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| 1 | Investor protection and corporate governance显示文摘 | Rafael La Porta Florencio Lopez-de-Silanes Andrei Shleifer Robert Vishny | 2000 | Journal of Financial Economics2000,,1: | 16 |
| 2 | 关于在稳固的肿瘤的癌症干细胞的想法显示文摘 Cancer chemotherapy efficacy is frequently impaired by either intrinsic or acquired tumor resistance.A fundamental problem in cancer research is identifying the cell type that is capable of sustaining neoplastic growth and its origin from normal tissue cells.In recent years,the cancer stem cell(CSC) theory has changed the classical view of tumor growth and therefore the therapeutic perspective.Overcoming intrinsic and acquired resistance of cancer stem/progenitor cells to current clinical treatments represents a major challenge in treating and curing the most aggressive and metastatic cancers.On the other hand,the identification of CSCs in vivo and in vitro relies on specific surface markers that should allow the sorting cancer cells into phenotypically distinct subpopulations.In the present review,recent papers published on CSCs in solid tumors(breast,prostate,brain and melanoma) are discussed,highlighting critical points such as the choice of markers to sort CSCs and mouse models to demonstrate that CSCs are able to replicate the original tumor.A discussion of the possible role of aldehyde dehydrogenase and CXCR6 biomarkers as signaling molecules in CSCs and normal stem cells is also discussed.The author believes that efforts have to be made to investigate the functional and biological properties of putative CSCs in cancer.Developing diagnostic/prognostic tools to follow cancer development is also a challenge.In this connection it would be useful to develop a multidisciplinary approach combining mathematics,physics and biology which merges experimental approaches and theory.Biological models alone are probably unable to resolve the problem completely. | Caterina AM La Porta | 2012 | World Journal of Stem Cells2012,4,3: | 8 |
| 3 | Do Institutions Cause Growth?显示文摘 | Edward L. Glaeser Rafael La Porta Florencio Lopez-de-Silanes Andrei Shleifer | 2004 | Journal of Economic Growth2004,,3: | 4 |
| 4 | The law and economics of self-dealing显示文摘 | Simeon Djankov Rafael La Porta Florencio Lopez-de-Silanes Andrei Shleifer | 2008 | Journal of Financial Economics2008,,3: | 3 |
| 5 | Investor protection and corporate governance显示文摘 | Rafael La Porta Florencio Lopez-de-Silanes Andrei Shleifer Robert Vishny | 2000 | Journal of Financial Economics2000,,1: | 3 |
| 6 | The new comparative economics显示文摘 | Simeon Djankov Edward Glaeser Rafael La Porta Florencio Lopez-de-Silanes Andrei Shleifer | 2003 | Journal of Comparative Economics2003,,4: | 2 |
| 7 | The law and economics of self-dealing显示文摘 | Simeon Djankov Rafael La Porta Florencio Lopez-de-Silanes Andrei Shleifer | 2008 | Journal of Financial Economics2008,,3: | 2 |
| 8 | Severe cyclophosphamide-related hyponatremia in a patient with acute glomerulonephritis显示文摘Cyclophosphamide is frequently used to treat cancer,autoimmune and renal diseases,such as rapidly progressive glomerulonephritis.Its side effects are well-known,including bone marrow depression,infections,alopecia,sterility,bladder malignancy and hemorrhagic cystitis.Moreover,in some cases cyclophosphamide use has been related to the onset of hyponatremia,by development of a syndrome of inappropriate antidiuresis.Indeed,severe hyponatremia has been previously reported in patients treated with high-dose or moderate-dose of intravenous cyclophosphamide,while only few cases have been reported in patients treated with low dose.Here,we discuss a case of a syndrome of inappropriate antidiuresis followed to a single low-dose of intravenous cyclophosphamide in a patient with a histological diagnosis of acute glomerulonephritis,presenting as acute kidney injury.After cyclophosphamide administration(500 mg IV),while renal function gradually improved,the patient developed confusion and headache.Laboratory examinations showed serum sodium concentration dropped to 122 mmol per liter associated with an elevated urinary osmolality of 199 mO sm/kg,while common causes of acute hyponatremia were excluded.He was successfully treated with water restriction and hypertonic saline solution infusion with the resolution of the electrolyte disorder.This case,together with the previous ones already reported,highlights that electrolyte profile should be strictly monitored in patients undergoing cyclophosphamide therapy in order to early recognize the potentially lifethreatening complications of acute water retention. | Pasquale Esposito Maria Valentina Domenech Nicoletta Serpieri Marta Calatroni Ilaria Massa Alessandro Avella Edoardo La Porta Luca Estienne Elena Caramella Teresa Rampino | 2017 | World Journal of Nephrology2017,6,4: | 2 |
| 9 | 法律起源的经济后果(上)显示文摘过去10年里,经济学家发表的大量研究表明,一国法律的历史起源与它的法规、规范在多个方面高度关联,同时亦与其经济结果密切相关。本文总结了此领域的研究成果并试图给出一个统一的解析。对于'法律起源是重要的'这一经验性结论的反对意见,我们也给予了评述。最后,我们对本研究在经济改革中的应用进行了评估。 | Rafael La Porta Florencio Lopez-de-Silanes Andrei Shleifer 刘佳 | 2010 | 管理世界2010,26,7: | 2 |
| 10 | Govern- ment Ownership of Banks 显示文摘 | La Porta R Lopez - de - Silanes F Shleifer A | 2002 | Journal of Finance2002,57,1: | 1 |
| 11 | Trust in large organization 显示文摘 | LA PORTA R LOPEZ-DE-SILANES F SHLEIFER A | 1997 | American Economic Review1997,87,2: | 1 |
| 12 | Corporate Ownership Around the World显示文摘 | La Porta tL Lopez--de--Silanes E Shleifer A | 1999 | Journal of Finance1999,54,2: | 1 |
| 13 | Law andfinance显示文摘 | La Porta Lopez-De-Silanes Shleifer and Vishny | 1998 | Journal of Political Economy1998,106,: | 1 |
| 14 | Investor Protection and Corporate Governance 显示文摘 | La Porta R Lopez - de - Silanes F Shleifer A Vishny R | 2000 | Journal of Financial Economics2000,58,: | 1 |
| 15 | Law and Finance 显示文摘 | La Porta R Lopez-de-Silanes F Shleifer A R W Vishny | 1998 | Journal of Political Economy1998,,106: | 1 |
| 16 | The new comparative economics显示文摘 | Djankov E Glaeser E L Rafacl La Porta A | 2003 | Journal of Comparative Economics2003,,12: | 1 |
| 17 | Law and finance显示文摘 | La Porta R Lopez-de-Silanes F Shleifer A Vishny R W | 1998 | Journal of Political Economy1998,106,6: | 1 |
| 18 | Tunnel- ing显示文摘 | Johnson S La Porta R Lopez-de-Silanes F | 2000 | American Economic Review2000,90,2: | 1 |
| 19 | Tunneling显示文摘 | JOHNSON S LA PORTA R LLOPEZ-DE-SILANES Fetal | 2000 | American Economic Review2000,90,2: | 1 |
| 20 | Investor protection and corporate valuation显示文摘 | La Porta R Lopez-De-Silanes F Shleifer A | 2002 | Journal of Finance2002,57,3: | 1 |