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| 1 | Leukemia:研究鉴定出与34种AML白血病亚群相关联的基因突变显示文摘针对成年急性髓细胞白血病(acute myeloid leukemia,AML)患者的一项新的大型研究将80种癌症相关基因突变与5种AML亚型相关联。这5种AML亚型可通过特异性的染色体异常加以确定。在未来,这些发现可能有助指导基因突变测试和治疗决策。 | A-K Eisfeld K Mrózek J Kohlschmidt D Nicolet S Orwick C J Walker K W Kroll J S Blachly A J Carroll J E Kolitz B L Powell E S Wang R M Stone A de la Chapelle J C Byrd C D Bloomfield | 2017 | 现代生物医学进展2017，17，15： | 7 |
| 2 | 妊娠期高血压免疫因子、肿瘤坏死因子α、血管紧张素Ⅱ1型受体自身抗体对妊娠可溶性fms样酪氨酸1和可溶性Endoglin产物的影响显示文摘最近研究发现先兆子痫中血管新生因子、可溶性fms样酪氨酸激酶(sFlt-1)和可溶性Endoglin(sEn-doglin)不平衡;然而尚不清楚它们过度分泌的启动机制。方法:长期给予怀孕大鼠肿瘤坏死因子α(tumor necrosis factor-α,TNF-α)或抗血管紧张素Ⅱ受体的自身抗体(AT1-AA),测定其循环和胎盘的sFlt-1和(或)sEndoglin以确定这些因素的免疫调节作用。 | Parrish MR Murphy SR Rutland S Wallace K Wenzel K Wallukat G Keiser S Ray LF Dechend R Martin JN Granger JP La Marca B 黄晓斌 | 2010 | 中华高血压杂志2010，18，12： | 5 |
| 3 | Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure显示文摘 | Bristow MR Saxon LA Boehmer J | | New England Journal of Medicine0，，： | 3 |
| 4 | 前蛋白转化酶枯草溶菌素9变异、低密度脂蛋白胆固醇与神经认知功能损害的关系显示文摘尽管之前的研究引发了对抑制前蛋白转化酶枯草溶菌素9(proprotein convertase subtilisin/kexintype9,PCSK9)造成神经认知功能损害事件的关注,但近期一个第3期随机试验并没有发现药物性PCSK9抑制与神经认知损害有关。 | 黄洁 叶鹏 Mefford MT Rosenson RS Cushman M Farkouh ME McClure LA Wadley VG Irvin MR Bittner VA Safford MM Somaratne R Monda KL Muntner P Levitan EB | 2017 | 中华高血压杂志2017，25，12： | 2 |
| 5 | Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart Failure显示文摘 | Bristow MR Saxon LA Boehmer J | 2004 | N Engl J Med2004，350，21： | 1 |
| 6 | Cardiacresynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure显示文摘 | BRISTOW MR SAXON LA BOEHMER J | 2004 | N Engl J Med2004，350，21： | 1 |
| 7 | Cytokine involvement in the regulation of sleep显示文摘 | Opp MR Kapas L Toth LA | 1992 | Proc Soc Exp Biol Med1992，201，1： | 1 |
| 8 | The most effective Gold nanorod size for plasmonic photothermal therapy: theory and in vitro experiments显示文摘 | Mackey MA Ali MR Austin LA | 2014 | J Phys Chem B2014，118，： | 1 |
| 9 | Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure 显示文摘 | Bristow MR Saxon LA Boehmer J | 2004 | N Engl J Med2004，350，： | 1 |
| 10 | Autoantibodies to complement compomnents显示文摘 | Trouw LA Roos A Daha MR | 2001 | Mol Immunol2001，38，23： | 1 |
| 11 | Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure,for the comparison of medical therapy,pacing,and defibrillation in heart failure(COMPANION)investigators显示文摘 | Bristow MR Saxon LA Boehmer J | 2004 | N Engl J Med2004，350，： | 1 |
| 12 | Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure显示文摘 | Bristow MR Saxon LA Boehmer J | 2004 | N Engl J Meal2004，350，21： | 1 |
| 13 | Ectopic posterior pituitary lobe and perivertricular heterotopia: cerebral malformation with the same underlying mechanism? 显示文摘 | Mitchell LA Thamas PQ Zacharim MR | 2002 | AJNR2002，23，9： | 1 |
| 14 | Diagnostic laparoscopy in infertile women with normal hysterosalpingograms显示文摘 | BADAWI LA FLUKER MR BEBBINGTON MW | 1999 | J Reprod Med1999，44，： | 1 |
| 15 | Evaluation of platelet function by flow cytometry显示文摘 | Michelson AD Barnard MR Krueger LA | 2000 | Methods2000，21，： | 1 |
| 16 | Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure显示文摘 | Bristow MR Saxon LA Boehmer J | 2004 | N EngI J Med2004，350，21： | 1 |
| 17 | A mutation in the KCNE3 potassium channel gene is associated with susceptibility to thyrotoxic hypokalemic periodic paralysis显示文摘 | DIAS DA SILVA MR CERUTTI JM ARNALDI LA | | 0，，11： | 1 |
| 18 | Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin:studies in baboons,human coronary intervention,and human acute myocardial infarction显示文摘 | BARNARD MR KRUEGER LA | 2001 | Circulation2001，104，： | 1 |
| 19 | Circulating monocyte-platelet aggregates are an early marker of acute myocardial infarction显示文摘 | BARNARD MR KRUEGER LA | 2001 | J Am Coll Cardiol2001，38，： | 1 |
| 20 | The Natriuretic peptid family显示文摘 | Wikins MR Redondo J Brown LA | 1997 | lancet1997，349，： | 1 |
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