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    题名 作者 年代 出处 被引量
12019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W 2020中华高血压杂志2020,28,3:516
2Treatment for cartilage injuries of the knee with a new treatment algorithm显示文摘Treatment of articular cartilage injuries to the knee remains a considerable challenge today. Current procedures succeed in providing relief of symptoms, however damaged articular tissue is not replaced with new tissue of the same biomechanical properties and long-term durability as normal hyaline cartilage. Despite many arthroscopic procedures that often manage to achieve these goals, results are far from perfect and there is no agreement on which of these procedures are appropriate, particularly when full-thickness chondral defects are considered.Therefore, the search for biological solution in long-term functional healing and increasing the quality of wounded cartilage has been continuing. For achieving this goal and apply in wide defects, scaffolds are developed.The rationale of using a scaffold is to create an environment with biodegradable polymers for the in vitro growth of living cells and their subsequent implantation into the lesion area. Previously a few numbers of surgical treatment algorithm was described in reports, however none of them contained one-step or two –steps scaffolds. The ultimate aim of this article was to review various arthroscopic treatment options for different stage lesions and develop a new treatment algorithm which included the scaffolds.Ahmet ?zmeri? Kadir Bahad?r Alemdaro?lu Nevres Hürriyet Aydo?an 2014World Journal of Orthopedics2014,5,5:3
3Variations in Wool Growth with Nutrient Supply in Northern China显示文摘Field studies on essessment of nutritional status of the grazing sheep were carried out in each of the three major grassland regions, the eastern Inner Mongolia and beyond grassland, the Inner Mongolia - Ningxia - Gansu grassland and the Xinjiang grassland, in northern China. The results obtained showed that the wool production of fine wool sheep in these regions varied between regions and seasons, with similar seasonal patterns in all regions and that reducing the seasonal variations in nutrient supply would enhance wool production substantially. Nutritional limitations to wool growth of the grazing sheep in these regions were suggested, those were: the shortage of protein supply in winter and early spring; the poor quality of much of the pasture and the hay used as supplements, the low energy intake during winter which probably necessitated the use of body stores to maintain body temperature.D X Lu,Iner(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)Z C Feng,(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)H R Wang,(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)R Z Yang,(Xinjiang Institute of Animal Science.Xinjiang Academy of Animal Science.Yiu Hou Road.Urumqi.Xinjiang Uygur Autonomous Region PRC)C T Ma,(Chinese Academy of Agricultural Sciences.Lanzhou.Gansu.PRC)D B Purser,(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014)J R Lindsay(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014)D W Peter(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014) 1997畜牧与饲料科学1997,22,S1:3
4TSC1-mTOR-PLK轴以阶段特异性方式调节从施旺细胞增殖到髓鞘形成的内稳态开关显示文摘恰如其分的外周髓鞘形成取决于雪旺细胞增殖与分化进程间的平衡。丝氨酸/苏氨酸激酶(mTOR)整合多种环境因素,是细胞生长、代谢、发挥作用的中枢调节者。本文报道了一种mTOR的负性调节剂——结节性硬化复合体(TSC1),通过控制细胞增殖和髓鞘稳态,建立了雪旺细胞谱系进展和髓鞘形成的阶段依赖性程序。小鼠雪旺细胞祖细胞中TSC1的解离导致mTOR信号通路激活,继而导致雪旺细胞过量增殖,分化受阻,髓鞘形成减少。转录组分析显示,TSC1突变体中的mTOR活化使得polo样激酶(PLK)依赖性通路和细胞周期调节剂上调。弱化mTOR或者对PLK进行药理抑制部分挽救了因TSC1缺失导致的外周神经发育过程中的髓鞘形成减少。相较之下,成年小鼠成熟雪旺细胞中TSC1缺失可导致髓鞘的过度增殖和过度生长。本文的发现提示了TSC1-mTOR-PLK信号轴在控制雪旺细胞的发育过程中,从增殖到分化和髓鞘内稳态中起到的阶段特异性功能。Jiang M Rao R Wang J Wang J1 Xu L Wu LM Chan JR Wang H Lu QR 聂昊(编译) 2018神经损伤与功能重建2018,13,5:2
5Quantitative assessment of resource-use efficient cropping systems: a case study for Ansai in the Loess Plateau of China显示文摘Lu C H van htersum M K Rabbinge R 2003European Journal of Agronomy2003,19,2:1
6A new kinetic modal for the NO-carbon reaction 显示文摘Li Y H Radovic L R Lu G Q 1999Chemical Engineering Science1999,,54:1
7Eigenvalues and the one-dimensional p-Laplacian显示文摘AGARWAL R P LU H S O'REGAN D 2002J Math Anal Appl2002,266,:1
8CD58/LFA-3 and IL-12 provided by activated monocytes are critical in the in vitro expansion of CD56+ T cells显示文摘Lopez R D Waller E K Lu P H 2001Cancer Immunol Immunother2001,49,12:1
9Hypoxia-inducible Factor 1 Activation by Aerobic Glycolysis Implicates the Warburg Effect in Carcinogenesis 显示文摘Lu H Forbes R A Verma A 2002J Biol Chem2002,277,23:1
10A novel alkaline and low-temperature lipase of Burkholderia cepacia isolated from Bohai in China for detergent formulation 显示文摘Wang H K Liu R J Lu F P 2009Annals of Microbiology2009,59,1:1
11Chromosomal regions associated with segregation distortion in maize 显示文摘Lu H Romero Severson J Bernardo R 2002Theoreti cal and Applied Genetics2002,105,62:1
12Talanta显示文摘Li Y H Niu W F Lu J R 200771:11242007,71,:1
13Preparation and characterization of NaSm9(SiO4)6O2 powders with infrared absorptive properties显示文摘ZHANG W Y LU C H NI Y R 2011Materials Letters2011,65,11:1
14Tissue-specific expression of herpessimplex virus thymidine kinase gene delivered by adeno-associatedvirus inhibits the growth of human hepatocellular carcinoma inathymic mice显示文摘Su H Lu R Chang JC 1997Proc Natl Acad Sci U S A1997,94,13:1
15Study of preparation and properties on solid superacid sulfated titanic-silica nanomatefials显示文摘YANG H LU R WANG L 2003Materials Letters2003,57,:1
16Effects of strain, sWain rate and temperature on deformation twinning in a Cu-Zn alloy 显示文摘Xiao G H Tao N R Lu K 2008Scripta Materialia2008,59,9:1
17Wind loads on square cylinder in homogeneous turbulent flows 显示文摘Cheng C M Lu P C Chen R H 1992Journal of Wind Engineering and Industrial Aerodynamics1992,4144,:1
18The effect of volume fraction of WC particles on erosion resistance of WC reinforced iron matrix surface composites 显示文摘Zhou R Jiang Y H Lu D H 2003Wear2003,255,:1
19Silk matrix for tissue engineered anterior cruciate liga-ents显示文摘Altmana G H Horan R L Lu H H 2002Biomaterials2002,,23:1
20Chromosomal regions associated with segregation distortion in maize显示文摘Lu H Romero severson J Bernardo R 2002Theoretical and Applied Genetics2002,105,:1
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