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| 1 | Failure of hepatocyte marker-expressing hematopoietic progenitor cells to efficiently convert into hepatocytes in vitro显示文摘 | Lian G Wang C Teng C Zhang C Du L Zhong Q Miao C Ding M Deng H | 2006 | 中国生物学文摘2006，20，5： | 11 |
| 2 | Regulation of blood-testis barrier dynamics by the mT0RCl/rpS6 signaling complex:an in vitro study显示文摘During spermatogenesis, developi ng germ cells that lack the cellular ultrastructures of filopodia and lamellipodia gen erally found in migrating cells, such as macrophages and fibroblasts, rely on Sertoli cells to support their transport across the seminiferous epithelium. These in elude the transport of preleptote ne spermatocytes across the blood-testis barrier (BTB), but also the transport of germ cells, in particular developing haploid spermatids, across the seminiferous epithelium, that is to and away from the tubule lumen, depending on the stages of the epithelial cycle. On the other hand, cell junctions at the Sertoli cell-cell and Sertoli-germ cell in terface also un dergo rapid remodeli ng, invo Iving disassembly and reassembly of cell j un ctions, which, in turn, are supported by actin- and microtubule-based cytoskeletal remodeling. Interestingly, the underlying mechanism(s) and the invoIving biomolecule(s) that regulate or support cytoskeletal remodeling remain largely unknown. Herein, we used an in vitro model of primary Sertoli cell cultures that mimicked the Sertoli BTB in vivo overexpressed with the ribosomal protei n S6 (rpS6, the down stream signali ng protein of mammalian target of rapamycin complex 1 [mTORCl]) cloned into the mammalian expression vector pCI-neo, namely, quadruple phosphomimetic and constitutively active mutant of rpS6 (pCI-neo/p-rpS6-MT) versus pCI-neo/rpS6-WT (wild-type) and empty vector (pCI-neo/Ctrl) for studies. These findings provide compelling evidence that the mT0RCl/rpS6 signal pathway exerted its effects to promote Sertoli cell BTB remodeling. This was mediated through changes in the organization of actin- and microtubulebased cytoskeletons, involving changes in the distribution and/or spatial expression of actin- and microtubule-regulatory proteins. | Lin-Xi Li Si-Wen Wu Ming Yan Qing-Quan Lian Ren-Shan Ge C Yan Cheng | 2019 | Asian Journal of Andrology2019，21，4： | 4 |
| 3 | Effect of light emitting diodes on morphogenesis and growth of bulblets of Lilium in vitro显示文摘 | Lian M L Piao X C Paek K Y | 2003 | Scientia Horticulturae2003，44，1： | 1 |
| 4 | A Theoretical-study of the liquid bridge forces between 2 rigid spherical bodies 显示文摘 | Lian GP Thornton C Adams MJ | 1993 | J Colloid Interface Sci1993，161，1： | 1 |
| 5 | A study of orthonormal multiwavelets显示文摘 | CHUI C K LIAN J A | 1996 | Appl Numer Math1996，20，2： | 1 |
| 6 | Analysis and architecture design of block-coding engine for EBCOT in JPEG2000显示文摘 | C J Lian K F Chen H H Chen | 2003 | IEEE Transactions on Circuits and System for Video Technology2003，13，3： | 1 |
| 7 | Monitoring the genetic diversity of three Asian arowana (Scleropages formosus) captive stocks using AFLP and microsatellites 显示文摘 | YUE G H YANG L LIAN C L | 2004 | Aquaculture2004，237，： | 1 |
| 8 | Discrete particle simulation ofagglomerate impact coalescence 显示文摘 | Lian G Thomtont C Adams M J | 1998 | Chemical Engineering Science(S0009-2509)1998，53，19： | 1 |
| 9 | L'alcoolisme, cause d'hypertension arterielle 显示文摘 | Lian C | 1915 | BullAcad Natl Med (Paris)1915，74，： | 1 |
| 10 | Enhanced electron screening in D(d, p)T for deuterated metals 显示文摘 | RAIOLA F LIAN G BONOMO C | 2004 | Eur Phys J A2004，19，： | 1 |
| 11 | Construction of compactly stipported symmetric and antisymmet-ric orthonormal wavelets x~'ith scale -- 3显示文摘 | Chui C K Lian Jian-ao | 1995 | Appl Comput Harmonic Anal1995，，2： | 1 |
| 12 | Biofuels and implications for agricultural water use:blue impacts of green energy显示文摘 | Giordano M Lian Y | 2008 | Water Policy2008，10，1： | 1 |
| 13 | High corrosion-resistance nanocrystalline Ni coating on AZ91D magnesium alloy显示文摘 | LIAN J S HE J G | 2006 | Surf Coat Technol2006，200，1819： | 1 |
| 14 | Simulation of ring rolling using a rigid-plastic finite element model显示文摘 | XU S G LIAN J C HAWKYARD J B | 1991 | International Journal of Mechanical Sciences1991，33，5： | 1 |
| 15 | A study of orthonormal multi-wavelets显示文摘 | Chui C K Lian J A | 1996 | J Appl Numer Math1996，20，1： | 1 |
| 16 | Effect of floodinduced chemical load on filtrate quality at bank filtration sites显示文摘 | Ray C Soong T W Lian Y Q | 2002 | Journal of Hydrology2002，，266： | 1 |
| 17 | Analysis of microstructure of hardened cement paste by finite element method 显示文摘 | Xiao C Z Lian H Z Liu X L | 1994 | Cement and Concrete Research1994，24，： | 1 |
| 18 | Mineralocorticoid receptor blockade reverses obesity-related changes in expression of adiponectin, peroxisome proliferator-activated receptor-y, and proinflammatory adipokines 显示文摘 | Guo C Riechiuti V Lian BQ | 2008 | Circulation2008，117，17： | 1 |
| 19 | Neutral lipids and peroxisome pro- liferator-activated reeeptor-γ control pulmonary gene expression and inflammation triggered pathogenesis in lysosomal acid lipase knockout mice 显示文摘 | Lian X Yah C Qin Y et ol | 2005 | Am J Pathol2005，167，3： | 1 |
| 20 | Development of microsatel-lite markers from an ectomycorrhizal fungus,Tricholoma matsutake, byan ISSRsuppression - PCR method 显示文摘 | Lian C Hogetsu T Matsushita N | 2003 | Mycorrhiza2003，，13： | 1 |
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