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| 1 | Enamel microabrasion: An overview of clinical and scientific considerations显示文摘Superficial stains and irregularities of the enamelare generally what prompt patients to seek dental intervention to improve their smile. These stains or defects may be due to hypoplasia, amelogenesis imperfecta, mineralized white spots, or fluorosis, for which enamel microabrasion is primarily indicated. Enamel microabrasion involves the use of acidic and abrasive agents, such as with 37% phosphoric acid and pumice or 6% hydrochloric acid and silica, applied to the altered enamel surface with mechanical pressure from a rubber cup coupled to a rotatory mandrel of a lowrotation micromotor. If necessary, this treatment can be safely combined with bleaching for better esthetic results. Recent studies show that microabrasion is a conservative treatment when the enamel wear is minimal and clinically imperceptible. The most important factor contributing to the success of enamel microabrasion is the depth of the defect, as deeper, opaque stains, such as those resulting from hypoplasia, cannot be resolved with microabrasion, and require a restorative approach. Surface enamel alterations that result from microabrasion, such as roughness and microhardness, are easily restored by saliva. Clinical studies support the efficacy and longevity of this safe and minimally invasive treatment. The present article presents the clinical and scientific aspects concerning the microabrasion technique, and discusses the indications for and effects of the treatment, including recent works describing microscopic and clinical evaluations. | Núbia Inocencya Pavesi Pini Daniel Sundfeld-Neto Flavio Henrique Baggio Aguiar Renato Herman Sundfeld Luis Roberto Marcondes Martins José Roberto Lovadino Débora Alves Nunes Leite Lima | 2015 | World Journal of Clinical Cases2015，3，1： | 6 |
| 2 | Helicobacter pylori and EBV in gastric carcinomas:Methylation status and microsatellite instability显示文摘AIM:To verify the methylation status of CDH1, DAPK, COX2, hMLH1 and CDKN2A genes and to evaluate their association with Helicobacter pylori (H. pylori)-cagA+ and Epstein Barr virus (EBV) infections in gastric adenocarcinomas.METHODS: Methylation-specific PCR (MSP) assay was performed in 89 primary gastric carcinomas (intestinal and diffuse types). Microsatellite instability (MSI) analysis was performed using the BAT26 primer set and PCR products were analyzed with the ABI PRISM 3100 Genetic Analyzer using Genescan 3.7 software (Applied Biosystems). Detection of H. pylori and genotyping were performed by PCR, using specifi c primers for ureaseC and cagA genes. The presence of EBV was assessed by in situ hybridization. Statistical analyses were performed using the χ2 or Fisher's exact test.RESULTS: The most frequent hypermethylated gene was COX-2 (63.5%) followed by DAPK (55.7%), CDH1 (51%), CDKN2A (36%) and hMLH1 (30.3%). Intestinal and diffuse adenocarcinomas showed different methylation profiles and there was an association between methylation of E-CDH1 and H. pylori-cagA+ in the intestinal adenocarcinoma type. MSI was correlated with hMLH1 methylation. There was an inverse correlation between DAPK hypermethylation and MSI.CONCLUSION: We found a strong association between CDH1 methylation and H. pylori-cagA+ in intestinal-type gastric cancer, association of MSI and better prognosis and an heterogeneous COX-2 overexpression. | Adriana Camargo Ferrasi Nídia Alice Pinheiro Silvia Helena Barem Rabenhorst Otávia Luisa Caballero Maria Aparecida Marchesan Rodrigues Fabrício de Carvalho Celso Vieira de Souza Leite Marcia Valéria Pitombeira Ferreira Marcos Aurélio Pessoa Barros Maria Inês de Moura Campos Pardini | 2010 | World Journal of Gastroenterology2010，16，3： | 6 |
| 3 | Helicobacter pylori Induces Increased Expression of Toll‐Like Receptors and Decreased Toll‐Interacting Protein in Gastric Mucosa that Persists Throughout Gastric Carcinogenesis显示文摘 | Pedro Pimentel‐Nunes Nádia Gon?alves Inês Boal‐Carvalho Luís Afonso Paula Lopes Roberto Roncon‐Albuquerque Rui Henrique Luís Moreira‐Dias Adelino F. Leite‐Moreira Mário Dinis‐Ribeiro | 2012 | Helicobacter2012，，1： | 2 |
| 4 | CT evaluationof appendicitis and its complications:Imaging techniques and key diagnostic findings显示文摘 | Pinto Leite N Pereira JM Cunha R | 2005 | AJR Am J Roentgenol2005，184，2： | 1 |
| 5 | A multi scale directional operator and morphological tools for Reconnecting broken ridges in finger- print images显示文摘 | Oliveira M A Leite N J | 2008 | Pattern Recognition2008，41，： | 1 |
| 6 | Gen- otyping of Mycobacterium tuberculosis isolates from a low-endemic setting in northwestern state of Parana in Southern Brazil 显示文摘 | Noguti E N Leite C Q Malaspina AC | 2010 | Mem Inst Oswaldo Cruz2010，105，6： | 1 |
| 7 | Hydrocracking of Phenanthrene over Pt/Si O2-Al2O3,Pt/H-Y,Pt/H-βand Pt/H-ZSM-5Catalysts:Reaction Pathway and Products Distribution显示文摘 | Benazzi E Leite L Marchal G N | 2000 | Stud Surf Sci Catal2000，130，： | 1 |
| 8 | Evaluation methods and accuracy in probabilistic load Flow solutions显示文摘 | Allan R N Leite A M | 1981 | IEEE Trans on PAS1981，100，5： | 1 |
| 9 | CT evaluation of appendicitis and its complications:imaging techniques and key diagnostic findings显示文摘 | Pinto Leite N Pereira J M Cunha R | | 0，，02： | 1 |
| 10 | CT evaluation of appendici- tis and its complication imaging techniques and key diagnostic finding 显示文摘 | Pinto Leite N Pereira JM Cunha R | 2005 | AJR2005，185，2： | 1 |
| 11 | CT evaluation of appendicitis and its complications:imaging techniques and key diagnostic findings显示文摘 | Pereira JM Cunha R | 2005 | A JR Am J Roentgenol2005，185，2： | 1 |
| 12 | Cross-sectional imaging of extranodal involvement in abdominopelvic lymphoproliferative malignancies显示文摘 | Leite NP Kased N Hanna RF | 2007 | Radiographics2007，27，6： | 1 |
| 13 | Antiglycine-receptor encephalomyelitis with rigidity 显示文摘 | Mas N Saiz A Leite MI | 2011 | J Neurol Neurosurg Psychiatry2011，82，12： | 1 |
| 14 | Autoimmunizing mecha- nisms in thymoma and thymus 显示文摘 | Willcox N Leite MI Kadota Y | 2008 | Ann N Y Acad Sci2008，1132，： | 1 |
| 15 | Type 2 heat-labile enterotoxin (LT-II)-producing Escherichia coli isolated from ostriches with diarrhea显示文摘 | Ana Rita M. Nardi Márcia R. Salvadori Lia T. Coswig Maria Sílvia V. Gatti Domingos S. Leite Geórgio F. Valadares Manoel Garcia Neto Rubén P. Shocken-Iturrino Jesús E. Blanco Tomomasa Yano | 2004 | Veterinary Microbiology2004，，3： | 1 |
| 16 | Evaluation methods and accuracy in probabilistic load flow solutions 显示文摘 | Allan R N Leite de Silva A M Burchett R C | 1981 | IEEE Trans on Power Apparatus and Systems1981，100，5： | 1 |
| 17 | Probabilistic Load Flow Techniques Applied to Power System Expansion Planning 显示文摘 | Leite da Silva A M Ribeiro S M P Allan R N | 1990 | IEEE Transactions on Power Systems1990，5，4： | 1 |
| 18 | Genomic typing of canine parvovirus circulating in the State of Rio de Janeiro, Brazil from 1995 to 2001 using polymerase chain reaction assay 显示文摘 | Costa A P Leite J P G Labarthe N V | 2005 | Veterinary Research Communications2005，29，： | 1 |
| 19 | Three-phase transformer modeling using a vector hysteresis model and including the eddy current and the anomalous losses显示文摘 | DA LUZ V M F LEITE J V BENABOU A SADOWSKI N | | 0，，08： | 1 |
| 20 | Factors associated with abnormal T-wave axis and increased QRS-T angle in type 2 diabetes 显示文摘 | CARDOSO C R LEITE N C SALLES G F | 2013 | Acta Diabeto12013，50，6： | 1 |
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