I: Hydrodynamic, hydrostatic bearings and squeeze film damper 显示文摘 | GUO Zenglin Hirano T Kirk R G | 2005 | Journal of Engineering for Gas Turbines and Power (S0742 - 4795)2005，127，2： | 1 |
| 10 | Application of CFD analysis for rotating machinery-Part I : hydrodynamic, hydrostatic beatings and squeeze film damper显示文摘 | Guo Zenglin Hirano Toshio Gordon Kirk R | 2005 | Journal of Engineering for Gas Turbines and Power2005，127，2： | 1 |
| 11 | Measuring erosion rates using the meter: 20 years of data from shore plaffomls, Kaik oura Peninsula, South Island, New Zealand显示文摘 | Stephenson W J Kirk R M | 1996 | Marine Geology1996，131，： | 1 |
| 12 | The influence of eddy currents on magnetic actuator performance显示文摘 | Zmood R B Anand D K Kirk J A | 1987 | Proceedings of the IEEE1987，75，2： | 1 |
| 13 | Ultrahigh reso- lution topographic mapping of Mars with MRO HiRISE stereo ima- ges : Meter - scale slopes of candidate Phoenix landing sites 显示文摘 | Kirk R L Howington -Kraus E Rosiek M R | 2008 | Journal of Geophysical Research2008，113，3： | 1 |
| 14 | Lacrimal fossa lesions: pictorial review of CT and MRI features显示文摘 | Vaidhyanath R Kirke R Brown L | 2008 | Orbit2008，27，6： | 1 |
| 15 | Ultrahighresolution topographic mapping of Mars with MRO HiRISE stereoimages: meter-scale slopes of candidate Phoenix landing sites显示文摘 | Kirk R L Howington-Kraus E Rosiek M R | 2008 | Journal of Geophysical Research Atmospheres2008，113，3： | 1 |
| 16 | Application of CFD Analysis for Rotating Machinery--Part I : Hydrodynamic, Hydrostatic Bearings and Squeeze Film Damper 显示文摘 | Guo Zenglin Hirano Toshio Gordon Kirk R | 2005 | ASME Journal of Engineering for Gas Turbines and Power2005，127，： | 1 |
| 17 | The deformation response of sol-gel-derived zirconia thin films on 316L stainless steel substrates using a substrate test显示文摘 | KIRK P B PILLIAR R M | | 0，，16： | 1 |
| 18 | Application of CFD analysis for rotating machinery-Part Ⅰ:hydrodynamic,hydrostatic bearings and squeeze film damper显示文摘 | Guo Zenglin Hirano T Kirk R G | | 0，，02： | 1 |
| 19 | The HIV Protease Inhibitor Nelfinavir Down-Regulates RET Signaling and Induces Apoptosis in Medullary Thyroid Cancer Cells 显示文摘 | Yevgeniya K Kirk J Antony R | 2014 | Journal of Clinical Endocrinology & Metabolism2014，99，20： | 1 |
| 20 | Isolation,primary sequence determination,and disulfide bond structure of cyanovirin-N,an anti-HIV (Human Immunodeficiency Virus) protein from the cyanobacterium Nostoc ellipsosporum显示文摘 | Gustafson Raymond C | 1997 | Biochem Bioph Res Co1997，238，： | 1 |
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