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90篇 您的检索式:作者名="Lai Ko"
    题名 作者 年代 出处 被引量
1Comparison of prevalence of virulence factors for Klebsiella pneumoniae liver abscesses between isolates with capsular K1/K2 and non-K1/K2 serotypes显示文摘Wen-Liang Yu Wen-Chien Ko Kuo-Chen Cheng Ching-Chien Lee Chien-Cherng Lai Yin-Ching Chuang 2008Diagnostic Microbiology & Infectious Disease2008,,1:2
2Leptin Signaling Protects NK Cells from Apoptosis During Development in Mouse Bone Marrow显示文摘增加的证据在有免疫力的反应显示 leptin 的一个角色,但是发信号的 leptin 是否涉及在骨头髓(BM ) 调整 NK 房间开发,仍然保持大部分不清楚。在这研究,我们在在 prediabetic 的缺乏的 db/db 老鼠上演的 leptin 受体的 BM 描绘了 NK 房间区别和成熟。尽管 BM 细胞质类似于控制值, NK 房间的全部的数字严重地在变异的鼠标被减少。db/db BM 房间的流动 cytometric 分析揭示了在区别的各种各样的阶段开发 NK 房间的显著地减少的频率。显著地显示的 BM db/db NK 房间增加了 apoptosis,但是维持了正常房间骑车地位和 proliferative 能力。而且, recombinant leptin 能显著地在文化从野类型的老鼠提高 NK 房间的幸存。NK 房间上的进一步的检查功能的活动证明 db/db NK 房间与显著地增加的 IL-10 展出了正常内在的 cytotoxicity 生产。一起拿,我们的调查结果建议发信号的 leptin 经由在老鼠 BM 提高不成熟的 NK 房间的幸存调整 NK 房间开发。Cherry Kam Chun Lo Queenie Lai Kwan Lam Min Yang King-Hung Ko Lingyun Sun Rui Ma Shengjun Wang Huaxi Xu Sidney Tam Chang-You Wu Bo-Jiang Zheng Liwei Lu 2009Cellular & Molecular Immunology2009,6,5:2
3Phenylketonuria in Hong Kong Chinese: a call for hyperphenylalaninemia newborn screening in the Special Administrative Region, China显示文摘Hyperphenylalaninemia 是在 15 000 实时出生影响约 1 的新陈代谢的最普通的先天的错误之一。在汉语之中, BH4 缺乏导致 hyperphenylalaninemia 比在白种人普通得多。准确诊断为治疗并且基因建议是重要的。在 2000,为苯酮尿的新生的屏蔽由在在整个整个国家的中国的法律是强制的。然而,它还没在香港特别行政区的新生的屏蔽节目被包括,中国。在香港汉语之中的 hyperphenylalaninemia 上的出版数据大部分正在缺乏。我们与严重 6-pyruvoyl-tetrahydropterin synthase (PTPS ) 报导一个 1 岁的香港中国女孩缺乏。病人与婴儿的 hypotonia 介绍了并且作为服的麻痹被误诊。她有的很温和的 hyperphenylalaninemia (95 mol/L ) ,显著地高的 phenylalnine-to-tyrosine 比率(3.1 ) ,和 1109 mlU/L 的提高的催乳激素。基因分析证实了同型结合的已知的引起疾病的变化磅 NM_000317.1:c.259CT;NP_000308.1:p。在 proband 的 P87S。根据我们的本地经验,当 PTPS 缺乏的 hyperphenylalaninemia 线索的估计的流行被报导在 29 542 实时出生,不是本氨基丙酸 hydroxylase 的一个单个案例是 1 时,缺乏被报导了。而且,有在社区以及在医药专业人员之中的继承新陈代谢的疾病的了解的一般缺乏。很经常,临床的怀疑的一个低索引将在诊断,多重不必要、昂贵的调查,延长病态和焦虑导致延期到影响的家庭。我们强烈建议为 hyperphenylalaninemia 屏蔽的那个扩展新生儿应该为在香港特别行政区出生的每个婴儿被实现,中国。Chloe Miu Mak Chun-hung Ko Ching-wan Lam Wai-ling Lau Wai-kwan Siu Sammy Pak-lam Chen Chun-yiu Law Chi-kong Lai Chak-man Yu Albert Yan-wo Chan 2011Chinese Medical Journal2011,,16:2
4TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory显示文摘Lai KO Wong AS Cheung MC 2012Nat Neurosci2012,15,11:1
5Induction of NG108-15 cell differentiation by human marrow stromal cells显示文摘Ho SH So LH Lai KO 1998Neuroreport1998,9,:1
6Effects of fish oil on inflammatory modulation in surgical intensive care unit patients 显示文摘Han YY Lai SL Ko WJ 2012Nutr Clin Pract2012,27,1:1
7Temporal relationship between air pollutants and hospital admissions for chronic obstructive pulmonary disease in Hong Kong 显示文摘Ko FW Tam W Wong TW Chan DP TungAH Lai CK Hui DS 2007Thorax2007,62,9:1
8Color Doppler tissue imaging for evaluation of right ventricular systolic function in patients with congenital heart disease 显示文摘Lytrivi ID Lai WW Ko HH 2005J Am Soc Echocardiogr2005,18,:1
9Crystal structures of Bacillusalkaline phytase in complex with divalent metal ions and inositolhexasu!fate显示文摘ZENG Y F KO T P LAI H L 2011J Mol Biol2011,409,2:1
10Cloning and expression of a novel neurotrophin,NT-7,fromcarp显示文摘Lai KO Fu WY Ip FC et a1 1998Mol Cell Neurosci1998,11,12:1
11Changes in yolk states of duck egg during long-term brining显示文摘LAI K M CHI S P KO W C 1999J Agric & Food Chemi1999,47,2:1
12New organosilicon maxillofacial prosthetic materials显示文摘Lai JH Wang LL Ko CC 2002Dent Mater2002,18,3:1
13Temporal relationship between air pollutant and hospital admissionsfor chronic obstructive pulmonary disease in Hong Kong显示文摘Ko FW Tam W Wong TW Chan DP Tung AH Lai CK Hui DS 2007Tho-rax2007,62,9:1
14TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory显示文摘Lai KO Wong AS Cheung MC 2012Nat Neurosci2012,15,11:1
15Alterations in serum fatty acid concentrations and desaturase activities in Bietti crystalline dystrophy unaffected by CYP4V2 genotypes 显示文摘LAI TY CHU KO CHAN KP NG TK YAM GH LAM DS 2010Invest Ophthalmol Vis Sci2010,51,2:1
16Factors associated with difference in prevalence of asthma in children from three cities in China: multicentre epidemiological survey显示文摘Wong GW Ko FW Hui DS Fok TF Carr D von Mutius E Zhong NS Chen YZ Lai CK 2004BMJ2004,329,7464:1
17Differential aqueous and vitreous concentrations of moxifloxacin and ofloxacin after topical administration one hour before vitrectomy 显示文摘Lai WW Chu KO Chan KP 2007Am J Ophthalmol2007,144,:1
18Muhicenter study in Taiwan of the in vitro activities of nemonoxacin, tigeeycline, doripenem, and other antimicrobial agents against clinical isolates of various Noeardia species 显示文摘Lai CC Liu WL Ko WC 2011Antimicrob Agents Chemother2011,55,5:1
19Cloning and expression of a novel neurotrophin, NT-7, from carp 显示文摘Lai KO Fu WY Ip FC 1998Mol Cell Neurosci1998,11,12:1
20Lupane-glycoside of Acanthopanax trifoliatus forma tristigmatis leaves显示文摘Yook C S Chang S Y Lai J H Ko S K Jeong J H Nohara T 1999Archives of Pharmacal Research1999,22,6:1
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