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| 1 | Anti-microbial principles of selected remedial plants from Southern India显示文摘Objective:To examine the anti-bacterial activity of leaf extracts of Morus alba L.(Moraceae)and Piper betel L.(Piperaceae),and seed extracts of Bombax ceiba L.(Borabacaceae).Methods:We have partially purified plant extracts by solvent extraction method,and evaluated the effect of individual fractions on bacterial growth using Escherichia coli(E.coli),Pseudomonas aeruginosa(P.aeruginosa) and Staphylococcus aureus(S.aureus) bacterial strains.Results:Compared with Morus and Bombax fractions,Piper fractions showed significant growth inhibition on all the three types of bacteria studied.The EtOAc-hexane fractions of Piper leaves exhibited significant antibacterial activity with minimum inhibitory concentrations(MIC) of 50 μg/mL culture against both gram-positive and gram-negative bacteria.The EtOAc-fractions Ⅰ,Ⅱ,and Ⅳ inhibited bacterial colony formation on soft agar in addition to growth inhibition.A combination treatment of piper fractions with ampicillin resulted in significant growth inhibition in E.coli and P.aeruginosa,and combination with anticancer drug geldanamycin(2 μg/mL) showed selective growth inhibition against P.aeruginosa and S.aureus.Three major compounds,i.e.,eugenol,3-hexene-ol and stigmasterol,were primarily identified from Piper betel leaf extractions.Among the individual compounds,eugenol treatment showed improved growth inhibition compared with stigmasterol and 3-hexene-ol.Conclusions:We are reporting potential anti-bacterial compounds from Piper betel against both gram-positive and gram-negative bacteria either alone or in combination with drug treatment. | Tirupathi Rao G Suresh Babu K J Ujwal Kumar Sujana P A Veerabhadr Raoa Sreedhar AS | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，4： | 5 |
| 2 | Central poststroke pain : a review of pathophysiology and treanrmeat 显示文摘 | Kumar B Kalita J Kumar G | 2009 | Anesth Analg2009，108，5： | 1 |
| 3 | Leader-to-formation stability 显示文摘 | Tanner H G Pappas G J Kumar V | 2004 | IEEE Transactions on Robotics and Auto- mation2004，20，3： | 1 |
| 4 | Ontogenetic development of digestive enzymes in yellowtail kingfish Seriola lalandi larvae 显示文摘 | Chen B N Qin J G Kumar M S | 2006 | Aquaculture2006，260，： | 1 |
| 5 | High diversity andwidespread occurrence of mitotic spore mats in ectomycorrhizalPezizales显示文摘 | Healy R A Smith M E Bonito G M Pfister D H Ge Z W Guevara G G ’ Williams G Stafford K Kumar L Lee T HobartC Trappe J Vilgalys R McLaughlin D J | 2013 | Molecular Ecology2013，22，： | 1 |
| 6 | Optimal probe geometry for nearinfrared spectroscopy of biological tissue显示文摘 | KUMAR G SCHMITT J M | 1997 | Applied Optics1997，36，10： | 1 |
| 7 | Low temperature wet etching to reveal sub-surface damage in sapphire substrates显示文摘 | KUMAR P LEE J LEE G | 2013 | Applied Surface Science2013，，273： | 1 |
| 8 | Central poststroke pain:a review of pathophysiology and treatment显示文摘 | Kumar B Kalia J Kumar G | 2009 | Anesth Analg2009，108，5： | 1 |
| 9 | Influence of Al Dopant on Microstructure and Optical Propertiesof ZnO Thin Films Prepared by Sol-gel Spin Coating Method显示文摘 | Srinivasan G Kumar R T R Kumar J | 2007 | Optical Materials2007，30，： | 1 |
| 10 | Evaluating manufacturers' buy-back policies in a single-period two-echelon framework under price dependent and stochastic demand显示文摘 | Arcelus F J Kumar Satyendra Srinivasan G | 2006 | Omega2006，4，： | 1 |
| 11 | Molecular evolution of a developmental pathway: phylogenetic analyses of trans- forming growth factor-beta family ligands, receptors and Smad signal transducers 显示文摘 | Newfeld S J Wisotzkey R G Kumar S | 1999 | Genetics1999，152，： | 1 |
| 12 | Increase in the enantioselectivity of asymmetric hydrogenation in water influenced by surfactants or polymerized micelles显示文摘 | KUMAR A OEHME G ROQUE J P | 1994 | Angew Chem Int Ed Eng1994，33，： | 1 |
| 13 | RSC Advance显示文摘 | Sabitha G Reddy D V Reddy S S S Yadav J S Kumar C G Sujitha P | 2012 | 2(8):72412012，2，8： | 1 |
| 14 | EphB1 receptor tyrosine kinase is expressed in bladder cancer and pro vides signals for cell survival显示文摘 | Xia G Kumar S R Stein J P | 2006 | Oncogene2006，25，5： | 1 |
| 15 | Statistical Evaluation of Lower Flammability Distance Using four Hazardous Release Models显示文摘 | Kumar A Leo J Bennett G F | 1993 | Procoss Safety Progross (AIChE)1993，12，1： | 1 |
| 16 | Evaluation of determination of 6-APA by p-dimethylaminoben- zaldehyde显示文摘 | SHEWALE J G KUMAR K K AMBEKAR G R | 1987 | Biotechnology Techniques1987，1，1： | 1 |
| 17 | Enzymatic modification of the synthetic polymer polyhydroxystyrene显示文摘 | SHAO L KUMAR G LENHART J L | 1999 | Enzyme Microb Technol1999，25，89： | 1 |
| 18 | Effect of Gd1-xdoping on magnetic, electric and dielectric proper- ties of MgGd, Fe2-xO, ferrites processed by solid state reaction technique 显示文摘 | Chand J Kumar G Kumar P | 2011 | Journal of Alloys and Compounds2011，509，40： | 1 |
| 19 | Low temperature wet etching to reveal sub-surface damage in sapphire substrates显示文摘 | KUMAR P LEE J Y LEE G W | 2013 | Applied Surface Science2013，273，2： | 1 |
| 20 | Proinflammatory cytokine levels in the serum and eerebrospinal fluid of tuberculous meningitis patients 显示文摘 | Nagesh Babu G Kumar A Kalita J | 2008 | Neurosci Lett2008，436，1： | 1 |
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