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| 1 | Seasonal water storage change of the Yangtze River basin detected by GRACE显示文摘US-Germany co-sponsered satellite gravimetry mission GRACE (Gravity Recovery And Climate Experiment), launched in March 2002, has been producing monthly time series of Earth gravity models up to degree and order of 120. The GRACE mission consists of two identical satellites flying on an almost polar orbit with an altitude of about 300-500 km and satelite-to-satellite ranging of about 220 km. Thanks to the payloads of space-borne GPS receivers, accelerometers and high-precision K-band satelite-to-satellite ranging mesurements, GRACE gravity models are expected to achieve more than one order of magnitude of improvement over previous models at spatial scales of a few hundred kilometers or larger. Recovery of surface mass re-distribution based on GRACE’s time-varying gravity models is applied to studies in solid Earth geophysics, oceanography, climatology and geodesy. At secular time scales, GRACE is expected to provide valuable information on global ice changes, whose variations have profound influences on global climate, and in particular, on sea level changes. At seasonal time scales, GRACE is expected to reveal surface water changes with an ac- curacy of less than 1 cm, or ocean bottom pressure changes with an accuracy of less than 1 mbar (1 mbar =102 Pa). These surface mass redistribution measurements would impove our understanding of the global and regional mass and energy cycles that are critical to human life. Using 15 GRACE monthly gravity models covering the period from April 2002 to December 2003, this study compares seasonal water storage changes recovered from GRACE data and hydrology models at global and regional scales, with particular focus on the Yangtze River basin of China. Annual amplitude of 3.4 cm of equivalent water height change is found for the Yangtze River basin with maximum in Spring and Autumn, agreeing with two state-of-the-art hydrology models. The differences between GRACE re- sults and model predictions are less than 1-2 cm. We conclude that satellite gravimetry has huge potentials in monitering water storage changes in large river basins such as Yangtze. | HU Xiaogong1, CHEN Jianli1,2, ZHOU Yonghong1, HUANG Cheng1 & LIAO Xinhao1 1. Center for Astro-geodynamics Research, Shanghai Astronomical Observatory, National Astronomical Observatories, Shanghai 200030, China 2. Center for Space Research, University of Texas at Austin, 3925 W. Braker Lane, Suite 200, Austin, TX78750, USA | 2006 | Science China Earth Sciences2006，49，5： | 29 |
| 2 | Microwave-assisted Polymerization of D,L-Lactide with Stannous Octanoate as Catalyst显示文摘Poly (lactic acid) (PLA) was synthesized by microwave-assisted ring-opening poly- merization of D, L-lactide with stannous octanoate (SnOct2) as catalyst. Its weight-average molar mass (Mw) ranged from 39000 to 67000 and the polydispersity index from 1.3 to 1.7. The polymerization rate was much faster than that of the conventional thermal polymerization. A degradation of newly formed PLA in reaction mixture by microwave irradiation was observed. | Li Jian LIU* Chao ZHANG, Li Qiong LIAO, Xu Li WANG, Ren Xi ZHUO Department of Polymer Science, College of Chemistry and Molecular Science, Wuhan University The Research Laboratory of SEDC of Biomedical Polymer Materials at Wuhan University, Wuhan 430072 | 2001 | Chinese Chemical Letters2001，12，8： | 7 |
| 3 | In vitro inhibition of soft-rotting bacteria by EDTA and nisin and in vivo response on inoculated fresh cut carrots显示文摘 | Liao ChingHsing Hotchkiss AT Liao CH | 1998 | Plant Disease1998，82，5： | 1 |
| 4 | In vitro inhibition of soft-rotting bacteria by EDTA and nisin and in vivo response on inoculated fresh cut carrots显示文摘 | Wells JM Liao ChingHsing Hotchkiss AT Liao CH | 1998 | Plant Disease1998，82，5： | 1 |
| 5 | Synthesis of hierarchical mesoporous zireania fiber by using collagen fiber as a template显示文摘 | DENG D H LIAO X P LIU X et at | 2008 | Journal of Materi- als Research2008，23，12： | 1 |
| 6 | Structural parameterization and functional prediction of antigenic polypeptome sequences with biological activity through quantitative sequence-activity models (QSAM) by molecular electronegativity edge-distance vector (VMED)显示文摘Only from the primary structures of peptides, a new set of descriptors called the molecular electro-negativity edge-distance vector (VMED) was proposed and applied to describing and characterizing the molecular structures of oligopeptides and polypeptides, based on the electronegativity of each atom or electronic charge index (ECI) of atomic clusters and the bonding distance between atom-pairs. Here, the molecular structures of antigenic polypeptides were well expressed in order to propose the auto-mated technique for the computerized identification of helper T lymphocyte (Th) epitopes. Furthermore, a modified MED vector was proposed from the primary structures of polypeptides, based on the ECI and the relative bonding distance of the fundamental skeleton groups. The side-chains of each amino acid were here treated as a pseudo-atom. The developed VMED was easy to calculate and able to work. Some quantitative model was established for 28 immunogenic or antigenic polypeptides (AGPP) with 14 (1― 14) Ad and 14 other restricted activities assigned as '1'(+) and '0'(-), respectively. The latter comprised 6 Ab(15-20), 3 Ak(21-23), 2 Ek(24-26), 2 H-2k(27 and 28) restricted sequences. Good results were obtained with 90% correct classification (only 2 wrong ones for 20 training samples) and 100% correct prediction(none wrong for 8 testing samples); while con-trastively 100% correct classification (none wrong for 20 training samples) and 88% correct classification (1 wrong for 8 testing samples). Both stochastic samplings and cross valida-tions were performed to demonstrate good performance. The described method may also be suitable for estimation and prediction of classes I and II for major histocompatibility an-tigen (MHC) epitope of human. It will be useful in immune identification and recognition of pro-teins and genes and in the design and devel-opment of subunit vaccines. Several quantitative structure activity relationship (QSAR) models were developed for various oligopeptides and polypeptides including 58 dipeptides and 31 pentapeptides with angiotensin converting enzyme (ACE) inhibition by multiple linear regression (MLR) method. In order to explain the ability to characterize molecular structure of polypeptides, a molecular modeling investigation on QSAR was performed for functional prediction of polypeptide sequences with anti-genic activity and heptapeptide sequences with tachykinin activity through quantitative se-quence-activity models (QSAMs) by the molecular electronegativity edge-distance vector (VMED). The results showed that VMED exhibited both excellent structural selectivity and good activity prediction. Moreover, the results showed that VMED behaved quite well for both QSAR and QSAM of poly-and oli-gopeptides, which exhibited both good estimation ability and prediction power, equal to or better than those reported in the previous references. Finally, a preliminary conclusion was drwan: both classical and modified MED vectors were very useful structural descriptors. Some suggestions were proposed for further studies on QSAR/QSAM of proteins in various fields. | LI ZhiLiang1,2, WU ShiRong1,2, CHEN ZeCong1,2, YE Nancy1,2, YANG ShengXi1,2, LIAO ChunYang1,2, ZHANG MengJun1,2,3, YANG Li1,2, MEI Hu1,2,4, YANG Yan1,2, ZHAO Na1,2, ZHOU Yuan1,2, ZHOU Ping1,2, XIONG Qing1,2, XU Hong1,2, LIU ShuShen1,2, LING ZiHua1,2, CHEN Gang1,2,4 & LI GenRong1,2 1 College of Chemistry and Chemical Engineering/Key Laboratory for Chemobiomedical Science and Engineering under Chongqing Municipality, College of Life Science and Biological Engineering/Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education, Chongqing University, Chongqing 400044, China 2 State Key Laboratory for Chemobiosensors and Chemobiometrics under MOST at Hunan University, Changsha 410012, China 3 Department of Medical Analysis/PLA Center of Bioinformatics Immunology, Surgeon Third University, Chongqing 400031, China 4 Technology Centre for Life Sciences, Singapore Polytechnic, 500 Dover Road, Singapore 139651, Singapore | 2007 | Science China(Life Sciences)2007，50，5： | 1 |
| 7 | Augmenter of liver regeneration attenua- tes tubular cell apoptosis in acute kidney injury in rats : the possible mechanisms 显示文摘 | Liao XH Chen GT Li Y et at | 2012 | Ren Fail2012，34，5： | 1 |
| 8 | Thyroid hormone receptor represses miR-17 expression to enhance tumor metastasis in human hepatoma cells显示文摘 | Lin YH Liao CJ Huang YH et at | 2013 | Oncogene2013，32，38： | 1 |
| 9 | Distribution and migration of heavy metals in soil and crops affected by acid mine drainage: Public health implications in Guangdong Province, China 显示文摘 | LIAO J B WEN Z W WE1 C H et at | 2016 | Ecotoxicology and Environmental Safety2016，124，11： | 1 |
| 10 | Immunodeficient mouse models with different disease profiles by in vivo infection with the same clinical isolate of enterovirus 71 显示文摘 | Liao CC Liou AT Chang YS Wu SY Chang CS Lee CK Kung JT Tu PH Yu YY Lin CY Lin JS Shih C | 2014 | J Virol2014，88，12： | 1 |
| 11 | IsoRankN: spectral methods for global alignment of multiple protein networks显示文摘 | LIAO C-S LU K H BAYM M et at | 2009 | Biocomputing2009，25，12： | 1 |
| 12 | Immunodeficient mouse models with different disease profiles by in vivo infection with the same clinical isolate of enterovirus 71 显示文摘 | Liao CC Liou AT Chang YS Wu SY Chang CS Lee CK Kung JT Tu PH Yu YY Lin CY Lin JS Shih C | 2014 | J Virol2014，88，12： | 1 |
| 13 | Trichorionic triplet pregnancies at 10-14 weeks: outcome after embryo reduction compared to expectant management 显示文摘 | Papageorghiou AT Liao AW Skentou C | 2002 | J Matern Fetal Neonatal Med2002，11，5： | 1 |
| 14 | Trichorionic triplet pregnancies at 10-14 weeks:outcome after embryo reduction compared to expectant management显示文摘 | Papageorghiou AT Liao AW Skentou C | 2002 | J Matern Fetal Neonatal Med2002，11，5： | 1 |
| 15 | Uhrasound molecular imaging of angiogenesis induced by mutant forms of hypoxia-inducible factor-let 显示文摘 | XieJ Liao Y Yang L et at | 2011 | Cardiovasc Res2011，92，2： | 1 |
| 16 | Tissue responses to na- creous implants in rat femur: an in situ hybridization and histo- chemical study 显示文摘 | Liao H Mutvei H Hanunarstrom L et at | 2002 | Biomaterials2002，23，13： | 1 |
| 17 | Smooth muscle targeted knockout ofcormexin 43 enhances neointimal formation in response to vascular injury 显示文摘 | Liao Y Regan CP Manabe I at al | 2007 | Arterioscler Thromb VascBiol2007，27，5： | 1 |
| 18 | LDL induces transcription factor activator protein-1 in human endothelial cells显示文摘 | Zhu Y Lin JH Liao HL at al | 1998 | Arterioscler Thromb Vasc Biol1998，18，3： | 1 |
| 19 | Transcriptional and post-transcriptional regulation of proangiogenic factors by the unfolded protein response 显示文摘 | PEREIRA ER LIAO N NEALE GA et at | 2010 | PIoS One2010，5，12： | 1 |
| 20 | A new LDA-based face recognition system which can solve the small sample size problem 显示文摘 | Chen Li-Fen Mark Liao Hong-Yuan Ko Ming-Tat et at | 2000 | Pattern Recognition2000，33，： | 1 |
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