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| 1 | Waist Circumference Reference Values for Screening Cardiovascular Risk Factors in Chinese Children and Adolescents显示文摘Objectives To explore the optimal threshold values of waist circumference(WC)for detecting cardiovascular(CV)risk factors among Chinese children and adolescents.Methods Association of WC with CV risk factors was studied among 65 898 children aged 7-18 years whose data were pooled from nine previous studies in China.CV risk factors in this study included hypertension(blood pressure above 95 percentile levels),dyslipidemia(with one or more of the following three indexes:TG≥1.7 mmol/L,TC≥5.18 mmol/L,and HDL-C≤1.04 mmol/L)and elevated glucose level(fasting plasma glucose ≥5.6 mmol/L).Receive-operating characteristic analysis(ROC)and logistic regression were employed to derive optimal age-and sex-specific waist circumference references for predicting CV risk factors.Results A slight increasing trend of CV risk factors was observed starting from the 75th percentile of waist circumference in the study population,while a remarkable increasing trend occurred from the 90th percentile.The optimal waist circumference thresholds for predicting high blood pressures were at the 75th percentile for both boys and girls,which was at the 90th percentiles for detecting at least two of the above three CV risk factors.In comparison with children with waist circumference below the 75th percentile,the odds ratio of two CV risk factors doubled among children with waist circumference between the 75th and the 90th percentile,and increased by 6 times among children with waist circumference above the 90th percentile.The trend of high blood pressure increasing with waist circumference remained significant after having been stratified by BMI category.Conclusion The 75th and the 90th percentiles of WC are the optimal cut-off points for predicting an increased and a substantially increased risk of CV factors in Chinese children and adolescents,respectively. | GUAN-SHENG MA CHENG-YE JI JUN MA JIE MI R1TA YT SLING FENG XIONG WEI-LI YAN XIAO-QI HU YAN-PING LI SONG-M1NG DU HONG-YUN FANG AND J1NG-XIONG JIANG | 2010 | Biomedical and Environmental Sciences2010，23，1： | 25 |
| 2 | 体内腺相关病毒-常间回文重复序列丛集及其相关蛋白9介导的基因编辑可改善家族性高胆固醇血症的动脉粥样硬化显示文摘低密度脂蛋白受体(low-density lipoprotein receptor,Ldlr)基因突变是家族性高胆固醇血症的主要原因之一,可导致动脉粥样硬化,并具有很高的终生心血管病风险。常间回文重复序列丛集(clustered regularly interspaced short palindromic repeats,CRISPR)/CRISPR相关蛋白9(CRISPR-related protein 9,Cas9)系统是基因编辑纠正基因突变从而改善疾病的有效工具。该研究的目的是通过腺相关病毒(adeno-associated virus,AAV)携带的CRISPR/Cas9系统进行体内体细胞基因编辑,以确定其能否在小鼠模型中治疗由Ldlr突变体引起的家族性高胆固醇血症。 | 刘青(译) 叶鹏(审校) Zhao H Li Y He L Pu W Yu W Li Y Wu YT Xu C Wei Y Ding Q Song BL Huang H Zhou B | 2020 | 中华高血压杂志2020，28，3： | 22 |
| 3 | Internal Oxidation of Cu-Al Alloy显示文摘 | Wu, JJ Zhang, Y Shen, YT Li, GB Lei, TQ | 1999 | Journal of Materials Science & Technology1999，15，5： | 5 |
| 4 | Hepatic adenylate energy charge levels in patients with hepatoma after hepatic artery embolization显示文摘HepaticadenylateenergychargelevelsinpatientswithhepatomaafterhepaticarteryembolizationLILi1,YANLuNan1,CHENXiaoLi1,LUWuShe... | Li, L Yan, LN Chen, XL Lu, WS Xie, XD Wu, YT | 1998 | World Journal of Gastroenterology1998，4，2： | 2 |
| 5 | High-Dose Misoprostol as an Alternative Therapy after Failed Medical Abortion显示文摘 | Li YT GQ Hou TH Chen | 2008 | Taiwan J Obstet Gynecol2008，47，4： | 1 |
| 6 | LKBI/AMPK/mTOR signaling pathway in non - small - cell lung cancer 显示文摘 | Han D Li SJ Zhu YT | 2013 | Asian Pac J Canc- er Prey2013，14，7： | 1 |
| 7 | Recent progress in pharmacokinetic applications of capillary electrophoresis 显示文摘 | Lin CC Li YT Chen SH | 2003 | Electrophoresis2003，24，： | 1 |
| 8 | Diagnosis of gastric intestinal metaplasia with confocal laser endomicroscopy in vivo: a prospective study显示文摘 | Guo YT Li YQ Yu T | 2008 | Endoscopy2008，40，7： | 1 |
| 9 | Optimization of initial substrate and pH levels for germination of sporing hydrogen-producing anaerobes in cow dung compost显示文摘 | Fan YT Li CL Lay JJ | 2004 | Bioresource Technology2004，，91： | 1 |
| 10 | Relationshipbetween the interval before high-dose methylprednisolone administration and chronic pain in traumatic spinal cord injury显示文摘 | Wu YT Li TY Chu HY | | 0，，： | 1 |
| 11 | Exercise training attenuates neuro- pathie pain and cytokine expression after chronic constriction injury of rat sciatic nerve显示文摘 | Chen YW Li YT Chen YC | 2012 | Anesth Analg2012，114，6： | 1 |
| 12 | Synergistic roles of platelet-derived growth factor-BB and interleukin-1 beta in phenotypic modulation of human aortic smooth muscle cells显示文摘 | Chen CN Li YS Yeh YT | 2006 | Proc Natl Acad Sci2006，103，8： | 1 |
| 13 | Risk factors for acute hepati- tis B and its progression to chronic hepatitis in Shanghai显示文摘 | Zhang HW Yin JH Li YT etal | 2008 | Gut2008，57，12： | 1 |
| 14 | Amelioration of collagen- in- duced arthritis in mice by lentivirus - mediated silencing of microR- NA - 223 显示文摘 | Li YT Chen SY Wang CR | 2012 | Arthritis Rheum2012，10，： | 1 |
| 15 | Optimization for quantitative determination of four flavonoids in Epimedium by capillary zone electrophoresis coupled with diode array detection using central composite design显示文摘 | Liu JJ Li SP Wang YT | 2006 | Journal of Chromatography A2006，1103，2： | 1 |
| 16 | Neurotoxicity induces cleavage of p35 to p25 by calpain显示文摘 | Lee MS Kwon YT Li M | 2000 | Nature2000，405，6784： | 1 |
| 17 | Role of B-cell-activating fac- tor in adhesion and growth of human multiple myeloma cells in the bone marrow mieroenvironment 显示文摘 | Tai YT Li XF Breitkreutz I | 2006 | Cancer Res2006，66，13： | 1 |
| 18 | Neurotoxicity induces cleavage of p35 to p25 by calpain显示文摘 | Lee MS Kwon YT Li MW | 2000 | Nature2000，405，18： | 1 |
| 19 | Expression of laminins and their integrin receptors in different conditions of synovial membrane and synovial membrane-like interface tissue显示文摘 | Konttinen YT Li TF Xu JW | | 0，，11： | 1 |
| 20 | Antibiotic therapy did not prevent the rupture of mycotic aneurysm of the superior mesenteric artery显示文摘 | Li YT Liu XB Wang T | 2015 | Heart Surg Forum2015，18，3： | 1 |
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