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| 1 | Comparative effectiveness of i-SCAN^(TM) and high-definition white light characterizing small colonic polyps显示文摘AIM:To evaluate accuracy of in vivo diagnosis of adenomatous vs non-adenomatous polyps using i-SCAN digital chromoendoscopy compared with high-definition white light.METHODS:This is a single-center comparative effectiveness pilot study.Polyps(n = 103) from 75 averagerisk adult outpatients undergoing screening or surveillance colonoscopy between December 1,2010 and April 1,2011 were evaluated by two participating endoscopists in an academic outpatient endoscopy center.Polyps were evaluated both with high-definition white light and with i-SCAN to make an in vivo prediction of adenomatous vs non-adenomatous pathology.We determined diagnostic characteristics of i-SCAN and highdefinition white light,including sensitivity,specificity,and accuracy,with regards to identifying adenomatous vs non-adenomatous polyps.Histopathologic diagnosis was the gold standard comparison.RESULTS:One hundred and three small polyps,detected from forty-three patients,were included in the analysis.The average size of the polyps evaluated in the analysis was 3.7 mm(SD 1.3 mm,range 2 mm to 8 mm).Formal histopathology revealed that 54/103(52.4%) were adenomas,26/103(25.2%) were hyperplastic,and 23/103(22.3%) were other diagnoses include 'lymphoid aggregates','non-specific colitis,' and 'no pathologic diagnosis.' Overall,the combined accuracy of endoscopists for predicting adenomas was identical between i-SCAN(71.8%,95%CI:62.1%-80.3%) and high-definition white light(71.8%,95%CI:62.1%-80.3%).However,the accuracy of each endoscopist differed substantially,where endoscopist A demonstrated 63.0% overall accuracy(95%CI:50.9%-74.0%) as compared with endoscopist B demonstrating 93.3% overall accuracy(95%CI:77.9%-99.2%),irrespective of imaging modality.Neither endoscopist demonstrated a significant learning effect with i-SCAN during the study.Though endoscopist A increased accuracy using i-SCAN from 59%(95%CI:42.1%-74.4%) in the first half to 67.6%(95%CI:49.5%-82.6%) in the second half,and endoscopist B decreased accuracy using i-SCAN from 100%(95%CI:80.5%-100.0%) in the first half to 84.6%(95%CI:54.6%-98.1%) in the second half,neither of these differences were statistically significant.CONCLUSION:i-SCAN and high-definition white light had similar efficacy predicting polyp histology.Endoscopist training likely plays a critical role in diagnostic test characteristics and deserves further study. | Johanna L Chan Li Lin Michael Feiler Andrew I Wolf Diana M Cardona Ziad F Gellad | 2012 | World Journal of Gastroenterology2012，18，41： | 3 |
| 2 | 欧洲和中国的心脏与肾脏远程缺血预适应研究:一项随机对照试验显示文摘远程缺血预适应(remote ischemic preconditioning,RIPC)对经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术后造影剂肾病(contrast-induced nephropathy,CIN)的潜在保护作用尚待确定。该研究为双盲、随机、安慰剂对照的多中心研究,纳入年龄〈85岁,肾清除率为30~60mL/(min·1.73m^2)的有临床适应证的患者,除了直接PCI外均按1∶1给予RIPC或标准治疗。主要终点是CIN的发生率。次要终点是围手术期心肌梗死(peri-procedural myocardial infarction,PMI)的发生率。 | 刘青 叶鹏 Moretti C Cerrato E Cavallero E Lin S Rossi ML Picchi A Sanguineti F Ugo F Palazzuoli A Bertaina M Presbitero P Shao-Liang C Pozzi R Giammaria M Limbruno U Lefèvre T Gasparetto V Garbo R OmedèP Sheiban I Escaned J Biondi-Zoccai G Gaita F Perl L D'Ascenzo F | 2018 | 中华高血压杂志2018，26，4： | 3 |
| 3 | Pitfalls in the computed tomographic evaluation of the lumbar spine in disc disease显示文摘 | Braun I F Lin J P George A E | 1984 | Neuroradiology1984，26，1： | 1 |
| 4 | Cloning and sequencing of the eel- lulose synthase catalytic subunit gene of Acetobacter xylinum 显示文摘 | SAXENA I M LIN F C BROWN R M | 1990 | Plant Mol Bio11990，15，5： | 1 |
| 5 | Effects of oxidised dietary oil and antioxidant supplementation on broiler growth and meat stability显示文摘 | Lin C F Asghar A Gray J I | 1989 | British Poultry Science1989，30，4： | 1 |
| 6 | Self-regulating fuzzy control for forward DC-DC converters using an 8-bit microcontroller 显示文摘 | Hsu C F Chung I F Lin C M | 2009 | lET Power Electonics2009，2，1： | 1 |
| 7 | Cloning and sequencing of the cellulose synthase catalytic subunit gene of Acetobacter xylinum显示文摘 | Lin F C Brown RM Jr | 1990 | Plant Mol Biol1990，15，： | 1 |
| 8 | Eeg-based assessment of driver cognitive responses in a dynamic virtual-reality driving environment显示文摘 | LIN C T CHUNG I F KO L W | 2007 | IEEE Transactions on Biomedical Engineering2007，54，7： | 1 |
| 9 | Effect of soil pH and clay content on the zinc soil test interpretation for corn显示文摘 | Lins I D G Cox F R | 1988 | Soil Sci A M J1988，52，： | 1 |
| 10 | EEG- based assessment of driver cognitive responses in a dynamic virtual-reality driving environment显示文摘 | LIN C T CHUNG I F KO L W | 2007 | IEEETransactions on Biomedical Engineering2007，54，7： | 1 |
| 11 | Antitubercular constituents from the roots ofEngelhardtia roxburghiana 显示文摘 | Lin W Y Peng C F Tsai I L | 2005 | Planta Med2005，71，2： | 1 |
| 12 | Effects of particle size of BaTiO3 powder on the dielectric properties of BaTiO3/PVDF composites显示文摘 | Hsing H I Lin K Yen F Hwang C | 2001 | Journal of Material Science2001，36，： | 1 |
| 13 | Genome sequence and analysis of the tuber crop potato显示文摘 | Xu X Pan S Cheng S Zhang B Mu D Ni P Zhang G Yang S Li R Wang J Orjeda G Guzman F Tones M Lnzano R Ponce O Martinez D De la Cruz G Chakrabarti S K Patil V U Skryabin K G Kuznetsov B B Ravin N V Kolganova T V Beletsky A V Mardanov A V Di Genova A Bolser D M Martin D M Li G Yang Y Kuang H Hu Q Xiong X Bishop G J Sagredo B Mejia N Zagorski W Gromadka R Gawor J Szczesny P Huang S Zhang Z Liang C He J Li Y He Y Xu J Zhang Y Xie B Du Y Qu D Bonierbale M Ghislain M Herrera Mdel R Giuliano G Pietrella M Perrotta G Faeella P O 'Brien K Feingold S E Barreiro L E Massa G A Diambra L Whitty B R Vaillancourt B Lin H Massa A N Geoffroy M Lundback S DellaPenna D Buell C R Sharma S K Marshall D F Waugh R Bryan G J Destefanis M Nagy I Milbourne D Thomson S J Fiefs M Jacobs J M Nielsen K L Sonderkaer M Iovene M Tortes G A Jiang J Veilleux R E Bachem C W de Boer J Bonn T Kloosterman B van Eck H Datema E Hekkert B Goverse A van Ham R C Visser R G | 2011 | Nature2011，475，7355： | 1 |
| 14 | Real-time IP position controller design with torque feedforward control for PM synchronous motor显示文摘 | | 1997 | IEEE Trans on Ind Electron1997，44，3： | 1 |
| 15 | Cam-Clay plasticity, Part IV Implicit integration of anisotropic bounding surface model with nonlinear hyperelasticity and ellipsoidal loading function显示文摘 | BORJA R I LIN C MONTANS F J | 2001 | Computer Methods in Applied Mechanics and Engineering2001，190，2627： | 1 |
| 16 | Electrochemistry of gallium in the Lewis acidic aluminum chloride-1-methyl-3-ehtylimi-dazolium chloride room-temperature molten salt显示文摘 | Chen P Y Lin Y F Sun I W | 1999 | J Elec-trochem Soc1999，146，9： | 1 |
| 17 | A new random walk model for PCS networks显示文摘 | AKYILDIZ I F LIN Yibing LAI Weiru | 2000 | IEEE Journal on Selected Areas in Communications2000，18，7： | 1 |
| 18 | Vibration suppression for higlr-speed railway bridges using tuned mass dampers 显示文摘 | Wang J F Lin C C Lee I W | 2003 | International Journal of Solids and Structures2003，，40： | 1 |
| 19 | Inhibition of miR-146aprevents enterovirus-induced death by restoring the production of type I interferon显示文摘 | Ho B C Yu I S Lu L F Rudensky A Chen H Y Tsai C W Chang Y L Wu C T Chang L Y Shih S R Lin S W Lee C N Yang P C Yu S L | 2014 | Nat Commun2014，5，： | 1 |
| 20 | Constant elasticity of variance(CEV) option pricing model:integration and detailed derivation显示文摘 | Su Y L Lin T I Lee C F | 2008 | Mathematics and Coputers in Simulation2008，79，1： | 1 |
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