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    题名 作者 年代 出处 被引量
1Pentoxifylline 通过 TNF- 合成和 TGF-1 基因表示的下面规定改进肝新生显示文摘 AIM:To investigate the mechanism of pentoxifylline(PTX)improvement in liver regeneration.RESULTS:Rats were randomized into 4 groups:Control rats;Sham-sham-operation rats;Saline-70% hepatectomy plus saline solution;PTX-70%hepatectomy plus PTX.At 2 and 6 h after hepatectomy,aspartate aminotransferase,alanine aminotransferase,tumor necrosis factor(TNF)-α and interleukin-6(IL-6)serum and hepatic tissue levels were determined.Tumor growth factor(TGF)-β1 gene expression in liver tissue was evaluated 24 h after hepatectomy by quantitative reverse transcriptase polymerase chain reaction analysis.Proliferation was analyzed by mitotic index and proliferating cell nuclear antigen(PCNA)staining 48 h after hepatectomy.RESULTS:TNF-α and IL-6 serum levels increased at 2 and 6 h after hepatectomy.At 2 h after hepatectomy serum PTX was reduced but not hepatic levels of TNF-α and IL-6.A decrease in liver TGF-β1 gene expression and an increase in mitotic index and PCNA after hepatectomy were observed in the PTX treatment group in comparison to the saline group.CONCLUSION:PTX improves liver regeneration by a mechanism related to down regulation of TNF-α production and TGF-β1 gene expression.Rodrigo Bronze Martino Ana Maria Mendona Coelho Márcia Saldanha Kubrusly Regina Leito Sandra Nassa Sampietre Marcel Cerqueira Cesar Machado Telesforo Bacchella Luiz Augusto Carneiro D’Albuquerque 2012World Journal of Gastrointestinal Surgery2012,4,6:2
2Probabilistic load flow by a multi-linear simulation algorithm显示文摘LEITE D A SILVA A M ARIENTI V L 1990IEE Proc on Generation Transmission and Distribution1990,137,4:1
3Brown pigment of the nanopowder spinel ferrite prepared by combustion reaction显示文摘COSTA A C F M LEITE A M D FERREIRA H S 0,,:1
4Homogeneous three-cell networks显示文摘LEITE M D C A GOLUBITSKY M 2006Nonlinearity2006,19,:1
5Synthesis of aryl-hydrazones via ultrasound irradiation in queous medium 显示文摘LEITE A C L MORWIRA D R M COELHO L C D 2008Tetrahedron Letters2008,49,:1
6Prevalence and risk factors associated with wheezing in the first year of life 显示文摘Bessa OA Leite A J Sole D 2014J Pediatr (Rio J)2014,90,2:1
7Probabilistic wind farms generation model for reliability studies applied to brazilian sites显示文摘Leite A P Borges C L T Falcao D M 2006IEEE Trans on Power Systems2006,21,4:1
8Preparation and characterization of ethanol-treated silk fibroin dense membranes for biomaterials application using waste silk fibers as raw material显示文摘NOGUEIRA G M RODAS A C D LEITE C A P 2010Bio-Resource Technology2010,101,21:1
9Supercapacitor electrodes obtained by directly bonding 2D MoS2 on reduced graphene oxide显示文摘Firmiano E G D S Rabelo A C Leite E R 2014Adv Energy Mater2014,4,13:1
10Anti-inflammatory properties of extracts,fractions and lignans iso- lated from Phyllanthus arrtarus 显示文摘KASSUYA C A L LEITE D F P LUCILIA V D M 2005Planta Medica2005,71,8:1
11显示文摘 Leito A Ferreira L 1998Sep Purif Technol1998,13,:1
12Effect of Cobalt(II) Oxide and Manganese(IV) Oxide on Sintering of Tin(IV) Oxde 显示文摘Cerri J A Leite E R Gouvea D 1996Journal of the American Ceramic Society1996,79,3:1
13Biologicalactivities of sulfated polysaccharides from tropical seaweeds显示文摘Costa L S Fidelis G P Cordeiro S L R M Oliveira D A Sabry R B G CSmara L T D B Nobre MSS PCosta J Almeida-Lima E H C Farias E L Leite H A 0 Rocha 2010Biomedicine & Pharmacotherapy2010,64,1:1
14Structural model proposition and thermodynamic and vibrational analysis of hydrotalcite-like compounds by dft calculations显示文摘COSTA D G ROCHA A B DINIZ R SOUZA W F CHIARO S S X LEIT?O A A 0,,33:1
15Structure and Mechanical Properties of Polyamide 6/Brazilian Clay Nanocomposites显示文摘LEITE A M D ARAUJO E M da PAZ RA 2009Mat Res-Ibero-Am J Mat2009,12,2:1
16Synthesis, doc- king and in vitro activity of thiosemicarbazones, aminoacyl- thiosemi-carbazides and acyl-thiazolidones against Trypano- soma cruzi显示文摘Leite A C de Lima R S Moreira D R 2006Bioorg Med Chem Lett2006,14,11:1
17显示文摘Cerri J A Leite E R Gouvea D 1996J Am Ceram Soc1996,79,:1
18Oxidation of chalcopyrite by Acidithiobacillus ferrooxidans and Acidithiobacillus thiooxidans in shake flasks显示文摘BEVILAQUA D LEITE A L L C GARCIA O TUOVINEN O H 2002Process Biochemistry2002,38,4:1
19The cytotoxic effect and the multidrug resistance reversing action of lignans from Phyllanthus amarus显示文摘LEITE D F KASSUYA C A MAZZUCO T L 2006Planta Med2006,72,:1
20Preparation and characterization of ethanol-treated silk fibroin dense membranes for biomaterials application using waste silk fibers as raw material显示文摘Grinia M N Andrea C D Rodas CARLOS A P Leite 2010Bioresource Technology2010,101,21:1
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