|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Plant Programmed Cell Death Caused by an Autoactive Form of Prf Is Suppressed by Co-Expression of the Prf LRR Domain显示文摘在西红柿, NBARC-LRR 抵抗(R) 蛋白质 Prf 与 Pto 或分 kinase 在音乐会行动对 Pseudomonas syringae pv 决定免疫。西红柿(Pst ) 。发信号的调停 Prf 的防卫被二顺序无关的藏匿 Pst 的受动器蛋白质, AvrPto 和 AvrPtoB 的识别开始,由西红柿 Pto 或分。Prf 检测这些相互作用并且激活发信号包括与 Pst 生长的拘捕被联系的局部性的规划细胞死亡(PCD ) 导致宿主防卫回答。当短暂地在 Nicotiana benthamiana 的叶子表示了时,我们发现有在在在 NBARC 领域的 IHD 主题(isoleucine-histidine-aspartic 酸) 的 D1416 的单个氨基酸替换的 Prf 变体引起受动器无关的 PCD,建议 D1416 起在 Prf 的激活的一个重要作用。Prf (NPrf ) 和 LRR 领域的 N 终端区域为发信号的这 autoactive Prf 房间死亡被要求但是为 PrfD1416V 蛋白质的累积非必需。显著地, Prf LRR 然而并非 NPrf 的合作表示与 PrfD1416V, AvrPto/Pto, AvrPtoB/Pto, Pto (PtoY207D ) 的一种 autoactive 形式,或分完全压制 PCD。然而, Prf LRR 不防碍 PCD 由 Rpi-blb1D475V 引起了,表明事件的不同 R 调停蛋白质的 PCD,或由 MAPKKK 的 overexpression 引起了, Prf 下游地行动的蛋白质。而且,我们发现当与 Prf LRR 领域共同表示时, PrfD1416V 蛋白质是不能的在植物房间积累,多半向房间死亡解释抑制。为 PrfD1416V 的导致 LRR 的降级的机制是未知的,但是可以在 Prf 或到独立 LRR 的绑定的 intramolecular 相互作用包含干扰到为 Prf 稳定性被需要的另外的主机蛋白质。 | Xinran Du Min Miao Xinrong Ma Yongsheng Liu Joseph C. Kuhl Gregory B. Martin Fangming Xiao | 2012 | Molecular Plant2012，5，5： | 4 |
| 2 | Reconstruction of the Ice Age Glaciation in the Southern Slopes of Mt. Everest, Cho Oyu, Lhotse and Makalu (Himalaya) (Part 1)显示文摘 | Matthias Kuhle | 2006 | Journal of Mountain Science2006，3，2： | 3 |
| 3 | Reconstruction of the Ice Age Glaciation in the Southern Slopes of Mt. Everest, Cho Oyu, Lhotse and Makalu (Himalaya) (Part 2)显示文摘 | Matthias Kuhle Geographie | 2006 | Journal of Mountain Science2006，3，3： | 3 |
| 4 | The Pleistocene Glaciation in the Karakoram Mountains:Reconstruction of Past Glacier Extensions and Ice Thicknesses显示文摘 | Matthias Kuhle | 2004 | Journal of Mountain Science2004，1，1： | 2 |
| 5 | Diagnostic usefulness of segmental and linear enhancement in dynamic breast MRI显示文摘 | N. Morakkabati-Spitz C. Leutner H. Schild F. Traeber C. Kuhl | 2005 | European Radiology2005，，9： | 2 |
| 6 | Review on Dating Methods:Numerical Dating in the Quaternary Geology of High Asia显示文摘Over the past few years,OSL and TCN datings of glacial material from High Asia have come into fashion.To this day,however,these techniques do not permit safe calibration.The intensity of the cosmic ray flux is being modulated by the solar and terrestrial magnetic fields and their secular fluctuations in the past.So far,these variations cannot be converted into the respective local TCN production rates for High Asia.We have reason to believe that the ages that are being calculated despite these uncertainties are generally overestimated.This assessment is supported by conventional radiocarbon dates and above all by the glacial chronology developed independently on the basis of the Quaternary geological method.The strongly emerging evidence for a much more extensive LGM glaciation of High Asia is,however,either being ignored or rejected by many authors,solely on the basis of the above-mentioned uncalibrated datings.This self-conceit based on the 'dating fallacy',as we call it,should be avoided since it goes decidedly against the standards of the scientific method established in Quaternary geology and makes a fundamental scientific discussion impossible. | Matthias Kuhle Sabine Kuhle | 2010 | Journal of Mountain Science2010，7，2： | 2 |
| 7 | Inability of interferon and aminogunidine to alter Cryptosporidium parvum infection in mice with severe combined immunodeficiency显示文摘 | Kuhls T L Mosier D A Abrams V L | 1994 | Journal of Parasitology1994，80，3： | 2 |
| 8 | Risk factors for posterior synechiae of the iris after 23-gauge phacovitrectomy显示文摘AIM:To identify risk factors for the development of posterior synechiae of the iris(PSI) after 23-gauge phacovitrectomy.METHODS:A retrospective chart review was performed in consecutive Asian patients treated with 23-gauge phacovitrectomy with a 3-piece intraocular lens(IOL) or a single-piece 4 haptics IOL.RESULTS:A total of 263 eyes from 242 patients were included in the study. Postoperative PSI was identified in16(6.1%) eyes. In multivariate analysis, C3F8 gas tamponade, oil tamponade, and long operation time were significantly associated with PSI formation. There was no difference in the incidence of PSI between the groups using two different types of IOL(P =0.779).·CONLUSION: C3F8 gas or oil tamponade and long operation time increased the incidence of PSI after 23-gauge phacovitrectomy. The single-piece 4 haptics IOL,in lieu of a 3-piece IOL, may be inserted into the capsular bag with a comparable incidence of PSI. | Jong-Hyun Oh Jaehoon Na Seong-Woo Kim Jaeryung Oh Kuhl Huh | 2014 | International Journal of Ophthalmology(English edition)2014，7，5： | 2 |
| 9 | 骨髓动员对骨髓造血干细胞在心肌梗死后心脏中定植及分化的影响显示文摘目的观察小鼠心肌梗死后骨髓造血干细胞在心脏内的分化及细胞因子的影响。方法C57/BL6小鼠60只分为骨髓动员组和对照组,先后行脾切除、骨髓移植(骨髓供体为增强绿色荧光蛋白转基因小鼠)、骨髓动员及建立心肌梗死模型。心肌梗死后3周将小鼠心脏取出并切片行组织学及激光共聚焦显微镜免疫荧光检查。结果骨髓动员可以增加EGFP阳性细胞在心脏中梗死区和边缘区的定植,但绝大多数EGFP阳性细胞都同时表达CD45。仅发现有极少数骨髓来源的心肌细胞、成纤维细胞及血管内皮细胞,且与骨髓动员无相关性。结论骨髓动员能够明显促进骨髓来源细胞定植入小鼠心脏的梗死区;极少数骨髓造血干细胞可以分化为心肌细胞,其数量远不足以修复梗死心肌及改善心功能;骨髓造血干细胞不参与梗死区疤痕形成的病理过程。 | 田文 曾定尹 Michael Kuhl mann Sigrid Nikol | 2009 | 中国组织化学与细胞化学杂志2009，18，3： | 2 |
| 10 | The Glacial(MIS 3-2)Outlet Glacier of the Marsyandi Nadi-icestream-network with its Ngadi Khola Tributary Glacier(Manaslu-and Lamjung Himalaya):The Reconstructed Lowering of the Marsyandi Nadi Ice Stream Tongue down in to the Southern Himalaya Foreland显示文摘For the reconstruction of past climate variations,investigations on the history of glaciers are necessary.In the Himalaya,investigations like these have a rather short tradition in comparison with other mountains on earth.At the same time,this area on the southern margin of Tibet is of special interest because of the question as to the monsoon-influence that is connected with the climate-development.Anyhow,the climate of High Asia is of global importance.Here for the further and regionally intensifying answer to this question,a glacial glacier reconstruction is submitted from the CentralHimalaya,more exactly from the Manaslu-massif.Going on down-valley from the glacial-historical investigations of 1977 in the upper Marsyandi Khola(Nadi) and the partly already published results of field campaigns in the middle Marsyandi Khola and the Damodar- and Manaslu Himal in the years 1995,2000,2004 and 2007,new geomorphological and geological field- and laboratory data are introduced here from the Ngadi(Nadi) Khola and the lower Marsyandi Nadi from the inflow of the Ngadi(Nadi) Khola down to the southern mountain foreland.There has existed a connected ice-stream-network drained down to the south by a 2,100-2,200 m thick and 120 km long Marsyandi Nadi main valley glacier.At a height of the valley bottom of c.1,000 m a.s.l.the Ngadi Khola glacier joined the still c.1,300 m thick Marsyandi parent glacier from the Himalchuli-massif(Nadi(Ngadi) Chuli) – the south spur of the Manaslu Himal.From here the united glacier tongue flowed down about a further 44 km to the south up to c.400 m a.s.l.(27°57'38 'N/84°24'56' E) into the Himalaya fore-chains and thus reached one of or the lowest past ice margin position of the Himalayas.The glacial(LGP(Last glacial period),LGM(Last glacial maximum) Würm,Stage 0,MIS 3-2) climatic snowline(ELA = equilibrium line altitude) has run at 3,900 to 4,000 m a.s.l.and thus c.1,500 altitude meters below the current ELA(Stage XII) at 5,400-5,500 m a.s.l.The reconstructed,maximum lowering of the climatic snowline(ΔELA = depression of the equilibrium line altitude) about 1,500 m corresponds at a gradient of 0.6°C per 100 altitude meters to a High Glacial decrease in temperature of 9°C(0.6 × 15 = 9).At that time the Tibetan inland ice has caused a stable cold high,so that no summer monsoon can have existed there.Accordingly,during the LGP the precipitation was reduced,so that the cooling must have come to more than only 9°C. | Matthias KUHLE | 2014 | Journal of Mountain Science2014，11，1： | 2 |
| 11 | Dynamic breast MR imaging:are signal intensity time course data useful for differential diagnosis of enhancing lesions? 显示文摘 | Kuhl CK Mielcareck P Klaschik S | 1999 | Radiology1999，211，： | 1 |
| 12 | Developmental hemostasis:pro-and anticoagulant systems during childhood显示文摘 | KUHLE S MALE C MITCHELL L | 2003 | Semin Thromb Hemest2003，29，： | 1 |
| 13 | Pre-operative staging of breast cancer with breast MRI one step forward,two steps back?显示文摘 | Kuhl C Kuhn W Braun M | 2007 | Breast2007，16，2： | 1 |
| 14 | Immunohistological detection of Parvovirus B19 capsid proteins in endomyocardial biopsies from dilated cardiomyopathy patients显示文摘 | Escher F Kuhl U Sabi T | 2008 | Medl Sci Monitor2008，14，6： | 1 |
| 15 | Functional interaction of β-catenin with the transcription factor LEF-1显示文摘 | Behrens J von Kries JP Kuhl M | 1996 | Nature1996，382，6592： | 1 |
| 16 | Virtual Prototyping Simulation for Design of Mechanical Systems显示文摘 | HAUG E J CHOI K K ZZJ G Kuhl | 1995 | Transactions of the ASME Special 50th Anniversary DesignIssue1995，117，： | 1 |
| 17 | Progressive posthemorrhagic hydrocephalus leads to changes of amplitude-integrated EEG activity in preterm infants显示文摘 | Olischar M Klebermass K Kuhle S | 2004 | Childs Nerv Syst2004，20，1： | 1 |
| 18 | Back to basics:valida-tion of the admission systemic inflammatory response syndrome score inpredicting outcome in trauma显示文摘 | Malone DL Kuhls D Napolitano LM | 2001 | J Trauma2001，51，3： | 1 |
| 19 | MRI of breast tumors显示文摘 | Kuhl CK | 2000 | Eur Radiol2000，10，1： | 1 |
| 20 | Breast MRI : guidelines from the european society of breast imaging显示文摘 | Mann RM Kuhl CK Kinkel K | 2008 | Eur Radiology2008，18，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员